For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSYPEPPEDPTMFNQQYHDQEPDQPNPWYKQPAVLIALAGAGVAVVAVIAALIITRSDDKPAPAGNTSSV SSTTSSTPADSGGGGHEGHGGHSGGGNTTVTETQTVPESPTSQDTTTTEPTTTTTTTTEPTTTTTQPTTT TTQPTTSTRPSVVVPIPGGGNIQVPVGGQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4279 | - | - | 100% (169) | hypothetical protein MAB_4279 |
| M. abscessus ATCC 19977 | MAB_4291 | - | 4e-22 | 38.32% (167) | hypothetical protein MAB_4291 |
| M. abscessus ATCC 19977 | MAB_4278 | - | 4e-10 | 27.16% (162) | hypothetical protein MAB_4278 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2287c | - | 7e-12 | 35.63% (174) | hypothetical protein Mb2287c |
| M. gilvum PYR-GCK | Mflv_0276 | - | 5e-18 | 39.57% (139) | hypothetical protein Mflv_0276 |
| M. tuberculosis H37Rv | Rv2264c | - | 7e-12 | 35.63% (174) | hypothetical protein Rv2264c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0618 | - | 5e-19 | 37.04% (162) | hypothetical protein MMAR_0618 |
| M. avium 104 | MAV_4816 | - | 3e-15 | 40.27% (149) | hypothetical protein MAV_4816 |
| M. smegmatis MC2 155 | MSMEG_0700 | - | 2e-19 | 35.00% (160) | hypothetical protein MSMEG_0700 |
| M. thermoresistible (build 8) | TH_2748 | - | 1e-17 | 34.91% (169) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0583 | - | 3e-18 | 34.44% (180) | hypothetical protein MUL_0583 |
| M. vanbaalenii PYR-1 | Mvan_0621 | - | 5e-18 | 39.86% (138) | hypothetical protein Mvan_0621 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2287c|M.bovis_AF2122/97 MATGARPALGLSIGVTNLAAVAADHS-ITRKPVLTLYRQRPPEVGVPSEN
Rv2264c|M.tuberculosis_H37Rv MATGARPALGLSIGVTNLAAVAADHS-ITRKPVLTLYRQRPPEVGVPSEN
MAV_4816|M.avium_104 -MRDMSEPLGLSIGVANLVAARAGSVPVIRSSVLTLFEQRPTEVGLPDEN
Mflv_0276|M.gilvum_PYR-GCK ----MTEPLGLSIGTTNLVAARVGRPPVTRRAILTLVAGQAPQVGTPEEN
Mvan_0621|M.vanbaalenii_PYR-1 ----MTEPLGLSIGMTNLVAARVGRPPVTRRSILNLYTDRAPEVGAPSEI
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 PRLDEPGLVITDFVDRVGDSVGIVAADGSVYRSEALVADALLALAYTATG
Rv2264c|M.tuberculosis_H37Rv PRLDEPGLVITDFVDRVGDSVGIVAADGSVYRSEALVADALLALAYTATG
MAV_4816|M.avium_104 PNLTEPGLVLRGFVERVGDRAPLVAADGTKYLGAALTVEAVEAMARAVGY
Mflv_0276|M.gilvum_PYR-GCK AGNNPSGVVLTGFVDRVGDPVPLIAEDGSAHRGEQVLAAALDAMARLVDG
Mvan_0621|M.vanbaalenii_PYR-1 PGFSQPRLVLSGFVERVGDPVPLVAADGSAHRGEQTLAQALDAMAGLVDG
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 GRALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLSLLPD
