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M. bovis AF2122 / 97 Mb3580 (echA20)

annotation: enoyl-CoA hydratase
coordinates: 3932368 - 3933111
length: 247

MPITSTTPEPGIVAVTVDYPPVNAIPSKAWFDLADAVTAAGANSDTRAVILRAEGRGFNAGVDIKEMQRT
EGFTALIDANRGCFAAFRAVYECAVPVIAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGALGAA
THLSRLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIAAKDTRVIRAAKEALNF
IDVQRVNASYRMEQGFTFELNLAGVADEHRDAFVKKS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3580echA20-100% (247)enoyl-CoA hydratase
M. bovis AF2122 / 97Mb1099cechA86e-2234.65% (202) enoyl-CoA hydratase
M. bovis AF2122 / 97Mb3408echA183e-1930.92% (207) enoyl-CoA hydratase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1490-1e-11986.83% (243) enoyl-CoA hydratase
M. tuberculosis H37RvRv3550echA201e-138100.00% (247) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-2e-2133.17% (199) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_0606c-1e-11078.37% (245) enoyl-CoA hydratase
M. marinum MMMAR_5039echA201e-12893.47% (245) enoyl-CoA hydratase EchA20
M. avium 104MAV_0610-1e-12490.53% (243) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_6001-1e-12187.65% (243) enoyl-CoA hydratase
M. thermoresistible (build 8)TH_1755echA201e-12489.30% (243) PROBABLE ENOYL-CoA HYDRATASE ECHA20 (ENOYL HYDRASE)
M. ulcerans Agy99MUL_4113echA201e-12893.06% (245) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_5266-1e-11986.42% (243) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3580|M.bovis_AF2122/97            MPITSTTPE--PGIVAVTVDYP-PVNAIPSKAWFDLADAVTAAGANSDTR
Rv3550|M.tuberculosis_H37Rv         MPITSTTPE--PGIVAVTVDYP-PVNAIPSKAWFDLADAVTAAGANSDTR
MMAR_5039|M.marinum_M               MTITSTTAE--PGIVAITVDYP-PVNAIPSRGWFELADALTAAGADLETR
MUL_4113|M.ulcerans_Agy99           MTITSTTAE--PGIVAITVDYP-PVNAIPSRGWFELADALTAAGADLETR
Mflv_1490|M.gilvum_PYR-GCK          MPITTKTVE--PGIVAVTVDYP-PVNAIPSRGWFELADIITAAGRDQSTH
Mvan_5266|M.vanbaalenii_PYR-1       MPITTKTVE--PGIVSVTVDYP-PVNAIPSRGWFELADTITAAGRDHSTH
TH_1755|M.thermoresistible__bu      MPITTTSPE--PGIVSVTVDYP-PVNAIPSRGWFELADAITAAGRDQQTH
MSMEG_6001|M.smegmatis_MC2_155      MTITSTTVE--PGIVSVTVNYP-PVNAVPSRGWFELADAITAAGRDPQTH
MAV_0610|M.avium_104                MPITSKTIE--PGIVAVTVDFP-PVNAIPSRGWFDLADTVTAAGQDPETH
MAB_0606c|M.abscessus_ATCC_199      MGITTATVE--PGIVTVTVDYP-KVNAIPSRGWFELADAILAAGNDPSTH
MLBr_02402|M.leprae_Br4923          MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELDIDPDVG
                                    *   :   :    :  :*:: *  :**: *:   ::::     . : .. 

Mb3580|M.bovis_AF2122/97            AVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPV
Rv3550|M.tuberculosis_H37Rv         AVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPV
MMAR_5039|M.marinum_M               AVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPV
MUL_4113|M.ulcerans_Agy99           AVILRADGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPV
Mflv_1490|M.gilvum_PYR-GCK          VVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGCYEAFRAVYECAVPV
Mvan_5266|M.vanbaalenii_PYR-1       VVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGCYEAFRAVYECAVPV
TH_1755|M.thermoresistible__bu      VVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGCYEAFRAVYECAVPV
MSMEG_6001|M.smegmatis_MC2_155      VVILRAEGRGFNAGVDIKEMQNTEGFTALIDANRGCFAAFKAVYECEVPV
MAV_0610|M.avium_104                VVILRAEGRGFNAGVDIKEMQRTEGFTALIDANRGCFAAFRAVYECAVPV
MAB_0606c|M.abscessus_ATCC_199      VVILRAEGRGFNAGADIKEMQATDGFTALIDTNRGCFEAFSAVYRCKVPV
MLBr_02402|M.leprae_Br4923          AILITGSPKVFAAGADIKEMASLT-FTDAFDAD--FFSAWGKLAAVRTPM
                                    .::: .. : * **.*****     **  :*::   : *:  :    .*:

