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PDAAQDAELLTAAAVALNKHAPMLRELGSAFDAAGHQLYLVGGSVRDALLGRLSPDLDFTTDARPDQVQQ ILRRWADNLWDTGIEFGTVGVGKGDRRLEITTFRADTYDQVSRNPQVRFGNRLEDDLVRRDFTTNAMAVR ITPDGPGEFLDPLGGLAALRQRVLDTPATPEESFGDDPLRMLRAARFVSQLGFTVAPRVREAIERMAPQL ARISAERVAAELDKLVLGDDPVAGIDLLVHSGMGEVVLPEIGGMQMAIDEHHQHKDVYQHSLTVLRQAIA LEDDGPDLVLRWAALLHDIGKPATRRHEPNGGVSFHHHEVVGAKMVRKRLRALKYSKQMVDDVSQLVYLH LRFHGYGDGKWTDSAVRRYVTDAGPLLPRLHKLVRADCTTRNKRRAARLQASYDRLEARIAELAAQEDLA RVRPDLDGNQIMEILGIPAGPQVGEAWRFLKELRLERGPLDPDEATAELLSWWRSRGNG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_5294 | - | - | 100% (480) | tRNA adenylyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3937c | pcnA | 0.0 | 87.06% (479) | poly(A) polymerase PCNA (polynucleotide adenylyltransferase) |
M. gilvum PYR-GCK | Mflv_0845 | - | 0.0 | 79.05% (482) | metal dependent phosphohydrolase |
M. tuberculosis H37Rv | Rv3907c | pcnA | 0.0 | 87.06% (479) | poly(A) polymerase |
M. leprae Br4923 | MLBr_02697 | pcnA | 0.0 | 85.36% (478) | pcnA |
M. abscessus ATCC 19977 | MAB_4934c | - | 0.0 | 78.20% (477) | Poly(A) polymerase PcnA |
M. marinum M | MMAR_5471 | pcnA | 0.0 | 87.08% (480) | poly(a) polymerase PcnA |
M. smegmatis MC2 155 | MSMEG_6926 | - | 0.0 | 82.92% (480) | tRNA adenylyltransferase |
M. thermoresistible (build 8) | TH_0512 | pcnA | 0.0 | 81.37% (483) | PROBABLE POLY(A) POLYMERASE PCNA (POLYNUCLEOTIDE |
M. ulcerans Agy99 | MUL_5060 | pcnA | 0.0 | 86.67% (480) | poly(a) polymerase PcnA |
M. vanbaalenii PYR-1 | Mvan_6061 | - | 0.0 | 79.75% (479) | metal dependent phosphohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0845|M.gilvum_PYR-GCK MGSPGPVGSPDVSDPISDAERLATAQVALNRRGDVLRDLGRVFADNGHEL Mvan_6061|M.vanbaalenii_PYR-1 -----------MPDPTSDSELLAAAQVALNVHGGVLRELGRLFGDHGHQL MSMEG_6926|M.smegmatis_MC2_155 -----------MPEAAATAELLAGALVALNRRAGVLRELGAVFAAAGHEL Mb3937c|M.bovis_AF2122/97 -----------MPEAVQEADLLTAAAVALNRHAALLRELGSVFAAAGHEL Rv3907c|M.tuberculosis_H37Rv -----------MPEAVQEADLLTAAAVALNRHAALLRELGSVFAAAGHEL MMAR_5471|M.marinum_M -----------MPETVQDADLLTAAAVALNRHAAVLGELGSAFADAGHDL MUL_5060|M.ulcerans_Agy99 -----------MPETVQDADLLTAAAVALNRHAAVLRELGSAFADAGHDL MAV_5294|M.avium_104 -----------MPDAAQDAELLTAAAVALNKHAPMLRELGSAFDAAGHQL