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ARYGDSDDQNYYSDDEPTQLSNYGTGYGEYDQSPTEADSATPWYRKPVALVSFGAVGALLIALVVFGLAR AITGDSTSDTTTTTPLTPVTTTSAPAVVPPATVTETATATTTTEPVTTTTTTEPTTTTTTTTTTTTTPST SVSTSTSTSTVTQTETQTETVTETPAPPAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0627 | - | - | 100% (171) | hypothetical protein Mvan_0627 |
| M. vanbaalenii PYR-1 | Mvan_0621 | - | 8e-20 | 35.71% (182) | hypothetical protein Mvan_0621 |
| M. vanbaalenii PYR-1 | Mvan_0433 | - | 9e-19 | 39.61% (154) | hypothetical protein Mvan_0433 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0320 | - | 6e-13 | 36.55% (145) | hypothetical protein Mb0320 |
| M. gilvum PYR-GCK | Mflv_0270 | - | 6e-70 | 78.98% (176) | hypothetical protein Mflv_0270 |
| M. tuberculosis H37Rv | Rv0312 | - | 6e-13 | 36.55% (145) | hypothetical protein Rv0312 |
| M. leprae Br4923 | MLBr_00877 | mmpS3 | 3e-10 | 30.07% (143) | hypothetical protein MLBr_00877 |
| M. abscessus ATCC 19977 | MAB_4291 | - | 3e-18 | 35.38% (212) | hypothetical protein MAB_4291 |
| M. marinum M | MMAR_0618 | - | 2e-27 | 41.86% (172) | hypothetical protein MMAR_0618 |
| M. avium 104 | MAV_4816 | - | 3e-15 | 30.57% (193) | hypothetical protein MAV_4816 |
| M. smegmatis MC2 155 | MSMEG_0700 | - | 2e-34 | 50.86% (175) | hypothetical protein MSMEG_0700 |
| M. thermoresistible (build 8) | TH_2748 | - | 2e-40 | 52.02% (173) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0583 | - | 3e-27 | 42.44% (172) | hypothetical protein MUL_0583 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0320|M.bovis_AF2122/97 ---MYDPLGLSIGTTNLVAAGNG--GPPVTRRAVLTLYPHCAPKIGVPSQ
Rv0312|M.tuberculosis_H37Rv ---MYDPLGLSIGTTNLVAAGNG--GPPVTRRAVLTLYPHCAPKIGVPSQ
MAV_4816|M.avium_104 MRDMSEPLGLSIGVANLVAARAG--SVPVIRSSVLTLFEQRPTEVGLPDE
MAB_4291|M.abscessus_ATCC_1997 ---MANALGLSIGATQLVATPDDPQSQPVVRSSILTLHEDGPPEVGVPSQ
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mb0320|M.bovis_AF2122/97 NPNLIEPGALMSGFVERIGDAVALVSPDGSVHDPDLLLVEALDAMVLTAG
Rv0312|M.tuberculosis_H37Rv NPNLIEPGALMSGFVERIGDAVALVSPDGSVHDPDLLLVEALDAMVLTAG
MAV_4816|M.avium_104 NPNLTEPGLVLRGFVERVGDRAPLVAADGTKYLGAALTVEAVEAMARAVG
MAB_4291|M.abscessus_ATCC_1997 ------PGLTLTGFVGRVGDPVGIVAADGSVHRAEWALTEAMRVLIADAV
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mb0320|M.bovis_AF2122/97 ADASSSE---IAIAVPAHWKPGAVHALRNGLRTHVGFVRSGMAPRLVSDA
