For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb2903c (mpb53)

annotation: soluble secreted antigen mpb53
coordinates: 3145392 - 3145913
length: 173

MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQGKPAVLWFWT
PWCPFCNAEAPSLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTNLNDADGVIWARYNVPWQPAF
VFYRADGTSTFVNNPTAAMSQDELSGRVAALTS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2903cmpb53-100% (173)soluble secreted antigen mpb53
M. bovis AF2122 / 97Mb1704dsbF2e-3552.82% (142) lipoprotein DsbF

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2864-1e-0726.72% (116) alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal
M. tuberculosis H37RvRv2878cmpt539e-98100.00% (173) soluble secreted antigen MPT53 precursor
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3243-1e-5462.42% (157) soluble secreted antigen MPT53 precursor
M. marinum MMMAR_1831mpt532e-7374.57% (173) soluble secreted antigen Mpt53 precursor
M. avium 104MAV_3729-2e-7278.21% (156) 15 kDa antigen
M. smegmatis MC2 155MSMEG_3543-1e-6878.85% (156) soluble secreted antigen MPT53
M. thermoresistible (build 8)TH_2073mpt537e-6871.35% (171) SOLUBLE SECRETED ANTIGEN MPT53 PRECURSOR
M. ulcerans Agy99MUL_2079mpt532e-7178.34% (157) soluble secreted antigen Mpt53 precursor
M. vanbaalenii PYR-1Mvan_5432-4e-0527.43% (113) redoxin domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2903c|M.bovis_AF2122/97           ------------MSL---RLVSPIKAFADG-IVAVAIAVVLMFG-LANTP
Rv2878c|M.tuberculosis_H37Rv        ------------MSL---RLVSPIKAFADG-IVAVAIAVVLMFG-LANTP
MMAR_1831|M.marinum_M               ------------MTV---RPTPRNRSFAAV-LMASMVALVLTLG-LIAAP
MUL_2079|M.ulcerans_Agy99           --------------------------------MASMVALVLTLG-VIAAP
MAV_3729|M.avium_104                -------------------------------MAATAFAVALLLG-LGDAP
MSMEG_3543|M.smegmatis_MC2_155      ------------MKMGFLRTGATARPGVLGTLSAVVATVVLATA-LVLAP
TH_2073|M.thermoresistible__bu      ------------MKI---RISGTIRFLLLG---AVAA--ALTIA-LAGAP
MAB_3243|M.abscessus_ATCC_1997      ----------MNIQFGGRKKFRAQQVRGLTRTVAVVVAVLLVSAGLVRAP
Mflv_2864|M.gilvum_PYR-GCK          MRSRLRWTVFALVVIAAMAVAIWPRTPQVDGTNTSGPGLTLPAAAVGDAD
Mvan_5432|M.vanbaalenii_PYR-1       ---------MALVIVVALGAALWAELDADESQPRTQRDAISARDRRDADT
                                                                                      

Mb2903c|M.bovis_AF2122/97           R----AVAADERLQFTATTLSGAPFDG-------------------ASLQ
Rv2878c|M.tuberculosis_H37Rv        R----AVAADERLQFTATTLSGAPFDG-------------------ASLQ
MMAR_1831|M.marinum_M               R----ARAADDRLDFTATTLGGAPFNG-------------------ASLQ
MUL_2079|M.ulcerans_Agy99           R----ARAADDRLDFTATTLGGAPFNG-------------------ASLQ
MAV_3729|M.avium_104                R----AAATDDRLQFTATTLSGAPFNG-------------------ASLQ
MSMEG_3543|M.smegmatis_MC2_155      -----SAVADDRLQFTGTTLSGASFDG-------------------SSLA
TH_2073|M.thermoresistible__bu      -----TAVADDRLQFTGTTLSGTPFDG-------------------ASLA
MAB_3243|M.abscessus_ATCC_1997      -----SARADGLLDFTGTTVSGAPFNG-------------------ASLK
Mflv_2864|M.gilvum_PYR-GCK          TGELARLTARAALAPCPTPREGAPPKGDLAGALASCLGARTMFDVGAALA
Mvan_5432|M.vanbaalenii_PYR-1       PEALAGLRARAALEPCPTGGDAGPGPETLRGIELECVGDGSRVDVAEAVA
                                            :   *    *   . .                       :: 

