For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSVMNGREVARESRDAQVFEFGTAPGSAVVKIPVQGGPIGGIAISRDGSLLVVTNNGTDTVSVVGTDTCR VTQTVTSVNEPFAIAMGNAEANRAYVSTVSSAYDAIAVIDVATNTVLGTHPLALSVSDLTLSPDDKYLYV SRNGTRGADVAVLDTTTGALIDVVDVSQAPGTTTQCVRMSPDGSVLYVGANGPSGGLLVVITTRAQSDGG RIGSRSRSRQKSSKPRGNQAAAGLRVVATIDIGSSVRDVALSPDGAIAYVASCGSDFGAVVDVIDTRTHQ ITSSRAISEIGGLVTRVSVSGDADRAYLVSEDRVTVLCTRTHDVIGTIRTGQPSCVVESPDGKYLYIADY SGTITRTAVASTIVSGTEQLALQRRGSMQWFSPELQQYAPALA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1086 | - | - | 100% (393) | hypothetical protein Mb1086 |
| M. bovis AF2122 / 97 | Mb1006c | PE_PGRS18 | 5e-08 | 29.33% (150) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2024 | - | 4e-41 | 32.13% (333) | hypothetical protein Mflv_2024 |
| M. tuberculosis H37Rv | Rv1057 | - | 0.0 | 100.00% (393) | hypothetical protein Rv1057 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4401 | - | 5e-08 | 23.08% (299) | putative surface layer protein |
| M. marinum M | MMAR_4413 | - | 1e-123 | 58.46% (402) | hypothetical protein MMAR_4413 |
| M. avium 104 | MAV_1185 | - | 2e-97 | 52.03% (369) | hypothetical protein MAV_1185 |
| M. smegmatis MC2 155 | MSMEG_5308 | - | 4e-46 | 34.23% (333) | hypothetical protein MSMEG_5308 |
| M. thermoresistible (build 8) | TH_4450 | - | 1e-38 | 33.13% (326) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0230 | - | 1e-124 | 58.96% (402) | hypothetical protein MUL_0230 |
| M. vanbaalenii PYR-1 | Mvan_4699 | - | 4e-42 | 30.92% (359) | hypothetical protein Mvan_4699 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1086|M.bovis_AF2122/97 ----------MSVMNGREVARESRD---AQVFEFG-----TAPG-SAVVK
Rv1057|M.tuberculosis_H37Rv ----------MSVMNGREVARESRD---AQVFEFG-----TAPG-SAVVK
MMAR_4413|M.marinum_M ----------MSDVNGQQTGWNDRDGGDVQVFELG-----TAPDFPTSVE
MUL_0230|M.ulcerans_Agy99 ----------MSDVNGQQTGWNDRDGGDVQVFELG-----TAPDFPTSVE
MAV_1185|M.avium_104 MNPGANSPRPYRRLRHLATRADKHSKGGTSVSDANGPTARFGIDNTAVVK
Mflv_2024|M.gilvum_PYR-GCK -------------MHNVHNRSSAEDTVR--------------GDIVRERV
Mvan_4699|M.vanbaalenii_PYR-1 --MANFSVPKGRLMLNGGAGSKAASHVADEPLTEA-----ATSDVVLERR