MLBr_02697|M.leprae_Br4923 ---------MNVPEAAQDTDLLTVAAVTLNRHTPVLRDLGSVFAASGHEL TH_0512|M.thermoresistible__bu -----------VPNAVEDAELLAGAAVALNRHAELLRDIGTVFADAGHEL MAB_4934c|M.abscessus_ATCC_199 -----------MPESIPTAELLATAAVTLNRHKKLLSELGALFDSAGFDL :.:. :: *: * *:** : :* ::* * *.:* Mflv_0845|M.gilvum_PYR-GCK YLVGGPVRDALLGRFDPDKNDLDFTTDARPEQMQRFLRGWGDALWDTGIE Mvan_6061|M.vanbaalenii_PYR-1 YLVGGSVRDALLGRLG---TDLDFTTDARPDQMLPFLRGWGDALWDTGID MSMEG_6926|M.smegmatis_MC2_155 YLVGGSVRDALLGRLTEN-SDLDFTTDARPEQMQKFLRGWSDALWDTGIE Mb3937c|M.bovis_AF2122/97 YLVGGSVRDALLGRL---SPDLDFTTDARPERVQEIVRPWADAVWDTGIE Rv3907c|M.tuberculosis_H37Rv YLVGGSVRDALLGRL---SPDLDFTTDARPERVQEIVRPWADAVWDTGIE MMAR_5471|M.marinum_M YLVGGSVRDALLGRLK--SPDLDFTTDARPQQVQKIVRSWADAVWDTGIE MUL_5060|M.ulcerans_Agy99 YLVGGSVRDALLGRLK--SPDLDFTTDARPQQILKIVRPWADAVWDTGIE MAV_5294|M.avium_104 YLVGGSVRDALLGRL---SPDLDFTTDARPDQVQQILRRWADNLWDTGIE MLBr_02697|M.leprae_Br4923 YLVGGSVRDALLGRLD--SPDLDFATDAGPEQVQQIMRRWADNLWETGIE TH_0512|M.thermoresistible__bu YLVGGSVRDALLGRL---GTDLDFTTDARPEQMQKMLRPWAEAMWDTGIE MAB_4934c|M.abscessus_ATCC_199 YLVGGSVRDAALGKPG---IDLDFTTDARPEQVQNLVTGWAEAIWDTGIA *****.**** **: ****:*** *::: :: *.: :*:*** Mflv_0845|M.gilvum_PYR-GCK FGTLGVGKGEDRLEITTFRADTYDKVSRNPEVRFGDNLADDLVRRDFTVN Mvan_6061|M.vanbaalenii_PYR-1 FGTLGVAKGGDRLEITTFRADSYDQVSRHPEVRYGDNLADDLVRRDFTVN MSMEG_6926|M.smegmatis_MC2_155 FGTIGVGKGDDRLEITTFRADSYDQVSRNPTVEFGDNLGDDLVRRDFTIN Mb3937c|M.bovis_AF2122/97 FGTVGVGKSDHRMEITTFRADSYDRVSRHPEVRFGDCLEGDLVRRDFTTN Rv3907c|M.tuberculosis_H37Rv FGTVGVGKSDHRMEITTFRADSYDRVSRHPEVRFGDCLEGDLVRRDFTTN MMAR_5471|M.marinum_M FGTIGIAKNDYRLEITTFRADSYDQVSRHPEVRFGERLEDDLVRRDFTVN MUL_5060|M.ulcerans_Agy99 FGTIGIAKNDYRLEITTFRADSYDQVSRHPEVRFGERLEDDLVRRDFTVN MAV_5294|M.avium_104 FGTVGVGKGDRRLEITTFRADTYDQVSRNPQVRFGNRLEDDLVRRDFTTN MLBr_02697|M.leprae_Br4923 FGTIGVGKGDYRLEITTFRADRYDQVSRNPEVRFSDRLDDDLVRRDFTVN TH_0512|M.thermoresistible__bu FGTVGVAKRGLRLEITTFRADSYDQVSRHPEVRFGDRLDDDLVRRDFTVN MAB_4934c|M.abscessus_ATCC_199 FGTIGVARRGQRVEITTFRSDSYDQQSRNPEVVFGDSLEGDLVRRDFTVN ***:*:.: *:******:* **: **:* * :.: * .