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VVAEDVDWWMRCIDEPDLSALDHYSRFAYLSGALREFRTLVHYRLQSAPWPLRMLLRKLYPPEPTLTLDV GSIGPAFFIQHGVGTIVAAESIGSHCWINQQVTIGHNTRGRPTLGDHVRVGAGAVVIGPITLHDRATIGV NATVIHDVPAGATVVAPAATMLNRPATGDAQA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5947 | cysE | - | 100% (172) | serine O-acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_5426 | glmU | 3e-05 | 32.00% (75) | UDP-N-acetylglucosamine pyrophosphorylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2363 | cysE | 6e-11 | 34.95% (103) | serine acetyltransferase CysE |
| M. gilvum PYR-GCK | Mflv_1944 | glmU | 7e-07 | 34.67% (75) | UDP-N-acetylglucosamine pyrophosphorylase |
| M. tuberculosis H37Rv | Rv2335 | cysE | 6e-11 | 34.95% (103) | serine acetyltransferase CysE |
| M. leprae Br4923 | MLBr_00838 | cysE | 3e-12 | 35.58% (104) | putative serine acetyltransferase |
| M. abscessus ATCC 19977 | MAB_1148c | glmU | 7e-06 | 32.00% (75) | UDP-N-acetylglucosamine pyrophosphorylase (GlmU) |
| M. marinum M | MMAR_3646 | cysE | 1e-11 | 32.99% (97) | serine acetyltransferase CysE |
| M. avium 104 | MAV_2051 | cysE | 8e-13 | 36.63% (101) | serine O-acetyltransferase |
| M. thermoresistible (build 8) | TH_1450 | cysE | 1e-13 | 39.80% (98) | PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) |
| M. ulcerans Agy99 | MUL_1464 | cysE | 9e-12 | 32.99% (97) | serine acetyltransferase CysE |
| M. vanbaalenii PYR-1 | Mvan_4782 | glmU | 4e-07 | 36.00% (75) | UDP-N-acetylglucosamine pyrophosphorylase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3646|M.marinum_M --------------------------------------------------
MUL_1464|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00838|M.leprae_Br4923 --------------------------------------------------
MAV_2051|M.avium_104 --------------------------------------------------
Mb2363|M.bovis_AF2122/97 --------------------------------------------------
Rv2335|M.tuberculosis_H37Rv --------------------------------------------------
TH_1450|M.thermoresistible__bu --------------------------------------------------
Mflv_1944|M.gilvum_PYR-GCK ----MSDAAVVILAAGAGTRMKSDTPKVLHSLAGRSMLAHSMHAVAGLGP
Mvan_4782|M.vanbaalenii_PYR-1 ----MRDAAVVILAAGAGTRMKSDTPKVLHTLAGRSMLSHALHAVAGLEA
MAB_1148c|M.abscessus_ATCC_199 MPGNTAGTAVIVLAAGAGTRMCSDIPKVLHTLGGRSMLAHAVYAAASVNP
MSMEG_5947|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3646|M.marinum_M --------------------------------------------------
MUL_1464|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00838|M.leprae_Br4923 --------------------------------------------------
MAV_2051|M.avium_104 --------------------------------------------------
Mb2363|M.bovis_AF2122/97 --------------------------------------------------
Rv2335|M.tuberculosis_H37Rv --------------------------------------------------
