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VPEAVQEADLLTAAAVALNRHAALLRELGSVFAAAGHELYLVGGSVRDALLGRLSPDLDFTTDARPERVQ EIVRPWADAVWDTGIEFGTVGVGKSDHRMEITTFRADSYDRVSRHPEVRFGDCLEGDLVRRDFTTNAMAV RVTATGPGEFLDPLGGLAALRAKVLDTPAAPSGSFGDDPLRMLRAARFVSQLGFAVAPRVRAAIEEMAPQ LARISAERVAAELDKLLVGEDPAAGIDLMVQSGMGAVVLPEIGGMRMAIDEHHQHKDVYQHSLTVLRQAI ALEDDGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMVRKRMRALKYSKQMIDDISQLVYL HLRFHGYGDGKWTDSAVRRYVTDAGALLPRLHKLVRADCTTRNKRRAARLQASYDRLEERIAELAAQEDL DRVRPDLDGNQIMAVLDIPAGPQVGEAWRYLKELRLERGPLSTEEATTELLSWWKSRGNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3937c | pcnA | - | 100% (480) | poly(A) polymerase PCNA (polynucleotide adenylyltransferase) (NTP polymerase) (RNA adenylating enzyme) (poly(A) polymerase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0845 | - | 0.0 | 77.80% (482) | metal dependent phosphohydrolase |
| M. tuberculosis H37Rv | Rv3907c | pcnA | 0.0 | 100.00% (480) | poly(A) polymerase |
| M. leprae Br4923 | MLBr_02697 | pcnA | 0.0 | 84.10% (478) | pcnA |
| M. abscessus ATCC 19977 | MAB_4934c | - | 0.0 | 76.73% (477) | Poly(A) polymerase PcnA |
| M. marinum M | MMAR_5471 | pcnA | 0.0 | 88.96% (480) | poly(a) polymerase PcnA |
| M. avium 104 | MAV_5294 | - | 0.0 | 87.06% (479) | tRNA adenylyltransferase |
| M. smegmatis MC2 155 | MSMEG_6926 | - | 0.0 | 82.71% (480) | tRNA adenylyltransferase |
| M. thermoresistible (build 8) | TH_0512 | pcnA | 0.0 | 80.71% (482) | PROBABLE POLY(A) POLYMERASE PCNA (POLYNUCLEOTIDE |
| M. ulcerans Agy99 | MUL_5060 | pcnA | 0.0 | 88.54% (480) | poly(a) polymerase PcnA |
| M. vanbaalenii PYR-1 | Mvan_6061 | - | 0.0 | 77.45% (479) | metal dependent phosphohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0845|M.gilvum_PYR-GCK MGSPGPVGSPDVSDPISDAERLATAQVALNRRGDVLRDLGRVFADNGHEL
Mvan_6061|M.vanbaalenii_PYR-1 -----------MPDPTSDSELLAAAQVALNVHGGVLRELGRLFGDHGHQL
MSMEG_6926|M.smegmatis_MC2_155 -----------MPEAAATAELLAGALVALNRRAGVLRELGAVFAAAGHEL
Mb3937c|M.bovis_AF2122/97 -----------MPEAVQEADLLTAAAVALNRHAALLRELGSVFAAAGHEL
