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MELGSLIRATNLWGYTDLMRELGADPLPFLRRFDIPPGIEHQEDAFMSLAGFVRMLEASAAELDCPDFGL RLARWQGLGILGPVAVIARNAATLFGGLEAIGRYLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIPYPL QGYELSMANAARMIRLLGGPQARARVFSFRHAQLGTDAAYREALGCTVRFGRTWCGFEVDHRLAGRPIDH ADPETKRIATKYLESQYLPSDATLSERVVGLARRLLPTGQCSAEAIADQLDMHPRTLQRRLAAEGLRCHD LIERERRAQAARYLAQPGLYLSQIAVLLGYSEQSALNRSCRCWFGMTPRQYRAYGGVSGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3109c | virS | - | 100% (340) | virulence-regulating transcriptional regulator VirS |
| M. bovis AF2122 / 97 | Mb3763 | - | 2e-47 | 36.47% (329) | transcriptional regulatory protein AraC/XylS-family |
| M. bovis AF2122 / 97 | Mb1430 | - | 3e-12 | 40.00% (80) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4594 | - | 5e-09 | 36.96% (92) | helix-turn-helix domain-containing protein |
| M. tuberculosis H37Rv | Rv3082c | virS | 0.0 | 99.71% (340) | virulence-regulating transcriptional regulator VirS |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3997c | - | 3e-43 | 34.64% (332) | transcriptional regulatory protein |
| M. marinum M | MMAR_3320 | - | 8e-49 | 35.87% (329) | AraC/XylS family transcriptional regulator |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3718 | - | 9e-09 | 30.39% (181) | PUTATIVE putative aldehyde dehydrogenase |
| M. ulcerans Agy99 | MUL_4350 | - | 3e-47 | 37.46% (331) | AraC/XylS family transcriptional regulator |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3109c|M.bovis_AF2122/97 MELGSLIRATNLWG-------YTDLMRELGADPLPFLRRFDIPPGIEHQE
Rv3082c|M.tuberculosis_H37Rv MELGSLIRATNLWG-------YTDLMRELGADPLPFLRRFDIPPGIEHQE
MMAR_3320|M.marinum_M ---MSVIRGTALTG-------YPALVSELGADPEALLARAGVKRSDVGRF
MUL_4350|M.ulcerans_Agy99 ---MSVVRGTGLSN-------YPNLVSELGGDPAALLRAAGVREQDVGNY
MAB_3997c|M.abscessus_ATCC_199 ---MAVIRGSALTN-------YHELVAELGGDGSRLLAGARVSPTDAGSY
Mflv_4594|M.gilvum_PYR-GCK MDWAQGARSVKFSNAGVPPVAFVQMLESQALDPDAVARLRTIMAREGTDE
TH_3718|M.thermoresistible__bu ------VAAADLID----------TAVEAGIPADRCLRGTWLTRSDLAAA
. : . . . :
Mb3109c|M.bovis_AF2122/97 DAFMS-----LAGFVRMLEASAAELDCP-DFGLRLARWQGLGILGPVAVI
Rv3082c|M.tuberculosis_H37Rv DAFMS-----LAGFVRMLEASAAELDCP-DFGLRLARWQGLGILGPVAVI
MMAR_3320|M.marinum_M DAFIT-----YLALIHAVESAAAVTKTP-DFGRRLAERQGIEILGPVGVA
MUL_4350|M.ulcerans_Agy99 DAFIP-----VRAVIRAIETAAAATGTH-DFGRQLAQRQGIEILGPVGVA
MAB_3997c|M.abscessus_ATCC_199 ERFIS-----LPNGARALEATAAALNAP-DFGRQLARRQGIEILGPVGLA
Mflv_4594|M.gilvum_PYR-GCK ATLMQHDVQAPLRWFRDLYPDLDVDRAT-LLGFSFAGQAQLTSFGPLSVP
TH_3718|M.thermoresistible__bu DRLIT-----AEQELRIVRNVLAATEHPTALAGSAGARYQLPRAGFLGFA
:: : : :. . : * :..
Mb3109c|M.bovis_AF2122/97 ARNAATLFGGLEAIGRYLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIP
Rv3082c|M.tuberculosis_H37Rv ARNAATLFGGLEAIGRYLYVHSPALTLTVSSTTARSNVRFGYEVTEPGIP
MMAR_3320|M.marinum_M ARTSKSVAEALDTFEHYLAAYSPAIAATMSREPGGEASFLEFKILIAHPP
MUL_4350|M.ulcerans_Agy99 ARTAATVADALMIFHTFMAAYSPAIHIEITPLARTQRSVVAIEIVPDDPI
MAB_3997c|M.abscessus_ATCC_199 ARTAATVADAFAILEKFMGAYCPVISARVTDHRDPALCRFEFEYLLNPAP
Mflv_4594|M.gilvum_PYR-GCK LVSAGSVAEIVELLT-YLPLITTAINAQFR--PNDQGLTVGLWGHTGDRA
TH_3718|M.thermoresistible__bu LLSSNTLGDAIRVGIRFWRLTS--VFERVTLEVNRQTTAIVLDDRDVPAD
.: :: . : : . .