Rv0312|M.tuberculosis_H37Rv ADASSSE---IAIAVPAHWKPGAVHALRNGLRTHVGFVRSGMAPRLVSDA
MAV_4816|M.avium_104 YGAP------ITIAVPAYWSDDQFAALREEFFAQSDLAREGVAPMLVSDA
MAB_4291|M.abscessus_ATCC_1997 SSANFTAPPVLSASIPAHWSPQTVSTLRDAIDRVPAFAPGGRQLKLIPDA
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mb0320|M.bovis_AF2122/97 IAALTAVNSELGLPHGGVVGLLDFGGSATYVTLVETKSDSRTSDFQPVSA
Rv0312|M.tuberculosis_H37Rv IAALTAVNSELGLPHGSVVGLLDFGGSATYVTLVETKSDSRTSDFQPVSA
MAV_4816|M.avium_104 TAALAMLRGTPGFPSDGVIALCDFGAGGTTVTLMDGRAG-----FAPVGP
MAB_4291|M.abscessus_ATCC_1997 RAALEALAAGPGTPDRGVVVVCDLGGSGSSITLADAARG-----FQQIGQ
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mb0320|M.bovis_AF2122/97 TARYQDFSGSQIDQALLLRVIDQFGYGDDVDPASTAAVGQLG---QLREQ
Rv0312|M.tuberculosis_H37Rv TARYQDFSGSQIDQALLLRVIDQFGYGDDVDPASTAAVGQLG---QLREQ
MAV_4816|M.avium_104 SLRYTDFSGDAIDQLVLDHLLAS-----DVSTAMRGGSGRIGSQSRLLGA
MAB_4291|M.abscessus_ATCC_1997 TIRFADFSGQQIDQMLLTQVLTD----LNQDPEGTTSVGALT---RLRDQ
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 --------------------------------------------------
Mb0320|M.bovis_AF2122/97 CRAAKERLSTDVATELFAELAGCSSSIEMTREQLEDLIQDPLTGFIYAFD
Rv0312|M.tuberculosis_H37Rv CRAAKERLSTDVATELFAELAGCSSSIEMTREQLEDLIQDPLTGFIYAFD
MAV_4816|M.avium_104 CRRAKEQLSTAVAVTVAGAPG---QGAQLTRAEFEQLISTPLDRFLDWCQ
MAB_4291|M.abscessus_ATCC_1997 CRLAKERLSGDTATSVPVQLPGITTDVRLTRAELEGHLRGPLSNLINAIQ
Mvan_0627|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00877|M.leprae_Br4923 ----------------------------MSGPNPPGRENEESDSGNELSG
Mb0320|M.bovis_AF2122/97 DMLARHNASWADLAAVVTVGGGANIPLVTQRLSFHTRRPVLTASQPGCAA
Rv0312|M.tuberculosis_H37Rv DMLARHNASWADLAAVVTVGGGANIPLVTQRLSFHTRRPVLTASQPGCAA
MAV_4816|M.avium_104 EALRRNGIGNSTLRGVAIVGGGASIPLLTARLSGRFGVPVHSTAQPGLSA
MAB_4291|M.abscessus_ATCC_1997 DTVERNGIHPANITAVASVGGGASIPLVTQQLSERMRVPVITAPQPQLAA
Mvan_0627|M.vanbaalenii_PYR-1 ----------------------------MARYGDSDDQNYYSDDEPTQLS
Mflv_0270|M.gilvum_PYR-GCK ----------------------------MARYGDSDDPN-YSDDDPTQLS
TH_2748|M.thermoresistible__bu ----------------------------VAVSRPPEDPSNYSDSEPTAYS
MSMEG_0700|M.smegmatis_MC2_155 ----------------------------MANNYSDDEPTQYAHSYG---G
MMAR_0618|M.marinum_M ----------------------------MAR----HDPPDYGAGDPTAYG
MUL_0583|M.ulcerans_Agy99 ----------------------------MAR----HDPPDYGAGDPTAYG
MLBr_00877|M.leprae_Br4923 ELDPHNGVESVDELVPVPDSD------LVTASDHTSETEVYSQAYSAPEA
.
