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MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFTRILTGVDIHP GAVIGARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGE DSRIGANAVVVKPVPPSAVVVGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQA AGVIRPPEAGIWHGEDFSI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2363 | cysE | - | 100% (229) | serine acetyltransferase CysE |
| M. bovis AF2122 / 97 | Mb1046c | glmU | 5e-06 | 29.75% (121) | UDP-N-acetylglucosamine pyrophosphorylase glmU |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2121 | - | 1e-06 | 36.28% (113) | carbonic anhydrase |
| M. tuberculosis H37Rv | Rv2335 | cysE | 1e-132 | 100.00% (229) | serine acetyltransferase CysE |
| M. leprae Br4923 | MLBr_00838 | cysE | 3e-97 | 76.42% (229) | putative serine acetyltransferase |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3646 | cysE | 1e-98 | 76.96% (230) | serine acetyltransferase CysE |
| M. avium 104 | MAV_2051 | cysE | 1e-102 | 78.17% (229) | serine O-acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_5947 | cysE | 1e-10 | 34.95% (103) | serine O-acetyltransferase |
| M. thermoresistible (build 8) | TH_1450 | cysE | 4e-53 | 58.33% (168) | PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) |
| M. ulcerans Agy99 | MUL_1464 | cysE | 8e-98 | 76.52% (230) | serine acetyltransferase CysE |
| M. vanbaalenii PYR-1 | Mvan_4782 | glmU | 5e-05 | 36.59% (82) | UDP-N-acetylglucosamine pyrophosphorylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2363|M.bovis_AF2122/97 --------------------------------------------------
Rv2335|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3646|M.marinum_M --------------------------------------------------
MUL_1464|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00838|M.leprae_Br4923 --------------------------------------------------
MAV_2051|M.avium_104 --------------------------------------------------
TH_1450|M.thermoresistible__bu --------------------------------------------------
MSMEG_5947|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2121|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4782|M.vanbaalenii_PYR-1 MRDAAVVILAAGAGTRMKSDTPKVLHTLAGRSMLSHALHAVAGLEARHLV
Mb2363|M.bovis_AF2122/97 --------------------------------------------------
Rv2335|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3646|M.marinum_M --------------------------------------------------
MUL_1464|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00838|M.leprae_Br4923 --------------------------------------------------
MAV_2051|M.avium_104 --------------------------------------------------
TH_1450|M.thermoresistible__bu --------------------------------------------------
MSMEG_5947|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2121|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4782|M.vanbaalenii_PYR-1 VVVGKDRERVAPAALEIGQTLGRDVDIAIQDQQRGTGHAVECGLTALPAD
Mb2363|M.bovis_AF2122/97 --------------------------------------------------
Rv2335|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3646|M.marinum_M --------------------------------------------------
MUL_1464|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00838|M.leprae_Br4923 --------------------------------------------------
MAV_2051|M.avium_104 --------------------------------------------------
TH_1450|M.thermoresistible__bu --------------------------------------------------
MSMEG_5947|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2121|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4782|M.vanbaalenii_PYR-1 FTGTVVVTAGDVPLLDTHTLSDLIAAHDAESAAATLLTTTLADPTGYGRI
Mb2363|M.bovis_AF2122/97 --------------------------------------------------
Rv2335|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3646|M.marinum_M --------------------------------------------------
MUL_1464|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00838|M.leprae_Br4923 --------------------------------------------------
MAV_2051|M.avium_104 --------------------------------------------------
TH_1450|M.thermoresistible__bu --------------------------------------------------
MSMEG_5947|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2121|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4782|M.vanbaalenii_PYR-1 LRTQDGGVIGIVEQADATPSQRAITEVNAAVYAFDAGALRSALSRLQADN
Mb2363|M.bovis_AF2122/97 ------------MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGH
Rv2335|M.tuberculosis_H37Rv ------------MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGH
MMAR_3646|M.marinum_M ----------MTMLTQIRRDIQAARQRDPARPTTLEVIFCYPGVHAVWGH
MUL_1464|M.ulcerans_Agy99 ------------MLTQIRRDIQAARQRDPARPTTLEVIFCYPGVHAVWGH
MLBr_00838|M.leprae_Br4923 ------------MFAAIRRDIQAARQRDPAQPTVLEVICCYPGVHAVWGH
MAV_2051|M.avium_104 ------------MLAAIRRDIRAARERDPAAPTTLQVIFAYPGVHAIWGH
TH_1450|M.thermoresistible__bu ----------MALFAVLREDLRNARAHDPAARGDLENALVYSGLHAIWAH
MSMEG_5947|M.smegmatis_MC2_155 -----------MVAEDVDWWMRCIDEPDLSALDHYSRFAYLSGALREFRT
Mflv_2121|M.gilvum_PYR-GCK ----------------MAEPLIVSLAGHTPDLHPDSWVAPNATVIGQVVL
Mvan_4782|M.vanbaalenii_PYR-1 AQGELYLTDVIAIARSDGGVVRARHIDDAALVAGVNDRVQLADLAAVLNR
: . . . .
