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TMAKNILRAITAIVRRDAKTPDTDDSAGSVTFDGALDDLDVAGLVEVGRGPIADIAIDADRETIVVTNSA ADCLTVINPYTLAPVGSVRLNGEPFAVAAADDRAYVSVVTAGHDAIKVVDTITGSVLAEYPLAMTVTALA MSPDGKRVFVGRSGHDRIDVAVIDTAAERVGTIDLASGAGAGVDALRVDASGKRLYVATTDPRGSRMVTV NIETAQIESTVWIGAPIRDLALGADGKALVLTSDRQRRGVVHIVDLSTAAVVGAIQIGGAPTQLVLSPDA TRAYVVDYDRVIVLCTLTNEILGSIDVGMQPAAVAVRRDGARVYVADYSGQVNAFDVAAELPALYSRLVA SEPRQDATTVLPSLQTA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_5308 | - | - | 100% (368) | hypothetical protein MSMEG_5308 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1086 | - | 3e-46 | 34.23% (333) | hypothetical protein Mb1086 |
M. gilvum PYR-GCK | Mflv_2024 | - | 3e-81 | 49.53% (319) | hypothetical protein Mflv_2024 |
M. tuberculosis H37Rv | Rv1057 | - | 3e-46 | 34.23% (333) | hypothetical protein Rv1057 |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_4413 | - | 1e-44 | 33.63% (339) | hypothetical protein MMAR_4413 |
M. avium 104 | MAV_1185 | - | 3e-47 | 36.71% (316) | hypothetical protein MAV_1185 |
M. thermoresistible (build 8) | TH_4450 | - | 9e-76 | 45.74% (317) | PUTATIVE putative conserved hypothetical protein |
M. ulcerans Agy99 | MUL_0230 | - | 7e-44 | 33.63% (339) | hypothetical protein MUL_0230 |
M. vanbaalenii PYR-1 | Mvan_4699 | - | 3e-85 | 50.31% (320) | hypothetical protein Mvan_4699 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_2024|M.gilvum_PYR-GCK -------------MHNVHNRSSAEDTVR--------------GDIVRERV Mvan_4699|M.vanbaalenii_PYR-1 --MANFSVPKGRLMLNGGAGSKAASHVADEPLTEA-----ATSDVVLERR MSMEG_5308|M.smegmatis_MC2_155 MTMAKNILRAITAIVRRDAKTPDTDDSAGSVTFDG-----ALDDLDVAGL TH_4450|M.thermoresistible__bu --VPAEVPDHMANIHLPAFQQNATVPRSGQLPAD-------QQEFTVTGA Mb1086|M.bovis_AF2122/97 ----------MSVMNGREVARESRD---AQVFEFG-----TAPG-SAVVK Rv1057|M.tuberculosis_H37Rv ----------MSVMNGREVARESRD---AQVFEFG-----TAPG-SAVVK MMAR_4413|M.marinum_M ----------MSDVNGQQTGWNDRDGGDVQVFELG-----TAPDFPTSVE MUL_0230|M.ulcerans_Agy99 ----------MSDVNGQQTGWNDRDGGDVQVFELG-----TAPDFPTSVE MAV_1185|M.avium_104 MNPGANSPRPYRRLRHLATRADKHSKGGTSVSDANGPTARFGIDNTAVVK : Mflv_2024|M.gilvum_PYR-GCK VRVQRGPIGDMATTDG--VVAIANPGDDSVSLLDPSTLTVVDTVVVDGEP Mvan_4699|M.vanbaalenii_PYR-1 ITLGRGPVGDIAAGQG--FVVMANAGDDSVSVIDPMTLAVVDTIAVDGQP MSMEG_5308|M.smegmatis_MC2_155 VEVGRGPIADIAIDADRETIVVTNSAADCLTVINPYTLAPVGSVRLNGEP TH_4450|M.thermoresistible__bu VAVD-GPVADLAINADGHALVAAHCGRDAVSLLDPARLNVQAAVPLGGDP Mb1086|M.bovis_AF2122/97 IPVQGGPIGGIAISRDGSLLVVTNNGTDTVSVVGTDTCRVTQTVTSVNEP Rv1057|M.tuberculosis_H37Rv