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M. bovis AF2122 / 97 Mb2730 (ideR)

annotation: IRON-dependent repressor and activator IDER
coordinates: 2980201 - 2980893
length: 230

MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMERDGLLRVAGDRHLELTEKGRA
LAIAVMRKHRLAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLVELGV
GPEPGADDANLVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETTPGGGVTIVIP
GHENVTLPHEMAHAVKVEKV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2730ideR-100% (230)IRON-dependent repressor and activator IDER
M. bovis AF2122 / 97Mb2811sirR1e-1630.65% (186) transcriptional repressor SIRR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3949-1e-11187.83% (230) iron dependent repressor
M. tuberculosis H37RvRv2711ideR1e-130100.00% (230) IRON-dependent repressor and activator IDER
M. leprae Br4923MLBr_01013-1e-11890.00% (230) iron dependent repressor
M. abscessus ATCC 19977MAB_3029-1e-10581.74% (230) Iron-dependent repressor IdeR
M. marinum MMMAR_2002ideR1e-12192.61% (230) iron-dependent repressor and activator IdeR
M. avium 104MAV_3604-1e-12193.48% (230) iron-dependent repressor IdeR
M. smegmatis MC2 155MSMEG_2750-1e-11186.52% (230) iron-dependent repressor IdeR
M. thermoresistible (build 8)TH_1487ideR1e-11086.15% (231) IRON-DEPENDENT REPRESSOR AND ACTIVATOR IDER
M. ulcerans Agy99MUL_3351ideR1e-12192.17% (230) iron-dependent repressor and activator IdeR
M. vanbaalenii PYR-1Mvan_2450-1e-11188.26% (230) iron dependent repressor

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3949|M.gilvum_PYR-GCK          MNDLVDTTEMYLRTIYDLEEECVIPLRARIAERLDQSGPTVSQTVSRMER
Mvan_2450|M.vanbaalenii_PYR-1       MNDLVDTTEMYLRTIYDLEEEGVIPLRARIAERLDQSGPTVSQTVSRMER
MSMEG_2750|M.smegmatis_MC2_155      MNDLVDTTEMYLRTIYDLEEEGVVPLRARIAERLDQSGPTVSQTVSRMER
TH_1487|M.thermoresistible__bu      MNDLVDTTEMYLRTIYDLEEEGVVPLRARIAERLEQSGPTVSQTVSRMER
Mb2730|M.bovis_AF2122/97            MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMER
Rv2711|M.tuberculosis_H37Rv         MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMER
MMAR_2002|M.marinum_M               MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMER
MUL_3351|M.ulcerans_Agy99           MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMER
MAV_3604|M.avium_104                MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMER
MLBr_01013|M.leprae_Br4923          MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMER
MAB_3029|M.abscessus_ATCC_1997      MNDLVDTTEMYLRTIYDLEEEGVVPLRARIAERLEQSGPTVSQTVARMER
                                    **:****************** * **********:**********:****

Mflv_3949|M.gilvum_PYR-GCK          DGLLHVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
Mvan_2450|M.vanbaalenii_PYR-1       DGLLHVAGDRHLELTEKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
MSMEG_2750|M.smegmatis_MC2_155      DGLLHVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEDVHAE
TH_1487|M.thermoresistible__bu      DGLLQVAGDRHLELTEKGRALAISVMRKHRLAERLLVDVIGLPWEEVHAE
Mb2730|M.bovis_AF2122/97            DGLLRVAGDRHLELTEKGRALAIAVMRKHRLAERLLVDVIGLPWEEVHAE
Rv2711|M.tuberculosis_H37Rv         DGLLRVAGDRHLELTEKGRALAIAVMRKHRLAERLLVDVIGLPWEEVHAE
MMAR_2002|M.marinum_M               DGLLRVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
MUL_3351|M.ulcerans_Agy99           DGLLRVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
MAV_3604|M.avium_104                DGLLHVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
MLBr_01013|M.leprae_Br4923          DGLLRVAGNRHLELTTKGRAMAIAVMRKHRLAERLLVDVIGLPWEEVHAE
MAB_3029|M.abscessus_ATCC_1997      DGLLNVAGDRHLELTDKGRALAVSVMRKHRLAECLLVDIIGLPWEDVHAE
                                    ****.***:****** ****:*::********* ****:******:****

