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VALGAVATAVIINSGDSTSTKAIVGAPAPRTVISTSPRPTAPTSTSPHPSPSTLRPQLPPETVTTVAPPG TGPTTVPTRTPTAAPPQTAVPPPAPLNPRTVVYRVTGTKQLFDLVNVVYTDARGFPVTDFNVSLPWTKMV VLNPGVQTESVVATSLYSRLNCSIVNTGAQTVVASTNNAIIATCTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3235 | - | - | 100% (186) | hypothetical protein Mb3235 |
| M. bovis AF2122 / 97 | Mb2221c | mmpS3 | 2e-21 | 34.66% (176) | membrane protein |
| M. bovis AF2122 / 97 | Mb2535 | - | 5e-11 | 32.84% (134) | proline rich membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4674 | - | 1e-38 | 43.24% (185) | hypothetical protein Mflv_4674 |
| M. tuberculosis H37Rv | Rv3209 | - | 1e-104 | 100.00% (186) | hypothetical protein Rv3209 |
| M. leprae Br4923 | MLBr_00813 | - | 2e-49 | 58.38% (185) | hypothetical protein MLBr_00813 |
| M. abscessus ATCC 19977 | MAB_3529 | - | 4e-28 | 35.26% (190) | hypothetical protein MAB_3529 |
| M. marinum M | MMAR_1348 | - | 3e-69 | 67.01% (197) | putative threonine and proline rich protein |
| M. avium 104 | MAV_4157 | - | 1e-56 | 61.14% (193) | hypothetical protein MAV_4157 |
| M. smegmatis MC2 155 | MSMEG_1932 | - | 5e-42 | 48.65% (185) | MmpS3 protein |
| M. thermoresistible (build 8) | TH_1006 | - | 4e-22 | 58.54% (82) | CONSERVED HYPOTHETICAL THREONIN AND PROLINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_2531 | - | 1e-52 | 69.23% (143) | putative threonine and proline rich protein |
| M. vanbaalenii PYR-1 | Mvan_1793 | - | 2e-39 | 44.02% (184) | hypothetical protein Mvan_1793 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4674|M.gilvum_PYR-GCK MNRPYTAQSPYSLTPTERIRSGRASGRRGGGYGGSDVDELDRYGDSDTDA
Mvan_1793|M.vanbaalenii_PYR-1 MNKPYTAQSPYSLTPTERIRSPRG---RYGSYD----DDPDRYGDLDTDA
MSMEG_1932|M.smegmatis_MC2_155 MTRPYSPYDTATTNRHGDHAPEPGSYHGSQGYGYGSGYGRGAYAG-DYQD
TH_1006|M.thermoresistible__bu --------------------------------------------------
Mb3235|M.bovis_AF2122/97 ---------------------MALGAVATAVIIN-----------SGDST
Rv3209|M.tuberculosis_H37Rv ---------------------MALGAVATAVIIN-----------SGDST
MMAR_1348|M.marinum_M MLLRRRRISSRLVDAFEAPHIGLSARTSRSRPADWFITIGSNLARHAIAA
MUL_2531|M.ulcerans_Agy99 ---------------------MATARPPRARLA---------FRRRGQSS
MAV_4157|M.avium_104 MGTTLPHLDDRIRGYPDDDADDACDTDPYLNADYNWTGWPADSRWRPATA
MLBr_00813|M.leprae_Br4923 ---------MRLTETTSIRRTTTTSYSGHPIVDG-----------RQVAA
MAB_3529|M.abscessus_ATCC_1997 --MVGYRGDSRYSSDYEPYDDPYNSETAPQSTEYSGLDEDFEYRPPGSNE
Mflv_4674|M.gilvum_PYR-GCK LPPYRDYRPGDHDAHDAYDSDDYTDVENYDEYLDEARIDRRWMWIAG---