IPVQGGPIGGIAISRDGSLLVVTNNGTDTVSVVGTDTCRVTQTVTSVNEP MMAR_4413|M.marinum_M IAVANGPIGDIGISPDGRRLMVTNYGDNSVSVIDTDTCRVVETITGIDEA MUL_0230|M.ulcerans_Agy99 IAVANGPIGDIGISPDGSRLMVTNYGDNSVSVIDTDTCRVVETITGLDEA MAV_1185|M.avium_104 VPVHHGPISDIDVSPDGRRLLVTNYGRDTVSVIDTHTCRVASTIAGLSEP : : **:..: . : :: . : ::::.. :: .:. Mflv_2024|M.gilvum_PYR-GCK QAVAVA---DGRAYVG-IAAAGHDAVAVVDLDSRTLIKTYPLAFGVTALA Mvan_4699|M.vanbaalenii_PYR-1 VAVTAS---DDRAYVC-VAAESHDAVCAIDLEAGTVVSTHPLASGVTALA MSMEG_5308|M.smegmatis_MC2_155 FAVAAA---DDRAYVS-VVTAGHDAIKVVDTITGSVLAEYPLAMTVTALA TH_4450|M.thermoresistible__bu FHVAVT---RDHAYVSTISLRNEDAVEVVELGSGTVVATHPQRATITALV Mb1086|M.bovis_AF2122/97 FAIAMGNAEANRAYVS-TVSSAYDAIAVIDVATNTVLGTHPLALSVSDLT Rv1057|M.tuberculosis_H37Rv FAIAMGNAEANRAYVS-TVSSAYDAIAVIDVATNTVLGTHPLALSVSDLT MMAR_4413|M.marinum_M FAVTTGGPAANRAYVS-TVSTAYDAIAVIDVATNAVVSTHPLALSVSDLA MUL_0230|M.ulcerans_Agy99 FAVTAGGPAANRAYVS-TVSTAYDAIAVIDVATNAVVSTHPLALSVSDLA MAV_1185|M.avium_104 FAVAMSAADPNYAYVS-TATAAYDAIEVIDVVTNWRIATHRLAHSLSDLA :: . *** **: .:: : : : :: *. Mflv_2024|M.gilvum_PYR-GCK VSPDGKRVYAGRCVRDRVDVAVIDVTAE-RVGTIDIGRGPAANIDAMSVD Mvan_4699|M.vanbaalenii_PYR-1 VSPDGKRVYAGRDAQDRVDVAVIDVTAE-RVGTIGIGSGPAANVDALSVD MSMEG_5308|M.smegmatis_MC2_155 MSPDGKRVFVGRSGHDRIDVAVIDTAAE-RVGTIDLASGAGAGVDALRVD TH_4450|M.thermoresistible__bu ASPDGKRVFVGRTDSERVDIAVIDTITG-EVDTVDAGWGPAINIDALHVV Mb1086|M.bovis_AF2122/97 LSPDDKYLYVSRNGTRGADVAVLDTTTGALIDVVDVSQAPGTTTQCVRMS Rv1057|M.tuberculosis_H37Rv LSPDDKYLYVSRNGTRGADVAVLDTTTGALIDVVDVSQAPGTTTQCVRMS MMAR_4413|M.marinum_M ASSDGKYVYASRNGARGADIAVLDTATG-RVDVVDIATKPGLTTECVRVS MUL_0230|M.ulcerans_Agy99 ASSDGKYVYASRNGARGADIAVLDTATG-RVDVVDIATKPGLTTECVRVS MAV_1185|M.avium_104 VSPDGRYLYASRNAVRGADVAVLDTTTG-ELEVIELAAAAGTTTACVRVS *.*.: ::..* *:**:*. : : .: . .. .: : Mflv_2024|M.gilvum_PYR-GCK PGGKRMYLAVTDTEGSRLIVVDTETSRVSR-------------------- Mvan_4699|M.vanbaalenii_PYR-1 PSGKRLYVAVTDAVGSRLVIVDTETSLVHR-------------------- MSMEG_5308|M.smegmatis_MC2_155 ASGKRLYVATTDPRGSRMVTVNIETAQIES-------------------- TH_4450|M.thermoresistible__bu DNGRRLHAAVSDACSSYLVNINVETARVEG-------------------- Mb1086|M.bovis_AF2122/97 PDGSVLYVGANGPSGGLLVVITTRAQSD-----GGRIGSRSRSRQKSSKP Rv1057|M.tuberculosis_H37Rv PDGSVLYVGANGPSGGLLVVITTRAQSD-----GGRIGSRSRSRQKSSKP MMAR_4413|M.marinum_M ADGQRVYVGANGPSGGQLIVVATHAESELNPVRGGRARSRGRNGKGVAGS MUL_0230|M.ulcerans_Agy99 ADGNRVDVGANGPSGGQLIVVATHAESELNPVRGGRARSRGRNGQGVAGS MAV_1185|M.avium_104 ADGRRLFVGVNGPNGGGLAIIETRTRTD-----GRRVGGRSR-------- .