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M. smegmatis MC2 155 MSMEG_4462 (-)

annotation: sodium:solute symporter
coordinates: 4541971 - 4543458
length: 495

VGKPLDIAIVAVYLIAMLAFGFWGKTRTKDSADFLVAGRRLGPTLYTGTMAAVVLGGASTVGGVGLGYKW
GLSGMWLVVAIAVGLLALSLLFAGRIQRLKVYTVAQMLSLRYGVDATSASGVVMVTYTLMLSVTSTIAYA
TVFNVLFGTGRTVSVLIGGAVVMLYSSIGGMWSITLTDMVQFILKTIGVFFLLLPFTWNRAGGLDGIRER
AGDAVFSLTAIGTETIITFFVVYSFGMLIGQDIWQRVFTARSPQVAKWGGTTAALYCVAYGVAGALIGAA
ASTFLPDVEAKDDVYAQIAESILPVGISGLVLAAAVAAMMSTASGALIATATVARTDVRPLLLRLVGRRT
ETVTDDPSLEVHADRRYVVVLGIVVIVIAALLNDVVGALTIAYDILVGGLLVPILGGFVWKRATGAGALV
AMGVGTVVTLGTMAIVGDVLANDPIYWGLATSLVAYVAVSLATTRTPAPVLQVWNDRLAGRDQTATAGEI
PTATS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4462--100% (495)sodium:solute symporter
M. smegmatis MC2 155MSMEG_5303putP2e-2525.66% (491) sodium/proline symporter
M. smegmatis MC2 155MSMEG_3689-5e-2322.46% (521) sodium:solute symporter

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_0093-8e-4128.36% (476) Na+/solute symporter
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4639-3e-2220.47% (513) putative Na+/solute symporter
M. marinum M-----
M. avium 104MAV_3167-1e-0526.25% (259) ABC transporter, ATP-binding protein CydC
M. thermoresistible (build 8)TH_3825-3e-3526.39% (432) PUTATIVE putative Na+/solute symporter
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0815-1e-3828.45% (478) Na+/solute symporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0093|M.gilvum_PYR-GCK          -----------MILLGVAISIAVVVAVGFFVSTRIKGDSSNFLVGGRMLP
Mvan_0815|M.vanbaalenii_PYR-1       -----------MILLGVAISIAVVVAVGFFVSRRIEGDSSNFLVGGRMLP
TH_3825|M.thermoresistible__bu      -----------MILTGVAVFLLVLTVSGVVSARRVRGDCANYLVAGRALP
MSMEG_4462|M.smegmatis_MC2_155      -------MGKPLDIAIVAVYLIAMLAFGFWGKTRTK-DSADFLVAGRRLG
MAB_4639|M.abscessus_ATCC_1997      MTGSLRLDAGPVDYVLIAIYFVFVLGIGLLARRGVS-SSIDFFLSGRSLP
MAV_3167|M.avium_104                -------MPRPDSFASASSGRPLLAAAGLLSPRLPR-LAAAITLGVLSLG
                                                     :     :   *.         .    :.   * 

Mflv_0093|M.gilvum_PYR-GCK          FWLVGGALMGAAVDTNATLGNTDLAYEFGFWAGACLPLGLALCLLITGIF
Mvan_0815|M.vanbaalenii_PYR-1       FWLVGGALMGAAVDTNATLGNTDLAFGFGFWAGATLPLGLALCLTITGIF
TH_3825|M.thermoresistible__bu      AVLVAAVLIAQPVDSNATIGNADLSAAFGFWAGAALPIGLALCLLLMGLF
MSMEG_4462|M.smegmatis_MC2_155      PTLYTGTMAAVVLGGASTVGGVGLGYKWG-LSGMWLVVAIAVGLLALSLL
MAB_4639|M.abscessus_ATCC_1997      AWVTGLAFVSANLGAVEIMGMSANGAQFGMVGMHYFWIGAVPAILFLGIV
MAV_3167|M.avium_104                SALALAGVSAWLITRAWQMPPVLDLSVAAVAVRMFAISRGVLHYCERLVT
                                      :    . .  :     :         .           .       : 

Mflv_0093|M.gilvum_PYR-GCK          FAKPMNRMGLTSFPDYYRLRFG-RSVEIGASILLAVAFCMLVAGNLVAGG
Mvan_0815|M.vanbaalenii_PYR-1       FAKPMNRMGLTSFPDYYRLRFG-RSVEVGASLLLVVAFCMLVAGNLVAGG
TH_3825|M.thermoresistible__bu      FARRLRAAQVVTLPEYFGNRFG-RGVEVASSALTVGSFAILLAGNLVAIG
MSMEG_4462|M.smegmatis_MC2_155      FAGRIQRLKVYTVAQMLSLRYG-VDATSASGVVMVTYTLMLSVTSTIAYA
MAB_4639|M.abscessus_ATCC_1997      MMPFFYGSQVRSVPEYMLHRFG-VGAHLVNATGFAVAQVLIAGVNLYLLG
MAV_3167|M.avium_104                HDTALRAAGAARVAVYQRLTRGGAAAAVRLHSGELVARVGADVDELANVL
                                        :       ..       *   .                  .     