MSMEG_5308|M.smegmatis_MC2_155 MTMAKNILRAITAIVRRDAKTPDTDDSAGSVTFDG-----ALDDLDVAGL
TH_4450|M.thermoresistible__bu --VPAEVPDHMANIHLPAFQQNATVPRSGQLPAD-------QQEFTVTGA
MAB_4401|M.abscessus_ATCC_1997 -------------MTSPSAREGRAG--------------------DTLAV
:
Mb1086|M.bovis_AF2122/97 IPVQGGPIGGIAISRDGSLLVVTNNGTDTVSVVGTDTCRVTQTVTSVNEP
Rv1057|M.tuberculosis_H37Rv IPVQGGPIGGIAISRDGSLLVVTNNGTDTVSVVGTDTCRVTQTVTSVNEP
MMAR_4413|M.marinum_M IAVANGPIGDIGISPDGRRLMVTNYGDNSVSVIDTDTCRVVETITGIDEA
MUL_0230|M.ulcerans_Agy99 IAVANGPIGDIGISPDGSRLMVTNYGDNSVSVIDTDTCRVVETITGLDEA
MAV_1185|M.avium_104 VPVHHGPISDIDVSPDGRRLLVTNYGRDTVSVIDTHTCRVASTIAGLSEP
Mflv_2024|M.gilvum_PYR-GCK VRVQRGPIGDMATTDG--VVAIANPGDDSVSLLDPSTLTVVDTVVVDGEP
Mvan_4699|M.vanbaalenii_PYR-1 ITLGRGPVGDIAAGQG--FVVMANAGDDSVSVIDPMTLAVVDTIAVDGQP
MSMEG_5308|M.smegmatis_MC2_155 VEVGRGPIADIAIDADRETIVVTNSAADCLTVINPYTLAPVGSVRLNGEP
TH_4450|M.thermoresistible__bu VAVD-GPVADLAINADGHALVAAHCGRDAVSLLDPARLNVQAAVPLGGDP
MAB_4401|M.abscessus_ATCC_1997 VSQTGPTVSFFDAASDEMLGAIDVLAEPHELCFDPTQRLLWCTNTYHTGY
: .:. : . . ... :
Mb1086|M.bovis_AF2122/97 FAIAMGNAEANRAYVS-TVSSAYDAIAVIDVATNTVLGTHPLALSVSDLT
Rv1057|M.tuberculosis_H37Rv FAIAMGNAEANRAYVS-TVSSAYDAIAVIDVATNTVLGTHPLALSVSDLT
MMAR_4413|M.marinum_M FAVTTGGPAANRAYVS-TVSTAYDAIAVIDVATNAVVSTHPLALSVSDLA
MUL_0230|M.ulcerans_Agy99 FAVTAGGPAANRAYVS-TVSTAYDAIAVIDVATNAVVSTHPLALSVSDLA
MAV_1185|M.avium_104 FAVAMSAADPNYAYVS-TATAAYDAIEVIDVVTNWRIATHRLAHSLSDLA
Mflv_2024|M.gilvum_PYR-GCK QAVAVA---DGRAYVG-IAAAGHDAVAVVDLDSRTLIKTYPLAFGVTALA
Mvan_4699|M.vanbaalenii_PYR-1 VAVTAS---DDRAYVC-VAAESHDAVCAIDLEAGTVVSTHPLASGVTALA
MSMEG_5308|M.smegmatis_MC2_155 FAVAAA---DDRAYVS-VVTAGHDAIKVVDTITGSVLAEYPLAMTVTALA
TH_4450|M.thermoresistible__bu FHVAVT---RDHAYVSTISLRNEDAVEVVELGSGTVVATHPQRATITALV
MAB_4401|M.abscessus_ATCC_1997 YHANAG----RRTQLTVIDPDTRRVVDVVDLAPEHAPHGLALDTGRGLLY
: : .: .:: . *
Mb1086|M.bovis_AF2122/97 LSPDDKYLYVSRNGTRGADVAVLDTTTGALIDVVDVSQAPGTTTQCVRMS
Rv1057|M.tuberculosis_H37Rv LSPDDKYLYVSRNGTRGADVAVLDTTTGALIDVVDVSQAPGTTTQCVRMS
MMAR_4413|M.marinum_M ASSDGKYVYASRNGARGADIAVLDTATG-RVDVVDIATKPGLTTECVRVS
MUL_0230|M.ulcerans_Agy99 ASSDGKYVYASRNGARGADIAVLDTATG-RVDVVDIATKPGLTTECVRVS
