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VARYGDSDDPNYSDDDPTQLSNYAYGDYEQAPPPDAEPPVPWYRKPAALVGLGALGAVLIALIVFGLAKA ITGDSDSETTPTSSLTPVTTTSAPAAVPPATVTETASESATTTTEPTTTTTTTEPTTTTTTTTPTTTTTP STSVSTSTSTSTVTQTETQTETVTEPPPAPPTP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0270 | - | - | 100% (173) | hypothetical protein Mflv_0270 |
| M. gilvum PYR-GCK | Mflv_0276 | - | 2e-22 | 35.58% (208) | hypothetical protein Mflv_0276 |
| M. gilvum PYR-GCK | Mflv_0308 | - | 7e-20 | 37.20% (207) | hypothetical protein Mflv_0308 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2287c | - | 2e-15 | 32.50% (160) | hypothetical protein Mb2287c |
| M. tuberculosis H37Rv | Rv2264c | - | 2e-15 | 32.50% (160) | hypothetical protein Rv2264c |
| M. leprae Br4923 | MLBr_00877 | mmpS3 | 8e-13 | 30.67% (150) | hypothetical protein MLBr_00877 |
| M. abscessus ATCC 19977 | MAB_4279 | - | 8e-18 | 38.71% (155) | hypothetical protein MAB_4279 |
| M. marinum M | MMAR_0618 | - | 8e-33 | 46.33% (177) | hypothetical protein MMAR_0618 |
| M. avium 104 | MAV_4816 | - | 4e-15 | 34.34% (166) | hypothetical protein MAV_4816 |
| M. smegmatis MC2 155 | MSMEG_0700 | - | 2e-38 | 53.85% (169) | hypothetical protein MSMEG_0700 |
| M. thermoresistible (build 8) | TH_2748 | - | 7e-44 | 53.45% (174) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0583 | - | 3e-31 | 44.94% (178) | hypothetical protein MUL_0583 |
| M. vanbaalenii PYR-1 | Mvan_0627 | - | 6e-70 | 78.98% (176) | hypothetical protein Mvan_0627 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 MATGARPALGLSIGVTNLAAVAADHS-ITRKPVLTLYRQRPPEVGVPSEN
Rv2264c|M.tuberculosis_H37Rv MATGARPALGLSIGVTNLAAVAADHS-ITRKPVLTLYRQRPPEVGVPSEN
MAV_4816|M.avium_104 -MRDMSEPLGLSIGVANLVAARAGSVPVIRSSVLTLFEQRPTEVGLPDEN
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 PRLDEPGLVITDFVDRVGDSVGIVAADGSVYRSEALVADALLALAYTATG
Rv2264c|M.tuberculosis_H37Rv PRLDEPGLVITDFVDRVGDSVGIVAADGSVYRSEALVADALLALAYTATG
MAV_4816|M.avium_104 PNLTEPGLVLRGFVERVGDRAPLVAADGTKYLGAALTVEAVEAMARAVGY
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 GRALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLSLLPD
Rv2264c|M.tuberculosis_H37Rv GRALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLSLLPD
MAV_4816|M.avium_104 G----APITIAVPAYWSDDQFAALREEFFAQSDLAR----EGVAPMLVSD
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 AAAALYAIRADPGIPARGIVAVCDFGGSGTGITLVDAADEYRPVAATVRH
Rv2264c|M.tuberculosis_H37Rv AAAALYAIRADPGIPARGIVAVCDFGGSGTGITLVDAADEYRPVAATVRH
MAV_4816|M.avium_104 ATAALAMLRGTPGFPSDGVIALCDFGAGGTTVTLMDGRAGFAPVGPSLRY
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 QAFSGDLIDQSLLSYVMSELPGTGAFDPAGTSAIGSLTKLRIECRKAKER
Rv2264c|M.tuberculosis_H37Rv QAFSGDLIDQSLLSYVMSELPGTGAFDPAGTSAIGSLTKLRIECRKAKER
MAV_4816|M.avium_104 TDFSGDAIDQLVLDHLLASDVSTAMRG--GSGRIGSQSRLLGACRRAKEQ
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 LSSSTVTTLTDALGGDIRLTRNELEDTIRDSLDSVGRALEQTLARSGIRT
Rv2264c|M.tuberculosis_H37Rv LSSSTVTTLTDALGGDIRLTRNELEDTIRDSLDSVGRALEQTLARSGIRT
MAV_4816|M.avium_104 LSTAVAVTVAGAPGQGAQLTRAEFEQLISTPLDRFLDWCQEALRRNGIGN
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK -----------------------------------------------MAR
Mvan_0627|M.vanbaalenii_PYR-1 -----------------------------------------------MAR