Mvan_1793|M.vanbaalenii_PYR-1 LPPF----PG----------DDY-DAEDYDGYIDEERLDRRWMWIAG---
MSMEG_1932|M.smegmatis_MC2_155 YDDYVRADGGNGGFD-----DGY---DDPDIEFYEEPLDRRWIWVAG---
TH_1006|M.thermoresistible__bu --------------------------------------------------
Mb3235|M.bovis_AF2122/97 ST------------------------------------------------
Rv3209|M.tuberculosis_H37Rv ST------------------------------------------------
MMAR_1348|M.marinum_M LKRHRRVDTIGPISNSAHTQYDTVRDVEDYPDDESYGGYSDYGYQDSQDD
MUL_2531|M.ulcerans_Agy99 LR-HR-----APLRHQRH--------------------------------
MAV_4157|M.avium_104 IVGAVVALGAIATAVIIN--------------------------------
MLBr_00813|M.leprae_Br4923 LLG-----------------------------------------------
MAB_3529|M.abscessus_ATCC_1997 NWKWVASIAG----------------------------------------
Mflv_4674|M.gilvum_PYR-GCK ------------------------------------VAGAILFVAVITVS
Mvan_1793|M.vanbaalenii_PYR-1 ------------------------------------VAGAILFVAVITAS
MSMEG_1932|M.smegmatis_MC2_155 ------------------------------------VAGAILLVAVICTV
TH_1006|M.thermoresistible__bu --------------------------------------------------
Mb3235|M.bovis_AF2122/97 -------------------------------------------------K
Rv3209|M.tuberculosis_H37Rv -------------------------------------------------K
MMAR_1348|M.marinum_M QDEYPDSYADLAWPADRRWRPVAAVLGVVVALGAITTALVINSGDSATTK
MUL_2531|M.ulcerans_Agy99 -------------------------------------------------R
MAV_4157|M.avium_104 ------------------------------------------SGDSASTK
MLBr_00813|M.leprae_Br4923 ------------------------------------------------SV
MAB_3529|M.abscessus_ATCC_1997 ---------------------------------------AVFAIAVIATA
Mflv_4674|M.gilvum_PYR-GCK MILGGGDSGSVSATVAAPLPTSSAPEPS---AAPSPRAAAPASPSLPAET
Mvan_1793|M.vanbaalenii_PYR-1 MILGGGDSGSVSATVASPLPSSSAPEPS---AAPAPRVAAPAVPSLPAET
MSMEG_1932|M.smegmatis_MC2_155 VILGGGDSGSVSATVADPTQTSQPATTAPQDASSTPRPLPPVAPSLSPET
TH_1006|M.thermoresistible__bu --------------------------------------------------
Mb3235|M.bovis_AF2122/97 AIVGAPAPRTVISTSPRPTAPTST---------SPHPSPSTLRPQLPPET
Rv3209|M.tuberculosis_H37Rv AIVGAPAPRTVISTSPRPTAPTST---------SPHPSPSTLRPQLPPET
MMAR_1348|M.marinum_M GKVGVPTPRTVISTTARTTAPSAPPRTAPYPSTSTRPGPGTSASQLPPET
MUL_2531|M.ulcerans_Agy99 GRLPIPAP-------APGQAPALP-----------RPNS-------PPET
MAV_4157|M.avium_104 ATVGASAPHSVTSAPATTKASVPP---------SASPSPSR---PLPAET
MLBr_00813|M.leprae_Br4923 AALCAIATAVIINSGDNATTKAIVG----------APTPR------PVLT
MAB_3529|M.abscessus_ATCC_1997 VVLSGGNDKPPAAAVTTPVPALTPVTTT----TAPPPPPSATSPAKPSTT