Rv2264c|M.tuberculosis_H37Rv GRALPGSVTVTYPAHWGPAAVAALDSALRRASEWSHGTSSTAQPLSLLPD
MAV_4816|M.avium_104 G----APITIAVPAYWSDDQFAALREEFFAQSDLAR----EGVAPMLVSD
Mflv_0276|M.gilvum_PYR-GCK G----SPVAIAVPSHWGPGTVGALRGALRTVPSLSP----GGVPATLIPD
Mvan_0621|M.vanbaalenii_PYR-1 G----APVAIAVPAHWGPGTVGALRGALRAAPRLSP----NGIPPALIPD
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 AAAALYAIRADPGIPARGIVAVCDFGGSGTGITLVDAADEYRPVAATVRH
Rv2264c|M.tuberculosis_H37Rv AAAALYAIRADPGIPARGIVAVCDFGGSGTGITLVDAADEYRPVAATVRH
MAV_4816|M.avium_104 ATAALAMLRGTPGFPSDGVIALCDFGAGGTTVTLMDGRAGFAPVGPSLRY
Mflv_0276|M.gilvum_PYR-GCK STAALASLRVSPGLPGSGVVVLVDLGGSGSSVTLADAGANLVVVGQTVRY
Mvan_0621|M.vanbaalenii_PYR-1 ATAALAALRVTPGLPSQGVVVLVDLGGSGSSITLADAGSGAATIGQTVRY
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 QAFSGDLIDQSLLSYVMSELPGTGAFDP---AGTSAIGSLTKLRIECRKA
Rv2264c|M.tuberculosis_H37Rv QAFSGDLIDQSLLSYVMSELPGTGAFDP---AGTSAIGSLTKLRIECRKA
MAV_4816|M.avium_104 TDFSGDAIDQLVLDHLLASDVSTAMRG-----GSGRIGSQSRLLGACRRA
Mflv_0276|M.gilvum_PYR-GCK PEFSGDGIDRALLDHVLAGVSDTGQAD---TAGTAAVGPLMRLREECRAA
Mvan_0621|M.vanbaalenii_PYR-1 PDFSGEAIDQALLGHVLTGIADADTADPAGTAGTAAVGPLSRLRDECRAA
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 KERLSSSTVTTLTDALG---GDIRLTRNELEDTIRDSLDSVGRALEQTLA
Rv2264c|M.tuberculosis_H37Rv KERLSSSTVTTLTDALG---GDIRLTRNELEDTIRDSLDSVGRALEQTLA
MAV_4816|M.avium_104 KEQLSTAVAVTVAGAPG---QGAQLTRAEFEQLISTPLDRFLDWCQEALR
Mflv_0276|M.gilvum_PYR-GCK KERLSSETATAVPVDLPGFRSEVRVTRPELEQMIAGPLDGLLSLIDDTLT
Mvan_0621|M.vanbaalenii_PYR-1 KERLSGETATAVPVELPGFSSDVRVTRPELEQLISEPLTGLLSAIDDVLQ
MMAR_0618|M.marinum_M --------------------------------------------------
MUL_0583|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
TH_2748|M.thermoresistible__bu --------------------------------------------------
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 RSGIRTAELVAIVSVGGGANIPAVTTTLSGRFCVPVVRTPRPQLTAAFGG
Rv2264c|M.tuberculosis_H37Rv RSGIRTAELVAIVSVGGGANIPAVTTTLSGRFCVPVVRTPRPQLTAAFGG
MAV_4816|M.avium_104 RNGIGNSTLRGVAIVGGGASIPLLTARLSGRFGVPVHSTAQPGLSAALGA
Mflv_0276|M.gilvum_PYR-GCK RNGVATENISAIATVGGGAAIPLVTQRLSERLRAPVVTTPQALLNIGAGA
Mvan_0621|M.vanbaalenii_PYR-1 RNGIAAGDVSAVATVGGGAAIPLVTQRLSERLRAPVVTTPEPALNVAAGA
MMAR_0618|M.marinum_M -------------------------------------------------M
MUL_0583|M.ulcerans_Agy99 -------------------------------------------------M
MSMEG_0700|M.smegmatis_MC2_155 --------------------------------------------------