TH_2748|M.thermoresistible__bu -----------------------------------------------VAV
MSMEG_0700|M.smegmatis_MC2_155 -----------------------------------------------MAN
MMAR_0618|M.marinum_M -----------------------------------------------MAR
MUL_0583|M.ulcerans_Agy99 -----------------------------------------------MAR
Mb2287c|M.bovis_AF2122/97 AELVAIVSVGGGANIPAVTTTLSGRFCVPVVRTPRPQLTAAFGGALWAAR
Rv2264c|M.tuberculosis_H37Rv AELVAIVSVGGGANIPAVTTTLSGRFCVPVVRTPRPQLTAAFGGALWAAR
MAV_4816|M.avium_104 STLRGVAIVGGGASIPLLTARLSGRFGVPVHSTAQPGLSAALGAATLGAQ
MAB_4279|M.abscessus_ATCC_1997 -----------------------------------------------MSY
MLBr_00877|M.leprae_Br4923 ---MSGPNPPGRENEESDSGNELSGELDPHNGVESVDELVPVPDSDLVTA
:
Mflv_0270|M.gilvum_PYR-GCK YGDSDDPN-YSDDDPTQLSNY-----------------------------
Mvan_0627|M.vanbaalenii_PYR-1 YGDSDDQNYYSDDEPTQLSNYGT---------------------------
TH_2748|M.thermoresistible__bu SRPPEDPSNYSDSEPTAYSDYTAGGS------------------------
MSMEG_0700|M.smegmatis_MC2_155 NYSDDEPTQYAHSYG---GDYGA---------------------------
MMAR_0618|M.marinum_M ----HDPPDYGAGDPTAYGNYGYGD-------------------------
MUL_0583|M.ulcerans_Agy99 ----HDPPDYGAGDPTAYGNYGYGD-------------------------
Mb2287c|M.bovis_AF2122/97 RPGDTSATVLTAVTSATATAPADAP------------ASVLQPALAWSEA
Rv2264c|M.tuberculosis_H37Rv RPGDTSATVLTAVTSATATAPADAP------------ASVLQPALAWSEA
MAV_4816|M.avium_104 YASGAAPTAAAAAAVETPTEMVGAGGLDMTQAAWAAQATDVDDALAWSQD
MAB_4279|M.abscessus_ATCC_1997 PEPPEDPTMFNQQYHDQ---------------------------------
MLBr_00877|M.leprae_Br4923 SDHTSETEVYSQAYSAPEAEHFTAVP------------------------
Mflv_0270|M.gilvum_PYR-GCK -------------------AYGDYEQAPPPDAEPPVPWYRKPAALVG---
Mvan_0627|M.vanbaalenii_PYR-1 -------------------GYGEYDQSP-TEADSATPWYRKPVALVS---
TH_2748|M.thermoresistible__bu ------------GGYVPGYGGGEYGGPPGPPEEPPVPWYRKPAALVA---
MSMEG_0700|M.smegmatis_MC2_155 -------------------DYGAYPPPDQPPAPEPVPWYRKPAALVG---
MMAR_0618|M.marinum_M -------------------QGGGYGQQP---PPEPTPGWRKPLALAG---
MUL_0583|M.ulcerans_Agy99 -------------------QRGGYGQQP---PPEPTPGWRKPLALAG---
Mb2287c|M.bovis_AF2122/97 DEDSHIGPAPGYTAARPSLSFDHDAHAEPEPKSPPIPWYRLPAVIITGTT
Rv2264c|M.tuberculosis_H37Rv DEDSHIGPAPGYTAARPSLSFDHDAHAEPEPKSPPIPWYRLPAVIITGTT
MAV_4816|M.avium_104 ADTSDE-PVP-YTGRDATGEYASEARRFDDVAAGGLPWYKRTALVLS---
MAB_4279|M.abscessus_ATCC_1997 ------------------------------EPDQPNPWYKQPAVLIA---
MLBr_00877|M.leprae_Br4923 ----------YVPADLRLYDYDESSVYDEPGAAPRWPWVVGVAAILAAIS
* :
Mflv_0270|M.gilvum_PYR-GCK --LGALGAVLIALIVFGLAKAITGDSD------------SETTPTSSLTP
Mvan_0627|M.vanbaalenii_PYR-1 --FGAVGALLIALVVFGLARAITGDST------------SDTTTTTPLTP
TH_2748|M.thermoresistible__bu --FGALGAVLLGLIVFALIRLTSGDDA------------SSETATTTTTT
MSMEG_0700|M.smegmatis_MC2_155 --LGALGALIVALVIYAVIQLFSSDDS------------SSTTSTTTSTT
MMAR_0618|M.marinum_M --WGVLIAVLIGLIIFGIIQLAHGRPTP-----------ASVTKTVTATM
MUL_0583|M.ulcerans_Agy99 --WGVLIAVLIGLIIFGIIQLAHGRPTP-----------ASVTKTVTATM
Mb2287c|M.bovis_AF2122/97 VAVLLVGAAVAIGLSTGDQPTAPGTPQRPGV-----TTTAAPPPSPAPAS
Rv2264c|M.tuberculosis_H37Rv VAVLLVGAAVAIGLSTGDQPTAPGTPQRPGV-----TTTAAPPPSPAPAS
MAV_4816|M.avium_104 --VAGAGAAVLIALVLAINLLLTKSTQ---------DRPTSPPSTPAPPQ
MAB_4279|M.abscessus_ATCC_1997 --LAGAGVAVVAVIAALIITRSDDKPAP-----------AGNTSSVSSTT
MLBr_00877|M.leprae_Br4923 -LVVSVSLLFTRTDTSKLSTPTTGRSTPPVQDEITTVKPPPPSTETSTAT
. . . . .
