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M. gilvum PYR-GCK Mflv_2121 (-)

annotation: carbonic anhydrase
coordinates: 2199642 - 2200169
length: 175

MAEPLIVSLAGHTPDLHPDSWVAPNATVIGQVVLAAGASAWYGAILRAEVEVIDIGAGTNIQDGVTIHVD
PGFPVRIGAGVSVGHNAVLHGCTVEENSLVGMGAVVLNGAVVGAGSLIAAGAVVPQGAVIPPGSMVAGVP
GKVRRQLGEDELAGIRTNATLYQELVKAHRDAYNS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_2121--100% (175)carbonic anhydrase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3555c-5e-3441.21% (165) siderophore-binding protein
M. tuberculosis H37RvRv3525c-5e-3441.21% (165) siderophore-binding protein
M. leprae Br4923MLBr_00838cysE7e-0528.57% (98) putative serine acetyltransferase
M. abscessus ATCC 19977MAB_4172c-6e-3446.76% (139) siderophore-binding protein
M. marinum MMMAR_5014-6e-3240.00% (165) hypothetical protein MMAR_5014
M. avium 104MAV_0634-5e-3440.61% (165) carnitine operon protein CaiE
M. smegmatis MC2 155MSMEG_5191-6e-6869.77% (172) siderophore binding protein
M. thermoresistible (build 8)TH_1984-2e-7172.67% (172) siderophore binding protein
M. ulcerans Agy99MUL_4088-8e-3240.00% (165) hypothetical protein MUL_4088
M. vanbaalenii PYR-1Mvan_1729-3e-0529.17% (120) nucleotidyl transferase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_5191|M.smegmatis_MC2_155      ----MPEPLIIPILGHAPQLDPESFVAPN---------------------
TH_1984|M.thermoresistible__bu      ----MPEPLIVALGDHAPQLHPESWVAPT---------------------
Mflv_2121|M.gilvum_PYR-GCK          ----MAEPLIVSLAGHTPDLHPDSWVAPN---------------------
MMAR_5014|M.marinum_M               ----MP---LFSFEGRSPRVDPTAFVAPT---------------------
MUL_4088|M.ulcerans_Agy99           ----MP---LFSFEGRSPRVDPTAFVAPT---------------------
Mb3555c|M.bovis_AF2122/97           ----MP---LFSFEGRSPRIDPTAFVAPT---------------------
Rv3525c|M.tuberculosis_H37Rv        ----MP---LFSFEGRSPRIDPTAFVAPT---------------------
MAV_0634|M.avium_104                ----MP---LFAFEGRSPRVDPTAFVAPT---------------------
MAB_4172c|M.abscessus_ATCC_199      ----MP---LYSLDGKSPSVHPEAFVAPT---------------------
Mvan_1729|M.vanbaalenii_PYR-1       MVNPAEVDAVVLVGGMGTRLRPLTLSAPKPMLPTAGLPFLTHLLSRIADA
MLBr_00838|M.leprae_Br4923          -----------MFAAIRRDIQAARQRDPAQ--------------------
                                                .      : .     *                      

MSMEG_5191|M.smegmatis_MC2_155      ------------------------------ASVIGQVSLAAR--------
TH_1984|M.thermoresistible__bu      ------------------------------ASVIGQVKLAAK--------
Mflv_2121|M.gilvum_PYR-GCK          ------------------------------ATVIGQVVLAAG--------
MMAR_5014|M.marinum_M               ------------------------------ATLIGDVTVEAG--------
MUL_4088|M.ulcerans_Agy99           ------------------------------ATLIGDVTVEAG--------
Mb3555c|M.bovis_AF2122/97           ------------------------------ATLIGDVTIEAG--------
Rv3525c|M.tuberculosis_H37Rv        ------------------------------ATLIGDVTIEAG--------
MAV_0634|M.avium_104                ------------------------------ATLIGDVVVEAG--------
MAB_4172c|M.abscessus_ATCC_199      ------------------------------ACLIGDVTVEAG--------
Mvan_1729|M.vanbaalenii_PYR-1       GIEHVVLGTSYKANVFESEFGDGSKLGLQIDYVVEDEPLGTGGGIANVAS
MLBr_00838|M.leprae_Br4923          ------------------------------PTVLEVICCYPG--------
                                                                    ::      .         