TH_2748|M.thermoresistible__bu ---------------------------------------------VAVSR
MAB_4279|M.abscessus_ATCC_1997 --------------------------------------------------
Mb2287c|M.bovis_AF2122/97 ALWAARRPGDTSATVLTA----VTSATATAPADAP------------ASV
Rv2264c|M.tuberculosis_H37Rv ALWAARRPGDTSATVLTA----VTSATATAPADAP------------ASV
MAV_4816|M.avium_104 ATLGAQYASGAAPTAAAA----AAVETPTEMVGAGGLDMTQAAWAAQATD
Mflv_0276|M.gilvum_PYR-GCK ALIANQTLDADAPTGMAPTGMAAAADVPTAMGPAVDAPTALG--PAAPPV
Mvan_0621|M.vanbaalenii_PYR-1 ALVANQSLATDAPTGMAP-----AADAPTAMGHAAWAAGAAG--LAATES
MMAR_0618|M.marinum_M ARHDPPDYGAGDPTAYGN--------------------------------
MUL_0583|M.ulcerans_Agy99 ARHDPPDYGAGDPTAYGN--------------------------------
MSMEG_0700|M.smegmatis_MC2_155 ---MANNYSDDEPTQYAH--------------------------------
TH_2748|M.thermoresistible__bu PPEDPSNYSDSEPTAYSD--------------------------------
MAB_4279|M.abscessus_ATCC_1997 ---MSYPEPPEDPTMFNQ--------------------------------
.*
Mb2287c|M.bovis_AF2122/97 LQP--------ALAWSEADE-------------DSHIGPAPGYTAARPSL
Rv2264c|M.tuberculosis_H37Rv LQP--------ALAWSEADE-------------DSHIGPAPGYTAARPSL
MAV_4816|M.avium_104 VDD--------ALAWSQDAD-------------TSDE-PVP-YTGRDATG
Mflv_0276|M.gilvum_PYR-GCK AGG--------ALAWSQDDDGVQDPLPYTGADYTSPAGYGDAATGARPPV
Mvan_0621|M.vanbaalenii_PYR-1 AGDGASSATFRALAWSQDDDAAGDPLPYTGEDYTVAGGYADPGTAARPSV
MMAR_0618|M.marinum_M -------------------------------------YGYGDQGG---GY
MUL_0583|M.ulcerans_Agy99 -------------------------------------YGYGDQRG---GY
MSMEG_0700|M.smegmatis_MC2_155 -------------------------------------SYGGDYG---ADY
TH_2748|M.thermoresistible__bu -------------------------------------YTAGGSGGYVPGY
MAB_4279|M.abscessus_ATCC_1997 -------------------------------------QYHDQEPD-----
Mb2287c|M.bovis_AF2122/97 SFDHDAHAEPEPKSPPIPWYRLPAVIITGTTVAVLLVGAAVAIGLSTGDQ
Rv2264c|M.tuberculosis_H37Rv SFDHDAHAEPEPKSPPIPWYRLPAVIITGTTVAVLLVGAAVAIGLSTGDQ
MAV_4816|M.avium_104 EYASEARRFDDVAAGGLPWYKRTALVLS-----VAGAGAAVLIALVLAIN
Mflv_0276|M.gilvum_PYR-GCK AFAPGDDGYSDDLPP-LPWYKRPPVLFGLAAAAALLAVGGLAVTLTSSEG
Mvan_0621|M.vanbaalenii_PYR-1 DFAGQDDTYTDELAP-LPWYKRPPVLFGVAAAAALLAAGGLAVTLTGSQG
MMAR_0618|M.marinum_M G-------QQPP-PEPTPGWRKPLALAGWGVLIAVLIGLIIFGIIQLAHG
MUL_0583|M.ulcerans_Agy99 G-------QQPP-PEPTPGWRKPLALAGWGVLIAVLIGLIIFGIIQLAHG
MSMEG_0700|M.smegmatis_MC2_155 G--AYPPPDQPPAPEPVPWYRKPAALVGLGALGALIVALVIYAVIQLFSS
TH_2748|M.thermoresistible__bu GGGEYGGPPGPPEEPPVPWYRKPAALVAFGALGAVLLGLIVFALIRLTSG
