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M. thermoresistible (build 8) TH_2073 (mpt53)

annotation: SOLUBLE SECRETED ANTIGEN MPT53 PRECURSOR
coordinates: 4056419 - 4056925
length: 169

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2073mpt53-100% (169)SOLUBLE SECRETED ANTIGEN MPT53 PRECURSOR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2903cmpb537e-6871.35% (171) soluble secreted antigen mpb53
M. gilvum PYR-GCKMflv_1374-9e-0633.66% (101) alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal
M. tuberculosis H37RvRv2878cmpt537e-6871.35% (171) soluble secreted antigen MPT53 precursor
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3243-6e-5456.44% (163) soluble secreted antigen MPT53 precursor
M. marinum MMMAR_1831mpt539e-6673.72% (156) soluble secreted antigen Mpt53 precursor
M. avium 104MAV_3729-7e-6676.47% (153) 15 kDa antigen
M. smegmatis MC2 155MSMEG_3543-4e-7275.44% (171) soluble secreted antigen MPT53
M. ulcerans Agy99MUL_2079mpt531e-6474.17% (151) soluble secreted antigen Mpt53 precursor
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


TH_2073|M.thermoresistible__bu      ------------------------MKI---RISGTIRFLLLG---AVAA-
MSMEG_3543|M.smegmatis_MC2_155      ------------------------MKMGFLRTGATARPGVLGTLSAVVAT
MMAR_1831|M.marinum_M               ------------------------MTV---RPTPRNRSFAAV-LMASMVA
MUL_2079|M.ulcerans_Agy99           --------------------------------------------MASMVA
MAV_3729|M.avium_104                -------------------------------------------MAATAFA
Mb2903c|M.bovis_AF2122/97           ------------------------MSL---RLVSPIKAFADG-IVAVAIA
Rv2878c|M.tuberculosis_H37Rv        ------------------------MSL---RLVSPIKAFADG-IVAVAIA
MAB_3243|M.abscessus_ATCC_1997      ----------------------MNIQFGGRKKFRAQQVRGLTRTVAVVVA
Mflv_1374|M.gilvum_PYR-GCK          MALVILVALGVAFWSELDAQDPASPAGNDARDTVSARDKRDADTPEALAG
                                                                                      

TH_2073|M.thermoresistible__bu      -ALTIA-LAGAP-TAVADDRLQFTGTTLS----GTPFD-GASLAGRPAVL
MSMEG_3543|M.smegmatis_MC2_155      VVLATA-LVLAP-SAVADDRLQFTGTTLS----GASFD-GSSLAGKPAVL
MMAR_1831|M.marinum_M               LVLTLG-LIAAPRARAADDRLDFTATTLG----GAPFN-GASLQGKPAVL
MUL_2079|M.ulcerans_Agy99           LVLTLG-VIAAPRARAADDRLDFTATTLG----GAPFN-GASLQGKPAVL
MAV_3729|M.avium_104                VALLLG-LGDAPRAAATDDRLQFTATTLS----GAPFN-GASLQGKPAVL
Mb2903c|M.bovis_AF2122/97           VVLMFG-LANTPRAVAADERLQFTATTLS----GAPFD-GASLQGKPAVL
Rv2878c|M.tuberculosis_H37Rv        VVLMFG-LANTPRAVAADERLQFTATTLS----GAPFD-GASLQGKPAVL
MAB_3243|M.abscessus_ATCC_1997      VLLVSAGLVRAP-SARADGLLDFTGTTVS----GAPFN-GASLKGKPVVL
Mflv_1374|M.gilvum_PYR-GCK          LRAAAG-LEPCPAPGEGQGPAPLRGIVLECVGDGAPTDIAAAVAGRPVVL
                                         . :   * .   :    : . .:     *:. : .::: *:*.**

TH_2073|M.thermoresistible__bu      WFWTPWCPFCNAEAPNVSRVAAAN-PDVTFVGVAARADVAAMQDFVNTYN
MSMEG_3543|M.smegmatis_MC2_155      WFWTPWCPFCNAEAPSVGQVAAAN-PEVTFVGVAARSDVAAMQGFVDKYN
MMAR_1831|M.marinum_M               WFWTPWCPFCNAEGPAASQVAAAN-PGVTFVGIAAHSDVGAMQGFVSKYG
MUL_2079|M.ulcerans_Agy99           WFWTPWCPFCNAEGPAASQVAAAN-PGVTFVGIAAHSDVGAMQGFVSKYG
MAV_3729|M.avium_104                WFWTPWCPYCNAEAPGVSRVAAAN-PGVTFVGVAAHSDVGAMANFVSKYN
Mb2903c|M.bovis_AF2122/97           WFWTPWCPFCNAEAPSLSQVAAAN-PAVTFVGIATRADVGAMQSFVSKYN
Rv2878c|M.tuberculosis_H37Rv        WFWTPWCPFCNAEAPSLSQVAAAN-PAVTFVGIATRADVGAMQSFVSKYN
MAB_3243|M.abscessus_ATCC_1997      WFWAAYCPFCNGEGPHVSAVSAAN-PRVTFVGISGRGSVGEMEAFISRYN
Mflv_1374|M.gilvum_PYR-GCK          NLWAYWCGPCADELPAMAEYQRRVGPEVLVLTVHQDENESAALIRLAELG
                                     :*: :*  *  * *  .       * * .: :    . .     :   .

TH_2073|M.thermoresistible__bu      LDFTNLNDADGSIWARYNVP-WQPAYVFYRADGSSSFVNNPTAAMSEAEL
MSMEG_3543|M.smegmatis_MC2_155      LNFTNLNDADGSIWARYNVP-WQPAYVFYRADGSSTFVNNPTSAMSKQEL
MMAR_1831|M.marinum_M               LNFTNINDADGAIWARYNVP-WQPAWVFYRADGSSTFVNNPTSAMSQQEL
MUL_2079|M.ulcerans_Agy99           LNFTNINDADGAIWARYNVP-WQPAWVFYRVDGSSTFVNNPTSAMSQQEL
MAV_3729|M.avium_104                LNFTTLNDADGAIWARYGVP-WQPAYVFYRADGSSTFVNNPTSAMPQDEL
Mb2903c|M.bovis_AF2122/97           LNFTNLNDADGVIWARYNVP-WQPAFVFYRADGTSTFVNNPTAAMSQDEL
Rv2878c|M.tuberculosis_H37Rv        LNFTNLNDADGVIWARYNVP-WQPAFVFYRADGTSTFVNNPTAAMSQDEL
MAB_3243|M.abscessus_ATCC_1997      LHFTNLNDADGSLWRQFGVP-WQPAYLFINSNGTSDFVNNPTSSMSEQEL
Mflv_1374|M.gilvum_PYR-GCK          VHLPTVQDGRRSIAAALQVPNVMPATVVLRADGSVAEIL-PRSFATADDI
                                    :.:..::*.   :     **   ** :. . :*:   :  * :  .  ::

TH_2073|M.thermoresistible__bu      ADRVAALKN--
MSMEG_3543|M.smegmatis_MC2_155      SDRVAALNS--
MMAR_1831|M.marinum_M               ADRVAALTS--
MUL_2079|M.ulcerans_Agy99           ADRVAALTS--
MAV_3729|M.avium_104                AARVAALR---
Mb2903c|M.bovis_AF2122/97           SGRVAALTS--
Rv2878c|M.tuberculosis_H37Rv        SGRVAALTS--
MAB_3243|M.abscessus_ATCC_1997      SDRVKALT---
Mflv_1374|M.gilvum_PYR-GCK          AAAVDPKIGVA
                                    :  * .