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M. leprae Br4923 MLBr_01013 (-)

annotation: iron dependent repressor
coordinates: 1183521 - 1184213
length: 230

NDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMERDGLLRVAGNRHLELTTKGRAM
AIAVMRKHRLAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLIKVLNNPTTSPFGNPIPGLLDLGAG
PDASAANAKLVRLTELPSGSPVAVVVRQLTEHVQDDIDLITRLKDTGVVPNARVTVETSPAGNVIIIIPG
HENVTLPHEMAHAVKVEKV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01013--100% (230)iron dependent repressor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2730ideR1e-11890.00% (230) IRON-dependent repressor and activator IDER
M. gilvum PYR-GCKMflv_3949-1e-10783.48% (230) iron dependent repressor
M. tuberculosis H37RvRv2711ideR1e-11890.00% (230) IRON-dependent repressor and activator IDER
M. abscessus ATCC 19977MAB_3029-1e-10482.61% (230) Iron-dependent repressor IdeR
M. marinum MMMAR_2002ideR1e-11991.30% (230) iron-dependent repressor and activator IdeR
M. avium 104MAV_3604-1e-11790.43% (230) iron-dependent repressor IdeR
M. smegmatis MC2 155MSMEG_2750-1e-10682.17% (230) iron-dependent repressor IdeR
M. thermoresistible (build 8)TH_1487ideR1e-10582.17% (230) IRON-DEPENDENT REPRESSOR AND ACTIVATOR IDER
M. ulcerans Agy99MUL_3351ideR1e-11890.87% (230) iron-dependent repressor and activator IdeR
M. vanbaalenii PYR-1Mvan_2450-1e-10683.48% (230) iron dependent repressor

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3949|M.gilvum_PYR-GCK          MNDLVDTTEMYLRTIYDLEEECVIPLRARIAERLDQSGPTVSQTVSRMER
Mvan_2450|M.vanbaalenii_PYR-1       MNDLVDTTEMYLRTIYDLEEEGVIPLRARIAERLDQSGPTVSQTVSRMER
MSMEG_2750|M.smegmatis_MC2_155      MNDLVDTTEMYLRTIYDLEEEGVVPLRARIAERLDQSGPTVSQTVSRMER
TH_1487|M.thermoresistible__bu      MNDLVDTTEMYLRTIYDLEEEGVVPLRARIAERLEQSGPTVSQTVSRMER
MMAR_2002|M.marinum_M               MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMER
MUL_3351|M.ulcerans_Agy99           MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMER
MAV_3604|M.avium_104                MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMER
Mb2730|M.bovis_AF2122/97            MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMER
Rv2711|M.tuberculosis_H37Rv         MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMER
MLBr_01013|M.leprae_Br4923          MNDLVDTTEMYLRTIYDLEEEGVTPLRARIAERLEQSGPTVSQTVSRMER
MAB_3029|M.abscessus_ATCC_1997      MNDLVDTTEMYLRTIYDLEEEGVVPLRARIAERLEQSGPTVSQTVARMER
                                    **:****************** * **********:**********:****

Mflv_3949|M.gilvum_PYR-GCK          DGLLHVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
Mvan_2450|M.vanbaalenii_PYR-1       DGLLHVAGDRHLELTEKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
MSMEG_2750|M.smegmatis_MC2_155      DGLLHVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEDVHAE
TH_1487|M.thermoresistible__bu      DGLLQVAGDRHLELTEKGRALAISVMRKHRLAERLLVDVIGLPWEEVHAE
MMAR_2002|M.marinum_M               DGLLRVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
MUL_3351|M.ulcerans_Agy99           DGLLRVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
MAV_3604|M.avium_104                DGLLHVAGDRHLELTDKGRALAVAVMRKHRLAERLLVDVIGLPWEEVHAE
Mb2730|M.bovis_AF2122/97            DGLLRVAGDRHLELTEKGRALAIAVMRKHRLAERLLVDVIGLPWEEVHAE
Rv2711|M.tuberculosis_H37Rv         DGLLRVAGDRHLELTEKGRALAIAVMRKHRLAERLLVDVIGLPWEEVHAE
MLBr_01013|M.leprae_Br4923          DGLLRVAGNRHLELTTKGRAMAIAVMRKHRLAERLLVDVIGLPWEEVHAE
MAB_3029|M.abscessus_ATCC_1997      DGLLNVAGDRHLELTDKGRALAVSVMRKHRLAECLLVDIIGLPWEDVHAE
                                    ****.***:****** ****:*::********* ****:******:****