Mb0320|M.bovis_AF2122/97 AMGALLLANRGGERDSRTRTSIGLATAAAAGTSVIELPAGD---VMVIDH
Rv0312|M.tuberculosis_H37Rv AMGALLLANRGGERDSRTRTSIGLATAAAAGTSVIELPAGD---VMVIDH
MAV_4816|M.avium_104 ALGAATLGAQYASGAAPTAAAAAAVETPTEMVGAGGLDMTQ---AAWAAQ
MAB_4291|M.abscessus_ATCC_1997 ARGVALLATRPDLPPQDATAMRPVEQPPGDATMMRPVPTGTGTFAAPVAA
Mvan_0627|M.vanbaalenii_PYR-1 NYGT----------------------------------------------
Mflv_0270|M.gilvum_PYR-GCK NY------------------------------------------------
TH_2748|M.thermoresistible__bu DYTAGGSGGYVPG-------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 DYGA----------------------------------------------
MMAR_0618|M.marinum_M NYGYGD--------------------------------------------
MUL_0583|M.ulcerans_Agy99 NYGYGD--------------------------------------------
MLBr_00877|M.leprae_Br4923 EHFTAVPYVPADLR------------------------------------
Mb0320|M.bovis_AF2122/97 EALTDRELAWSQTDFPSE-APARFEG----------DSYNEGGPCWSMR-
Rv0312|M.tuberculosis_H37Rv EALTDRELAWSQTDFPSE-APARFEG----------DSYNEGGPCWSMR-
MAV_4816|M.avium_104 ATDVDDALAWSQDADTSD-EPVPYTG----------RDATGEYASEARR-
MAB_4291|M.abscessus_ATCC_1997 AANEEPELAWSQDDSAPDLAPLQETGYQSGYTVDLDDEYQGPTEATTARP
Mvan_0627|M.vanbaalenii_PYR-1 --------GYGEYDQSP---------------------------------
Mflv_0270|M.gilvum_PYR-GCK --------AYGDYEQAPP--------------------------------
TH_2748|M.thermoresistible__bu -------YGGGEYGGPPG--------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------DYGAYPPPDQ--------------------------------
MMAR_0618|M.marinum_M --------QGGGYGQQP---------------------------------
MUL_0583|M.ulcerans_Agy99 --------QRGGYGQQP---------------------------------
MLBr_00877|M.leprae_Br4923 ------LYDYDESSVYDE--------------------------------
.
Mb0320|M.bovis_AF2122/97 ---------LNAVEPPKGPAWRRIRVSQLLIGVSAVVAMTAIGGVALTLT
Rv0312|M.tuberculosis_H37Rv ---------LNAVEPPKGPAWRRIRVSQLLIGVSAVVAMTAIGGVALTLT
MAV_4816|M.avium_104 ---------FDDVAAGGLPWYKRTALVLSVAGAGAAVLIALVLAINLLLT
MAB_4291|M.abscessus_ATCC_1997 ELRFSHGPYADEDDYDDYPPLPWYRRPLVWFIAAAAVAGIAFTGMMVSLT
Mvan_0627|M.vanbaalenii_PYR-1 -----------TEADSATPWYRKPVALVSFGAVGALLIALVVFGLARAIT
Mflv_0270|M.gilvum_PYR-GCK -----------PDAEPPVPWYRKPAALVGLGALGAVLIALIVFGLAKAIT
TH_2748|M.thermoresistible__bu -----------PPEEPPVPWYRKPAALVAFGALGAVLLGLIVFALIRLTS
MSMEG_0700|M.smegmatis_MC2_155 -----------PPAPEPVPWYRKPAALVGLGALGALIVALVIYAVIQLFS
MMAR_0618|M.marinum_M -------------PPEPTPGWRKPLALAGWGVLIAVLIGLIIFGIIQLAH
MUL_0583|M.ulcerans_Agy99 -------------PPEPTPGWRKPLALAGWGVLIAVLIGLIIFGIIQLAH
MLBr_00877|M.leprae_Br4923 -----------PGAAPRWPWVVGVAAILAAISLVVSVSLLFTRTDTSKLS
* . :
Mb0320|M.bovis_AF2122/97 AIER-RPSPLPTPIVPGLAPMPPGSVVPSSRAPTPPPPPSTVAPLPSAAP
Rv0312|M.tuberculosis_H37Rv AIER-RPSPLPTPIVPGLAPMPPGSVVPSSRAPTPPPPPSTVAPLPSAAP
MAV_4816|M.avium_104 KSTQDRPTSPPS------TPAPPQTVTITG------PNDSTTVTVVPAPP
MAB_4291|M.abscessus_ATCC_1997 SSES--PAPATTTPSVNVVPSTGDAPAEPPPSPEPPPPPQTHTVTQSVQP
Mvan_0627|M.vanbaalenii_PYR-1 GDST-SDTTTTTPLTPVTTTSAPAVVPPAT------VTETA--TATTTTE
Mflv_0270|M.gilvum_PYR-GCK GDSD-SETTPTSSLTPVTTTSAPAAVPPAT------VTETASESATTTTE
TH_2748|M.thermoresistible__bu GDDA-SSETATTTTTTTTTTGAPVAPPPAT------VTQTVPPATTTPAE
MSMEG_0700|M.smegmatis_MC2_155 SDDS-SSTTSTTTSTTSTTPVTTSQVAPVA------PVPTR--TVTETST
MMAR_0618|M.marinum_M GRPTPASVTKTVTATMTTTTPTTTTTAPTK------TTTTTTTTTTTTTT
MUL_0583|M.ulcerans_Agy99 GRPTPASVTKTVTATMTTTTP-TTTTAPTK------TTTTTTTTTTTTTT
MLBr_00877|M.leprae_Br4923 TPTTGRSTPPVQDEITTVKPPPPSTETSTATETQTVTVTPLPPPSATSTA
. .