******** * Mflv_0845|M.gilvum_PYR-GCK AMAVRVTADGPT---EFLDPLDGLSALRDGVLDTPAAPEVSFGDDPLRML Mvan_6061|M.vanbaalenii_PYR-1 AMAVRITPGGPT---EFLDPLDGLAALRDQVLDTPSEPEVSFSDDPLRML MSMEG_6926|M.smegmatis_MC2_155 AMAVRITADGPG---EFHDPLGGLAAARDKVLDTPSAPEVSFGDDPLRML Mb3937c|M.bovis_AF2122/97 AMAVRVTATGPG---EFLDPLGGLAALRAKVLDTPAAPSGSFGDDPLRML Rv3907c|M.tuberculosis_H37Rv AMAVRVTATGPG---EFLDPLGGLAALRAKVLDTPAAPSGSFGDDPLRML MMAR_5471|M.marinum_M AMAVRITASGPG---EFLDPLGGLSVLRDKVLDTPAAPSVSFGDDPLRML MUL_5060|M.ulcerans_Agy99 AMAVRITASGPG---EFLDPLGGLSVLRDKVLDTPAAPSVSFGDDPLRML MAV_5294|M.avium_104 AMAVRITPDGPG---EFLDPLGGLAALRQRVLDTPATPEESFGDDPLRML MLBr_02697|M.leprae_Br4923 AMAVRIASYGPG---EFFDPLGGLAALRVRVLETPAAPSVSFGDDPLRML TH_0512|M.thermoresistible__bu AMAVRITPDSPGGFGEFHDPLGGLAHLRARTLDTPAEPEVSFGDDPLRML MAB_4934c|M.abscessus_ATCC_199 AMAVKIGPDGPG---EFCDPLNGLEALRAGVLDTPSAPEISFGDDPLRML ****:: . .* ** ***.** * .*:**: *. **.******* Mflv_0845|M.gilvum_PYR-GCK RAARFVSQLGFTVAPRVRRALEEMSSQLSRITAERVAAELDKLLLGADPV Mvan_6061|M.vanbaalenii_PYR-1 RAARFVSQLGFAVAPRVRRALQEMAPQLSRITAERVAAELDKLLLGADPV MSMEG_6926|M.smegmatis_MC2_155 RAARFVSQLGFSVAPRVLEALIEMAPQLERITAERVAAELDKLLLGADPV Mb3937c|M.bovis_AF2122/97 RAARFVSQLGFAVAPRVRAAIEEMAPQLARISAERVAAELDKLLVGEDPA Rv3907c|M.tuberculosis_H37Rv RAARFVSQLGFAVAPRVRAAIEEMAPQLARISAERVAAELDKLLVGEDPA MMAR_5471|M.marinum_M RAARFVSQLGFAVAPRVRDAIEEMAPQLARISAERVAAELDKLLLGENPV MUL_5060|M.ulcerans_Agy99 RAARFVSQLGFAVAPRVRDAIEEMAPQLARISAERVAAELDKLLLGEDPV MAV_5294|M.avium_104 RAARFVSQLGFTVAPRVREAIERMAPQLARISAERVAAELDKLVLGDDPV MLBr_02697|M.leprae_Br4923 RAARFVSQLGFTVAPQVHAAIEEMASQLARISAERVSTELDKLLLGNDPA TH_0512|M.thermoresistible__bu RAARFVSQLRFTVAPRVRAAIERMAPQLARISPERVQAELDKLILGDDPV MAB_4934c|M.abscessus_ATCC_199 RAARFVSQLGFTVAPRVLEALHAMADQLGRITAERVQTELDKLIVGAHPV ********* *:***:* *: *: ** **:.*** :*****::* .*. Mflv_0845|M.gilvum_PYR-GCK AGLDLMVDTGLGEVVLPEVGAMRMAIDEHHQHKDVYQHSLTVLRQAMDLE Mvan_6061|M.vanbaalenii_PYR-1 AGLNLMVETGLGDVVLPEIGAMRMAIDEHHQHKDVYQHSLTVLRQAMDLE MSMEG_6926|M.smegmatis_MC2_155 AGIDLMVQTGMGAVVLPEVGEMRMAIDEHHQHKDVYWHSLTVLRQAIDLE Mb3937c|M.bovis_AF2122/97 AGIDLMVQSGMGAVVLPEIGGMRMAIDEHHQHKDVYQHSLTVLRQAIALE Rv3907c|M.tuberculosis_H37Rv AGIDLMVQSGMGAVVLPEIGGMRMAIDEHHQHKDVYQHSLTVLRQAIALE MMAR_5471|M.marinum_M AGIDLMVHTGMGEVVLPEIGGMQMAIDEHHQHKDVYQHSLTVLRQAIELE MUL_5060|M.ulcerans_Agy99 AGIDLMVHTGMGEVVLPEIGGMQMAIDEHHQHKDVYQHSLTVLRQAIELE MAV_5294|M.avium_104 