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MRAGADAPDSGRVKESAPWSYDEAFCRNLGLISPTEQQRLRNSRVAIAGMGGVGGIDMVALARMGIGKFT IADPDVFEIRNSNRQYGAMRSTNGQAKAEVMRNIVHDINPEAEIRAFCEPIGKENAATFLEGADVLVDGI DAFEIDLRRLLYREAQQRGIYALGAGPLGFSTAWVVFDPKGMTFDRYFDLSDAMNTVDKFVAFIAGIAPS ATHRRSIDLSYVDIENRTGPSVGLACHLASGVVAAEVLKILLGHGRVYAAPYFHQFDAYRSIYVRKRLRC GNRHPLQRVKRRLLARYINRRSAGVIPGLRYHRTEPSY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2366c | moeW | - | 100% (318) | hypothetical protein Mb2366c |
| M. bovis AF2122 / 97 | Mb3231c | moeB1 | 2e-12 | 26.02% (246) | molybdopterin biosynthesis-like protein MoeZ |
| M. bovis AF2122 / 97 | Mb3143 | moeB2 | 3e-11 | 34.58% (107) | molybdenum cofactor biosynthesis protein MoeB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4670 | - | 4e-11 | 32.71% (107) | molybdopterin biosynthesis-like protein MoeZ |
| M. tuberculosis H37Rv | Rv2338c | moeW | 0.0 | 100.00% (318) | hypothetical protein Rv2338c |
| M. leprae Br4923 | MLBr_00817 | moeZ | 6e-11 | 31.11% (135) | molybdopterin biosynthesis-like protein MoeZ |
| M. abscessus ATCC 19977 | MAB_3525c | - | 1e-12 | 35.51% (107) | molybdenum cofactor biosynthesis protein MoeB1 |
| M. marinum M | MMAR_1352 | moeB1 | 2e-11 | 34.58% (107) | molybdenum cofactor biosynthesis protein MoeB1 |
| M. avium 104 | MAV_4153 | - | 2e-10 | 33.64% (107) | molybdopterin biosynthesis-like protein MoeZ |
| M. smegmatis MC2 155 | MSMEG_1937 | - | 1e-10 | 31.78% (107) | molybdopterin biosynthesis-like protein MoeZ |
| M. thermoresistible (build 8) | TH_0450 | moeZ | 2e-12 | 33.64% (107) | PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB1 |
| M. ulcerans Agy99 | MUL_2527 | moeB1 | 1e-11 | 34.58% (107) | molybdopterin biosynthesis-like protein MoeZ |
| M. vanbaalenii PYR-1 | Mvan_1797 | - | 4e-10 | 30.84% (107) | molybdopterin biosynthesis-like protein MoeZ |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1352|M.marinum_M ---MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQKRLKNARVL
MUL_2527|M.ulcerans_Agy99 ---MSTTALPPLVAPAATLSREEVARYSRHLIIPDLGVDGQKRLKNARVL
Mflv_4670|M.gilvum_PYR-GCK ----MSTPLPPLVEPAAELTKEEVARYSRHLIIPDLGLDGQKRLKNARVL
Mvan_1797|M.vanbaalenii_PYR-1 ----MSTPLPPLVEPAAELTREEVARYSRHLIIPDVGLDGQKRLKNARVL
MSMEG_1937|M.smegmatis_MC2_155 MSANLDVSLPPLVEPADELTREEVARYSRHLIIPDLGLDGQKRLKNAKVL
MAB_3525c|M.abscessus_ATCC_199 ----MPT-LPPLVRPAAELTREEVARYSRHLIIPDLGVDGQKRLKNAKVL
