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MRIAVAGAGAVGRSVAQELVGYGHKVLLIEKEFDRYQPATVPGAEWLWADACEIASLEEAEMQICDVAIA ATGDDKANLAMALLAKTEFGIDRVVARINDARNEWLFTEAWGIDVAVSTPLALVAAVEGAIDVGHLVRLM ALGRDSRGDLGQKATNVAKFTLPDGGPLVGRRVRDLEMPTDSALVTLMRGIHLIVPGPDEALRAGDELLF VFASGVEERIRAMVQGTRRLE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0161 | - | - | 100% (231) | TrkA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3928 | - | 1e-59 | 51.79% (224) | TrkA domain-containing protein |
| M. gilvum PYR-GCK | Mflv_3927 | - | 1e-11 | 26.61% (218) | TrkA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2711 | ceoC | 2e-60 | 51.34% (224) | TRK system potassium uptake protein CEOC |
| M. tuberculosis H37Rv | Rv2692 | ceoC | 2e-60 | 50.89% (224) | TRK system potassium uptake protein CEOC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4718 | - | 6e-76 | 61.67% (227) | putative potassium uptake protein |
| M. marinum M | MMAR_2584 | ceoC1 | 6e-73 | 60.79% (227) | TRK system potassium uptake protein CeoC1 |
| M. avium 104 | MAV_3583 | - | 3e-62 | 53.10% (226) | TrkB protein |
| M. smegmatis MC2 155 | MSMEG_2769 | - | 2e-60 | 52.17% (230) | TrkB protein |
| M. thermoresistible (build 8) | TH_2213 | trkB | 1e-64 | 54.02% (224) | TRK SYSTEM POTASSIUM UPTAKE PROTEIN CEOC |
| M. ulcerans Agy99 | MUL_3176 | ceoC1 | 1e-72 | 60.35% (227) | TRK system potassium uptake protein CeoC1 |
| M. vanbaalenii PYR-1 | Mvan_0745 | - | 1e-112 | 86.15% (231) | TrkA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2769|M.smegmatis_MC2_155 -----MKVAIAGAGAVGRSIARELLESNHEVTLLERNLDHIDVDAIPAAH
TH_2213|M.thermoresistible__bu -----MKVAIAGAGAVGRSIARELLAS-HEVLLVERNPDHFEPDVIPGAE
Mb2711|M.bovis_AF2122/97 -----MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAH
Rv2692|M.tuberculosis_H37Rv -----MKVAVAGAGAVGRSVTRELVENGHDITLIERNPDHLDAAAIPEAH
MAV_3583|M.avium_104 -----MKVAVAGAGAVGRSVTRELLANGHDVTLIERNPDHVDVDAIPAAH
Mflv_0161|M.gilvum_PYR-GCK -----MRIAVAGAGAVGRSVAQELVGYGHKVLLIEKEFDRYQPATVPGAE
Mvan_0745|M.vanbaalenii_PYR-1 -----MRIAVAGAGAVGRSVAQELVGYGHKVLVIEKEFDRYQPATVPGAE
MMAR_2584|M.marinum_M -----MRVGIAGAGKVGRSVAQELLDGGHKVLLIERERDDFEPNSVPAAD
MUL_3176|M.ulcerans_Agy99 -----MRVGIAGAGKVGRSVAQELLDGGHKVLLIERERDDFEPNSVPAAD
MAB_4718|M.abscessus_ATCC_1997 MVERKMRVAIAGAGKVGRSVARELVDYGHKILLIERERSNFEPQSVAGAD
*::.:**** ****:::**: *.: ::*:: . : :. *.
MSMEG_2769|M.smegmatis_MC2_155 WRLGDACEITMLESVRLEEFDVVIAATGDDKVNVVVSLLAKTEFAVPRVV
TH_2213|M.thermoresistible__bu WRLGDACELSLLESVGLEQYDVVIAATGDDKANVVVSLLAKTEFGVSRVV
Mb2711|M.bovis_AF2122/97 WRLGDACELSLLESIHLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVV
Rv2692|M.tuberculosis_H37Rv WRLGDACELSLLESIHLEEFDVVVAATGDDKVNVVLSLLAKTEFAVPRVV
MAV_3583|M.avium_104 WRLGDACELSLLESVQLQEFDVVVAATGDDKANVVLSLLAKTEFAVPRVV
Mflv_0161|M.gilvum_PYR-GCK WLWADACEIASLEEAEMQICDVAIAATGDDKANLAMALLAKTEFGIDRVV
Mvan_0745|M.vanbaalenii_PYR-1 WLWADACEIASLEEAEFQICDVAIAATGDDKANLAMALLAKTEFGIGRVV
MMAR_2584|M.marinum_M WLHGDACELSTLQEAGAQTCDVVIAATGDDKANLVVGLLAKTEFGVPRVV