* : ..... .. : : .: Mflv_2024|M.gilvum_PYR-GCK -------------VVPIGSPIRDLGY--AAGALYALTSDRAVGGAIHVVD Mvan_4699|M.vanbaalenii_PYR-1 -------------VLPIGAPIRDIAY--AGGAVYVLTSDRAVGGTVHVVD MSMEG_5308|M.smegmatis_MC2_155 -------------TVWIGAPIRDLALG-ADGKALVLTSDRQRRGVVHIVD TH_4450|M.thermoresistible__bu -------------AVGIGAPIRDVAVG-PDLIAYVLTSDRHRGGSVAKVD Mb1086|M.bovis_AF2122/97 RGNQAAAGLRVVATIDIGSSVRDVALSPDGAIAYVASCGSDFGAVVDVID Rv1057|M.tuberculosis_H37Rv RGNQAAAGLRVVATIDIGSSVRDVALSPDGAIAYVASCGSDFGAVVDVID MMAR_4413|M.marinum_M VVKQFPRDLRIIDTIEIGSSVRDVAISPDGTTAYVASCGADFGAVIDVVD MUL_0230|M.ulcerans_Agy99 VVQQFPRDLRIIDTIEIGSSVRDVAISPDGTTAYVASCGADFGAVIDVVD MAV_1185|M.avium_104 ----------LVGTVELGLPVRDVALGNDGNTAYVASCGPVVGSVLDVVD .: :* .:**:. . :.. . : :* Mflv_2024|M.gilvum_PYR-GCK LATWKVTEA---TTLGGAPTQLVMSADQTRAYVVDYDRVAVVSTSSLEVS Mvan_4699|M.vanbaalenii_PYR-1 LNAMRVTDR---VVVGGAPTQLTMSADQTRAYIVDYDRVAVLCTLGLDVV MSMEG_5308|M.smegmatis_MC2_155 LSTAAVVGA---IQIGGAPTQLVLSPDATRAYVVDYDRVIVLCTLTNEIL TH_4450|M.thermoresistible__bu LAHGRIVER---VDIGGAPTQLVLAADGSRAYIVDYDSVAVLCTVTNQVV Mb1086|M.bovis_AF2122/97 TRTHQITSSRAISEIGGLVTRVSVSGDADRAYLVSEDRVTVLCTRTHDVI Rv1057|M.tuberculosis_H37Rv TRTHQITSSRAISEIGGLVTRVSVSGDADRAYLVSEDRVTVLCTRTHDVI MMAR_4413|M.marinum_M TRTRKITGTRKIEEIGGLITRLSIGGNGERAYLVSEDRVTVLSARSQDVI MUL_0230|M.ulcerans_Agy99 TRTHKITGTRKIEEIGGLITRLSIGGNGERAYLVSEDRVTVLSARSQDVI MAV_1185|M.avium_104 TRAATIVSTHKINEITGPLTRMTLSRDGERAYLISDDRVTVLGTRTQDVL :. : * *:: :. : ***::. * * *: : :: Mflv_2024|M.gilvum_PYR-GCK DSLTAEARPSCVTQSADGTRLYIADYSGGVSVLSVESSIEALYPHFLATD Mvan_4699|M.vanbaalenii_PYR-1 DSLAVDARPSCVTHPADSSRLYIADYTGAVSVFSVESSIETLYSQFLATD MSMEG_5308|M.smegmatis_MC2_155 GSIDVGMQPAAVAVRRDGARVYVADYSGQVNAFDVAAELPALYSRLVASE TH_4450|M.thermoresistible__bu HAIDPGAAPSGVALSPDGGRLFIADHTGRITMFAVAGAQPLWPEAFLDTD Mb1086|M.bovis_AF2122/97 GTIRTG-QPSCVVESPDGKYLYIADYSGTITRTAVASTIVSGTEQL-ALQ Rv1057|M.tuberculosis_H37Rv GTIRTG-QPSCVVESPDGKYLYIADYSGTITRTAVASTIVSGTEQL-ALQ MMAR_4413|M.marinum_M GTVRVN-QPSAAIESPGGDRLYVADYSGTVTMTLVDLG-VSAIDN--ALC MUL_0230|M.ulcerans_Agy99 GTVRVN-QPSAAIESPGGDRLYVADYSGTVTMTLVDLG-VSAIDN--ALC MAV_1185|M.avium_104 GEVRVTKHPSALVESPDGNYLYVADHAGVLSVARLPSGTAPAAPCSGADE : *: .. :::**::* :. : Mflv_2024|M.gilvum_PYR-GCK P--IAQTATRALQPAGV--- Mvan_4699|M.vanbaalenii_PYR-1 S--IALGVSRALQPTPA--- MSMEG_5308|M.smegmatis_MC2_155 PRQDATTVLPSLQTA----- TH_4450|M.thermoresistible__bu P--IPAHRIPAEVA------ Mb1086|M.bovis_AF2122/97 RRGSMQWFSPELQQYAPALA Rv1057|M.tuberculosis_H37Rv RRGSMQWFSPELQQYAPALA MMAR_4413|M.marinum_M QGLSADWVMPELLQFEAALA MUL_0230|M.ulcerans_Agy99 QGLSADWVMPELLQFEAALA MAV_1185|M.avium_104 DDDATTGWLPELAPWEPVLA