Rv3907c|M.tuberculosis_H37Rv -----------MPEAVQEADLLTAAAVALNRHAALLRELGSVFAAAGHEL
MMAR_5471|M.marinum_M -----------MPETVQDADLLTAAAVALNRHAAVLGELGSAFADAGHDL
MUL_5060|M.ulcerans_Agy99 -----------MPETVQDADLLTAAAVALNRHAAVLRELGSAFADAGHDL
MLBr_02697|M.leprae_Br4923 ---------MNVPEAAQDTDLLTVAAVTLNRHTPVLRDLGSVFAASGHEL
MAV_5294|M.avium_104 -----------MPDAAQDAELLTAAAVALNKHAPMLRELGSAFDAAGHQL
TH_0512|M.thermoresistible__bu -----------VPNAVEDAELLAGAAVALNRHAELLRDIGTVFADAGHEL
MAB_4934c|M.abscessus_ATCC_199 -----------MPESIPTAELLATAAVTLNRHKKLLSELGALFDSAGFDL
:.:. :: *: * *:** : :* ::* * *.:*
Mflv_0845|M.gilvum_PYR-GCK YLVGGPVRDALLGRFDPDKNDLDFTTDARPEQMQRFLRGWGDALWDTGIE
Mvan_6061|M.vanbaalenii_PYR-1 YLVGGSVRDALLGRLG---TDLDFTTDARPDQMLPFLRGWGDALWDTGID
MSMEG_6926|M.smegmatis_MC2_155 YLVGGSVRDALLGRLTEN-SDLDFTTDARPEQMQKFLRGWSDALWDTGIE
Mb3937c|M.bovis_AF2122/97 YLVGGSVRDALLGRL---SPDLDFTTDARPERVQEIVRPWADAVWDTGIE
Rv3907c|M.tuberculosis_H37Rv YLVGGSVRDALLGRL---SPDLDFTTDARPERVQEIVRPWADAVWDTGIE
MMAR_5471|M.marinum_M YLVGGSVRDALLGRLK--SPDLDFTTDARPQQVQKIVRSWADAVWDTGIE
MUL_5060|M.ulcerans_Agy99 YLVGGSVRDALLGRLK--SPDLDFTTDARPQQILKIVRPWADAVWDTGIE
MLBr_02697|M.leprae_Br4923 YLVGGSVRDALLGRLD--SPDLDFATDAGPEQVQQIMRRWADNLWETGIE
MAV_5294|M.avium_104 YLVGGSVRDALLGRL---SPDLDFTTDARPDQVQQILRRWADNLWDTGIE
TH_0512|M.thermoresistible__bu YLVGGSVRDALLGRL---GTDLDFTTDARPEQMQKMLRPWAEAMWDTGIE
MAB_4934c|M.abscessus_ATCC_199 YLVGGSVRDAALGKPG---IDLDFTTDARPEQVQNLVTGWAEAIWDTGIA
*****.**** **: ****:*** *::: :: *.: :*:***
Mflv_0845|M.gilvum_PYR-GCK FGTLGVGKGEDRLEITTFRADTYDKVSRNPEVRFGDNLADDLVRRDFTVN
Mvan_6061|M.vanbaalenii_PYR-1 FGTLGVAKGGDRLEITTFRADSYDQVSRHPEVRYGDNLADDLVRRDFTVN
MSMEG_6926|M.smegmatis_MC2_155 FGTIGVGKGDDRLEITTFRADSYDQVSRNPTVEFGDNLGDDLVRRDFTIN
Mb3937c|M.bovis_AF2122/97 FGTVGVGKSDHRMEITTFRADSYDRVSRHPEVRFGDCLEGDLVRRDFTTN
Rv3907c|M.tuberculosis_H37Rv FGTVGVGKSDHRMEITTFRADSYDRVSRHPEVRFGDCLEGDLVRRDFTTN
MMAR_5471|M.marinum_M FGTIGIAKNDYRLEITTFRADSYDQVSRHPEVRFGERLEDDLVRRDFTVN
MUL_5060|M.ulcerans_Agy99 FGTIGIAKNDYRLEITTFRADSYDQVSRHPEVRFGERLEDDLVRRDFTVN