AGIDLLVHSGMGEVVLPEIGGMQMAIDEHHQHKDVYQHSLTVLRQAIALE MLBr_02697|M.leprae_Br4923 AGIDLLVQTGMGEVVLPEIGDMRMAIDEHHQHKDVYQHSLTVLRQAIALE TH_0512|M.thermoresistible__bu AGIDLMVETGMGEVVLPEVGAMRMEIDEHHQHKDVYQHSLQVLRQAIALE MAB_4934c|M.abscessus_ATCC_199 AGIDLLVDSGLGAVVLPEVGQMQLTIDEHHQHKDVYRHSLTVLEQAVDLE **::*:*.:*:* *****:* *:: *********** *** **.**: ** Mflv_0845|M.gilvum_PYR-GCK GADGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMTRKRMR Mvan_6061|M.vanbaalenii_PYR-1 GPEGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMTRKRLR MSMEG_6926|M.smegmatis_MC2_155 D-DGPDLVLRWAALLHDIGKPATRKHEPDGGVSFHHHEVVGAKMVRKRMR Mb3937c|M.bovis_AF2122/97 D-DGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMVRKRMR Rv3907c|M.tuberculosis_H37Rv D-DGPDLVLRWAALLHDIGKPATRRHEPDGGVSFHHHEVVGAKMVRKRMR MMAR_5471|M.marinum_M D-DGPDLVLRWAALLHDIGKPTTRRHEANGGVSFHHHEVVGAKMVRKRMR MUL_5060|M.ulcerans_Agy99 D-EGPDLALRWAALLHDIGKPATRRHEANGGVSFHHHEVVGAKMVRNRMR MAV_5294|M.avium_104 D-DGPDLVLRWAALLHDIGKPATRRHEPNGGVSFHHHEVVGAKMVRKRLR MLBr_02697|M.leprae_Br4923 D-NGPDLVLRWAALLHDIGKPATRRHELNGGVSFHHHEVVGAKMVRKRMR TH_0512|M.thermoresistible__bu D-GEPDLVLRWAALLHDIGKPATRRLESDGRVSFHHHEVVGAKMTRKRMR MAB_4934c|M.abscessus_ATCC_199 D-EGPDLVLRWAALLHDIGKPATRRHEEGGGVSFHHHEVVGAKMVRKRMR . ***.*************:**: * .* *************.*:*:* Mflv_0845|M.gilvum_PYR-GCK ELKYSKQMISDVSQLVYLHLRFHGYGDGRWTDSAVRRYVTDAGPLLTRLH Mvan_6061|M.vanbaalenii_PYR-1 ELKYSKQMISDVSQLVYLHLRFHGYGDGRWTDSAVRRYVTDAGPLLGQLH MSMEG_6926|M.smegmatis_MC2_155 ALKYSKQMVEDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLSRLH Mb3937c|M.bovis_AF2122/97 ALKYSKQMIDDISQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGALLPRLH Rv3907c|M.tuberculosis_H37Rv ALKYSKQMIDDISQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGALLPRLH MMAR_5471|M.marinum_M ALKYSKQMVDDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLARLH MUL_5060|M.ulcerans_Agy99 ALKYSKQMVDDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLARLH MAV_5294|M.avium_104 ALKYSKQMVDDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLPRLH MLBr_02697|M.leprae_Br4923 ALKYAKQLVDDVSQLVYLHLRFHGYGEGKWTDSAVRRYVTDAGPLLSRLH TH_0512|M.thermoresistible__bu ALKYSKQMVEDVSQLVYLHLRFHGYGDGKWTDSAVRRYVADAGHLLPKLH MAB_4934c|M.abscessus_ATCC_199 ALKYSKQMVDDVSQLVYLHLRFHGYGDGKWTDSAVRRYVTDAGPLLPRLH ***:**::.