Mb2363|M.bovis_AF2122/97 RLAHWLWQR--GARLLARAAAEF-------------TRILTGVDIHPGAV
Rv2335|M.tuberculosis_H37Rv RLAHWLWQR--GARLLARAAAEF-------------TRILTGVDIHPGAV
MMAR_3646|M.marinum_M RISHWLWRR--NARLVARALGEI-------------NRILTGVDIHPGAV
MUL_1464|M.ulcerans_Agy99 RISQWLWRR--NARLVARALGEI-------------NRILTGVDIHPGAV
MLBr_00838|M.leprae_Br4923 RISHWLWNR--RARLAARAFAEL-------------TRILTGVDIHPGAV
MAV_2051|M.avium_104 RVNHWLWRR--GARLAARICAEI-------------TRILTGVEIHPGAV
TH_1450|M.thermoresistible__bu RVAHRMWARP-ALRGPARVLMQI-------------VRAVTGIEIHPGAT
MSMEG_5947|M.smegmatis_MC2_155 LVHYRLQSAPWPLRMLLRKLYPP-------------EPTLT-LDVGS---
Mflv_2121|M.gilvum_PYR-GCK AAGASAWYG-----AILRAEVEV-------------IDIGAGTNIQD---
Mvan_4782|M.vanbaalenii_PYR-1 RIVEGHQRAGVTIIDPASTWIDVDVTIGRDTVVRPGTQLLGATTIGGRAE
:
Mb2363|M.bovis_AF2122/97 I-------------GARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSG
Rv2335|M.tuberculosis_H37Rv I-------------GARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSG
MMAR_3646|M.marinum_M L-------------GGGLFIDHATGVVIGETAEVGDDVTLYHGVTLGGTG
MUL_1464|M.ulcerans_Agy99 L-------------GGGLFIDHATGVVIGETAEVGDDVTLYHGVTLGGTG
MLBr_00838|M.leprae_Br4923 L-------------GAGLFIDHATGVVIGETAEVGDDVTIFHGVTLGGTG
MAV_2051|M.avium_104 L-------------GPGLFIDHATGVVIGETAEVGEDVTIYHGVTLGGSG
TH_1450|M.thermoresistible__bu I-------------GRRFFIDHGMGVVIGETAEIGDDVMIYHGVTLGGRT
MSMEG_5947|M.smegmatis_MC2_155 I-------------GPAFFIQHGVGTIV-AAESIGSHCWINQQVTIG---
Mflv_2121|M.gilvum_PYR-GCK --------------GVTIHVDPGFPVRIGAGVSVGHNAVLHG--------
Mvan_4782|M.vanbaalenii_PYR-1 IGPDTTLADVTVGDGAAVIRTHGTSAVIGDDSVVGPFTYLRPGTELGAAG
* . . . : :* :
Mb2363|M.bovis_AF2122/97 MV---------------------------------------------GGK
Rv2335|M.tuberculosis_H37Rv MV---------------------------------------------GGK
MMAR_3646|M.marinum_M TD---------------------------------------------VGK
MUL_1464|M.ulcerans_Agy99 TD---------------------------------------------VGK
MLBr_00838|M.leprae_Br4923 RE---------------------------------------------TGK
MAV_2051|M.avium_104 RD---------------------------------------------TGK
TH_1450|M.thermoresistible__bu LK---------------------------------------------KVK
MSMEG_5947|M.smegmatis_MC2_155 -H---------------------------------------------NTR