TH_1450|M.thermoresistible__bu --------------------------------------------------
Mflv_1944|M.gilvum_PYR-GCK RHLVVVVGKHREQVAPAALQIGEHLGRTVDIAVQEEQRGTGHAVECGLAA
Mvan_4782|M.vanbaalenii_PYR-1 RHLVVVVGKDRERVAPAALEIGQTLGRDVDIAIQDQQRGTGHAVECGLTA
MAB_1148c|M.abscessus_ATCC_199 EHLVIVLGHERERIATAVDILAESLGRRIEIAVQEQQLGTGHAVACGLQA
MSMEG_5947|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3646|M.marinum_M --------------------------------------------------
MUL_1464|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00838|M.leprae_Br4923 --------------------------------------------------
MAV_2051|M.avium_104 --------------------------------------------------
Mb2363|M.bovis_AF2122/97 --------------------------------------------------
Rv2335|M.tuberculosis_H37Rv --------------------------------------------------
TH_1450|M.thermoresistible__bu --------------------------------------------------
Mflv_1944|M.gilvum_PYR-GCK LPADFHGVVVVTAGDVPLLDTDTLAQLIATHDAESADVTLLTTTMADPTG
Mvan_4782|M.vanbaalenii_PYR-1 LPADFTGTVVVTAGDVPLLDTHTLSDLIAAHDAESAAATLLTTTLADPTG
MAB_1148c|M.abscessus_ATCC_199 LPAGFAGTVVVTSGDIPLLDGGTLAGLIGSHTSEPAAATLLTTTLTDPTG
MSMEG_5947|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3646|M.marinum_M -MTMLTQIRRDIQAARQRDPARPTTLEVIFCYPGVHAVWGHRISHWLWRR
MUL_1464|M.ulcerans_Agy99 ---MLTQIRRDIQAARQRDPARPTTLEVIFCYPGVHAVWGHRISQWLWRR
MLBr_00838|M.leprae_Br4923 ---MFAAIRRDIQAARQRDPAQPTVLEVICCYPGVHAVWGHRISHWLWNR
MAV_2051|M.avium_104 ---MLAAIRRDIRAARERDPAAPTTLQVIFAYPGVHAIWGHRVNHWLWRR
Mb2363|M.bovis_AF2122/97 ---MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQR
Rv2335|M.tuberculosis_H37Rv ---MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQR
TH_1450|M.thermoresistible__bu -MALFAVLREDLRNARAHDPAARGDLENALVYSGLHAIWAHRVAHRMWAR
Mflv_1944|M.gilvum_PYR-GCK YGRILRTQDGEVIGIVEQADATESQRAITEVNAAVYAFGVGALRSALSRL
Mvan_4782|M.vanbaalenii_PYR-1 YGRILRTQDGGVIGIVEQADATPSQRAITEVNAAVYAFDAGALRSALSRL
MAB_1148c|M.abscessus_ATCC_199 YGRILRTQDREVIAIVEQTDATESQRAIGEVNAGVYAFDIEPLHAALSRL
MSMEG_5947|M.smegmatis_MC2_155 --MVAEDVDWWMRCIDEPDLSALDHYSRFAYLSGALREFRTLVHYRLQSA
: : : .. : :
MMAR_3646|M.marinum_M ------------------------------------------------NA
MUL_1464|M.ulcerans_Agy99 ------------------------------------------------NA
MLBr_00838|M.leprae_Br4923 ------------------------------------------------RA
MAV_2051|M.avium_104 ------------------------------------------------GA
Mb2363|M.bovis_AF2122/97 ------------------------------------------------GA
Rv2335|M.tuberculosis_H37Rv ------------------------------------------------GA
TH_1450|M.thermoresistible__bu P-----------------------------------------------AL
Mflv_1944|M.gilvum_PYR-GCK KTDNAQGELYLTDAIALVRGDGGTVRAVHVDDPALVAGVNDRVQLADLGA
Mvan_4782|M.vanbaalenii_PYR-1 QADNAQGELYLTDVIAIARSDGGVVRARHIDDAALVAGVNDRVQLADLAA