Mflv_0093|M.gilvum_PYR-GCK          LLFNYFLGMPHWLGVVLIAAIAVAYTGTGGLIADAYTAIIQMGLILAGAI
Mvan_0815|M.vanbaalenii_PYR-1       LLFNYFLGMPYWLGVVLIAAIAVAYTGTGGLIADAYTAIIQMALILAGAI
TH_3825|M.thermoresistible__bu      FLLERFLGVSYTIGILVTVPLALLYTITGGMFASVYTGVAQVVVNIVGVF
MSMEG_4462|M.smegmatis_MC2_155      TVFNVLFGTGRTVSVLIGGAVVMLYSSIGGMWSITLTDMVQFILKTIGVF
MAB_4639|M.abscessus_ATCC_1997      TIVNVLLGWPLWVSVIAAAAIVLCYITLGGLSAAIYNEVLQFFVIVAALL
MAV_3167|M.avium_104                VRALVPMGVAAVLAAAATAVVAAISPAAGGALAICLLVAGFVAPRLAGRA
                                          :*    :.      :.      **  :        .     .  

Mflv_0093|M.gilvum_PYR-GCK          GLFFWMTTTHG--LDIADGTGPFALGQLSDPAQG---AVINWATLIALGI
Mvan_0815|M.vanbaalenii_PYR-1       GLFVWMSSTHG--IDIAEGTGPFAFGQLSDPAQG---AVINWATLIALGI
TH_3825|M.thermoresistible__bu      ALVVWVAATHG--FTAPDGMGAGALSQLTSSESG---AVINWATIIALGL
MSMEG_4462|M.smegmatis_MC2_155      FLLLPFTWNRA--GGLDGIRERAGDAVFSLTAIG---TETIITFFVVYSF
MAB_4639|M.abscessus_ATCC_1997      PLTIVGLHQVGGWQGLQDKVSAGQMSSWPGNELSGFSDNLLSVIGIVFGL
MAV_3167|M.avium_104                AATQEDIARQQH-SQRDRAAMLALEHAPELRIAGLLPEVIAESQRRQRAW
                                                                     .              . 

Mflv_0093|M.gilvum_PYR-GCK          GDIVAIDFMAR-------VFSAKSPEAARRACFTAAAGTAAICVPFGLVV
Mvan_0815|M.vanbaalenii_PYR-1       GDVVAIDFMAR-------VFSAKSPDAARKACFSAATGTVAICVPFGLVV
TH_3825|M.thermoresistible__bu      GNLVAIDLMQR-------VFSARDPGAAQRACFAAAGGILLLCLPLSFVA
MSMEG_4462|M.smegmatis_MC2_155      GMLIGQDIWQR-------VFTARSPQVAKWGGTTAALYCVAYGVAGALIG
MAB_4639|M.abscessus_ATCC_1997      GFVLSFGYWTTNFVEVQRALASESLSAARRTPIIGAFPKMFIPFIVVIPG
MAV_3167|M.avium_104                GAALDAAGKPAA------VAEAMPTAAIGASVLGAVVAAIGMAHAVAPTT
                                    *  :              .  :    .       ..              

Mflv_0093|M.gilvum_PYR-GCK          LAAHSFLP-AELDGP-------------VLFVLLDQYAPAGLTVLVLCGL
Mvan_0815|M.vanbaalenii_PYR-1       LAAHSFMP-AELDGP-------------VLFVLLDQYAPAGLTVLVLCGL
TH_3825|M.thermoresistible__bu      LAAVGIVGDSAGDGP-------------ILYALLGEYAPAWLAIIVISGL
MSMEG_4462|M.smegmatis_MC2_155      AAASTFLPDVEAKDD-------------VYAQIAESILPVGISGLVLAAA
MAB_4639|M.abscessus_ATCC_1997      MICAVLVPQMVAYKAGQPTSDPNLTYSNSLLYLMKEVLPNGVLGVAITGL
MAV_3167|M.avium_104                LAVLMLLPLSAFEAMT------------PLPAAAVQLTRSRIAARRLLEL
                                         ::                            .     :    :   