MLBr_02697|M.leprae_Br4923 FGTIGVGKGDYRLEITTFRADRYDQVSRNPEVRFSDRLDDDLVRRDFTVN
MAV_5294|M.avium_104 FGTVGVGKGDRRLEITTFRADTYDQVSRNPQVRFGNRLEDDLVRRDFTTN
TH_0512|M.thermoresistible__bu FGTVGVAKRGLRLEITTFRADSYDQVSRHPEVRFGDRLDDDLVRRDFTVN
MAB_4934c|M.abscessus_ATCC_199 FGTIGVARRGQRVEITTFRSDSYDQQSRNPEVVFGDSLEGDLVRRDFTVN
***:*:.: *:******:* **: **:* * :.: * .******** *
Mflv_0845|M.gilvum_PYR-GCK AMAVRVTADGPT---EFLDPLDGLSALRDGVLDTPAAPEVSFGDDPLRML
Mvan_6061|M.vanbaalenii_PYR-1 AMAVRITPGGPT---EFLDPLDGLAALRDQVLDTPSEPEVSFSDDPLRML
MSMEG_6926|M.smegmatis_MC2_155 AMAVRITADGPG---EFHDPLGGLAAARDKVLDTPSAPEVSFGDDPLRML
Mb3937c|M.bovis_AF2122/97 AMAVRVTATGPG---EFLDPLGGLAALRAKVLDTPAAPSGSFGDDPLRML
Rv3907c|M.tuberculosis_H37Rv AMAVRVTATGPG---EFLDPLGGLAALRAKVLDTPAAPSGSFGDDPLRML
MMAR_5471|M.marinum_M AMAVRITASGPG---EFLDPLGGLSVLRDKVLDTPAAPSVSFGDDPLRML
MUL_5060|M.ulcerans_Agy99 AMAVRITASGPG---EFLDPLGGLSVLRDKVLDTPAAPSVSFGDDPLRML
MLBr_02697|M.leprae_Br4923 AMAVRIASYGPG---EFFDPLGGLAALRVRVLETPAAPSVSFGDDPLRML
MAV_5294|M.avium_104 AMAVRITPDGPG---EFLDPLGGLAALRQRVLDTPATPEESFGDDPLRML
TH_0512|M.thermoresistible__bu AMAVRITPDSPGGFGEFHDPLGGLAHLRARTLDTPAEPEVSFGDDPLRML
MAB_4934c|M.abscessus_ATCC_199 AMAVKIGPDGPG---EFCDPLNGLEALRAGVLDTPSAPEISFGDDPLRML
****:: . .* ** ***.** * .*:**: *. **.*******
Mflv_0845|M.gilvum_PYR-GCK RAARFVSQLGFTVAPRVRRALEEMSSQLSRITAERVAAELDKLLLGADPV
Mvan_6061|M.vanbaalenii_PYR-1 RAARFVSQLGFAVAPRVRRALQEMAPQLSRITAERVAAELDKLLLGADPV
MSMEG_6926|M.smegmatis_MC2_155 RAARFVSQLGFSVAPRVLEALIEMAPQLERITAERVAAELDKLLLGADPV
Mb3937c|M.bovis_AF2122/97 RAARFVSQLGFAVAPRVRAAIEEMAPQLARISAERVAAELDKLLVGEDPA
Rv3907c|M.tuberculosis_H37Rv RAARFVSQLGFAVAPRVRAAIEEMAPQLARISAERVAAELDKLLVGEDPA
MMAR_5471|M.marinum_M RAARFVSQLGFAVAPRVRDAIEEMAPQLARISAERVAAELDKLLLGENPV
MUL_5060|M.ulcerans_Agy99 RAARFVSQLGFAVAPRVRDAIEEMAPQLARISAERVAAELDKLLLGEDPV
MLBr_02697|M.leprae_Br4923 RAARFVSQLGFTVAPQVHAAIEEMASQLARISAERVSTELDKLLLGNDPA
MAV_5294|M.avium_104 RAARFVSQLGFTVAPRVREAIERMAPQLARISAERVAAELDKLVLGDDPV
TH_0512|M.thermoresistible__bu RAARFVSQLRFTVAPRVRAAIERMAPQLARISPERVQAELDKLILGDDPV
