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MGSLAAFKLGWLLSAMAPNVVLLTAFRVPQGLTMLTVFATGQAGQHRCRTFHVTP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1733c | - | - | 100% (55) | hypothetical protein Mb1733c |
| M. bovis AF2122 / 97 | Mb0805c | emrB | 2e-05 | 64.52% (31) | multidrug resistance integral membrane efflux protein EmrB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv0783c | emrB | 2e-05 | 64.52% (31) | multidrug resistance integral membrane efflux protein EmrB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3100 | ermB_1 | 3e-05 | 43.40% (53) | integral membrane drug efflux protein, ErmB_1 |
| M. avium 104 | MAV_0729 | - | 2e-05 | 47.17% (53) | EmrB efflux protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0501 | - | 9e-05 | 59.38% (32) | integral membrane drug efflux protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0783c|M.tuberculosis_H37Rv MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVL
MUL_0501|M.ulcerans_Agy99 MLSTAMDEAHCTPAEVAPPDTRTGTSSPGEHVYPDRLDAGLLRIAGVCVL
MAV_0729|M.avium_104 MLSGAMEKTR--SAAFSVPLATASGPSLRDDEYPDKLDAALFRIAGVCGL
MMAR_3100|M.marinum_M -----MEPCG------ADARATATQLSPTQDNYPDRLDWPTIRIAGVCLI
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv ASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGW
MUL_0501|M.ulcerans_Agy99 ASLMSVLDATVVGIAQRTFIIEFDSTQAVVAWTMTGYTLALATVIPVAGW
MAV_0729|M.avium_104 ACIMAVLDSTVVAVAQRTFIAQFGANQAIVSWTIAGYMLAFATVIPITGW
MMAR_3100|M.marinum_M AAIMANLDISIVTVAQRTFTVAFHSTQATVAWTVAGYMLGMATATPMTGW
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv AADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTP
MUL_0501|M.ulcerans_Agy99 AADRFGTKRLWMGSVLAFALGSLLCALAPNILSLIFFRVLQGVGGGMLMP
MAV_0729|M.avium_104 AADRFGTKRLFMGSVLIFTLGSLLCAVAPNILLLILFRVVQGVGGGMLLP
MMAR_3100|M.marinum_M AADRLGAKRLFMGAVATFTLGSMLCASAPNIGLLITFRVVQGIGGGVLGP
Mb1733c|M.bovis_AF2122/97 -----------MGSLAAFKLGWLLSAMAPNVVLLTAFRVPQGLT--MLT-
**:: * ** :*.* ***: * *** **. :*
Rv0783c|M.tuberculosis_H37Rv VSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIF
MUL_0501|M.ulcerans_Agy99 LGFIILTRAAGPKRLGRLMAAIGIPMLLGPIGGPILGGWLISSFGWHWIF
MAV_0729|M.avium_104 LSFVILTREAGPKRVGRLMAVGGIPILLGPIGGPILGGWLIGAYGWKWIF
MMAR_3100|M.marinum_M LVLAIVTHQAGPRRLGRLLAVGAIPMLTAPMLGPILGGWLIDSYGWQWIF
Mb1733c|M.bovis_AF2122/97 ---VFATGQAGQHRCR--------TFHVTP--------------------
: : ** :* .: *
Rv0783c|M.tuberculosis_H37Rv LVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSS
MUL_0501|M.ulcerans_Agy99 LVNLPIGLAAFALAAITFPADRPVPSESFDVIGVLLLSPGLAAFLLALSL
MAV_0729|M.avium_104 LINLPIGLTAFALAALLFPKDRSAPSEALDITGALLLSPGVAIFLCGVCS
MMAR_3100|M.marinum_M LINVPAGLLAFGLAAILVPEDPPKPSERFDFIGMLLLLPGIAMLLLGVSA
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv SPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVA
MUL_0501|M.ulcerans_Agy99 IPDRGTVADRYVLIPVIAGLSLIGGFAWHAWHRADHPLIDLHLFNNSVVT
MAV_0729|M.avium_104 IPGRHTVADRYVLVPALVGLVLIAAFILHAWYRTEHPLIDLRLFRNPVVT
MMAR_3100|M.marinum_M IPGSGTVTDHRVWVPAISGAVLITAFALHAWYRTDHPLIDLRLFTDRVVR
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv QANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAM
MUL_0501|M.ulcerans_Agy99 QANLTLLAFAAAYFGSSLLIPTYLQQVLHQTPMQSGLYLIPQGLGAMLTM
MAV_0729|M.avium_104 QVNVTLLVFAAASVGVGLLVPSYFQIVGHETPMQSGLHMLPIGVGAVLTM
MMAR_3100|M.marinum_M LANLALLLYVAGAAGASLLLPSYFQQLLHQTPMRSGLMMVPIGFGAMLTM
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv PIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAI
MUL_0501|M.ulcerans_Agy99 PIASAFMDRRGPGKSVLLGIVLIAVGLAMFTFGVATRAQYLPTLLVGLAI
MAV_0729|M.avium_104 PLGGAVMDKHGPGKIVLTGLPLMAVGLAVFTYGVARQAAYSPVLVCGLAI
MMAR_3100|M.marinum_M PLTGAFMDSRGPRKVVLIGLTLIAAGTGTFVFGVANEADYLPTLLAGLTI
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv MGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVL
MUL_0501|M.ulcerans_Agy99 MGMGTGCTMMPLAGAAVLTLKPREIARGSTLISVTQQVGGSIGTALMATI
MAV_0729|M.avium_104 MGLGIGLTTTPLSAALMQALAPHQVARGTTLISVNQQVGGSIGAALMAVI
MMAR_3100|M.marinum_M AGMGLGCTGLLLAASVMRVLAPHQIARGSALISVNQQISGSIGAALMSMI
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv LTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTN---FAAQLL
MUL_0501|M.ulcerans_Agy99 LTNQFNRSDNIWVANKVATLEQNAAARGVTVDPSGLPPQALTPDFADNVM
MAV_0729|M.avium_104 LTNQFNRNPALMAANEAAGMHPVTGKRGLPVDPSTVPRPAMTPELAGHVS
MMAR_3100|M.marinum_M LTNQFCRSHTISTANNMAVLRENAERHVVPIAPSAVPARAVGPDFLVELQ
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv HDLSHAYAVVFVIATALVVSTLIPAAFLPKQQAS-------HRRAPLLSA
MUL_0501|M.ulcerans_Agy99 HDLSHAYTVVFGVVVVLVVSTLIPAASLPKTPAAAPASFEQHHCDTQYGV
MAV_0729|M.avium_104 HHLSHAYTAVFVLAVVLVACTIIPASFLPRKPPS-----------PPAGD
MMAR_3100|M.marinum_M HDLSHAYTLTFAVAAVLGALAYFPAAFLPAKPTT--------IAPGEVDV
Mb1733c|M.bovis_AF2122/97 --------------------------------------------------
Rv0783c|M.tuberculosis_H37Rv ---
MUL_0501|M.ulcerans_Agy99 HRV
MAV_0729|M.avium_104 ---
MMAR_3100|M.marinum_M PG-
Mb1733c|M.bovis_AF2122/97 ---