MSMEG_5191|M.smegmatis_MC2_155      ------ASVWYGATLR----------------------------------
TH_1984|M.thermoresistible__bu      ------VSVWYGATLR----------------------------------
Mflv_2121|M.gilvum_PYR-GCK          ------ASAWYGAILR----------------------------------
MMAR_5014|M.marinum_M               ------ASVWFNAVLR----------------------------------
MUL_4088|M.ulcerans_Agy99           ------ASVWFNAVFR----------------------------------
Mb3555c|M.bovis_AF2122/97           ------ASVWFNAVLR----------------------------------
Rv3525c|M.tuberculosis_H37Rv        ------ASVWFNAVLR----------------------------------
MAV_0634|M.avium_104                ------ASVWFNAVLR----------------------------------
MAB_4172c|M.abscessus_ATCC_199      ------VSIWFNTVIR----------------------------------
Mvan_1729|M.vanbaalenii_PYR-1       KLRYDTAVVFNGDVLSGCDLRALLDSHVSRDADVTLHLVRVGDPRAFGCV
MLBr_00838|M.leprae_Br4923          -----VHAVWGHRISHWLWN------------------------------
                                             :                                        

MSMEG_5191|M.smegmatis_MC2_155      ---------------AESEPIEIGEGSNIQDGVTVHVDP-----------
TH_1984|M.thermoresistible__bu      ---------------AEAEPIDIGEGTNIQDGTTIHVDP-----------
Mflv_2121|M.gilvum_PYR-GCK          ---------------AEVEVIDIGAGTNIQDGVTIHVDP-----------
MMAR_5014|M.marinum_M               ---------------GDYAPVVIREGANVQDGSVLHAPP-----------
MUL_4088|M.ulcerans_Agy99           ---------------GDYAPVVIREGANVQDGSVLHAPP-----------
Mb3555c|M.bovis_AF2122/97           ---------------GDYAPVVVREGANVQDGAVLHAPP-----------
Rv3525c|M.tuberculosis_H37Rv        ---------------GDYAPVVVREGANVQDGAVLHAPP-----------
MAV_0634|M.avium_104                ---------------GDYGPIVVREGANVQDGSVLHAPP-----------
MAB_4172c|M.abscessus_ATCC_199      ---------------ADYAPIIIRVGANIQDGSVLHSDP-----------
Mvan_1729|M.vanbaalenii_PYR-1       PTDSDGNVTAFLEKTQDPPTDQINAGCYVFKRSVIDAIPKGRALSVEREI
MLBr_00838|M.leprae_Br4923          -------RRARLAARAFAELTRILTGVDIHPGAVLGAGLFIDHATG----
                                                          :  *  :    .:               

MSMEG_5191|M.smegmatis_MC2_155      -----------------------GFPCRLGTG-----VTVGHNVVLHG--
TH_1984|M.thermoresistible__bu      -----------------------GFPVTVGAA-----VSVGHNAVLHG--
Mflv_2121|M.gilvum_PYR-GCK          -----------------------GFPVRIGAG-----VSVGHNAVLHG--
MMAR_5014|M.marinum_M               -----------------------GIPVDIGPG-----ATVAHLCVIHG--
MUL_4088|M.ulcerans_Agy99           -----------------------GIPVDIGPG-----ATVAHLCVIHG--
Mb3555c|M.bovis_AF2122/97           -----------------------GIPVDIGPG-----ATVAHLCVIHG--
Rv3525c|M.tuberculosis_H37Rv        -----------------------GIPVDIGPG-----ATVAHLCVIHG--
MAV_0634|M.avium_104                -----------------------GIPVDIGPG-----ATVAHLCVIHG--
MAB_4172c|M.abscessus_ATCC_199      -----------------------GMPVDIGEG-----ATVAHMCLVHS--
Mvan_1729|M.vanbaalenii_PYR-1       FPQLLSDGKRVCGYVDATYWRDMGTPEDFVRGSADLVRGIAPSPALHGH-
MLBr_00838|M.leprae_Br4923          --------------------VVIGETAEVGDD-----VTIFHGVTLGGTG
                                                           * .  .          :     : .  