Mb2903c|M.bovis_AF2122/97           GKPAVLWFWTPWCPFCNAEAPSLSQVAA-ANPAVTFVGIATRADVGAMQS
Rv2878c|M.tuberculosis_H37Rv        GKPAVLWFWTPWCPFCNAEAPSLSQVAA-ANPAVTFVGIATRADVGAMQS
MMAR_1831|M.marinum_M               GKPAVLWFWTPWCPFCNAEGPAASQVAA-ANPGVTFVGIAAHSDVGAMQG
MUL_2079|M.ulcerans_Agy99           GKPAVLWFWTPWCPFCNAEGPAASQVAA-ANPGVTFVGIAAHSDVGAMQG
MAV_3729|M.avium_104                GKPAVLWFWTPWCPYCNAEAPGVSRVAA-ANPGVTFVGVAAHSDVGAMAN
MSMEG_3543|M.smegmatis_MC2_155      GKPAVLWFWTPWCPFCNAEAPSVGQVAA-ANPEVTFVGVAARSDVAAMQG
TH_2073|M.thermoresistible__bu      GRPAVLWFWTPWCPFCNAEAPNVSRVAA-ANPDVTFVGVAARADVAAMQD
MAB_3243|M.abscessus_ATCC_1997      GKPVVLWFWAAYCPFCNGEGPHVSAVSA-ANPRVTFVGISGRGSVGEMEA
Mflv_2864|M.gilvum_PYR-GCK          GEQTLINLWASWCAPCREEIPVLDAYAG-QPGAVRVVGMNVQDTDTVALS
Mvan_5432|M.vanbaalenii_PYR-1       GRPVVLNLWAYWCGPCADELPAMAEYQRRVGSAVTVLTVHQDENESAALL
                                    *. .:: :*: :*  *  * *            * .: :           

Mb2903c|M.bovis_AF2122/97           FVSKYNLNFTNLNDADGVIWARYNVP-WQPAFVFYRADGTSTFVNNPTAA
Rv2878c|M.tuberculosis_H37Rv        FVSKYNLNFTNLNDADGVIWARYNVP-WQPAFVFYRADGTSTFVNNPTAA
MMAR_1831|M.marinum_M               FVSKYGLNFTNINDADGAIWARYNVP-WQPAWVFYRADGSSTFVNNPTSA
MUL_2079|M.ulcerans_Agy99           FVSKYGLNFTNINDADGAIWARYNVP-WQPAWVFYRVDGSSTFVNNPTSA
MAV_3729|M.avium_104                FVSKYNLNFTTLNDADGAIWARYGVP-WQPAYVFYRADGSSTFVNNPTSA
MSMEG_3543|M.smegmatis_MC2_155      FVDKYNLNFTNLNDADGSIWARYNVP-WQPAYVFYRADGSSTFVNNPTSA
TH_2073|M.thermoresistible__bu      FVNTYNLDFTNLNDADGSIWARYNVP-WQPAYVFYRADGSSSFVNNPTAA
MAB_3243|M.abscessus_ATCC_1997      FISRYNLHFTNLNDADGSLWRQFGVP-WQPAYLFINSNGTSDFVNNPTSS
Mflv_2864|M.gilvum_PYR-GCK          LLADLGVHYPSFGNADAVGQVLGAPP-VLPLSYLVGTDGTVRRVTTPTVF
Mvan_5432|M.vanbaalenii_PYR-1       RLTELGVHLPTLQDGRRTIAAALQVPNVMPATVVLRADGSVAEIL-PRSF
                                     :   .:. ..: :.          *   *   .   :*:   :  *   

Mb2903c|M.bovis_AF2122/97           MSQDELSGRVAALTS--
Rv2878c|M.tuberculosis_H37Rv        MSQDELSGRVAALTS--
MMAR_1831|M.marinum_M               MSQQELADRVAALTS--
MUL_2079|M.ulcerans_Agy99           MSQQELADRVAALTS--
MAV_3729|M.avium_104                MPQDELAARVAALR---
MSMEG_3543|M.smegmatis_MC2_155      MSKQELSDRVAALNS--
TH_2073|M.thermoresistible__bu      MSEAELADRVAALKN--
MAB_3243|M.abscessus_ATCC_1997      MSEQELSDRVKALT---
Mflv_2864|M.gilvum_PYR-GCK          RDVEQVRAAVAAMNP--
Mvan_5432|M.vanbaalenii_PYR-1       ATADEIAAAVDPKIGAA
                                        ::   * .