TH_0450|M.thermoresistible__bu ----VSSPLPPLVEPAAELTREEVARYSRHLIIPDVGVEGQKRLKNARVL
MLBr_00817|M.leprae_Br4923 -MSTSSTSLPPLVEPAGQLSRDEVIRYSRHLIIPDIGVDGQMRLKSARVL
MAV_4153|M.avium_104 ----MSTPLPPLVAPADQLTADEMARYSRQLIIPGLGVDGQKRLKNARVL
Mb2366c|M.bovis_AF2122/97 MRAGADAPDSGRVKESAPWSYDEAFCRNLGLISPTE----QQRLRNSRVA
Rv2338c|M.tuberculosis_H37Rv MRAGADAPDSGRVKESAPWSYDEAFCRNLGLISPTE----QQRLRNSRVA
. * : : :* . ** * * **:.::*
MMAR_1352|M.marinum_M VIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIHGVADVGRS
MUL_2527|M.ulcerans_Agy99 VIGAGGLGSPTLLYLAAAGVGTIGIVDFDVVDESNLQRQIIHGVADVGRS
Mflv_4670|M.gilvum_PYR-GCK VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRP
Mvan_1797|M.vanbaalenii_PYR-1 VIGAGGLGSPTLLYLAAAGVGTIGIVEFDLVDESNLQRQIIHGQSDIGRS
MSMEG_1937|M.smegmatis_MC2_155 VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRS
MAB_3525c|M.abscessus_ATCC_199 VIGAGGLGSPTLLYLAAAGVGTIGIVEFDVVDESNLQRQIIHGQSDIGRS
TH_0450|M.thermoresistible__bu VIGAGGLGSPALLYLAAAGVGTLGVIDFDVVDESNLQRQVIHGQADVGRP
MLBr_00817|M.leprae_Br4923 VIGAGGLGAPVLLYLAAAGVGTIGIIDFDVVDESNLQRQIIHGVADVGRS
MAV_4153|M.avium_104 VIGAGGLGAPTLLYLAAAGVGTIGIVEFDAVEESNLQRQIIHGVADVGRS
Mb2366c|M.bovis_AF2122/97 IAGMGGVGGIDMVALARMGIGKFTIADPDVFEIRNSNRQYGAMRSTNGQA
Rv2338c|M.tuberculosis_H37Rv IAGMGGVGGIDMVALARMGIGKFTIADPDVFEIRNSNRQYGAMRSTNGQA
: * **:*. :: ** *:*.: : : * .: * :** : *:.
MMAR_1352|M.marinum_M KAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGTDNFATR
MUL_2527|M.ulcerans_Agy99 KAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGTDNFATR
Mflv_4670|M.gilvum_PYR-GCK KAQSAKDSVLEVNPLVTVNLHEFRLEPDNAVELFEQYDLILDGTDNFATR
Mvan_1797|M.vanbaalenii_PYR-1 KAQSAKDSIAEINPLVNVVLHEFRLEPDNAVDLFAQYDLILDGTDNFATR
MSMEG_1937|M.smegmatis_MC2_155 KAQSARDSIAEINPLVTVNLHEFRLEPDNAVDLFGQYDLILDGTDNFATR
MAB_3525c|M.abscessus_ATCC_199 KAQSARDSVLEINPLVEVRLHELRLDPENAVELFAQYDLILDGTDNFATR
TH_0450|M.thermoresistible__bu KAESARDTIRAINPFVDVRLHQFRLDRSNAVDLFSEYDLILDGTDNFATR
MLBr_00817|M.leprae_Br4923 KAQSARDSIVAINPLVQVRLHEFRLESSNVVNLFKQYDLIVDGTDNFATR
MAV_4153|M.avium_104 KAASARDSIAAINPLVDVRLHEFRLDASNAVELFGHYDLIVDGTDNFATR
Mb2366c|M.bovis_AF2122/97 KAEVMRNIVHDINPEAEIRAFCEPIGKENAATFLEGADVLVDGIDAFEID
Rv2338c|M.tuberculosis_H37Rv KAEVMRNIVHDINPEAEIRAFCEPIGKENAATFLEGADVLVDGIDAFEID
** :: : :** : . : .*.. :: *:::** * *
MMAR_1352|M.marinum_M YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGLNYRDLY
MUL_2527|M.ulcerans_Agy99 YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGLNYRDLY
Mflv_4670|M.gilvum_PYR-GCK YLVNDAAVLAGKPYVWGSIYRFEGQVSIFWEDAP-----NGLGLNYRDLY
Mvan_1797|M.vanbaalenii_PYR-1 YLVNDAAVLAGKPYVWGSIYRFEGQISVFWEDAPADEAGNERGLNYRDLY
MSMEG_1937|M.smegmatis_MC2_155 YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----DGLGLNYRDLY
MAB_3525c|M.abscessus_ATCC_199 YLVNDAAVLAHKPYVWGSIYRFEGQVSVFWEDAP-----DGLGLNYRDLY
TH_0450|M.thermoresistible__bu YLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----NGQGLNYRDLY
MLBr_00817|M.leprae_Br4923 YLINDAAVLAKKPYVWGSLYRFEGQVSVFWEDAP-----DGLGLNYRDLY
MAV_4153|M.avium_104 YLINDAAVLAGKPYVWGSIYRFEGQASVCWEDAP-----DGRGLNYRDLY
Mb2366c|M.bovis_AF2122/97 LRR--------------LLYREAQQRGIYALGAG--------PLGFSTAW
Rv2338c|M.tuberculosis_H37Rv LRR--------------LLYREAQQRGIYALGAG--------PLGFSTAW
:** * .: .* *.: :
MMAR_1352|M.marinum_M PEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIGETLLGRLMI
MUL_2527|M.ulcerans_Agy99 PEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIGETLLGRLMI
Mflv_4670|M.gilvum_PYR-GCK PEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDPLLGRLMV
Mvan_1797|M.vanbaalenii_PYR-1 PEPPPPGMVPSCAEGGVLGILCASVGSVMGTEAIKLITGIGETLLGRLMV
MSMEG_1937|M.smegmatis_MC2_155 PEPPPPGMVPSCAEGGVLGILCSSIASIMGTEAIKLITGIGEPLLGRLMV
MAB_3525c|M.abscessus_ATCC_199 PEPPPPGMVPSCAEGGVLGILCASIASVMGTEAIKLITGIGDSLLGRLMV
TH_0450|M.thermoresistible__bu PEPPPPGMVPSCAEGGVLGILPATIGAIQGTEAIKLITGIGETLLGQLLI
MLBr_00817|M.leprae_Br4923 LEPPPPGMVPSCAEGGVLGIVCASIASVMGTEAIKLITGIGAPLLGRLMI
MAV_4153|M.avium_104 PEPPPPGAVPSCAEGGVLGVVCAAIASVMSTEVIKLITGIGESLLGRLMI
Mb2366c|M.bovis_AF2122/97 VVFDPKGMTFDRYFD-----LSDAMNTVD--KFVAFIAGIAPSATHR---
Rv2338c|M.tuberculosis_H37Rv VVFDPKGMTFDRYFD-----LSDAMNTVD--KFVAFIAGIAPSATHR---
* * . . . : :: :: : : :*:**. . :
MMAR_1352|M.marinum_M YDALEMTYRTIRIRKDP---ATPKITALIDYEQFCG---VVSDDVARAAS
MUL_2527|M.ulcerans_Agy99 YDALEMTYRTIRIRKDP---ATPKITALIDYEQFCG---VVSDDVARAAS
Mflv_4670|M.gilvum_PYR-GCK YDALDMSYRTIKIRKDP---STPKITELIDYEAFCG---VVSDAAAEAAA
Mvan_1797|M.vanbaalenii_PYR-1 YDALDMTYRTIKIRKDP---STPKITELIDYEAFCG---VVSDAAAEAAA
MSMEG_1937|M.smegmatis_MC2_155 YDALDMTYRTIRIRKDP---STPKITELIDYEEFCG---VVSDEAAAAAA
MAB_3525c|M.abscessus_ATCC_199 YDALDMTYRTIKIRKDP---ATPKITELIDYEAFCG---VISDEASAAVA
TH_0450|M.thermoresistible__bu YDALEMSYRKIRIRKDP---STPAITELIDYEEFCG---VVSDAAAEAAA
MLBr_00817|M.leprae_Br4923 YNALEMSYRRIRIHKDP---SRPKITELTDYQQFCG---VVSDDAAQVAT