MSMEG_5191|M.smegmatis_MC2_155      -------CTVEDDSLIGMGAVVLNGAVIGAGSLVAAGA-----VVPQGMV
TH_1984|M.thermoresistible__bu      -------CTVEEGALIGMGAIILNGAVVGAGSLVAAGA-----LVPQGFV
Mflv_2121|M.gilvum_PYR-GCK          -------CTVEENSLVGMGAVVLNGAVVGAGSLIAAGA-----VVPQGAV
MMAR_5014|M.marinum_M               -------VHVGAEALIANHATILDGAVIGARCLVAAHS-----LVVGGTQ
MUL_4088|M.ulcerans_Agy99           -------VHVGAEALIANHATVLDGAVIGARCLVAAHS-----LVVGGTQ
Mb3555c|M.bovis_AF2122/97           -------VHVGSEALIANHATVLDGAVIGARCMIAAGA-----LVVAGTQ
Rv3525c|M.tuberculosis_H37Rv        -------VHVGSEALIANHATVLDGAVIGARCMIAAGA-----LVVAGTQ
MAV_0634|M.avium_104                -------AHVGPEALIANHATVLDGAVIGAGSLVAAHS-----LVTAGTQ
MAB_4172c|M.abscessus_ATCC_199      -------CTVGDGALIGNHATVLDGASIGARSMVAAGS-----LVLGGAQ
Mvan_1729|M.vanbaalenii_PYR-1       ----RGESLVHDGASVAPGALLIGGTVVGRGAEVAGGARLDGAVIFDGVK
MLBr_00838|M.leprae_Br4923          RETGKRHPTIGDRVTIGAGAKVLGAIKIGEDSRIGANAVVVKEVPASAVA
                                             :     :.  * ::..  :*  . :.. :     :   .  

MSMEG_5191|M.smegmatis_MC2_155      VPP-RSLVA----------GVPGKVRREMS-DDEVEHNRFNAKAYVHLID
TH_1984|M.thermoresistible__bu      VPP-RSLVA----------GVPGKVRRELS-DDEVAANRFNSQVYQGLIE
Mflv_2121|M.gilvum_PYR-GCK          IPP-GSMVA----------GVPGKVRRQLG-EDELAGIRTNATLYQELVK
MMAR_5014|M.marinum_M               IPE-GMLVT----------GAPAKVKGPIAGTGAEMWVNVNPQAYRDLAA
MUL_4088|M.ulcerans_Agy99           IPE-GMLVT----------GAPAKVKGPIAGTGAEMWVNVNPQAYRDLAA
Mb3555c|M.bovis_AF2122/97           IPA-GMLVT----------GAPAKVKGPIEGTGAEMWVNVNPQAYRDLAA
Rv3525c|M.tuberculosis_H37Rv        IPA-GMLVT----------GAPAKVKGPIEGTGAEMWVNVNPQAYRDLAA
MAV_0634|M.avium_104                IPA-GMLAM----------GAPAQIKGPVAGTDAQLWVKLNPQAYRDLAQ
MAB_4172c|M.abscessus_ATCC_199      IPA-DVLVM----------GSPAKVKGPVAGTPAEFLTKGVPAAYRELGK
Mvan_1729|M.vanbaalenii_PYR-1       IGA-GAVIERSIIGFGARIGPRALIRDGVIGDGADIGARCELLRGARVWP
MLBr_00838|M.leprae_Br4923          VGVPGQIISSDSPANGDDSVLPDFVGVSLQSLLTRVAKLEAEDGGSQTYR
                                    :     :                 :   :                     

MSMEG_5191|M.smegmatis_MC2_155      LHRQAG-----------
TH_1984|M.thermoresistible__bu      PHRTANS----------
Mflv_2121|M.gilvum_PYR-GCK          AHRDAYNS---------
MMAR_5014|M.marinum_M               RHMAGLEPL--------
MUL_4088|M.ulcerans_Agy99           RHMAGLEPL--------
Mb3555c|M.bovis_AF2122/97           RHLAGLEPM--------
Rv3525c|M.tuberculosis_H37Rv        RHLAGLEPM--------
MAV_0634|M.avium_104                RHLAGLEPI--------
MAB_4172c|M.abscessus_ATCC_199      RYLAGLDK---------
Mvan_1729|M.vanbaalenii_PYR-1       GITIPDGGIRFSTDI--
MLBr_00838|M.leprae_Br4923          VIRLPEAGVWHGEDFSI