Mflv_0093|M.gilvum_PYR-GCK          MGASMSTANGAILAISNVCVRNLGGVRR--VHEPGRKDP-----LLRAAR
Mvan_0815|M.vanbaalenii_PYR-1       VGASMSTANGAILAISNVCVRNLGGVRR--VHEPGKRDP-----LLRATR
TH_3825|M.thermoresistible__bu      LAATLTTVSGILLSTASVLVRNVLRIDTGVLAPPAAMTPR----MLRATR
MSMEG_4462|M.smegmatis_MC2_155      VAAMMSTASGALIATATVARTDVRPLLLRLVGRRTETVTDDPSLEVHADR
MAB_4639|M.abscessus_ATCC_1997      LASFMAGMAANVSAFNTVFSYDLWQRYIRKDRPDGYYLR-----IGRIAT
MAV_3167|M.avium_104                TATEPPRPAGSVPRPTGPGRLTADIHSGHDGAARESRVT----LDLRPGA
                                     .:  .   . :                                  :   

Mflv_0093|M.gilvum_PYR-GCK          VAMAPMTLFSILFAIYVQQTGILLTLAFDLMLACLIVPFILGLVWRRGTT
Mvan_0815|M.vanbaalenii_PYR-1       IAMVPMTLFSIAFAIYVKQTGILLTLAFDLLLACLAVPFILGLYWRRGTV
TH_3825|M.thermoresistible__bu      WATLPMAALAAVVALRVPQTGILLTLAFDLLLASLVVPFILGLYWSRGGA
MSMEG_4462|M.smegmatis_MC2_155      RYVVVLGIVVIVIAALLNDVVGALTIAYDILVGGLLVPILGGFVWKRATG
MAB_4639|M.abscessus_ATCC_1997      VGATVIAIGTAFIAANYNNVMNYLQTLFAFFNAPLFATFILGMFWRRMTA
MAV_3167|M.avium_104                RLAVTGASGCGKTTLLMTLAGLLPPLQGQVVLDGVALSEFDECELARAIV
                                                 :     .         ..   :  . :      *   

Mflv_0093|M.gilvum_PYR-GCK          TAALAAIAVGFTVRIGLFVLTPT-----------MFGVENTILYIPNDLV
Mvan_0815|M.vanbaalenii_PYR-1       KAAMAAMVVGFVVRVGLFVLTPT-----------IYGVDNTILYIPNTLV
TH_3825|M.thermoresistible__bu      AAAAAAVVVGIGVRLTYFVLAPT-----------IYGVDNTLLYLPNDWV
MSMEG_4462|M.smegmatis_MC2_155      AGALVAMGVGTVVTLGTMAIVGD-----------VLANDPIYWGLATSLV
MAB_4639|M.abscessus_ATCC_1997      TAGWAGLVSGTFAAVGIWSLFETG-------VYTLAGQGSNFIEAGVAFT
MAV_3167|M.avium_104                FFAEDAHVFATTVRDNLLVARGDCPDDELTDALGAVGLDDWLAGLPDGLS
                                      .  .   .  .                       .             

Mflv_0093|M.gilvum_PYR-GCK          SASFDGWPTFIAFAAGLATYVAVALATKPAHMRGLDIQVARDLDDILDDA
Mvan_0815|M.vanbaalenii_PYR-1       GAAFDGWPTFIAFAAAILTYVSVSLATRPAHMRGLDIRVAQDIDDALDDP
TH_3825|M.thermoresistible__bu      SAXXRGG--------------------GPSGVR----------DTPSDTP
MSMEG_4462|M.smegmatis_MC2_155      AYVAVSLAT----------------TRTPAPVLQ-------VWNDRLAGR
MAB_4639|M.abscessus_ATCC_1997      VDIVVSVAVSWTTEPKPAAELAGLVYSETPHAFSSDEPASGWFRQPVKLA
MAV_3167|M.avium_104                TVLTGGAQAISAGQRRRLLLARAVISPARIVLLDEPTEHLDAGDAERLLR
                                         .                                            

Mflv_0093|M.gilvum_PYR-GCK          DRFEKEPEPVS------------------------------
Mvan_0815|M.vanbaalenii_PYR-1       DAFEKEPELAKAT----------------------------
TH_3825|M.thermoresistible__bu      REMHPRNALA-------------------------------
MSMEG_4462|M.smegmatis_MC2_155      DQTATAGEIPTATS---------------------------
MAB_4639|M.abscessus_ATCC_1997      MTALILVVALNLIFH--------------------------
MAV_3167|M.avium_104                DLLAPDSRLLSPPRTVVVATHHLPEGIGCRELRVDRGPAAG