MAV_4153|M.avium_104 YDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAASTDAATGGA
Mb2366c|M.bovis_AF2122/97 -RSIDLSYVDIENRTGP------------------------SVGLACHLA
Rv2338c|M.tuberculosis_H37Rv -RSIDLSYVDIENRTGP------------------------SVGLACHLA
:::::* * : .* * : :
MMAR_1352|M.marinum_M DSTITPQELRAMIDSGKKLALIDVREQVEWDIVHIDGAQLIPKSLISTGE
MUL_2527|M.ulcerans_Agy99 DSTITPQELRAMINSGKKLALIDVREQVEWDIVHIDGAQLIPKSLISTGE
Mflv_4670|M.gilvum_PYR-GCK DSTITPRELRELLDSGKPLALIDVREPVEWDINRIEGAELIPKGGFESGE
Mvan_1797|M.vanbaalenii_PYR-1 ESTITPRELRELMDSGKPLALIDVREPVEWDINHIEGAELIPKGAFESGE
MSMEG_1937|M.smegmatis_MC2_155 DSTVTPRELKELLDSGKPLALIDVRERVEWDINHIEGAELIPKPTFESGA
MAB_3525c|M.abscessus_ATCC_199 DSTITPRELRELLDTDKKVALIDVREPVEWDIVHIDGAELVPKSTLESGD
TH_0450|M.thermoresistible__bu DSTVTPRELRELLDAGK-VALVDVREPVEWEINRIEGAELIPKSEIESGV
MLBr_00817|M.leprae_Br4923 GSIVTPRELRELLDSGKKLALIDVREPVEWDIVHIDGAQLIPRSLINSGE
MAV_4153|M.avium_104 EAAITPRQLRELLDSGAKLALIDVREPVEFDIVHLDGAQLIPQSSINSGE
Mb2366c|M.bovis_AF2122/97 SGVVAAEVLKILLGHGRVYAAPYFHQFDAYRSIYVR-------KRLRCG-
Rv2338c|M.tuberculosis_H37Rv SGVVAAEVLKILLGHGRVYAAPYFHQFDAYRSIYVR-------KRLRCG-
. ::.. *: ::. . * .:: : : : *
MMAR_1352|M.marinum_M GLAKLPQDRTTVLYCKTGVRSAEALAALKKAGFADAVHLQGGIVAWANQM
MUL_2527|M.ulcerans_Agy99 GLAKLPQDRTTVLYCKTGVRSAEALAALKKAGFADAAHLQGGIVAWANQM
Mflv_4670|M.gilvum_PYR-GCK ALSKLDNDRTPVFYCKTGIRSAEVLAIVKKAGFADAMHVQGGIVAWGKQL
Mvan_1797|M.vanbaalenii_PYR-1 ALSKLKVDRTPVFYCKTGIRSAEVLAIVKKAGFSDAMHVQGGIVAWGKQL
MSMEG_1937|M.smegmatis_MC2_155 ALAKLPTDRTPVFYCKTGVRSAEVLAIAKKAGFSDAVHLQGGIVAWAKQL
MAB_3525c|M.abscessus_ATCC_199 GLAKLPQDRQAVLYCKTGIRSAEALVAVKKAGFSDAVHLQGGIAAWAKQV
TH_0450|M.thermoresistible__bu GLAKLPMDRAPVLYCKTGVRSAEALAAVKRAGFADAMHLQGGIVAWAKQL
MLBr_00817|M.leprae_Br4923 GLAKLPQDRMSVLYCKTGVRSAETLATVKKAGFSDAVHLQGGIVAWAKQV
MAV_4153|M.avium_104 GLAKLPADRMPVLYCKTGVRSAQALAVVRQAGFSDAVHLQGGIVAWAQQM
Mb2366c|M.bovis_AF2122/97 -------NRHPLQRVKR--RLLARYINRRSAGVIPGLRYHRTEPSY----
Rv2338c|M.tuberculosis_H37Rv -------NRHPLQRVKR--RLLARYINRRSAGVIPGLRYHRTEPSY----
:* .: * * : **. . : : ::
MMAR_1352|M.marinum_M QPDMVMY
MUL_2527|M.ulcerans_Agy99 QPDMVMY
Mflv_4670|M.gilvum_PYR-GCK EPDMVMY
Mvan_1797|M.vanbaalenii_PYR-1 EPDMVMY
MSMEG_1937|M.smegmatis_MC2_155 EPDMVMY
MAB_3525c|M.abscessus_ATCC_199 DPDMVMY
TH_0450|M.thermoresistible__bu EPDMVMY
MLBr_00817|M.leprae_Br4923 QPDMVIY
MAV_4153|M.avium_104 QPDMILY
Mb2366c|M.bovis_AF2122/97 -------
Rv2338c|M.tuberculosis_H37Rv -------