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ILLGVAISIAVVVAVGFFVSTRIKGDSSNFLVGGRMLPFWLVGGALMGAAVDTNATLGNTDLAYEFGFWA GACLPLGLALCLLITGIFFAKPMNRMGLTSFPDYYRLRFGRSVEIGASILLAVAFCMLVAGNLVAGGLLF NYFLGMPHWLGVVLIAAIAVAYTGTGGLIADAYTAIIQMGLILAGAIGLFFWMTTTHGLDIADGTGPFAL GQLSDPAQGAVINWATLIALGIGDIVAIDFMARVFSAKSPEAARRACFTAAAGTAAICVPFGLVVLAAHS FLPAELDGPVLFVLLDQYAPAGLTVLVLCGLMGASMSTANGAILAISNVCVRNLGGVRRVHEPGRKDPLL RAARVAMAPMTLFSILFAIYVQQTGILLTLAFDLMLACLIVPFILGLVWRRGTTTAALAAIAVGFTVRIG LFVLTPTMFGVENTILYIPNDLVSASFDGWPTFIAFAAGLATYVAVALATKPAHMRGLDIQVARDLDDIL DDADRFEKEPEPVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0093 | - | - | 100% (505) | Na+/solute symporter |
| M. gilvum PYR-GCK | Mflv_0248 | - | 5e-11 | 25.05% (459) | Na+/solute symporter |
| M. gilvum PYR-GCK | Mflv_2141 | - | 4e-10 | 27.57% (185) | Na+/solute symporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4639 | - | 9e-26 | 26.06% (518) | putative Na+/solute symporter |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4571 | - | 9e-05 | 23.61% (415) | metal ion transporter, NRAMP family protein |
| M. smegmatis MC2 155 | MSMEG_4462 | - | 1e-40 | 28.36% (476) | sodium:solute symporter |
| M. thermoresistible (build 8) | TH_3825 | - | 1e-121 | 48.46% (454) | PUTATIVE putative Na+/solute symporter |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0815 | - | 0.0 | 88.05% (502) | Na+/solute symporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0093|M.gilvum_PYR-GCK -----------MILLGVAISIAVVVAVGFFVSTRIKGDSSNFLVGGRMLP
Mvan_0815|M.vanbaalenii_PYR-1 -----------MILLGVAISIAVVVAVGFFVSRRIEGDSSNFLVGGRMLP
TH_3825|M.thermoresistible__bu -----------MILTGVAVFLLVLTVSGVVSARRVRGDCANYLVAGRALP
MSMEG_4462|M.smegmatis_MC2_155 -------MGKPLDIAIVAVYLIAMLAFGFWGKTRTK-DSADFLVAGRRLG
MAB_4639|M.abscessus_ATCC_1997 MTGSLRLDAGPVDYVLIAIYFVFVLGIGLLARRGVS-SSIDFFLSGRSLP
MAV_4571|M.avium_104 ----------------MTETTTQPVADAVADRPSVSLRTRGRWLRWGLLS
:: .. . : *
Mflv_0093|M.gilvum_PYR-GCK FWLVGGALMGAAVDTNATLGNTDLAYEFGFWAGACLPLGLALCLLITGIF
Mvan_0815|M.vanbaalenii_PYR-1 FWLVGGALMGAAVDTNATLGNTDLAFGFGFWAGATLPLGLALCLTITGIF
TH_3825|M.thermoresistible__bu AVLVAAVLIAQPVDSNATIGNADLSAAFGFWAGAALPIGLALCLLLMGLF
MSMEG_4462|M.smegmatis_MC2_155 PTLYTGTMAAVVLGGASTVGGVGLGYKWG-LSGMWLVVAIAVGLLALSLL
MAB_4639|M.abscessus_ATCC_1997 AWVTGLAFVSANLGAVEIMGMSANGAQFGMVGMHYFWIGAVPAILFLGIV
MAV_4571|M.avium_104 VWGPGLVVMLADTDAGSLITASQSGAQWG--YRMVLPQLILMPVLYVVQE
.. . : . :* : :
Mflv_0093|M.gilvum_PYR-GCK FAKPMNRMGLTSFPDYYRLRFGRSVEIGASILLAVAFCMLVAGNLVAGGL
Mvan_0815|M.vanbaalenii_PYR-1 FAKPMNRMGLTSFPDYYRLRFGRSVEVGASLLLVVAFCMLVAGNLVAGGL
TH_3825|M.thermoresistible__bu FARRLRAAQVVTLPEYFGNRFGRGVEVASSALTVGSFAILLAGNLVAIGF
MSMEG_4462|M.smegmatis_MC2_155 FAGRIQRLKVYTVAQMLSLRYGVDATSASGVVMVTYTLMLSVTSTIAYAT
MAB_4639|M.abscessus_ATCC_1997 MMPFFYGSQVRSVPEYMLHRFGVGAHLVNATGFAVAQVLIAGVNLYLLGT
MAV_4571|M.avium_104 MTVRLGIVTGRGHGSLIRERFGRGWAWLSAFTLFASAIGALLTEFAGVAG
: : . *:* . . . .
