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LLRRRRISSRLVDAFEAPHIGLSARTSRSRPADWFITIGSNLARHAIAALKRHRRVDTIGPISNSAHTQY DTVRDVEDYPDDESYGGYSDYGYQDSQDDQDEYPDSYADLAWPADRRWRPVAAVLGVVVALGAITTALVI NSGDSATTKGKVGVPTPRTVISTTARTTAPSAPPRTAPYPSTSTRPGPGTSASQLPPETFTTVTPPGAAP TWPPTAVAPLPGMQPLPAEPPSAALNPRTVIYRVTGTKQLLDMVNIVYTDARGFPVTEFNVALPWTKMVV LNPGVQTESVVATSIYGRLNCAIVNAQGQLVVASTNTSIIATCTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1348 | - | - | 100% (326) | putative threonine and proline rich protein |
| M. marinum M | MMAR_3242 | mmpS3 | 2e-23 | 28.47% (288) | membrane protein MmpS3 |
| M. marinum M | MMAR_3854 | - | 5e-10 | 28.65% (192) | proline rich membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3235 | - | 4e-69 | 67.01% (197) | hypothetical protein Mb3235 |
| M. gilvum PYR-GCK | Mflv_4674 | - | 2e-46 | 42.13% (254) | hypothetical protein Mflv_4674 |
| M. tuberculosis H37Rv | Rv3209 | - | 4e-69 | 67.01% (197) | hypothetical protein Rv3209 |
| M. leprae Br4923 | MLBr_00813 | - | 9e-50 | 52.66% (207) | hypothetical protein MLBr_00813 |
| M. abscessus ATCC 19977 | MAB_3529 | - | 3e-28 | 29.28% (263) | hypothetical protein MAB_3529 |
| M. avium 104 | MAV_4157 | - | 2e-66 | 54.62% (249) | hypothetical protein MAV_4157 |
| M. smegmatis MC2 155 | MSMEG_1932 | - | 4e-47 | 44.53% (256) | MmpS3 protein |
| M. thermoresistible (build 8) | TH_1006 | - | 2e-21 | 56.10% (82) | CONSERVED HYPOTHETICAL THREONIN AND PROLINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_2531 | - | 8e-73 | 89.19% (148) | putative threonine and proline rich protein |
| M. vanbaalenii PYR-1 | Mvan_1793 | - | 8e-45 | 43.14% (255) | hypothetical protein Mvan_1793 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4674|M.gilvum_PYR-GCK MNRPYTAQSPYSLTPTERIRSGRASGRRGGGYGGSDVDELDRYGDSDTDA
Mvan_1793|M.vanbaalenii_PYR-1 MNKPYTAQSPYSLTPTERIRSPRG---RYGSYD----DDPDRYGDLDTDA
MSMEG_1932|M.smegmatis_MC2_155 MTRPYSPYDTATTNRHGDHAPEPGSYHGSQGYGYGSGYGRGAYAG-DYQD
TH_1006|M.thermoresistible__bu --------------------------------------------------
MMAR_1348|M.marinum_M MLLRRRRISSRLVDAFEAPHIGLSARTSRSRPADWFITIGSNLARHAIAA
MUL_2531|M.ulcerans_Agy99 ---------------------MATARPPRARLA---------FRRRGQSS
Mb3235|M.bovis_AF2122/97 --------------------MALGAVATAVIIN---------SGDSTST-
Rv3209|M.tuberculosis_H37Rv --------------------MALGAVATAVIIN---------SGDSTST-
MAV_4157|M.avium_104 MGTTLPHLDDRIRGYPDDDADDACDTDPYLNADYNWTGWPADSRWRPATA
MLBr_00813|M.leprae_Br4923 ---------MRLTETTSIRRTTTTSYSGHPIVD----------GRQVAAL