MAB_1148c|M.abscessus_ATCC_199 RSNNAQHELYLTDAVSIIRESGKVVHANHVDDSALVAGVNDRVQLSELGA
MSMEG_5947|M.smegmatis_MC2_155 P----------------------------------------------WPL
MMAR_3646|M.marinum_M RLVARALGEINR------------------------ILTGVDIHPGAVLG
MUL_1464|M.ulcerans_Agy99 RLVARALGEINR------------------------ILTGVDIHPGAVLG
MLBr_00838|M.leprae_Br4923 RLAARAFAELTR------------------------ILTGVDIHPGAVLG
MAV_2051|M.avium_104 RLAARICAEITR------------------------ILTGVEIHPGAVLG
Mb2363|M.bovis_AF2122/97 RLLARAAAEFTR------------------------ILTGVDIHPGAVIG
Rv2335|M.tuberculosis_H37Rv RLLARAAAEFTR------------------------ILTGVDIHPGAVIG
TH_1450|M.thermoresistible__bu RGPARVLMQIVR------------------------AVTGIEIHPGATIG
Mflv_1944|M.gilvum_PYR-GCK ELNRRVVAAHQRAGVTIVDPATTWIDVDVTIGRDTVVRPGTQLLGATAVG
Mvan_4782|M.vanbaalenii_PYR-1 VLNRRIVEGHQRAGVTIIDPASTWIDVDVTIGRDTVVRPGTQLLGATTIG
MAB_1148c|M.abscessus_ATCC_199 ELNRRIIRHHQRNGVTIIDPSSTWIDVDVHIGQDATIAPGTQLHSATVIG
MSMEG_5947|M.smegmatis_MC2_155 RMLLRKLYPPEP-------------------------TLTLDVGSIG---
* ::
MMAR_3646|M.marinum_M -------------------GGLFIDHATGVVIGETAEVGDDVTLYHGVTL
MUL_1464|M.ulcerans_Agy99 -------------------GGLFIDHATGVVIGETAEVGDDVTLYHGVTL
MLBr_00838|M.leprae_Br4923 -------------------AGLFIDHATGVVIGETAEVGDDVTIFHGVTL
MAV_2051|M.avium_104 -------------------PGLFIDHATGVVIGETAEVGEDVTIYHGVTL
Mb2363|M.bovis_AF2122/97 -------------------ARVFIDHATGVVIGETAEVGDDVTIYHGVTL
Rv2335|M.tuberculosis_H37Rv -------------------ARVFIDHATGVVIGETAEVGDDVTIYHGVTL
TH_1450|M.thermoresistible__bu -------------------RRFFIDHGMGVVIGETAEIGDDVMIYHGVTL
Mflv_1944|M.gilvum_PYR-GCK GRCEIGPDTTLTDVTVGDGAQVIRTHGTSSQIGAGAVVGPFTYLRPGTAL
Mvan_4782|M.vanbaalenii_PYR-1 GRAEIGPDTTLADVTVGDGAAVIRTHGTSAVIGDDSVVGPFTYLRPGTEL
MAB_1148c|M.abscessus_ATCC_199 GHCHIGPDTTLIDVTVGDSATVIRTHGQGSTIGARSVIGPFTYLRPGTVT
MSMEG_5947|M.smegmatis_MC2_155 -------------------PAFFIQHGVG-TIVAAESIGSHCWINQQVTI
.: *. . * :* : .
MMAR_3646|M.marinum_M GGTGTD---VGKRHPTLGDRVIIGAGAKILGPIKIGDDSRVGANSVVV--
MUL_1464|M.ulcerans_Agy99 GGTGTD---VGKRHPTLGDRVIIGAGAKILGPIKIGDDSRVGANSVVV--
MLBr_00838|M.leprae_Br4923 GGTGRE---TGKRHPTIGDRVTIGAGAKVLGAIKIGEDSRIGANAVVV--
MAV_2051|M.avium_104 GGSGRD---TGKRHPTIGDRVIIGAGAKVLGAIKIGDDSRIGANAVVV--
Mb2363|M.bovis_AF2122/97 GGSGMV---GGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVV--
Rv2335|M.tuberculosis_H37Rv GGSGMV---GGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVV--
TH_1450|M.thermoresistible__bu GGRTLK---KVKRHPTIGNRVTIGAGAKVLGPITVGDDSAIGANAVVT--
Mflv_1944|M.gilvum_PYR-GCK GADGKLGAFVETKNATIGTGTKVPH-LTYVGDADIGEHSNIGASSVFVNY
Mvan_4782|M.vanbaalenii_PYR-1 GAAGKLGAFVETKNATIGTGTKVPH-LTYVGDADIGEHSNIGASSVFVNY
MAB_1148c|M.abscessus_ATCC_199 GESAKLGAFVEVKNSTVGRGTKVPH-LTYVGDADIGEHSNIGASSVFVNY
MSMEG_5947|M.smegmatis_MC2_155 GHNTRG-------RPTLGDHVRVGAGAVVIGPITLHDRATIGVNATVI--
* ..*:* . : :* : : : :*..:..