Mflv_0093|M.gilvum_PYR-GCK LFNYFLGMPHWLGVVLIAAIAVAYTGTGGLIADAYTAIIQMGLILAGAIG
Mvan_0815|M.vanbaalenii_PYR-1 LFNYFLGMPYWLGVVLIAAIAVAYTGTGGLIADAYTAIIQMALILAGAIG
TH_3825|M.thermoresistible__bu LLERFLGVSYTIGILVTVPLALLYTITGGMFASVYTGVAQVVVNIVGVFA
MSMEG_4462|M.smegmatis_MC2_155 VFNVLFGTGRTVSVLIGGAVVMLYSSIGGMWSITLTDMVQFILKTIGVFF
MAB_4639|M.abscessus_ATCC_1997 IVNVLLGWPLWVSVIAAAAIVLCYITLGGLSAAIYNEVLQFFVIVAALLP
MAV_4571|M.avium_104 VG-ELFGVSRWVSIPVATIALLALALTGSYRRVERIGLAVGAAELAFLVA
: ::* :.: : *. : .
Mflv_0093|M.gilvum_PYR-GCK LFFWMTTTHG--LDIADG-TGPFALGQLSDPAQG---AVINWATLIALGI
Mvan_0815|M.vanbaalenii_PYR-1 LFVWMSSTHG--IDIAEG-TGPFAFGQLSDPAQG---AVINWATLIALGI
TH_3825|M.thermoresistible__bu LVVWVAATHG--FTAPDG-MGAGALSQLTSSESG---AVINWATIIALGL
MSMEG_4462|M.smegmatis_MC2_155 LLLPFTWNRA--GGLDGI-RERAGDAVFSLTAIG---TETIITFFVVYSF
MAB_4639|M.abscessus_ATCC_1997 LTIVGLHQVGGWQGLQDK-VSAGQMSSWPGNELSGFSDNLLSVIGIVFGL
MAV_4571|M.avium_104 MVMARPDPGALAHGLTSMPLGDSSYLLLIAANVG----AVIMPWMIFYQQ
: . . . :
Mflv_0093|M.gilvum_PYR-GCK GDIVAIDFMAR-------VFSAKSPEAARRACFTAAAGTAAICVPFGLVV
Mvan_0815|M.vanbaalenii_PYR-1 GDVVAIDFMAR-------VFSAKSPDAARKACFSAATGTVAICVPFGLVV
TH_3825|M.thermoresistible__bu GNLVAIDLMQR-------VFSARDPGAAQRACFAAAGGILLLCLPLSFVA
MSMEG_4462|M.smegmatis_MC2_155 GMLIGQDIWQR-------VFTARSPQVAKWGGTTAALYCVAYGVAGALIG
MAB_4639|M.abscessus_ATCC_1997 GFVLSFGYWTTNFVEVQRALASESLSAARRTPIIGAFPKMFIPFIVVIPG
MAV_4571|M.avium_104 GAVVDKHLSES---------------TIRQARYDTAFGAVLTQLIMIAVV
* :: . : * .
Mflv_0093|M.gilvum_PYR-GCK LAAHSFLP-AELDGP-------------VLFVLLDQYAPAGLTVLVLCGL
Mvan_0815|M.vanbaalenii_PYR-1 LAAHSFMP-AELDGP-------------VLFVLLDQYAPAGLTVLVLCGL
TH_3825|M.thermoresistible__bu LAAVGIVGDSAGDGP-------------ILYALLGEYAPAWLAIIVISGL
MSMEG_4462|M.smegmatis_MC2_155 AAASTFLPDVEAKDD-------------VYAQIAESILPVGISGLVLAAA
MAB_4639|M.abscessus_ATCC_1997 MICAVLVPQMVAYKAGQPTSDPNLTYSNSLLYLMKEVLPNGVLGVAITGL
MAV_4571|M.avium_104 ITMASTIGRHGDGAP--------------LETVGQIAQSLTPYLGHVGGT
: : . : .