MUL_3176|M.ulcerans_Agy99 WLHGDACELSTLQEAGAQTCDVVIAATGEDKANLVVGLLAKTEFGVPRVV
MAB_4718|M.abscessus_ATCC_1997 WLNADACELDTLEEAGTETCDVVVAATGDDKANLVVGLLAKSEFGVPRVV
* .****: *:. : **.:****:**.*:.:.****:**.: ***
MSMEG_2769|M.smegmatis_MC2_155 ARVNDPRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEF-RK
TH_2213|M.thermoresistible__bu ARVNDPRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEF-RQ
Mb2711|M.bovis_AF2122/97 ARVNDPRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTVGDLVRLMEF-RT
Rv2692|M.tuberculosis_H37Rv ARVNDPRNEWLFNDAWGVDVAVSTPRMLASLIEEAVTIGDLVRLMEF-RT
MAV_3583|M.avium_104 ARVNDPRNEWLFTDAWGVDVAVSTPRMLASLIEEAVAVGDLVRLMEF-RK
Mflv_0161|M.gilvum_PYR-GCK ARINDARNEWLFTEAWGIDVAVSTPLALVAAVEGAIDVGHLVRLMALGRD
Mvan_0745|M.vanbaalenii_PYR-1 ARINEASNEWLFTEAWGVDVAVSTPLAIVAAIEGAIDVGHLIRLMALGRE
MMAR_2584|M.marinum_M ARINDLRNEWLFGQSWGIDVAVSTPGAMVAGIEGAIDVGHLVRMMGL-RE
MUL_3176|M.ulcerans_Agy99 ARINDLRNEWLFGQSWGIDVAVSTPGAMVAGIEGAIDVGHLVRMMGL-RE
MAB_4718|M.abscessus_ATCC_1997 ARINDIRNQWLFGQAWGVDVAVSTPGAMVAGIEGAIDIGHLVRLMGL-RE
**:*: *:*** : **:******* :.: :* *: :*.*:*:* : *
MSMEG_2769|M.smegmatis_MC2_155 GQANL-------VEITLPDDTPWGGKPVKRLELPRDAALVTILRGARVIV
TH_2213|M.thermoresistible__bu GQANL-------VEITLPDDTPWGGRPVRRLDLPRDAAMVAILRGPRVIV
Mb2711|M.bovis_AF2122/97 GQANL-------VEITLPDNTPWGGKPVRKLQLPRDAALVTILRGPRVIV
Rv2692|M.tuberculosis_H37Rv GQANL-------VEITLPDNTPWGGKPVRKLQLPRDAALVTILRGPRVIV
MAV_3583|M.avium_104 GQANL-------VEITLPDDTPWGGKPVRRLQLPRDAALVTILRGPRVIV
Mflv_0161|M.gilvum_PYR-GCK SRGDLGQKATNVAKFTLPDGGPLVGRRVRDLEMPTDSALVTLMRGIHLIV
Mvan_0745|M.vanbaalenii_PYR-1 SRGDLGQRATNVAKFTLPEDSPLVAQQVRDLAMPRDSALVTVVRGNRLII
MMAR_2584|M.marinum_M GRAAL-------TKLTLPSDNPLVGKRVSELELPSNTALVSVLRGDAVRV
MUL_3176|M.ulcerans_Agy99 GRAAL-------TKLTLPSDNPLVGKRVSELELPSNTALVSVLRGDAVRV
MAB_4718|M.abscessus_ATCC_1997 GRADL-------TKLTLPQDNPLVGRRVADLELPPNTALVTVVRHGTVVT
.:. * .::***.. * .: * * :* ::*:*:::* :
MSMEG_2769|M.smegmatis_MC2_155 PEADEPLEGGDELLFVATTEVEDELLEVLLRPTRR---------------
TH_2213|M.thermoresistible__bu PEPDEPLEGGDELLFVAVAEVEDELREIILRPPRQ---------------
Mb2711|M.bovis_AF2122/97 PEADEPLEGGDELLFVAVTEAEEELSRLLLPSM-----------------
Rv2692|M.tuberculosis_H37Rv PEADEPLEGGDELLFVAVTEAEEELSRLLLPSM-----------------
MAV_3583|M.avium_104 PEEDEPLEGGDELLFVAVAEAEEELQKLLLG-------------------
Mflv_0161|M.gilvum_PYR-GCK PGPDEALRAGDELLFVFASGVEERIRAMVQGTRRLE--------------
Mvan_0745|M.vanbaalenii_PYR-1 PEPHDVLRAGDEMLFVAASGVEEHIEAMVQGTRRLE--------------
MMAR_2584|M.marinum_M PQPDDTLEPGDELLFIADSFLERSVWAAVYSTMPSRAPLGLAGRPSGLRN
MUL_3176|M.ulcerans_Agy99 PQPDDTLEPGDELLFIADSFLERSVWAAVYSTMPSRAPVGLAGRPSGLRN
MAB_4718|M.abscessus_ATCC_1997 PSPGDLLEAGDEMLFIANSDVEYAIRAAIHGTGVLPES------------
* : *. ***:**: : * : :
MSMEG_2769|M.smegmatis_MC2_155 ---
TH_2213|M.thermoresistible__bu ---
Mb2711|M.bovis_AF2122/97 ---
Rv2692|M.tuberculosis_H37Rv ---
MAV_3583|M.avium_104 ---
Mflv_0161|M.gilvum_PYR-GCK ---
Mvan_0745|M.vanbaalenii_PYR-1 ---
MMAR_2584|M.marinum_M RRG
MUL_3176|M.ulcerans_Agy99 RRG
MAB_4718|M.abscessus_ATCC_1997 ---