MMAR_3646|M.marinum_M ------KEVPSSAVVVGVPGQVISR--QGPSGDDDSLLPDLVGVSLQSLL
MUL_1464|M.ulcerans_Agy99 ------KEVPSSAVVVGVPGQVISR--QGPSGDDDSLLPDLVGVSLQSLL
MLBr_00838|M.leprae_Br4923 ------KEVPASAVAVGVPGQIISS--DSPANGDDSVLPDFVGVSLQSLL
MAV_2051|M.avium_104 ------KEVPSSAVVVGVPGQVIARTHPGPGGPDDSLMPDLVGVSLQSLL
Mb2363|M.bovis_AF2122/97 ------KPVPPSAVVVGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLL
Rv2335|M.tuberculosis_H37Rv ------KPVPPSAVVVGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLL
TH_1450|M.thermoresistible__bu ------RDVPPESIATGIPAVVRRR-------------------------
Mflv_1944|M.gilvum_PYR-GCK DGETKSRTTIGSHVRTGSDTMFVAPVTVGDGAYTGAGTVIRDDVPPGALA
Mvan_4782|M.vanbaalenii_PYR-1 DGETKSRTTIGSHVRTGSDTMFVAPVTVGDGAYTGAGTVVREDVPPGALA
MAB_1148c|M.abscessus_ATCC_199 DGETKRRTVIGSHVKTGSDTMFVAPVTVGDGAYTGAGTVIREDVPPGALA
MSMEG_5947|M.smegmatis_MC2_155 ------HDVPAGATVVAPAATMLNR-------------------------
: . .. .
MMAR_3646|M.marinum_M TRVARLEAQVDDRPPNARVIRPPEAGVWHGEDFSI---------------
MUL_1464|M.ulcerans_Agy99 TRVARLEAQVDDRPPNARVIRPPEAGVWHGEDFSI---------------
MLBr_00838|M.leprae_Br4923 TRVAKLEAE-DGGSQTYRVIRLPEAGVWHGEDFSI---------------
MAV_2051|M.avium_104 TRVTKLEAKVDGSQ-TGRVIRPPEAGVWYGEDFSI---------------
Mb2363|M.bovis_AF2122/97 TRVARLEAL-GGGPQAAGVIRPPEAGIWHGEDFSI---------------
Rv2335|M.tuberculosis_H37Rv TRVARLEAL-GGGPQAAGVIRPPEAGIWHGEDFSI---------------
TH_1450|M.thermoresistible__bu TDREREEAV--------------DPTCYIDPAMYI---------------
Mflv_1944|M.gilvum_PYR-GCK VSAGPQRNIEGWVARKRPGSKAAAAAEAAAADGDTAAADRAAATAKPAPA
Mvan_4782|M.vanbaalenii_PYR-1 VSAGPQRNIEGWVTRKRPGSAAAEAAAAAGAGAGAAAEDQGPE------A
MAB_1148c|M.abscessus_ATCC_199 VSAGRQRNIEGWVAQKRPGSDAAKAAEEASKGS-----------------
MSMEG_5947|M.smegmatis_MC2_155 PATGDAQA------------------------------------------
.
MMAR_3646|M.marinum_M ---
MUL_1464|M.ulcerans_Agy99 ---
MLBr_00838|M.leprae_Br4923 ---
MAV_2051|M.avium_104 ---
Mb2363|M.bovis_AF2122/97 ---
Rv2335|M.tuberculosis_H37Rv ---
TH_1450|M.thermoresistible__bu ---
Mflv_1944|M.gilvum_PYR-GCK TGE
Mvan_4782|M.vanbaalenii_PYR-1 TGE
MAB_1148c|M.abscessus_ATCC_199 ---
MSMEG_5947|M.smegmatis_MC2_155 ---