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VLASCPARSGAAVADAIKSAVGVQPSGVEHKTLRRMDLVRYLAGGHTTYPPEGFVAGSDVIGTTNPAAAQ AIVAAIGTWPPAAGRASALIDSLGGAVGDMDPEGSAFPWCRQSAVVQWYVNTPSDGQVATANKWLSDAHH AVQHFSVGGYVNYLEANAAASQYFGANLSRLTTVRRKYDPDRIMYSGLDFSTRQVAERLLPALGFRVRFG VLVIRCALCTDTVKRLGTLPNLTWSRLKVNVAVTQEQAGVMDLPALPVRRTPRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3386c | - | - | 100% (264) | hypothetical protein Mb3386c |
| M. bovis AF2122 / 97 | Mb0064 | - | 2e-55 | 54.74% (190) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3351c | - | 1e-152 | 100.00% (264) | hypothetical protein Rv3351c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2456 | - | 9e-09 | 25.26% (190) | hypothetical protein MAB_2456 |
| M. marinum M | MMAR_1179 | - | 2e-78 | 71.58% (190) | oxidoreductase |
| M. avium 104 | MAV_0089 | - | 2e-56 | 56.32% (190) | FAD binding domain-containing protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1431 | - | 5e-76 | 70.53% (190) | oxidoreductase |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3386c|M.bovis_AF2122/97 --------------------------------------------------
Rv3351c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1179|M.marinum_M --------MISRQTLLRGAAAATAAGLGSALFGSARAVAEP-VSGWSALA
MUL_1431|M.ulcerans_Agy99 --------MISRQTFLRGAAAATAAGLGSALFGSARAVAEP-VSGWSALA
MAV_0089|M.avium_104 -----MAREISRQTFLRGAVGALAAG---AMLGAPRVGADPRPSGWEGLS
MAB_2456|M.abscessus_ATCC_1997 MDPQSRPALMTRRTVLSAGAMLALGSTSLIGCSPVLPNEIPAGVRWEDLR
Mb3386c|M.bovis_AF2122/97 --------------------------------------------------
Rv3351c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1179|M.marinum_M SSIGGRVLLPSNGASFTSGKQVFNSLYNNSNPAAVVTVTSQADVEKAVAF
MUL_1431|M.ulcerans_Agy99 SSIGGRVLLPSNGASFTSGKQVFNSLYNNSNPAAVVTVTSQADVEKAVAF
MAV_0089|M.avium_104 TALGGKVLLP-DSPQFAGAKQVFNTNYNGSTPAAVVTPTSAADVQKAMAF
MAB_2456|M.abscessus_ATCC_1997 RSLSG-ALVVRGDAAMDESGRAFNPLFDVNHPGAVAFCASDQDVARCVEF
Mb3386c|M.bovis_AF2122/97 --------------------------------------------------
Rv3351c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1179|M.marinum_M AAANKLKIAPRGGGHSYIGASTAVGAMVIDLRGLPGGVNFDAGSGTVTVP
MUL_1431|M.ulcerans_Agy99 AAANKLKIAPRGGGHSYIGASTAVGAMVIDLRGLPGGVNFDAGSGTVTVP
MAV_0089|M.avium_104 AAAHNLKVAPRSGGHSYTGASTANGTMVLDLRQLPGDANYDAATGQVTVT
MAB_2456|M.abscessus_ATCC_1997 ATSARLPIAARGGGHSYAAYCIPNDGLVVDLARMAAVS---VTGTRAVVG
Mb3386c|M.bovis_AF2122/97 --------------------------------------------------
Rv3351c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1179|M.marinum_M AGVSLTDVHQVLAGAGRAIPTGSCPTVGVGGLALGGGMGADSRHAGLTCD
MUL_1431|M.ulcerans_Agy99 AGVSLTDVHQVLAGAGRAIPTGSCPTVGVGGLALGGGMGADSRHAGLTCN
MAV_0089|M.avium_104 PATSLYTMHRTLAAVGRGVPTGTCPSVGAAGHALGGGMGAQSRHAGLLCD
MAB_2456|M.abscessus_ATCC_1997 AGARLIDVYAGIAGAGRMLAGGSCPTVGIAGLTLGGGVGVLTRRFGLTCD
Mb3386c|M.bovis_AF2122/97 --------------------------------------------------
Rv3351c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1179|M.marinum_M ALRSATVVLPSGETVTASAEDHPDLFWALRGGGGGNFGVTTAMTFETFPV
MUL_1431|M.ulcerans_Agy99 ALRSATVVLPSGETVTASAEDHPDLFWALRGGGGGNFGVTTAMTFETFPV
MAV_0089|M.avium_104 QLTSASVVLPSGQAVTASTASNPDLFWALRGGGGGNFGVTTSLTFATFPT
MAB_2456|M.abscessus_ATCC_1997 QLISARVVTADGKIRVVSADTESDLFWAIRGVGGGNFCIATELAFETAAS
Mb3386c|M.bovis_AF2122/97 -------------------------------------------------M
Rv3351c|M.tuberculosis_H37Rv -------------------------------------------------M
MMAR_1179|M.marinum_M ADSDVVRVDFTPSSAAQVLAGWQTWLAAADRDTWGLVDMSVSAAQANCHV
MUL_1431|M.ulcerans_Agy99 ADSDVVRVDFTPSSAAQVLAGWQTWLAAADRDTWGLVDMSVSAAQANCHV
MAV_0089|M.avium_104 KDVDAVNLNFPPQSFAQVLVGWQNWLRTADPNSWALADATVDAMGVHCRI
MAB_2456|M.abscessus_ATCC_1997 TDLTVFTLDYAAGEMAPIVHRWLTFMAGAPDELWTTLHAIGGAIPQCRIV
:
Mb3386c|M.bovis_AF2122/97 LASCPARSGAAVADAIKSAVGVQPSGVEHKTLRRMDLVRYLAGGHTTYPP
Rv3351c|M.tuberculosis_H37Rv LASCPARSGAAVADAIKSAVGVQPSGVEHKTLRRMDLVRYLAGGHTTYPP
MMAR_1179|M.marinum_M LATCPAGAGRGVADAIKSAVGAQPTGIETKTFNHMELVKYLAGGSSASSP
MUL_1431|M.ulcerans_Agy99 LATCPAGAGRGVADAIKSAVGAQPTGIETKTFNHMELVKYLAGGSSASSP
MAV_0089|M.avium_104 LATCPAGSGNSAAAAITQAVGIQPSGVETHTFNYMDLVNYLAVGNLNPQP
MAB_2456|M.abscessus_ATCC_1997 GCVAQGVNSQDVIESLRGGIGVRAADSFIAEMTFLDAMKFMGGCTTLTVA
. . . . . :: .:* :.:. : :: :.::. .