MAB_4934c|M.abscessus_ATCC_199 RAARFVSQLGFTVAPRVLEALHAMADQLGRITAERVQTELDKLIVGAHPV
********* *:***:* *: *: ** **:.*** :*****::* .*.
Mflv_0845|M.gilvum_PYR-GCK AGLDLMVDTGLGEVVLPEVGAMRMAIDEHHQHKDVYQHSLTVLRQAMDLE
Mvan_6061|M.vanbaalenii_PYR-1 AGLNLMVETGLGDVVLPEIGAMRMAIDEHHQHKDVYQHSLTVLRQAMDLE
MSMEG_6926|M.smegmatis_MC2_155 AGIDLMVQTGMGAVVLPEVGEMRMAIDEHHQHKDVYWHSLTVLRQAIDLE
Mb3937c|M.bovis_AF2122/97 AGIDLMVQSGMGAVVLPEIGGMRMAIDEHHQHKDVYQHSLTVLRQAIALE
Rv3907c|M.tuberculosis_H37Rv AGIDLMVQSGMGAVVLPEIGGMRMAIDEHHQHKDVYQHSLTVLRQAIALE
MMAR_5471|M.marinum_M AGIDLMVHTGMGEVVLPEIGGMQMAIDEHHQHKDVYQHSLTVLRQAIELE
MUL_5060|M.ulcerans_Agy99 AGIDLMVHTGMGEVVLPEIGGMQMAIDEHHQHKDVYQHSLTVLRQAIELE
MLBr_02697|M.leprae_Br4923 AGIDLLVQTGMGEVVLPEIGDMRMAIDEHHQHKDVYQHSLTVLRQAIALE
MAV_5294|M.avium_104 AGIDLLVHSGMGEVVLPEIGGMQMAIDEHHQHKDVYQHSLTVLRQAIALE
TH_0512|M.thermoresistible__bu AGIDLMVETGMGEVVLPEVGAMRMEIDEHHQHKDVYQHSLQVLRQAIALE
MAB_4934c|M.abscessus_ATCC_199 AGIDLLVDSGLGAVVLPEVGQMQLTIDEHHQHKDVYRHSLTVLEQAVDLE
**::*:*.:*:* *****:* *:: *********** *** **.**: **
Mflv_0845|M.gilvum_PYR-GCK GADGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMTRKRMR
Mvan_6061|M.vanbaalenii_PYR-1 GPEGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMTRKRLR
MSMEG_6926|M.smegmatis_MC2_155 D-DGPDLVLRWAALLHDIGKPATRKHEPDGGVSFHHHEVVGAKMVRKRMR
Mb3937c|M.bovis_AF2122/97 D-DGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMVRKRMR
Rv3907c|M.tuberculosis_H37Rv D-DGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMVRKRMR
MMAR_5471|M.marinum_M D-DGPDLVLRWAALLHDIGKPTTRRHEANGGVSFHHHEVVGAKMVRKRMR
MUL_5060|M.ulcerans_Agy99 D-EGPDLALRWAALLHDIGKPATRRHEANGGVSFHHHEVVGAKMVRNRMR
MLBr_02697|M.leprae_Br4923 D-NGPDLVLRWAALLHDIGKPATRRHELNGGVSFHHHEVVGAKMVRKRMR
MAV_5294|M.avium_104 D-DGPDLVLRWAALLHDIGKPATRRHEPNGGVSFHHHEVVGAKMVRKRLR
TH_0512|M.thermoresistible__bu D-GEPDLVLRWAALLHDIGKPATRRLESDGRVSFHHHEVVGAKMTRKRMR
MAB_4934c|M.abscessus_ATCC_199 D-EGPDLVLRWAALLHDIGKPATRRHEEGGGVSFHHHEVVGAKMVRKRMR
. ***.*************:**: * .* *************.*:*:*
Mflv_0845|M.gilvum_PYR-GCK ELKYSKQMISDVSQLVYLHLRFHGYGDGRWTDSAVRRYVTDAGPLLTRLH
Mvan_6061|M.vanbaalenii_PYR-1 ELKYSKQMISDVSQLVYLHLRFHGYGDGRWTDSAVRRYVTDAGPLLGQLH
MSMEG_6926|M.smegmatis_MC2_155 ALKYSKQMVEDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLSRLH
Mb3937c|M.bovis_AF2122/97 ALKYSKQMIDDISQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGALLPRLH
Rv3907c|M.tuberculosis_H37Rv ALKYSKQMIDDISQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGALLPRLH
MMAR_5471|M.marinum_M ALKYSKQMVDDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLARLH
MUL_5060|M.ulcerans_Agy99 ALKYSKQMVDDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLARLH
MLBr_02697|M.leprae_Br4923 ALKYAKQLVDDVSQLVYLHLRFHGYGEGKWTDSAVRRYVTDAGPLLSRLH
MAV_5294|M.avium_104 ALKYSKQMVDDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLPRLH
TH_0512|M.thermoresistible__bu ALKYSKQMVEDVSQLVYLHLRFHGYGDGKWTDSAVRRYVADAGHLLPKLH
MAB_4934c|M.abscessus_ATCC_199 ALKYSKQMVDDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLPRLH
***:**::.*:**************:*:**********:*** ** :**
Mflv_0845|M.gilvum_PYR-GCK KLVRADCTTRNKRRAARLQANYDDLERRIQDLAAREDLARVRPDIDGNEI
Mvan_6061|M.vanbaalenii_PYR-1 KLVRADCTTRNKRRAARLQASYDDLERRIEELAAKEDLARVRPDIDGNEI
MSMEG_6926|M.smegmatis_MC2_155 KLVRADCTTRNKRRAARLRANYDDLEARIAELAAKEDLQRVRPDLDGNEI
Mb3937c|M.bovis_AF2122/97 KLVRADCTTRNKRRAARLQASYDRLEERIAELAAQEDLDRVRPDLDGNQI
Rv3907c|M.tuberculosis_H37Rv KLVRADCTTRNKRRAARLQASYDRLEERIAELAAQEDLDRVRPDLDGNQI
MMAR_5471|M.marinum_M KLVRADCTTRNKRRAARLQASYDRLEERITELAAQEDLDRVRPDLDGNQI
MUL_5060|M.ulcerans_Agy99 KLVRADCTTRNKRRAARLQSSYDRLEERITELAAQEDLDRVRPDLDGNQI
MLBr_02697|M.leprae_Br4923 KLVRADCTTRNQRRAARLQDSYDRLEARIAELAAEEDLARVRPDLDGNQI
MAV_5294|M.avium_104 KLVRADCTTRNKRRAARLQASYDRLEARIAELAAQEDLARVRPDLDGNQI
TH_0512|M.thermoresistible__bu KLVRADCTTRNRRRAARLQANYDNLERRIAELQAKEDLARVRPDLDGNEI
MAB_4934c|M.abscessus_ATCC_199 KLVRADCTTRNKRRAARLQANYDGLEERIAELAAKEDLARVRPDLDGNQI
***********:******: .** ** ** :* *.*** *****:***:*
Mflv_0845|M.gilvum_PYR-GCK MKILGIPPGPQVGQAWNHLKELRLDRGPLDHDEAVEELVRWWNERGGPRV
Mvan_6061|M.vanbaalenii_PYR-1 MRILDIPPGPQVGQAWNHLKELRLDRGPLEYDEAVAELLKWWNEKGRPNV
MSMEG_6926|M.smegmatis_MC2_155 MQILGIPPGPQVGEAWKYLKELRLERGPLSHDEAVDELLKWWNARG----
Mb3937c|M.bovis_AF2122/97 MAVLDIPAGPQVGEAWRYLKELRLERGPLSTEEATTELLSWWKSRGNR--
Rv3907c|M.tuberculosis_H37Rv MAVLDIPAGPQVGEAWRYLKELRLERGPLSTEEATTELLSWWKSRGNR--
MMAR_5471|M.marinum_M MTLLDIPAGPQVGEAWRYLKELRLERGPLTIEEAKAELLSWWQSRGNP--
MUL_5060|M.ulcerans_Agy99 MTLLDIPAGPQVGEAWRYLKELRLERGPLTIEEAKAELLSWWRSRGNP--
MLBr_02697|M.leprae_Br4923 MALLDIPAGPQVGEAWRFLKELRLDRGPLTNEEATAELLAWWKTRQSQGL
MAV_5294|M.avium_104 MEILGIPAGPQVGEAWRFLKELRLERGPLDPDEATAELLSWWRSRGNG--
TH_0512|M.thermoresistible__bu MEILGIGPGPQVGEAWRYLKELRLDRGPLSREEAVDELLKWWEARQNGQK
MAB_4934c|M.abscessus_ATCC_199 MELLGVPAGPIVGQAWQFLKELRLERGPLDHDEAVEALRQWWAGRS----
* :*.: .** **:**..******:**** :** * ** :
Mflv_0845|M.gilvum_PYR-GCK -
Mvan_6061|M.vanbaalenii_PYR-1 -
MSMEG_6926|M.smegmatis_MC2_155 -
Mb3937c|M.bovis_AF2122/97 -
Rv3907c|M.tuberculosis_H37Rv -
MMAR_5471|M.marinum_M -
MUL_5060|M.ulcerans_Agy99 -
MLBr_02697|M.leprae_Br4923 L
MAV_5294|M.avium_104 -
TH_0512|M.thermoresistible__bu -
MAB_4934c|M.abscessus_ATCC_199 -