Mflv_2121|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4782|M.vanbaalenii_PYR-1 KLGAFVETKNATIGTGTKVPHLTYVGDADIGEHSNIGASSVFVNYDGETK
Mb2363|M.bovis_AF2122/97 RHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVK--PVPPSAVVVGV
Rv2335|M.tuberculosis_H37Rv RHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVK--PVPPSAVVVGV
MMAR_3646|M.marinum_M RHPTLGDRVIIGAGAKILGPIKIGDDSRVGANSVVVK--EVPSSAVVVGV
MUL_1464|M.ulcerans_Agy99 RHPTLGDRVIIGAGAKILGPIKIGDDSRVGANSVVVK--EVPSSAVVVGV
MLBr_00838|M.leprae_Br4923 RHPTIGDRVTIGAGAKVLGAIKIGEDSRIGANAVVVK--EVPASAVAVGV
MAV_2051|M.avium_104 RHPTIGDRVIIGAGAKVLGAIKIGDDSRIGANAVVVK--EVPSSAVVVGV
TH_1450|M.thermoresistible__bu RHPTIGNRVTIGAGAKVLGPITVGDDSAIGANAVVTR--DVPPESIATGI
MSMEG_5947|M.smegmatis_MC2_155 GRPTLGDHVRVGAGAVVIGPITLHDRATIGVNATVIH--DVPAGATVVAP
Mflv_2121|M.gilvum_PYR-GCK --CTVEENSLVGMGAVVLNGAVVGAGSLIAAGAVVPQGAVIPPGSMVAGV
Mvan_4782|M.vanbaalenii_PYR-1 SRTTIGSHVRTGSDTMFVAPVTVGDGAYTGAGTVVRE--DVPPGALAVSA
*: .. * .: .: : : ...:.* . :*. : ...
Mb2363|M.bovis_AF2122/97 PGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEAL-GGGPQAAG
Rv2335|M.tuberculosis_H37Rv PGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEAL-GGGPQAAG
MMAR_3646|M.marinum_M PGQVISR--QGPSGDDDSLLPDLVGVSLQSLLTRVARLEAQVDDRPPNAR
MUL_1464|M.ulcerans_Agy99 PGQVISR--QGPSGDDDSLLPDLVGVSLQSLLTRVARLEAQVDDRPPNAR
MLBr_00838|M.leprae_Br4923 PGQIISS--DSPANGDDSVLPDFVGVSLQSLLTRVAKLEAE-DGGSQTYR
MAV_2051|M.avium_104 PGQVIARTHPGPGGPDDSLMPDLVGVSLQSLLTRVTKLEAKVDGSQ-TGR
TH_1450|M.thermoresistible__bu PAVVRRR-------------------------TDREREEAV---------
MSMEG_5947|M.smegmatis_MC2_155 AATMLNR-------------------------PATGDAQA----------
Mflv_2121|M.gilvum_PYR-GCK PGKVRRQ-------------------------LGEDELAGIRTNATLYQE
Mvan_4782|M.vanbaalenii_PYR-1 GPQRNIEG------------------WVTRKRPGSAAAEAAAAAGAGAGA
.
Mb2363|M.bovis_AF2122/97 VIRPPEAGIWHGEDFSI
Rv2335|M.tuberculosis_H37Rv VIRPPEAGIWHGEDFSI
MMAR_3646|M.marinum_M VIRPPEAGVWHGEDFSI
MUL_1464|M.ulcerans_Agy99 VIRPPEAGVWHGEDFSI
MLBr_00838|M.leprae_Br4923 VIRLPEAGVWHGEDFSI
MAV_2051|M.avium_104 VIRPPEAGVWYGEDFSI
TH_1450|M.thermoresistible__bu -----DPTCYIDPAMYI
MSMEG_5947|M.smegmatis_MC2_155 -----------------
Mflv_2121|M.gilvum_PYR-GCK LVKAHRDAYNS------
Mvan_4782|M.vanbaalenii_PYR-1 AAEDQGPEATGE-----