Mb3386c|M.bovis_AF2122/97 EGFVAGSD-----------VIGTTNPAAAQAIVAAIGTWPPAAGRASALI
Rv3351c|M.tuberculosis_H37Rv EGFVAGSD-----------VIGTTNPAAAQAIVAAIGTWPPAAGRASALI
MMAR_1179|M.marinum_M RGFVAGSD-----------VIGTVNSAAAQAIVAAVGKWPPASGRASALV
MUL_1431|M.ulcerans_Agy99 RGFVAGSD-----------VIGTVNSAAAQAIVAAVGKSPPASGWASALV
MAV_0089|M.avium_104 LGYVGGSD-----------VFPTVNAAVAQGIAAAVNAFPRNAGRMLAIM
MAB_2456|M.abscessus_ATCC_1997 QCHPSWTGPGSGQLKREAFVASSRMVPHPDVDTARIETLLAGKPGLTFIF
. . :. * : . .: .* : :.
Mb3386c|M.bovis_AF2122/97 DSLGGAVGDMDPEGSAFPWCRQSAVVQWYVNTPSDGQVATANKWLSDAHH
Rv3351c|M.tuberculosis_H37Rv DSLGGAVGDMDPEGSAFPWCRQSAVVQWYVNTPSDGQVATANKWLSDAHH
MMAR_1179|M.marinum_M DTLTGAVGDIDPTATAFPWRRQSAVVQWYVETPSSGQTAAATKWINSAHQ
MUL_1431|M.ulcerans_Agy99 DTLTGAVGDIDPTATAFPWRRQSAVVQWYVETPSSGQTAAATKWINSAHQ
MAV_0089|M.avium_104 HALDGALATVAPAATAFPWRRQSALVQWYVET--SGDPAAATNWLASAHQ
MAB_2456|M.abscessus_ATCC_1997 DSLGGAVRRISPDATAFPHRQAAACIQIYHGVG--ADPAVAHERVSQARD
.:* **: : * .:*** : :* :* * . .: *.* : : .*:.
Mb3386c|M.bovis_AF2122/97 AVQHFS-VGGYVNYLEANAA--ASQYFGANLSRLTTVRRKYDPDRIMYSG
Rv3351c|M.tuberculosis_H37Rv AVQHFS-VGGYVNYLEANAA--ASQYFGANLSRLTTVRRKYDPDRIMYSG
MMAR_1179|M.marinum_M AVQQFS-VGGYVNYLEANTA--PSRYFGSNLSRLTQIRQRYDPSRLMYSG
MUL_1431|M.ulcerans_Agy99 AVQQFS-VGGYVNYLEANTA--LSRYFGSNLSRLTQIRQRYDPSRLMYSG
MAV_0089|M.avium_104 AVQQYS-VGGYVNYLEANQS--PARYFGPNLSRLSAVRQKYDPGRVMFSG
MAB_2456|M.abscessus_ATCC_1997 GLGDICGPAAYVNYIDPGMPDWATAYYGDNLPRLRGIAAAYDPKGIFRFA
.: . . ..****::.. . : *:* **.** : *** :: .
Mb3386c|M.bovis_AF2122/97 LDFSTRQVAERLLPALGFRVRFGVLVIRCALCTDTVKRLGTLPNLTWSRL
Rv3351c|M.tuberculosis_H37Rv LDFSTRQVAERLLPALGFRVRFGVLVIRCALCTDTVKRLGTLPNLTWSRL
MMAR_1179|M.marinum_M LNF-----------------------------------------------
MUL_1431|M.ulcerans_Agy99 LNF-----------------------------------------------
MAV_0089|M.avium_104 LNY-----------------------------------------------
MAB_2456|M.abscessus_ATCC_1997 QAVRP---------------------------------------------
Mb3386c|M.bovis_AF2122/97 KVNVAVTQEQAGVMDLPALPVRRTPRR
Rv3351c|M.tuberculosis_H37Rv KVNVAVTQEQAGVMDLPALPVRRTPRR
MMAR_1179|M.marinum_M ---------------------------
MUL_1431|M.ulcerans_Agy99 ---------------------------
MAV_0089|M.avium_104 ---------------------------
MAB_2456|M.abscessus_ATCC_1997 ---------------------------