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M. bovis AF2122 / 97 Mb0235c (php)

annotation: phosphotriesterase
coordinates: 273307 - 274287
length: 326

VPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEDKRVAGAIARLGELKARGVDTIVDLTV
IGLGRYIPRIARVAAATELNIVVATGLYTYNDVPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIK
AGILKCATDEPGLTPGVERVLRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGVELSRVVIGHCGD
STDVGYLEELIAAGSYLGMDRFGVDVISPFQDRVNIVARMCERGHADKMVLSHDACCYFDALPEELVPVA
MPNWHYLHIHNDVIPALKQHGVTDEQLHTMLVDNPRRIFERQGGYQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0235cphp-100% (326)phosphotriesterase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0230cphp0.099.69% (326) phosphotriesterase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0487php1e-17288.34% (326) phosphotriesterase PHP
M. avium 104MAV_4940-1e-16692.46% (305) phosphotriesterase-like protein
M. smegmatis MC2 155MSMEG_0320-1e-15378.77% (325) putative phosphotriesterase
M. thermoresistible (build 8)TH_1316-1e-15178.88% (322) PROBABLE PHOSPHOTRIESTERASE PHP (PARATHION HYDROLASE) (PTE)
M. ulcerans Agy99MUL_1150php1e-17288.65% (326) phosphotriesterase PHP
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb0235c|M.bovis_AF2122/97           --MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEDKRVA
Rv0230c|M.tuberculosis_H37Rv        --MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEDKRVA
MAV_4940|M.avium_104                ----------------------MHEHVFIMTTEIAQNYPEAWGDEEQRVA
MMAR_0487|M.marinum_M               --MSALNTARGPIDTADLGVTLMHEHVFIMTTEVAQNYPEAWGDEEKRVA
MUL_1150|M.ulcerans_Agy99           --MSALNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEEKRVA
MSMEG_0320|M.smegmatis_MC2_155      --MPTVNTAAGAIDTADLGVTLMHEHVFIMTTEVMLNHPESWGDEHRREA
TH_1316|M.thermoresistible__bu      MGRRTVNTAGGSIDTADLGVTLMHEHVFVLTTEIAVNYPERWGDGARREA
                                                          ******::***:  *:** ***  :* *

Mb0235c|M.bovis_AF2122/97           GAIARLGELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLY
Rv0230c|M.tuberculosis_H37Rv        GAIARLGELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLY
MAV_4940|M.avium_104                DAIDRLNELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLY
MMAR_0487|M.marinum_M               DAITRLNELKSRGVDTIVDLTVIGLGRYIPRIARIAAATDLNIVVATGLY
MUL_1150|M.ulcerans_Agy99           DAITRLNELKSRGVDTIVDLTVIGLGRYIPRIARIAAATDLNIVVATGLY
MSMEG_0320|M.smegmatis_MC2_155      DAIVRLGELKARGVDTIVDLTVIGLGRYIPRIARIAEATELNIVVATGLY
TH_1316|M.thermoresistible__bu      DAVARLDELKSRGVDTIVDLTVIGLGRDLPRIVRIAEQTDLNIVVATGLY
                                    .*: **.***:**************** :***.*:*  *:**********

Mb0235c|M.bovis_AF2122/97           TYNDVPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIKAGILKCAT
Rv0230c|M.tuberculosis_H37Rv        TYNDVPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIKAGILKCAT
MAV_4940|M.avium_104                TYNDVPFYFHYLGPGAELGGPEIMTDMFVRDIEQGIADTGIKAGILKCAT
MMAR_0487|M.marinum_M               TYNDVPYRFHYQGPGGMLDGPEIMTDMFVRDIEQGIADTGVKAGILKCAT
MUL_1150|M.ulcerans_Agy99           TYNDVPYRFHYQGPGGMLDGPEIMTDMFVRDIEQGIADTGVKAGILKCAT
MSMEG_0320|M.smegmatis_MC2_155      TYNDIPMTFHFRGPGTALDGDEPMAEMFVRDIEKGIADTGIKAAILKCAT
TH_1316|M.thermoresistible__bu      TYNDVPFCFSLQGPGTELDGPESMTDMFVRDIEHGIADTGVKAAVLKCAT
                                    ****:*  *   ***  *.* * *::*******:******:**.:*****

