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MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFPMGKLFAGACVVWFFVLFDML DGAMARERGGGTRFGAVLDATCDRISDGAVFCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEA SGLRGDGGFIERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVWTSPGAIDRMA IPGKGDR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2644c | pgsA1 | - | 100% (217) | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| M. bovis AF2122 / 97 | Mb2767c | pgsA3 | 1e-05 | 27.82% (133) | CDP-diacylglycerol--glycerol-3-phosphate |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3836 | - | 4e-80 | 67.76% (214) | CDP-alcohol phosphatidyltransferase |
| M. tuberculosis H37Rv | Rv2612c | pgsA1 | 1e-124 | 100.00% (217) | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| M. leprae Br4923 | MLBr_00454 | pgsA | 7e-96 | 79.34% (213) | putative phosphatidyltransferase |
| M. abscessus ATCC 19977 | MAB_2896c | - | 1e-74 | 68.66% (201) | phosphatidylinositol synthase PgsA |
| M. marinum M | MMAR_2090 | pgsA1 | 1e-104 | 87.92% (207) | pi synthase PgsA1 |
| M. avium 104 | MAV_3488 | - | 4e-92 | 78.85% (208) | CDP-alcohol phosphatidyltransferase |
| M. smegmatis MC2 155 | MSMEG_2933 | - | 4e-80 | 66.82% (217) | phosphatidylinositol synthase |
| M. thermoresistible (build 8) | TH_0577 | pgsA3 | 2e-05 | 27.21% (136) | PROBABLE PGP SYNTHASE PGSA3 |
| M. ulcerans Agy99 | MUL_3254 | pgsA1 | 1e-103 | 87.44% (207) | pi synthase PgsA1 |
| M. vanbaalenii PYR-1 | Mvan_2560 | - | 3e-80 | 66.36% (217) | CDP-alcohol phosphatidyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2644c|M.bovis_AF2122/97 MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFP
Rv2612c|M.tuberculosis_H37Rv MSKLPFLSRAAFARITTPIARGLLRVGLTPDVVTILGTTASVAGALTLFP
MMAR_2090|M.marinum_M MSKAPFLSRAAFARVTNPLARGLLRIGLTPDAVTIIGTTASVAGALVLFP
MUL_3254|M.ulcerans_Agy99 MSKAPFLSRAAFARVTNPLARGLLRIGLTPDAVTIIGTTASVAGALVLFP
MLBr_00454|M.leprae_Br4923 MSKVPFLSRATFTRLTTPTARALLRVGLTPDAITVLGTIVAASGALVLFP
MAV_3488|M.avium_104 MSKVPFLSRAAFARLTTPTARACLRLGLTPDVVTVAGTIVAVAGALILFP
Mflv_3836|M.gilvum_PYR-GCK MSNFYLMTRAAYAKLSRPVAKGALKVGLTPDTVTILGTAGSVLAALTLFP
Mvan_2560|M.vanbaalenii_PYR-1 MSDFYLMTRAAYVKLSRPVARGALKLGLSPDSVTILGTAGSVLGALTLFP
MSMEG_2933|M.smegmatis_MC2_155 MSNVYLMTRAAYVKLSRPVAKAALRAGLTPDIVTLAGTAAAVIGALTLFP
MAB_2896c|M.abscessus_ATCC_199 MSG--LLSRETFAKITNPLASALLRAGFTPDTVTIFGTAASVVAALTLFP
TH_0577|M.thermoresistible__bu -----------VANLANALTG--VRLLLVPVFLILLFVG---DGHETSWR
..:: . : :: : * : : . . :
Mb2644c|M.bovis_AF2122/97 MGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAV
Rv2612c|M.tuberculosis_H37Rv MGKLFAGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRISDGAV
MMAR_2090|M.marinum_M MGKLFPGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDAACDRISDGAV
MUL_3254|M.ulcerans_Agy99 MGKLFPGACVVWFFVLFDMLDGAMARERGGGTRFGAVLDAACDRISDGAV
MLBr_00454|M.leprae_Br4923 IGKLFAGTLVVWFFVLFDMLDGAMARERGGGTRYGAVLDATCDRISDGAV
MAV_3488|M.avium_104 IGELFVGTLVVWFFVLFDMLDGAMARERGGGTRFGAVLDATCDRVSDGAV
Mflv_3836|M.gilvum_PYR-GCK IGQLWWGAVAVSFFVLADMLDGAMARERGGGTRFGAVLDAACDRISDGAV
Mvan_2560|M.vanbaalenii_PYR-1 IGQLFAGAWVVAFFVLADMLDGAMARQSGGGTRFGAVLDATCDRISDGAV
MSMEG_2933|M.smegmatis_MC2_155 IGQLWWGAVVVSFFVLADMLDGAMAREQGGGTRFGAVLDATCDRLGDGAV
MAB_2896c|M.abscessus_ATCC_199 TGHLFWGGMAVWLFAMFDMLDGAMARARGGGTRFGAVLDATCDRVADGAV
TH_0577|M.thermoresistible__bu IG----AFAVFAVAVITDRFDGALARSYGMVTEFGTLADPIADKALIGAA
* . .. . .: * :***:** * *.:*:: *. .*: **.