*:**************:*:**********:*** ** :** Mflv_0845|M.gilvum_PYR-GCK KLVRADCTTRNKRRAARLQANYDDLERRIQDLAAREDLARVRPDIDGNEI Mvan_6061|M.vanbaalenii_PYR-1 KLVRADCTTRNKRRAARLQASYDDLERRIEELAAKEDLARVRPDIDGNEI MSMEG_6926|M.smegmatis_MC2_155 KLVRADCTTRNKRRAARLRANYDDLEARIAELAAKEDLQRVRPDLDGNEI Mb3937c|M.bovis_AF2122/97 KLVRADCTTRNKRRAARLQASYDRLEERIAELAAQEDLDRVRPDLDGNQI Rv3907c|M.tuberculosis_H37Rv KLVRADCTTRNKRRAARLQASYDRLEERIAELAAQEDLDRVRPDLDGNQI MMAR_5471|M.marinum_M KLVRADCTTRNKRRAARLQASYDRLEERITELAAQEDLDRVRPDLDGNQI MUL_5060|M.ulcerans_Agy99 KLVRADCTTRNKRRAARLQSSYDRLEERITELAAQEDLDRVRPDLDGNQI MAV_5294|M.avium_104 KLVRADCTTRNKRRAARLQASYDRLEARIAELAAQEDLARVRPDLDGNQI MLBr_02697|M.leprae_Br4923 KLVRADCTTRNQRRAARLQDSYDRLEARIAELAAEEDLARVRPDLDGNQI TH_0512|M.thermoresistible__bu KLVRADCTTRNRRRAARLQANYDNLERRIAELQAKEDLARVRPDLDGNEI MAB_4934c|M.abscessus_ATCC_199 KLVRADCTTRNKRRAARLQANYDGLEERIAELAAKEDLARVRPDLDGNQI ***********:******: .** ** ** :* *.*** *****:***:* Mflv_0845|M.gilvum_PYR-GCK MKILGIPPGPQVGQAWNHLKELRLDRGPLDHDEAVEELVRWWNERGGPRV Mvan_6061|M.vanbaalenii_PYR-1 MRILDIPPGPQVGQAWNHLKELRLDRGPLEYDEAVAELLKWWNEKGRPNV MSMEG_6926|M.smegmatis_MC2_155 MQILGIPPGPQVGEAWKYLKELRLERGPLSHDEAVDELLKWWNARG---- Mb3937c|M.bovis_AF2122/97 MAVLDIPAGPQVGEAWRYLKELRLERGPLSTEEATTELLSWWKSRGNR-- Rv3907c|M.tuberculosis_H37Rv MAVLDIPAGPQVGEAWRYLKELRLERGPLSTEEATTELLSWWKSRGNR-- MMAR_5471|M.marinum_M MTLLDIPAGPQVGEAWRYLKELRLERGPLTIEEAKAELLSWWQSRGNP-- MUL_5060|M.ulcerans_Agy99 MTLLDIPAGPQVGEAWRYLKELRLERGPLTIEEAKAELLSWWRSRGNP-- MAV_5294|M.avium_104 MEILGIPAGPQVGEAWRFLKELRLERGPLDPDEATAELLSWWRSRGNG-- MLBr_02697|M.leprae_Br4923 MALLDIPAGPQVGEAWRFLKELRLDRGPLTNEEATAELLAWWKTRQSQGL TH_0512|M.thermoresistible__bu MEILGIGPGPQVGEAWRYLKELRLDRGPLSREEAVDELLKWWEARQNGQK MAB_4934c|M.abscessus_ATCC_199 MELLGVPAGPIVGQAWQFLKELRLERGPLDHDEAVEALRQWWAGRS---- * :*.: .** **:**..******:**** :** * ** : Mflv_0845|M.gilvum_PYR-GCK - Mvan_6061|M.vanbaalenii_PYR-1 - MSMEG_6926|M.smegmatis_MC2_155 - Mb3937c|M.bovis_AF2122/97 - Rv3907c|M.tuberculosis_H37Rv - MMAR_5471|M.marinum_M - MUL_5060|M.ulcerans_Agy99 - MAV_5294|M.avium_104 - MLBr_02697|M.leprae_Br4923 L TH_0512|M.thermoresistible__bu - MAB_4934c|M.abscessus_ATCC_199 -