Mflv_0093|M.gilvum_PYR-GCK MGASMSTANGAILAISNVCVRNLGGVRR--VHEPGRKDP-----LLRAAR
Mvan_0815|M.vanbaalenii_PYR-1 VGASMSTANGAILAISNVCVRNLGGVRR--VHEPGKRDP-----LLRATR
TH_3825|M.thermoresistible__bu LAATLTTVSGILLSTASVLVRNVLRIDTGVLAPPAAMTPR----MLRATR
MSMEG_4462|M.smegmatis_MC2_155 VAAMMSTASGALIATATVARTDVRPLLLRLVGRRTETVTDDPSLEVHADR
MAB_4639|M.abscessus_ATCC_1997 LASFMAGMAANVSAFNTVFSYDLWQRYIRKDRPDGYYLR-----IGRIAT
MAV_4571|M.avium_104 VLFGLGMLGAALVAAIVASLAGAWGLAEVFGWKHTLNQR-----PNRATA
: : . : : . . :
Mflv_0093|M.gilvum_PYR-GCK VAMAPMTLFSILFAIYVQQTGILLTLAFDLMLA-CLIVPFILGLVWRRGT
Mvan_0815|M.vanbaalenii_PYR-1 IAMVPMTLFSIAFAIYVKQTGILLTLAFDLLLA-CLAVPFILGLYWRRGT
TH_3825|M.thermoresistible__bu WATLPMAALAAVVALRVPQTGILLTLAFDLLLA-SLVVPFILGLYWSRGG
MSMEG_4462|M.smegmatis_MC2_155 RYVVVLGIVVIVIAALLNDVVGALTIAYDILVG-GLLVPILGGFVWKRAT
MAB_4639|M.abscessus_ATCC_1997 VGATVIAIGTAFIAANYNNVMNYLQTLFAFFNA-PLFATFILGMFWRRMT
MAV_4571|M.avium_104 KFYLTYSLAHIVGAVLVLASVDLVNLAVDVEIMNALLLPIVLGLLLALEA
* : . * .:: *:
Mflv_0093|M.gilvum_PYR-GCK TTAALAAIAVGFTVRIGLFVLTPT----MFGVENTILYIPNDLVSASFDG
Mvan_0815|M.vanbaalenii_PYR-1 VKAAMAAMVVGFVVRVGLFVLTPT----IYGVDNTILYIPNTLVGAAFDG
TH_3825|M.thermoresistible__bu AAAAAAAVVVGIGVRLTYFVLAPT----IYGVDNTLLYLPNDWVSAXXRG
MSMEG_4462|M.smegmatis_MC2_155 GAGALVAMGVGTVVTLGTMAIVGD----VLANDPIYWGLATSLVAYVAVS
MAB_4639|M.abscessus_ATCC_1997 ATAGWAGLVSGTFAAVGIWSLFETGVYTLAGQGSNFIEAGVAFTVDIVVS
MAV_4571|M.avium_104 RALPEQWRMRGLHKHVTRALCLVT-----IGFGLYMVPQALGWA------
* : . .
Mflv_0093|M.gilvum_PYR-GCK WPTFIAFAAGLATYVAVALATKPAHMRGLDIQVARDLDDILDDADRFEKE
Mvan_0815|M.vanbaalenii_PYR-1 WPTFIAFAAAILTYVSVSLATRPAHMRGLDIRVAQDIDDALDDPDAFEKE
TH_3825|M.thermoresistible__bu G--------------------GPSGVR----------DTPSDTPREMHPR
MSMEG_4462|M.smegmatis_MC2_155 LAT----------------TRTPAPVLQ-------VWNDRLAGRDQTATA
MAB_4639|M.abscessus_ATCC_1997 VAVSWTTEPKPAAELAGLVYSETPHAFSSDEPASGWFRQPVKLAMTALIL
MAV_4571|M.avium_104 --------------------------------------------------
Mflv_0093|M.gilvum_PYR-GCK PEPVS----
Mvan_0815|M.vanbaalenii_PYR-1 PELAKAT--
TH_3825|M.thermoresistible__bu NALA-----
MSMEG_4462|M.smegmatis_MC2_155 GEIPTATS-
MAB_4639|M.abscessus_ATCC_1997 VVALNLIFH
MAV_4571|M.avium_104 ---------