Mb0320|M.bovis_AF2122/97 APTTVAPAPPPPTQVVTTTTAPPVTTTPRPSPTTTTTTAPPSTTTTTELP
Rv0312|M.tuberculosis_H37Rv APTTVAPAPPPPTQVVTTTTAPPVTTTPRPSPTTTTTTAPPSTTTTTEPP
MAV_4816|M.avium_104 PPSSEAPPPP-----ATTTTAP-----PEPSTTTTTTTPPPSSTTTTSAA
MAB_4291|M.abscessus_ATCC_1997 PPPSPEPPPPPPP-TTTTTTTP-------PTTTTTTTTTTTTTTTTTTTP
Mvan_0627|M.vanbaalenii_PYR-1 PVTTTTTTEP-----TTTTTTTT-TTTTTPSTSVSTSTS----TSTVTQT
Mflv_0270|M.gilvum_PYR-GCK PTTTTTTTEP-----TTTTTTTTPTTTTTPSTSVSTSTS----TSTVTQT
TH_2748|M.thermoresistible__bu EPSPPPTTTQ-----TPTTTTTTTTTTTTESP--TTTTT----TETVTQT
MSMEG_0700|M.smegmatis_MC2_155 PAQTTVTETA-----TTTPPTTTTTTTAPPTTSTTVETS----TSVVTST
MMAR_0618|M.marinum_M TTTTTTTTTTTTTTTTTTTPTTTTTTTTAPTTTTTTTTNPMSPGAMPTFP
MUL_0583|M.ulcerans_Agy99 TTTTTTTTT------TTTTPTTTTTTTTAPTTTTTTTTNPMSPGAMPTFP
MLBr_00877|M.leprae_Br4923 VPPSSVVPPPPTTPTTTVTTLTGPRQVTYSVTGTKAPGDIISVTYVDASG
. ..... . . ..
Mb0320|M.bovis_AF2122/97 VTTTST-------IPTIPTTTTTVKMTTEWLHVPFLPVPIPVPIPQNPGA
Rv0312|M.tuberculosis_H37Rv VTTTST-------IPTIPTTTTTVKMTTEWLHVPFLPVPIPVPIPQNPGA
MAV_4816|M.avium_104 PTTTAQ-------PSTTSAAPTTTRVR-----------PIP-PIFQPP--
MAB_4291|M.abscessus_ATCC_1997 TTTTTQ-------PTTTTTQPTSTSRP-------AITIPGLPPIPIGPRN
Mvan_0627|M.vanbaalenii_PYR-1 ETQTET-------VTETP-APPAP--------------------------
Mflv_0270|M.gilvum_PYR-GCK ETQTET-------VTEPPPAPPTP--------------------------
TH_2748|M.thermoresistible__bu ETETQT-------VTAPPDEGE----------------------------
MSMEG_0700|M.smegmatis_MC2_155 VTETTT-------VPEEEGGEQP---------------------------
MMAR_0618|M.marinum_M SQLTPS-------IPTVINLPPGL--------------------------
MUL_0583|M.ulcerans_Agy99 SQLTPS-------IPTVINLPPGL--------------------------
MLBr_00877|M.leprae_Br4923 RRRTQHNVYIPWSMTVTPISQSDVGSVEAFSLFRVSKLNCLITTSDGTVL
* .
Mb0320|M.bovis_AF2122/97 GEPQNPFGSLGSG
Rv0312|M.tuberculosis_H37Rv GEPQNPFGSLGSG
MAV_4816|M.avium_104 ------FGR----
MAB_4291|M.abscessus_ATCC_1997 -------------
Mvan_0627|M.vanbaalenii_PYR-1 -------------
Mflv_0270|M.gilvum_PYR-GCK -------------
TH_2748|M.thermoresistible__bu -------------
MSMEG_0700|M.smegmatis_MC2_155 -------------
MMAR_0618|M.marinum_M -------------
MUL_0583|M.ulcerans_Agy99 -------------
MLBr_00877|M.leprae_Br4923 SSNSNDAPQTSC-