Mb2644c|M.bovis_AF2122/97 FCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFI
Rv2612c|M.tuberculosis_H37Rv FCGLLWWIAFHMRDRPLVIATLICLVTSQVISYIKARAEASGLRGDGGFI
MMAR_2090|M.marinum_M FGGLLWWVAFGMRDRLLVVATLICLVTSQVISYIKARAEASGLRGDGGII
MUL_3254|M.ulcerans_Agy99 FSGLLWWVAFGMRDRLLVVATLICLVISQVISYIKARAEASGLRGDGGII
MLBr_00454|M.leprae_Br4923 FCGLLWWMAFGLHSKHLVVATLICLVTSQVISYIKARAEASGLRGDDGLI
MAV_3488|M.avium_104 FGGLLWWVVFGLHDEPLAAATLICLVTSQVISYIKARAEASGLRGDGGII
Mflv_3836|M.gilvum_PYR-GCK FCGLLWWAAFGLQSAELVVATMICLVSSQVISYIKARAEASGLSGDGGLI
Mvan_2560|M.vanbaalenii_PYR-1 FCGLLWWAAFGLHSTGLVVATMICLVSSQVISYIKARAEASGLSGDGGLI
MSMEG_2933|M.smegmatis_MC2_155 FAGLTWWAAFGLDSPSLVVATLICLVTSQVISYIKARAEASGLRGDGGII
MAB_2896c|M.abscessus_ATCC_199 FAGLVWWAAFGWGSTSLVVATLICMITSQVISYVKARAEASGLRADGGLI
TH_0577|M.thermoresistible__bu LIGLSLLGDLPWWVTAVILVREIGITALRFAVLRHGVIPAS--RG-GKLK
: ** : : . * : :. :. ** . . :
Mb2644c|M.bovis_AF2122/97 ERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVW
Rv2612c|M.tuberculosis_H37Rv ERPERLIIVLTGAGVSDFPFVPWPPALSVGMWLLAVASVITCVQRLHTVW
MMAR_2090|M.marinum_M ERPERLIIVLAGAGVSDFPFIAWPPALPVAMWLLAVTSVITCGQRLYTVW
MUL_3254|M.ulcerans_Agy99 ERPERLIIVLAGAGVSDFPFIAWPPALPVAMWLLAVTSVITCGQRLYTVW
MLBr_00454|M.leprae_Br4923 ERPERLIIVLVGAGLSDFPVYSLPWALSVAMWLLVVASLITCAQRLHTVH
MAV_3488|M.avium_104 ERPERLIIVLVGAGLSDLPGYPLPWALPVAMWALAAASLVTCAQRLHTVR
Mflv_3836|M.gilvum_PYR-GCK ERPERLVIVLVGAGLAGFPLFPLPWLLHVAMWLLAVTSLITVGQRLHSVR
Mvan_2560|M.vanbaalenii_PYR-1 ERPERLVIILVGACFSDLPFFPLPWLLDVAMWVLALSSVVTVGQRLHSVR
MSMEG_2933|M.smegmatis_MC2_155 ERPERLVIVLIGAGLSDLPFFPLPWTLHVAMWVLAVASVVTLLQRVHAVR
MAB_2896c|M.abscessus_ATCC_199 ERPERLIIVLAGAIFSGG--FGVQWPLHTAMWVLAVASLVTVAQRMHAVR
TH_0577|M.thermoresistible__bu TLAQAVAIGLFVLPLANWAPVWSTVAWGIMAVAVVLTVFTGVDYVVSAVR
.: : * * .:. :. : . : :*
Mb2644c|M.bovis_AF2122/97 TSPGAID-----------------RMAIP-----GKGDR
Rv2612c|M.tuberculosis_H37Rv TSPGAID-----------------RMAIP-----GKGDR
MMAR_2090|M.marinum_M TSPGATDLLVPSAPVRDDDAQGHPRSGDP-----GKTQR
MUL_3254|M.ulcerans_Agy99 TSPGATDLLVPSAPVRDDDAQGHPRSGDP-----GKTQR
MLBr_00454|M.leprae_Br4923 TSPGATDRIARPGYPSASDRTNATNGGQPGPGNLGTGEP
MAV_3488|M.avium_104 TSPGATDR--------------------------GSDAP
Mflv_3836|M.gilvum_PYR-GCK TSAAAMEPLSVPD--------------KP-----ETTEQ
Mvan_2560|M.vanbaalenii_PYR-1 TSAAAMEPLKVPEA-----------GEKP-----ETTEQ
MSMEG_2933|M.smegmatis_MC2_155 TSPGAMEPLHPAN------------GEKP-----ETSEP
MAB_2896c|M.abscessus_ATCC_199 TSPGALDLLPNSD-----------AGQDT----AETNQP
TH_0577|M.thermoresistible__bu DSRGRSAGH------------------------------
* .