MAV_1185|M.avium_104 VSPDGRYLYASRNAVRGADVAVLDTTTG-ELEVIELAAAAGTTTACVRVS
Mflv_2024|M.gilvum_PYR-GCK VSPDGKRVYAGRCVRDRVDVAVIDVTAE-RVGTIDIGRGPAANIDAMSVD
Mvan_4699|M.vanbaalenii_PYR-1 VSPDGKRVYAGRDAQDRVDVAVIDVTAE-RVGTIGIGSGPAANVDALSVD
MSMEG_5308|M.smegmatis_MC2_155 MSPDGKRVFVGRSGHDRIDVAVIDTAAE-RVGTIDLASGAGAGVDALRVD
TH_4450|M.thermoresistible__bu ASPDGKRVFVGRTDSERVDIAVIDTITG-EVDTVDAGWGPAINIDALHVV
MAB_4401|M.abscessus_ATCC_1997 VSVEG-------SNERDGGVVVIDTTTRKMLGRIDTG---APGPHWFVID
* :. .:.*:*. : : : . . . :
Mb1086|M.bovis_AF2122/97 PDGSVLYVGANGPSGGLLVVITTRAQSD-----GGRIGSRSRSRQKSSKP
Rv1057|M.tuberculosis_H37Rv PDGSVLYVGANGPSGGLLVVITTRAQSD-----GGRIGSRSRSRQKSSKP
MMAR_4413|M.marinum_M ADGQRVYVGANGPSGGQLIVVATHAESELNPVRGGRARSRGRNGKGVAGS
MUL_0230|M.ulcerans_Agy99 ADGNRVDVGANGPSGGQLIVVATHAESELNPVRGGRARSRGRNGQGVAGS
MAV_1185|M.avium_104 ADGRRLFVGVNGPNGGGLAIIETRTRTD-----GRRVGGRSR--------
Mflv_2024|M.gilvum_PYR-GCK PGGKRMYLAVTDTEGSRLIVVDTETSRVSR--------------------
Mvan_4699|M.vanbaalenii_PYR-1 PSGKRLYVAVTDAVGSRLVIVDTETSLVHR--------------------
MSMEG_5308|M.smegmatis_MC2_155 ASGKRLYVATTDPRGSRMVTVNIETAQIES--------------------
TH_4450|M.thermoresistible__bu DNGRRLHAAVSDACSSYLVNINVETARVEG--------------------
MAB_4401|M.abscessus_ATCC_1997 PTGEKGYASNKEAPFVSFVDLGSGTLTTVEVP------------------
* . . . : : :
Mb1086|M.bovis_AF2122/97 RGNQAAAGLRVVATIDIGSSVRDVALSPDGAIAYVASCGSDFGAVVDVID
Rv1057|M.tuberculosis_H37Rv RGNQAAAGLRVVATIDIGSSVRDVALSPDGAIAYVASCGSDFGAVVDVID
MMAR_4413|M.marinum_M VVKQFPRDLRIIDTIEIGSSVRDVAISPDGTTAYVASCGADFGAVIDVVD
MUL_0230|M.ulcerans_Agy99 VVQQFPRDLRIIDTIEIGSSVRDVAISPDGTTAYVASCGADFGAVIDVVD
MAV_1185|M.avium_104 ----------LVGTVELGLPVRDVALGNDGNTAYVASCGPVVGSVLDVVD
Mflv_2024|M.gilvum_PYR-GCK -------------VVPIGSPIRDLGY--AAGALYALTSDRAVGGAIHVVD
Mvan_4699|M.vanbaalenii_PYR-1 -------------VLPIGAPIRDIAY--AGGAVYVLTSDRAVGGTVHVVD
MSMEG_5308|M.smegmatis_MC2_155 -------------TVWIGAPIRDLALG-ADGKALVLTSDRQRRGVVHIVD
TH_4450|M.thermoresistible__bu -------------AVGIGAPIRDVAVG-PDLIAYVLTSDRHRGGSVAKVD
MAB_4401|M.abscessus_ATCC_1997 ----------GSEGLAISADGSELYVAAPYGSFKVGETDPTQQAGIRVID
: :. :: . . . : :*
Mb1086|M.bovis_AF2122/97 TRTHQITSSRAISEIGGLVTRVSVSGDADRAYLVSEDR-----------V