Mflv_3949|M.gilvum_PYR-GCK          ACRWEHVMSVDVERRLVQVLNNPTTSPFGNPIPGLSELGVGDESG-EAMS
Mvan_2450|M.vanbaalenii_PYR-1       ACRWEHVMSVDVERRLVQVLNNPTTSPFGNPIPGLSELGVGDEIN-ETFS
MSMEG_2750|M.smegmatis_MC2_155      ACRWEHVMSEEVERRLVQVLDNPTTSPFGNPIPGLTELGVTPGVNTEDVS
TH_1487|M.thermoresistible__bu      ACRWEHVMSEDVERRLVKVLDNPTTSPFGNPIPGLSELGVVSTEP-EDMN
MMAR_2002|M.marinum_M               ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLLDLGVGPESDSYEAN
MUL_3351|M.ulcerans_Agy99           ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLLDLGVGPESDSYEAN
MAV_3604|M.avium_104                ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLLDLGVGPESGAEEAN
Mb2730|M.bovis_AF2122/97            ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLVELGVGPEPGADDAN
Rv2711|M.tuberculosis_H37Rv         ACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLVELGVGPEPGADDAN
MLBr_01013|M.leprae_Br4923          ACRWEHVMSEDVERRLIKVLNNPTTSPFGNPIPGLLDLGAGPDASAANAK
MAB_3029|M.abscessus_ATCC_1997      ACRWEHVMSEDVERRLLTVLNNPTTSPFGNPIPGLSELGVPADRS-ESAS
                                    ********* :*****: **:************** :**.         .

Mflv_3949|M.gilvum_PYR-GCK          LVRLTELPAGMPVAVVVRQLTEHVQGDVELIARLKDAGVVPNARVTVENN
Mvan_2450|M.vanbaalenii_PYR-1       MVRLTELPAGMPVAVVVRQLTEHVQGDAELIARLKDAGVVPNARVTVEVK
MSMEG_2750|M.smegmatis_MC2_155      LVRLTELPVGMPVAVVVRQLTEHVQGDTDLIGRLKEAGVVPNARVTVEAN
TH_1487|M.thermoresistible__bu      LVRLTELPAGTPVPVVVRQLTEHVQGDVELITRLKEAGVVPNARVTVQVN
MMAR_2002|M.marinum_M               LVRLTELPSGSPVAVVVRQLTEHVQGDIDLISRLKDAGVVPNARVTVETS
MUL_3351|M.ulcerans_Agy99           LVRLTELPSGSPVAVVVRQLTEHVQGDIDLISRLKDAGVVPNARVTVETS
MAV_3604|M.avium_104                LVRLTELPSGAPVAVVVRQLTEHVQGDIDLISRLKDAGVVPNARVTVETG
Mb2730|M.bovis_AF2122/97            LVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETT
Rv2711|M.tuberculosis_H37Rv         LVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETT
MLBr_01013|M.leprae_Br4923          LVRLTELPSGSPVAVVVRQLTEHVQDDIDLITRLKDTGVVPNARVTVETS
MAB_3029|M.abscessus_ATCC_1997      AVRLTEIPSGSQVAVVVRRLAEHVQADTDLLSRLKDAGVVPNARVTVESS
                                     *****:* *  *.****:*:**** * :*: ***::**********:  

Mflv_3949|M.gilvum_PYR-GCK          DHGGVMIVIPGHEQVELPHEMAHAVRVEKV
Mvan_2450|M.vanbaalenii_PYR-1       DHGGVMIVIPGHEQVELPHEMAHAVKVEKV
MSMEG_2750|M.smegmatis_MC2_155      NNGGVMIVIPGHEQVELPHHMAHAVKVEKV
TH_1487|M.thermoresistible__bu      ENKSVSIIIPGHEQVDLPYQMAHAVKVEKV
MMAR_2002|M.marinum_M               PAGGVTILIPGHENVTLPHAMAHAVKVEKV
MUL_3351|M.ulcerans_Agy99           PAGGVTILIPGHENVTLPHAMAYAVKVEKV
MAV_3604|M.avium_104                PAG-VTIVIPGHENVTLPHEMAHAVKVEKV
Mb2730|M.bovis_AF2122/97            PGGGVTIVIPGHENVTLPHEMAHAVKVEKV
Rv2711|M.tuberculosis_H37Rv         PGGGVTIVIPGHENVTLPHEMAHAVKVEKV
MLBr_01013|M.leprae_Br4923          PAGNVIIIIPGHENVTLPHEMAHAVKVEKV
MAB_3029|M.abscessus_ATCC_1997      PDG-VIIIIPGHESVELPHEMAHAVMVEKV
                                        * *:*****.* **: **:** ****