MAB_3529|M.abscessus_ATCC_1997 --MVGYRGDSRYSSDYEPYDDPYNSETAPQSTEYSGLDEDFEYRPPGSNE
Mflv_4674|M.gilvum_PYR-GCK LPPYRDYRPGDHDAHDAYDSDDYTDVENYDEYLDEARIDRRWMWIAG---
Mvan_1793|M.vanbaalenii_PYR-1 LPPF----PG----------DDY-DAEDYDGYIDEERLDRRWMWIAG---
MSMEG_1932|M.smegmatis_MC2_155 YDDYVRADGGNGGFD-----DGY---DDPDIEFYEEPLDRRWIWVAG---
TH_1006|M.thermoresistible__bu --------------------------------------------------
MMAR_1348|M.marinum_M LKRHRRVDTIGPISNSAHTQYDTVRDVEDYPDDESYGGYSDYGYQDSQDD
MUL_2531|M.ulcerans_Agy99 LR-HR-----APLRHQRH--------------------------------
Mb3235|M.bovis_AF2122/97 --------------------------------------------------
Rv3209|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4157|M.avium_104 IVGAVVALGAIATAVIIN--------------------------------
MLBr_00813|M.leprae_Br4923 LG------------------------------------------------
MAB_3529|M.abscessus_ATCC_1997 NWKWVASIAG----------------------------------------
Mflv_4674|M.gilvum_PYR-GCK ------------------------------------VAGAILFVAVITVS
Mvan_1793|M.vanbaalenii_PYR-1 ------------------------------------VAGAILFVAVITAS
MSMEG_1932|M.smegmatis_MC2_155 ------------------------------------VAGAILLVAVICTV
TH_1006|M.thermoresistible__bu --------------------------------------------------
MMAR_1348|M.marinum_M QDEYPDSYADLAWPADRRWRPVAAVLGVVVALGAITTALVINSGDSATTK
MUL_2531|M.ulcerans_Agy99 -------------------------------------------------R
Mb3235|M.bovis_AF2122/97 -------------------------------------------------K
Rv3209|M.tuberculosis_H37Rv -------------------------------------------------K
MAV_4157|M.avium_104 ------------------------------------------SGDSASTK
MLBr_00813|M.leprae_Br4923 ------------------------------------------------SV
MAB_3529|M.abscessus_ATCC_1997 ---------------------------------------AVFAIAVIATA
Mflv_4674|M.gilvum_PYR-GCK MILGGGDSGSVSATVAAPLPTSSAPEPS---AAPSPRAAAPASPSLPAET
Mvan_1793|M.vanbaalenii_PYR-1 MILGGGDSGSVSATVASPLPSSSAPEPS---AAPAPRVAAPAVPSLPAET
MSMEG_1932|M.smegmatis_MC2_155 VILGGGDSGSVSATVADPTQTSQPATTAPQDASSTPRPLPPVAPSLSPET
TH_1006|M.thermoresistible__bu --------------------------------------------------
MMAR_1348|M.marinum_M GKVGVPTPRTVISTTARTTAPSAPPRTAPYPSTSTRPGPGTSASQLPPET
MUL_2531|M.ulcerans_Agy99 GRLPIPAP-------APGQAPALP-----------RPNS-------PPET
Mb3235|M.bovis_AF2122/97 AIVGAPAPRTVISTSPRPTAPTST---------SPHPSPSTLRPQLPPET
Rv3209|M.tuberculosis_H37Rv AIVGAPAPRTVISTSPRPTAPTST---------SPHPSPSTLRPQLPPET
MAV_4157|M.avium_104 ATVGASAPHSVTSAPATTKASVPP---------SASPSPSR---PLPAET
MLBr_00813|M.leprae_Br4923 AALCAIATAVIINSGDNATTKAIVG----------APTPR------PVLT