Rv1057|M.tuberculosis_H37Rv TRTHQITSSRAISEIGGLVTRVSVSGDADRAYLVSEDR-----------V
MMAR_4413|M.marinum_M TRTRKITGTRKIEEIGGLITRLSIGGNGERAYLVSEDR-----------V
MUL_0230|M.ulcerans_Agy99 TRTHKITGTRKIEEIGGLITRLSIGGNGERAYLVSEDR-----------V
MAV_1185|M.avium_104 TRAATIVSTHKINEITGPLTRMTLSRDGERAYLISDDR-----------V
Mflv_2024|M.gilvum_PYR-GCK LATWKVTEA---TTLGGAPTQLVMSADQTRAYVVDYDR-----------V
Mvan_4699|M.vanbaalenii_PYR-1 LNAMRVTDR---VVVGGAPTQLTMSADQTRAYIVDYDR-----------V
MSMEG_5308|M.smegmatis_MC2_155 LSTAAVVGA---IQIGGAPTQLVLSPDATRAYVVDYDR-----------V
TH_4450|M.thermoresistible__bu LAHGRIVER---VDIGGAPTQLVLAADGSRAYIVDYDS-----------V
MAB_4401|M.abscessus_ATCC_1997 TRQAQVTAVLKTENVVFPVCLTSTGTLLAGELRMSPDPSCTLGRHEPGLL
:. : . :. * :
Mb1086|M.bovis_AF2122/97 TVLCTRTHDVIGTIRTG--QPSCVVESPDGKYLYIADYSGTITRTAVAST
Rv1057|M.tuberculosis_H37Rv TVLCTRTHDVIGTIRTG--QPSCVVESPDGKYLYIADYSGTITRTAVAST
MMAR_4413|M.marinum_M TVLSARSQDVIGTVRVN--QPSAAIESPGGDRLYVADYSGTVTMTLVDLG
MUL_0230|M.ulcerans_Agy99 TVLSARSQDVIGTVRVN--QPSAAIESPGGDRLYVADYSGTVTMTLVDLG
MAV_1185|M.avium_104 TVLGTRTQDVLGEVRVTK-HPSALVESPDGNYLYVADHAGVLSVARLPSG
Mflv_2024|M.gilvum_PYR-GCK AVVSTSSLEVSDSLTAEA-RPSCVTQSADGTRLYIADYSGGVSVLSVESS
Mvan_4699|M.vanbaalenii_PYR-1 AVLCTLGLDVVDSLAVDA-RPSCVTHPADSSRLYIADYTGAVSVFSVESS
MSMEG_5308|M.smegmatis_MC2_155 IVLCTLTNEILGSIDVGM-QPAAVAVRRDGARVYVADYSGQVNAFDVAAE
TH_4450|M.thermoresistible__bu AVLCTVTNQVVHAIDPGA-APSGVALSPDGGRLFIADHTGRITMFAVAGA
MAB_4401|M.abscessus_ATCC_1997 RAFSTTTRELVASVELKGKFPLTMTASPDGRLGYVAGIT-SSEVDIVDLE
.. : :: : * .. ::*. : :
Mb1086|M.bovis_AF2122/97 IVSGTEQL-ALQRRGSMQWFSPELQQYAPALA
Rv1057|M.tuberculosis_H37Rv IVSGTEQL-ALQRRGSMQWFSPELQQYAPALA
MMAR_4413|M.marinum_M -VSAIDN--ALCQGLSADWVMPELLQFEAALA
MUL_0230|M.ulcerans_Agy99 -VSAIDN--ALCQGLSADWVMPELLQFEAALA
MAV_1185|M.avium_104 TAPAAPCSGADEDDDATTGWLPELAPWEPVLA
Mflv_2024|M.gilvum_PYR-GCK IEALYPHFLATDP--IAQTATRALQPAGV---
Mvan_4699|M.vanbaalenii_PYR-1 IETLYSQFLATDS--IALGVSRALQPTPA---
MSMEG_5308|M.smegmatis_MC2_155 LPALYSRLVASEPRQDATTVLPSLQTA-----
TH_4450|M.thermoresistible__bu QPLWPEAFLDTDP--IPAHRIPAEVA------
MAB_4401|M.abscessus_ATCC_1997 TWTVLNTLDIAKRGEAGAHGLAYIPRST----