Mb0235c|M.bovis_AF2122/97           DEPGLTPGVERVLRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGV
Rv0230c|M.tuberculosis_H37Rv        DEPGLTPGVERVLRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGV
MAV_4940|M.avium_104                DAPGVTPGVERVLRAVAQAHKRTGVPISTHTHAGLRRGLDQQRIFEEEGV
MMAR_0487|M.marinum_M               DEPGITPGVERVLRAVAQTHKRTGVPISTHTHAGLRRGLEQQRIFEEEGV
MUL_1150|M.ulcerans_Agy99           DEPGITPGVERVLRAVAQTHKRTGVPISTHTHAGLRRGLEQQRIFEEEGV
MSMEG_0320|M.smegmatis_MC2_155      DEPGVTPGVERVLRAVAAAHRQTGVPISTHTHAATRRGLEQQRVFAEEGV
TH_1316|M.thermoresistible__bu      DKPGVTAGVDRVLRAVAQAHRRTGVPISTHTHAASRRGLDQQRVFAEEGV
                                    * **:*.**:******* :*::**.********. ****:***:* ****

Mb0235c|M.bovis_AF2122/97           ELSRVVIGHCGDSTDVGYLEELIAAGSYLGMDRFGVDVISPFQDRVNIVA
Rv0230c|M.tuberculosis_H37Rv        DLSRVVIGHCGDSTDVGYLEELIAAGSYLGMDRFGVDVISPFQDRVNIVA
MAV_4940|M.avium_104                DLSRVVIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDAISPFEDRVNIVA
MMAR_0487|M.marinum_M               DLSRVIIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDLILPFEDRVSIVA
MUL_1150|M.ulcerans_Agy99           DLSRVIIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDLILPFEDRVNIVA
MSMEG_0320|M.smegmatis_MC2_155      DLTRVIIGHCGDTTDIGYLEELIANGSYIGMDRFGVDVFLPFEQRVATVA
TH_1316|M.thermoresistible__bu      DLSRVVIGHCGDTTDIGYLEQLIANGSYIGMDRFGVDTFLSFEDRVNTVA
                                    :*:**:***.**:**:****:*** ***:******:* : .*::**  **

Mb0235c|M.bovis_AF2122/97           RMCERGHADKMVLSHDACCYFDALPEELVPVAMPNWHYLHIHNDVIPALK
Rv0230c|M.tuberculosis_H37Rv        RMCERGHADKMVLSHDACCYFDALPEELVPVAMPNWHYLHIHNDVIPALK
MAV_4940|M.avium_104                QMCERGHADKMVLSHDANCYFDALPEELVPQVMPNWHYLHIHNDVIPALK
MMAR_0487|M.marinum_M               TMCERGHADKMVLSHDANCYFDALPEELTAVATPNWHYLHIHNDVIPALK
MUL_1150|M.ulcerans_Agy99           TMCERGHADKMVLSHDANCYFDALPEELTAVATPNWHYLHIHNDVIPALK
MSMEG_0320|M.smegmatis_MC2_155      TMCERGHAERMVLSHDTWCYFDALPDELTTAALPNSHYLHIHNDVIPALR
TH_1316|M.thermoresistible__bu      KMCELGYADRMVLSHDAHCYFDWLPEQLVAAGLPNWHYLHIHDDVIPALK
                                     *** *:*::******: **** **::*..   ** ******:******:

Mb0235c|M.bovis_AF2122/97           QHGVTDEQLHTMLVDNPRRIFERQGGYQ
Rv0230c|M.tuberculosis_H37Rv        QHGVTDEQLHTMLVDNPRRIFERQGGYQ
MAV_4940|M.avium_104                QRGVTDEQLHTMLVDNPRRIFERQGPYG
MMAR_0487|M.marinum_M               ERGVTDEQVHTMLVDNPRRIFERQGGYQ
MUL_1150|M.ulcerans_Agy99           ERGVTHEQVHTMLVDNPRRIFERQGGYQ
MSMEG_0320|M.smegmatis_MC2_155      QRGVTDEQITTMLVDNPRRIFEHKGGY-
TH_1316|M.thermoresistible__bu      QRGVTDEQLTTMLVDNPRRIFETQGGY-
                                    ::***.**: ************ :* *