MAB_3529|M.abscessus_ATCC_1997 VVLSGGNDKPPAAAVTTPVPALTPVTTT----TAPPPPPSATSPAKPSTT
Mflv_4674|M.gilvum_PYR-GCK VTTVTPTAETPAPAPVAPSP--LLPAPQAAP-----PPAAAAPGTVTYRI
Mvan_1793|M.vanbaalenii_PYR-1 VTTVTPTAEIPTPAPTTPAP--LLPAPQAAP-----PPASAAPGTVTYRI
MSMEG_1932|M.smegmatis_MC2_155 VTTVTPSPTAPA-ATAEPAP--VAPPAEAAP-----PPA-VNPRAVTYTV
TH_1006|M.thermoresistible__bu -------------------------------------------------V
MMAR_1348|M.marinum_M FTTVTPPGAAPTWPPTAVAPLPGMQPLPAEP-----PSAALNPRTVIYRV
MUL_2531|M.ulcerans_Agy99 FTTVTPPGAAPTWPPTAVAPLQGMQPLPAEP-----PSAALNPRTVIYRV
Mb3235|M.bovis_AF2122/97 VTTVAPPGTGPTTVPTRTP--TAAPPQTAVP-----PPAPLNPRTVVYRV
Rv3209|M.tuberculosis_H37Rv VTTVAPPGTGPTTVPTRTP--TAAPPQTAVP-----PPAPLNPRTVVYRV
MAV_4157|M.avium_104 FTTVTSPSAAPSVAPSLTPGVAPAQTPTAAPPLAAAPTVTVDPRTVVYSV
MLBr_00813|M.leprae_Br4923 TPSIPLPATPSSTPPLLLLPDTATATIPHKA-----APPALHPRTVVYNV
MAB_3529|M.abscessus_ATCC_1997 TVTSTPAQETPTAEPSTEAP--PPEPPPSNPMLPPEGQRPITPAAFAYYV
:
Mflv_4674|M.gilvum_PYR-GCK TGNRALLDLVTIIYTDEQGALKTDVNAALPWTKTVVLNPGVTLSSVTATS
Mvan_1793|M.vanbaalenii_PYR-1 TGNRALLDLVTVIYTDAQGALQTDVNAALPWSKTIVLNPGVTLSSVTATS
MSMEG_1932|M.smegmatis_MC2_155 TGNRQLIDLVTIVYTDERGALQTDINVALPWTKTVVLDPGVELKSVTATS
TH_1006|M.thermoresistible__bu TGERPLLDVVTVVYTDAQGALQTDVNVALPWSKTIELNPGVELSSVTATS
MMAR_1348|M.marinum_M TGTKQLLDMVNIVYTDARGFPVTEFNVALPWTKMVVLNPGVQTESVVATS
MUL_2531|M.ulcerans_Agy99 TGTKQLLDMVNIVYTDARGFPVTEFNVALPWTKMVVLNPGVQTESVVATS
Mb3235|M.bovis_AF2122/97 TGTKQLFDLVNVVYTDARGFPVTDFNVSLPWTKMVVLNPGVQTESVVATS
Rv3209|M.tuberculosis_H37Rv TGTKQLFDLVNVVYTDARGFPVTDFNVSLPWTKMVVLNPGVQTESVVATS
MAV_4157|M.avium_104 SGSKQLLDLVNVVYTDAHGVPQTEFNVSLPWSKVVVLEPGVQTESVVATS
MLBr_00813|M.leprae_Br4923 TGMKELLDLVTVVYTDARGYPKTEFNVVLPWTKAVVLNLGVKTQSVVATS
MAB_3529|M.abscessus_ATCC_1997 TGNQTPGDLLTITYTDGNGMTRTVLGASLPWTMIVTPSPGITGGSITATS
:* : *::.: *** .* * ... ***: : . *: *:.***
Mflv_4674|M.gilvum_PYR-GCK VSGQLNCAILDANGSLIAVQNNNSIITNCTR
Mvan_1793|M.vanbaalenii_PYR-1 MSGQLNCAILDANGSLIAAQNNNSIITNCTR
MSMEG_1932|M.smegmatis_MC2_155 VAGQLNCSITDAAGNVLVNQANNTMIATCTQ
TH_1006|M.thermoresistible__bu VSSRLNCSITDADGNTLVSHRANTIIATCTR
MMAR_1348|M.marinum_M IYGRLNCAIVNAQGQLVVASTNTSIIATCTR
MUL_2531|M.ulcerans_Agy99 IYGRLNCAIVNAQGQLVVASTNTSIIATCTR
Mb3235|M.bovis_AF2122/97 LYSRLNCSIVNTGAQTVVASTNNAIIATCTR
Rv3209|M.tuberculosis_H37Rv LYSRLNCSIVNTGAQTVVASTNNAIIATCTR
MAV_4157|M.avium_104 FYGRLSCSIFNAAGQRVVASANASNMATCAR
MLBr_00813|M.leprae_Br4923 FHSQLHCSIVNAEGQPVVASTNNAVIATCTR
MAB_3529|M.abscessus_ATCC_1997 FASQVNCSITNSENQMLAVQNSNSIIARCAK
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