Mb3109c|M.bovis_AF2122/97 YPLQGYELSMANAARMIRLLGGPQARARVFSFRHAQLGT-DAAYREALGC
Rv3082c|M.tuberculosis_H37Rv YPLQGYELSMANAARMIRLLGGPQARARVFSFRHAQLGT-DAAYREALGC
MMAR_3320|M.marinum_M AHPQTTELSLGVMLRVLRFLLGAGYAPTVVDLPHPALTP-REDYLRYFAC
MUL_4350|M.ulcerans_Agy99 PCPHTLELALGVSLGVFRLLMGADYTPLAVHLPHDPLTP-PTTYVRYFEC
MAB_3997c|M.abscessus_ATCC_199 PQAQAVELSLGVTLRVLHHFLGAGYRPVSVHLPHQALTP-ASAYQRYFGC
Mflv_4594|M.gilvum_PYR-GCK LDCLAVTYTGSALLRLLDMLVSDALTVTLHLSWSAPVSLNKLAAEMVLAG
TH_3718|M.thermoresistible__bu VRQFLVERDAATMVGVTPALLGGPLPDGVRMSLRRRPNG-DAAVEELVDV
. : : . .
Mb3109c|M.bovis_AF2122/97 TVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSE
Rv3082c|M.tuberculosis_H37Rv TVRFGRTWCGFEVDHRLAGRPIDHADPETKRIATKYLESQYLPSDATLSE
MMAR_3320|M.marinum_M TPRFGSHRGGFRLPSEDLQRPLVRDE-LAHRVVLEYLDTVIDRQRPTMAS
MUL_4350|M.ulcerans_Agy99 TPHFAERRSGFTVRSTDLVRPLHRDE-LAHRAVVDYLSSITPLG-AGIVE
MAB_3997c|M.abscessus_ATCC_199 PPFFCEPVGGFTLRATDMQKALPKDN-LAHQTAVDYLTGTHASRKPDSSQ
Mflv_4594|M.gilvum_PYR-GCK RLFFDAPMSYLHVPVNALNEVCRFSDPLAYRLAVAELRRTLDEQSGATSF
TH_3718|M.thermoresistible__bu S--YGADRNAITFPTALLDRPLAAANPAVAAQCIAQCDELLARHQDEPTV
: : . . : .
Mb3109c|M.bovis_AF2122/97 RVVGLARRLLPTGQC-SAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERE
Rv3082c|M.tuberculosis_H37Rv RVVGLARRLLPTGQC-SAEAIADQLDMHPRTLQRRLAAEGLRCHDLIERE
MMAR_3320|M.marinum_M SIRELIRQLLPTGAA-TVPVIADQFRLHPKALRRRLAAEGTNFNAVVDDV
MUL_4350|M.ulcerans_Agy99 SVRTMARQLLPTGAT-TLEVVAAQFHLHPKTLQRRLADESTTFAALIDEV
MAB_3997c|M.abscessus_ATCC_199 LVRILIRQLLPTGAI-GLGDIALHLGVHPKTLQRRLRAEGMTFAELVDQI
Mflv_4594|M.gilvum_PYR-GCK SKKVRRLLDEDPGQR-SCQRVADELSVSTSTLKRRLAEEGTTFRELRQSC
TH_3718|M.thermoresistible__bu ASRVRRRLARDPGAVPLMRTLATEMGFTERTLRRRLAREGTGYRSLIDEV
.* :* .: . :*:*** *. : :
Mb3109c|M.bovis_AF2122/97 RRAQAARYLAQPGLYLSQIAVLLGYSEQSALNRSCRCWFGMTPRQYRAYG
Rv3082c|M.tuberculosis_H37Rv RRAQAARYLAQPGLYLSQIAVLLGYSEQSALNRSCRRWFGMTPRQYRAYG
MMAR_3320|M.marinum_M RREVTERYLRDSDMTLTHLARQLGYAEQSVLSRSCQRWFGASPASLRAQW
MUL_4350|M.ulcerans_Agy99 RKETADRYLRTTAMSLSHLARELGYAEQSVLTRSCKRWFGIGPAAYRAKT
MAB_3997c|M.abscessus_ATCC_199 RREAAERLLSDTDLSLDHLSRQLGYAEQSVFTRSCKRWFGTTPSAYRSDR
Mflv_4594|M.gilvum_PYR-GCK LRESAMMLLITRSMSASQIATELGYGDLANFSHAFKRWTGRSPSEYRRSQ
TH_3718|M.thermoresistible__bu RGARAADLLSG-GATVKQVAQQLGYSEPAAFHHAFVRWHALPPARFRRAD
: * ::: ***.: : : :: * . * *
Mb3109c|M.bovis_AF2122/97 GVSGR--------
Rv3082c|M.tuberculosis_H37Rv GVSGR--------
MMAR_3320|M.marinum_M QRTASPITLQSTR
MUL_4350|M.ulcerans_Agy99 RVRATPRRR----
MAB_3997c|M.abscessus_ATCC_199 RRA----------
Mflv_4594|M.gilvum_PYR-GCK R------------
TH_3718|M.thermoresistible__bu VR-----------