Mb3580|M.bovis_AF2122/97            IAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGAL---GAATHLS
Rv3550|M.tuberculosis_H37Rv         IAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGAL---GAATHLS
MMAR_5039|M.marinum_M               IAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGAL---GAATHLS
MUL_4113|M.ulcerans_Agy99           IAAVNGFCVGGGIGLVGNSDVIVASEDATFGLPEVERGAL---GAATHLS
Mflv_1490|M.gilvum_PYR-GCK          VAAVNGFCVGGGIGLVGNADVIVASDDAKFGLPEVERGAL---GAATHLS
Mvan_5266|M.vanbaalenii_PYR-1       VAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLS
TH_1755|M.thermoresistible__bu      VAAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLS
MSMEG_6001|M.smegmatis_MC2_155      VTAVNGFCVGGGIGLVGNSDVIVASDDAKFGLPEVERGAL---GAATHLS
MAV_0610|M.avium_104                VAAVNGFCVGGGIGLVGNSDVIVASDDATFGLPEVERGAL---GAATHLS
MAB_0606c|M.abscessus_ATCC_199      IAAVNGFCLGGGIGLVGNADVIVAADDAVFSVPEVDRGAL---GTATHLQ
MLBr_02402|M.leprae_Br4923          IAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQRLT
                                    ::** *:.:***  *.  .*:::*:: * *. **:. *.*   * : :* 

Mb3580|M.bovis_AF2122/97            RLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIA
Rv3550|M.tuberculosis_H37Rv         RLVPQHLMRRLFFTAATVDAATLQHFGSVHEVVSRDQLDEAALRVARDIA
MMAR_5039|M.marinum_M               RLVPQHLMRRLFFTAATVDAATLHHFGSVHEVVPRAELDESALRVARDIA
MUL_4113|M.ulcerans_Agy99           RLVPQHLMRRLFFTAATVDAATLHHFGSVHEVVPRAELDESALRVARDIA
Mflv_1490|M.gilvum_PYR-GCK          RLVPQHLMRRLFFTAATVGADTLHHFGSVHEVVPRADLDEAALRVARDIA
Mvan_5266|M.vanbaalenii_PYR-1       RLVPQHMMRRLFFTAATVTADTLHHFGSVHEVVPRADLDEAALRVARDIA
TH_1755|M.thermoresistible__bu      RLVPQHMMRRLFFTAATVDAHTLHHFGSVHEVVPRAELDEAALRVARDIA
MSMEG_6001|M.smegmatis_MC2_155      RLVPQHMMRRLFFTAATVDAATLHHFGSVHEVVPREDLDEAALRVARDIA
MAV_0610|M.avium_104                RLVPQHLMRRLFFTAATVDAATLHHFGSVHEVVPRGELDDAALRVAREIA
MAB_0606c|M.abscessus_ATCC_199      RLVPQHVMRRMFYTAAKIDAKTLHHYGSIHEVVPRAELDEAALRVARDIA
MLBr_02402|M.leprae_Br4923          RAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVATTIS
                                    * : :     :: *. .: *   .: * : .**   :*   *  **  *:

Mb3580|M.bovis_AF2122/97            AKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFV
Rv3550|M.tuberculosis_H37Rv         AKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLAGVADEHRDAFV
MMAR_5039|M.marinum_M               AKDTRVIRAAKEALNLIDVQRVNSSYRMEQGFTFELNLAGVADEHRDAFV
MUL_4113|M.ulcerans_Agy99           AKDTRVIRAAKEALNLIDVQRVNSSYRMEQGFTFELNLAGVADEHRDAFV
Mflv_1490|M.gilvum_PYR-GCK          SKDTRVIRAAKEALNFIDIQPVNARYRMEQGFTFELNLAGVSDEHRDAFA
Mvan_5266|M.vanbaalenii_PYR-1       SKDTRVIRAAKEALNFIDIQPVNARYRMEQGFTFELNLAGVSDEHRDAFA
TH_1755|M.thermoresistible__bu      AKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVADEHRDAFA
MSMEG_6001|M.smegmatis_MC2_155      TKDTRVIRAAKEALNFIDVQRVNASYRMEQGFTFELNLSGVSDEHRDAFA
MAV_0610|M.avium_104                AKDTRVIRAAKEALNFIDVQRVNSSYRMEQGFTFELNLAGVSDEHRDAFA
MAB_0606c|M.abscessus_ATCC_199      AKDTRVIRAAKEAINFIDPQDVESSYRMEQGFTFELNLAGVADEHRDAFV
MLBr_02402|M.leprae_Br4923          QMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQSEGMAAFI
                                      .  . * ****:*    . :      *: : ..  ::.  .*   ** 

Mb3580|M.bovis_AF2122/97            KKS-------
Rv3550|M.tuberculosis_H37Rv         KKS-------
MMAR_5039|M.marinum_M               KKS-------
MUL_4113|M.ulcerans_Agy99           KKS-------
Mflv_1490|M.gilvum_PYR-GCK          GTDKGSK---
Mvan_5266|M.vanbaalenii_PYR-1       GTEKGKA---
TH_1755|M.thermoresistible__bu      GTNKGKKQ--
MSMEG_6001|M.smegmatis_MC2_155      GTEKRAK---
MAV_0610|M.avium_104                GTQKGKK---
MAB_0606c|M.abscessus_ATCC_199      ETGKPKGN--
MLBr_02402|M.leprae_Br4923          EKRAPQFTHR
                                     .