MAB_4279|M.abscessus_ATCC_1997 --------------QPNPWYKQPAVLIALAGAGVAVVAVIAALIITRSDD
* :: . : . :
Mb2287c|M.bovis_AF2122/97 PTAPGTPQRPGVTTTAAPPPSPAPASDGPTTEPAPPVQAPATGGPAPPLQ
Rv2264c|M.tuberculosis_H37Rv PTAPGTPQRPGVTTTAAPPPSPAPASDGPTTEPAPPVQAPATGGPAPPLQ
MAV_4816|M.avium_104 LLLTKSTQ----DRPTSPPSTPAPPQTVTITGPNDSTTVTVVPAPPPPSS
Mflv_0276|M.gilvum_PYR-GCK -STTVTETASTTAPSDTTPVELPPPVTTVTIGPDGVATTTVSQPPPPPPS
Mvan_0621|M.vanbaalenii_PYR-1 DSGTVTETAS--VPTETPPAELPPPVTTVTVGADGIATTTVSQPPPPPPS
MMAR_0618|M.marinum_M RPTPASVTKTVTATMTTTTPTTTTTAPTKTTTTTTTTTTTTTTTTT----
MUL_0583|M.ulcerans_Agy99 RPTPASVTKTVTATMTTTTP-TTTTAPTKTTTTTTTTTTTTTTTTT----
MSMEG_0700|M.smegmatis_MC2_155 DDS-SSTTSTTTSTTSTTPVTTSQVAPVAPVPTRTVT-ETSTPAQT----
TH_2748|M.thermoresistible__bu DDA-SSETATTTTTTTTT--TGAPVAPPPATVTQTVPPATTTPAEEPSPP
MAB_4279|M.abscessus_ATCC_1997 KPAPAGNTSSVSSTTSSTPADSGGGGHEGHGGHSGGGNTTVTETQTVPES
:. .
Mb2287c|M.bovis_AF2122/97 QPLPPPPTT-----TNTQPAVTTDVITPAPTTPASAPPATTQPPATTQPP
Rv2264c|M.tuberculosis_H37Rv QPLPPPPTT-----TNTQPAVTTDVITPAPTTPASAPPATTQPPATTQPP
MAV_4816|M.avium_104 EAPPPPATT-----TTAPPEPSTTTTTTTP--PPSSTTTTSAAPTTTAQP
Mflv_0276|M.gilvum_PYR-GCK STSSTTTTTPSSSTTTTTTTTTTTTTTTTNTAPTTTTTRTTTAPPTTTPP
Mvan_0621|M.vanbaalenii_PYR-1 SSTTTPTTASTTSPTTTTTTTTTTTTTTT-----TTTTRTTTTQPTTTAP
MMAR_0618|M.marinum_M -TTTTTTTT-TTTTTTTTPTTTTTTTTAPTTTTTTTTNPMSPGAMPTFPS
MUL_0583|M.ulcerans_Agy99 -TTTTTT-------TTTTPTTTTTTTTAPTTTTTTTTNPMSPGAMPTFPS
MSMEG_0700|M.smegmatis_MC2_155 -TVTETA-------TTTPPTTTTTTTAPPTTSTTVETSTS----VVTSTV
TH_2748|M.thermoresistible__bu PTTTQTP-------TTTTTTTTTTTTESPTTTTTTETVT------QTETE
MAB_4279|M.abscessus_ATCC_1997 PTSQDTT--------TTEPTTTTTTTTEPTTTTTQPTTTTT---QPTTST
. .. .: . :* . . . *
Mb2287c|M.bovis_AF2122/97 ATTSPSPPPIPPIPPIPEIPQLPPGIPQVPGIGQFSAISGS
Rv2264c|M.tuberculosis_H37Rv ATTSPSPPPIPPIPPIPEIPQLPPGIPQVPGIGQFSAISGS
MAV_4816|M.avium_104 STTSAAP-TTTRVRPIPPIFQPPFGR---------------
Mflv_0276|M.gilvum_PYR-GCK PTTTQAPPPPTTEEPPP-TVDPPDPIVTT-VIPDGGA----
Mvan_0621|M.vanbaalenii_PYR-1 PTTTQPPPPTTTAAPPPTTVDPPDPVTTTVIIPEDGA----
MMAR_0618|M.marinum_M QLTPSIPTVINLPPGL-------------------------
MUL_0583|M.ulcerans_Agy99 QLTPSIPTVINLPPGL-------------------------
MSMEG_0700|M.smegmatis_MC2_155 TETTTVPEEEGGEQP--------------------------
TH_2748|M.thermoresistible__bu TQTVTAPPDEGE-----------------------------
MAB_4279|M.abscessus_ATCC_1997 RPSVVVPIPGGGNIQVPVGGQ--------------------
: *