Mflv_3949|M.gilvum_PYR-GCK          ACRWEHVMSVDVERRLVQVLNNPTTSPFGNPIPGLSELGVGDESG-EAMS
Mvan_2450|M.vanbaalenii_PYR-1       ACRWEHVMSVDVERRLVQVLNNPTTSPFGNPIPGLSELGVGDEIN-ETFS
MSMEG_2750|M.smegmatis_MC2_155      ACRWEHVMSEEVERRLVQVLDNPTTSPFGNPIPGLTELGVTPGVNTEDVS
TH_1487|M.thermoresistible__bu      ACRWEHVMSEDVERRLVKVLDNPTTSPFGNPIPGLSELGVVSTEP-EDMN
Mb2730|M.bovis_AF2122/97            ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLVELGVGPEPGADDAN
Rv2711|M.tuberculosis_H37Rv         ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLVELGVGPEPGADDAN
MMAR_2002|M.marinum_M               ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLLDLGVGPESDSYEAN
MUL_3351|M.ulcerans_Agy99           ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLLDLGVGPESDSYEAN
MAV_3604|M.avium_104                ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLLDLGVGPESGAEEAN
MLBr_01013|M.leprae_Br4923          ACRWEHVMSEDVERRLIKVLNNPTTSPFGNPIPGLLDLGAGPDASAANAK
MAB_3029|M.abscessus_ATCC_1997      ACRWEHVMSEDVERRLLTVLNNPTTSPFGNPIPGLSELGVPADRS-ESAS
                                    ********* :*****: **:************** :**.         .

Mflv_3949|M.gilvum_PYR-GCK          LVRLTELPAGMPVAVVVRQLTEHVQGDVELIARLKDAGVVPNARVTVENN
Mvan_2450|M.vanbaalenii_PYR-1       MVRLTELPAGMPVAVVVRQLTEHVQGDAELIARLKDAGVVPNARVTVEVK
MSMEG_2750|M.smegmatis_MC2_155      LVRLTELPVGMPVAVVVRQLTEHVQGDTDLIGRLKEAGVVPNARVTVEAN
TH_1487|M.thermoresistible__bu      LVRLTELPAGTPVPVVVRQLTEHVQGDVELITRLKEAGVVPNARVTVQVN
Mb2730|M.bovis_AF2122/97            LVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETT
Rv2711|M.tuberculosis_H37Rv         LVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETT
MMAR_2002|M.marinum_M               LVRLTELPSGSPVAVVVRQLTEHVQGDIDLISRLKDAGVVPNARVTVETS
MUL_3351|M.ulcerans_Agy99           LVRLTELPSGSPVAVVVRQLTEHVQGDIDLISRLKDAGVVPNARVTVETS
MAV_3604|M.avium_104                LVRLTELPSGAPVAVVVRQLTEHVQGDIDLISRLKDAGVVPNARVTVETG
MLBr_01013|M.leprae_Br4923          LVRLTELPSGSPVAVVVRQLTEHVQDDIDLITRLKDTGVVPNARVTVETS
MAB_3029|M.abscessus_ATCC_1997      AVRLTEIPSGSQVAVVVRRLAEHVQADTDLLSRLKDAGVVPNARVTVESS
                                     *****:* *  *.****:*:**** * :*: ***::**********:  

Mflv_3949|M.gilvum_PYR-GCK          DHGGVMIVIPGHEQVELPHEMAHAVRVEKV
Mvan_2450|M.vanbaalenii_PYR-1       DHGGVMIVIPGHEQVELPHEMAHAVKVEKV
MSMEG_2750|M.smegmatis_MC2_155      NNGGVMIVIPGHEQVELPHHMAHAVKVEKV
TH_1487|M.thermoresistible__bu      ENKSVSIIIPGHEQVDLPYQMAHAVKVEKV
Mb2730|M.bovis_AF2122/97            PGGGVTIVIPGHENVTLPHEMAHAVKVEKV
Rv2711|M.tuberculosis_H37Rv         PGGGVTIVIPGHENVTLPHEMAHAVKVEKV
MMAR_2002|M.marinum_M               PAGGVTILIPGHENVTLPHAMAHAVKVEKV
MUL_3351|M.ulcerans_Agy99           PAGGVTILIPGHENVTLPHAMAYAVKVEKV
MAV_3604|M.avium_104                PAG-VTIVIPGHENVTLPHEMAHAVKVEKV
MLBr_01013|M.leprae_Br4923          PAGNVIIIIPGHENVTLPHEMAHAVKVEKV
MAB_3029|M.abscessus_ATCC_1997      PDG-VIIIIPGHESVELPHEMAHAVMVEKV
                                        * *:*****.* **: **:** ****