Mflv_0270|M.gilvum_PYR-GCK VTTTSAPAAVPPATVTETASESATTTTEPTTTTTTTEP-----TTTTTTT
Mvan_0627|M.vanbaalenii_PYR-1 VTTTSAPAVVPPATVTETA--TATTTTEPVTTTTTTEP-----TTTTTTT
TH_2748|M.thermoresistible__bu TTTTGAPVAPPPATVTQTVPPATTTPAEEPSPPPTTTQ-----TPTTTTT
MSMEG_0700|M.smegmatis_MC2_155 STTPVTTSQVAPVAPVPTR--TVTETSTPAQTTVTETA-----TTTPPTT
MMAR_0618|M.marinum_M TTTTPTTTTTAPTKTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTPTT
MUL_0583|M.ulcerans_Agy99 TTTTP-TTTTAPTKTTTTTTTTTTTTTTTTTTTTTTT------TTTTPTT
Mb2287c|M.bovis_AF2122/97 DGPTTEPAPPVQAPATGGPAPPLQQPLPPPPTTTNTQPAVTTDVITPAPT
Rv2264c|M.tuberculosis_H37Rv DGPTTEPAPPVQAPATGGPAPPLQQPLPPPPTTTNTQPAVTTDVITPAPT
MAV_4816|M.avium_104 TVTITGPNDSTTVTVVPAPPPPSSEAPPPPATTTTAPPEPSTTTTTTTP-
MAB_4279|M.abscessus_ATCC_1997 SSTPADSGGGGHEGHGGHSGGGNTTVTETQTVPESPTSQDTTTTEPTTTT
MLBr_00877|M.leprae_Br4923 ETQTVTVTPLPPPSATSTAVPPSSVVPPPPTTPTTTVTTLTGPRQVTYSV
. . . .
Mflv_0270|M.gilvum_PYR-GCK TPTTTTTPSTSVSTSTS----TSTVTQTETQTETVTEPPPAPPTP-----
Mvan_0627|M.vanbaalenii_PYR-1 T-TTTTTPSTSVSTSTS----TSTVTQTETQTETVTETP-APPAP-----
TH_2748|M.thermoresistible__bu TTTTTTTESP--TTTTT----TETVTQTETETQTVTAPPDEGE-------
MSMEG_0700|M.smegmatis_MC2_155 TTTTTAPPTTSTTVETS----TSVVTSTVTETTTVPEEEGGEQP------
MMAR_0618|M.marinum_M TTTTTTAPTTTTTTTTNPMSPGAMPTFPSQLTPSIPTVINLPPGL-----
MUL_0583|M.ulcerans_Agy99 TTTTTTAPTTTTTTTTNPMSPGAMPTFPSQLTPSIPTVINLPPGL-----
Mb2287c|M.bovis_AF2122/97 TPASAPPATTQPPATTQPPATTSPSPPPIPPIPPIPEIPQLPPGIPQVPG
Rv2264c|M.tuberculosis_H37Rv TPASAPPATTQPPATTQPPATTSPSPPPIPPIPPIPEIPQLPPGIPQVPG
MAV_4816|M.avium_104 -PPSSTTTTSAAPTTTAQPSTTSAAP-TTTRVRPIPPIFQPPFGR-----
MAB_4279|M.abscessus_ATCC_1997 TTTTEPTTTTTQPTTTTTQPTTSTRPSVVVPIPGGGNIQVPVGGQ-----
MLBr_00877|M.leprae_Br4923 TGTKAPGDIISVTYVDASGRRRTQHNVYIPWSMTVTPISQSDVGSVEAFS
.. . .
Mflv_0270|M.gilvum_PYR-GCK -------------------------------
Mvan_0627|M.vanbaalenii_PYR-1 -------------------------------
TH_2748|M.thermoresistible__bu -------------------------------
MSMEG_0700|M.smegmatis_MC2_155 -------------------------------
MMAR_0618|M.marinum_M -------------------------------
MUL_0583|M.ulcerans_Agy99 -------------------------------
Mb2287c|M.bovis_AF2122/97 IGQFSAISGS---------------------
Rv2264c|M.tuberculosis_H37Rv IGQFSAISGS---------------------
MAV_4816|M.avium_104 -------------------------------
MAB_4279|M.abscessus_ATCC_1997 -------------------------------
MLBr_00877|M.leprae_Br4923 LFRVSKLNCLITTSDGTVLSSNSNDAPQTSC