Mflv_4674|M.gilvum_PYR-GCK VTTVTPTAETPAPAPVAPSP--LLPAPQAAP-----PPAAAAPGTVTYRI
Mvan_1793|M.vanbaalenii_PYR-1 VTTVTPTAEIPTPAPTTPAP--LLPAPQAAP-----PPASAAPGTVTYRI
MSMEG_1932|M.smegmatis_MC2_155 VTTVTPSPTAPA-ATAEPAP--VAPPAEAAP-----PPA-VNPRAVTYTV
TH_1006|M.thermoresistible__bu -------------------------------------------------V
Mb3235|M.bovis_AF2122/97 VTTVAPPGTGPTTVPTRTP--TAAPPQTAVP-----PPAPLNPRTVVYRV
Rv3209|M.tuberculosis_H37Rv VTTVAPPGTGPTTVPTRTP--TAAPPQTAVP-----PPAPLNPRTVVYRV
MMAR_1348|M.marinum_M FTTVTPPGAAPTWPPTAVAPLPGMQPLPAEP-----PSAALNPRTVIYRV
MUL_2531|M.ulcerans_Agy99 FTTVTPPGAAPTWPPTAVAPLQGMQPLPAEP-----PSAALNPRTVIYRV
MAV_4157|M.avium_104 FTTVTSPSAAPSVAPSLTPGVAPAQTPTAAPPLAAAPTVTVDPRTVVYSV
MLBr_00813|M.leprae_Br4923 TPSIPLPATPSSTPPLLLLPDTATATIPHKA-----APPALHPRTVVYNV
MAB_3529|M.abscessus_ATCC_1997 TVTSTPAQETPTAEPSTEAP--PPEPPPSNPMLPPEGQRPITPAAFAYYV
:
Mflv_4674|M.gilvum_PYR-GCK TGNRALLDLVTIIYTDEQGALKTDVNAALPWTKTVVLNPGVTLSSVTATS
Mvan_1793|M.vanbaalenii_PYR-1 TGNRALLDLVTVIYTDAQGALQTDVNAALPWSKTIVLNPGVTLSSVTATS
MSMEG_1932|M.smegmatis_MC2_155 TGNRQLIDLVTIVYTDERGALQTDINVALPWTKTVVLDPGVELKSVTATS
TH_1006|M.thermoresistible__bu TGERPLLDVVTVVYTDAQGALQTDVNVALPWSKTIELNPGVELSSVTATS
Mb3235|M.bovis_AF2122/97 TGTKQLFDLVNVVYTDARGFPVTDFNVSLPWTKMVVLNPGVQTESVVATS
Rv3209|M.tuberculosis_H37Rv TGTKQLFDLVNVVYTDARGFPVTDFNVSLPWTKMVVLNPGVQTESVVATS
MMAR_1348|M.marinum_M TGTKQLLDMVNIVYTDARGFPVTEFNVALPWTKMVVLNPGVQTESVVATS
MUL_2531|M.ulcerans_Agy99 TGTKQLLDMVNIVYTDARGFPVTEFNVALPWTKMVVLNPGVQTESVVATS
MAV_4157|M.avium_104 SGSKQLLDLVNVVYTDAHGVPQTEFNVSLPWSKVVVLEPGVQTESVVATS
MLBr_00813|M.leprae_Br4923 TGMKELLDLVTVVYTDARGYPKTEFNVVLPWTKAVVLNLGVKTQSVVATS
MAB_3529|M.abscessus_ATCC_1997 TGNQTPGDLLTITYTDGNGMTRTVLGASLPWTMIVTPSPGITGGSITATS
:* : *::.: *** .* * ... ***: : . *: *:.***
Mflv_4674|M.gilvum_PYR-GCK VSGQLNCAILDANGSLIAVQNNNSIITNCTR
Mvan_1793|M.vanbaalenii_PYR-1 MSGQLNCAILDANGSLIAAQNNNSIITNCTR
MSMEG_1932|M.smegmatis_MC2_155 VAGQLNCSITDAAGNVLVNQANNTMIATCTQ
TH_1006|M.thermoresistible__bu VSSRLNCSITDADGNTLVSHRANTIIATCTR
Mb3235|M.bovis_AF2122/97 LYSRLNCSIVNTGAQTVVASTNNAIIATCTR
Rv3209|M.tuberculosis_H37Rv LYSRLNCSIVNTGAQTVVASTNNAIIATCTR
MMAR_1348|M.marinum_M IYGRLNCAIVNAQGQLVVASTNTSIIATCTR
MUL_2531|M.ulcerans_Agy99 IYGRLNCAIVNAQGQLVVASTNTSIIATCTR
MAV_4157|M.avium_104 FYGRLSCSIFNAAGQRVVASANASNMATCAR
MLBr_00813|M.leprae_Br4923 FHSQLHCSIVNAEGQPVVASTNNAVIATCTR
MAB_3529|M.abscessus_ATCC_1997 FASQVNCSITNSENQMLAVQNSNSIIARCAK
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