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M. ulcerans Agy99 MUL_1150 (php)

annotation: phosphotriesterase PHP
coordinates: 1228670 - 1229650
length: 326

SALNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEEKRVADAITRLNELKSRGVDTIVDLTVI
GLGRYIPRIARIAAATDLNIVVATGLYTYNDVPYRFHYQGPGGMLDGPEIMTDMFVRDIEQGIADTGVKA
GILKCATDEPGITPGVERVLRAVAQTHKRTGVPISTHTHAGLRRGLEQQRIFEEEGVDLSRVIIGHSGDS
TDVGYLEELIAAGSYLGMDRFGIDLILPFEDRVNIVATMCERGHADKMVLSHDANCYFDALPEELTAVAT
PNWHYLHIHNDVIPALKERGVTHEQVHTMLVDNPRRIFERQGGYQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1150php-100% (326)phosphotriesterase PHP

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0235cphp1e-17288.65% (326) phosphotriesterase
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0230cphp1e-17288.96% (326) phosphotriesterase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0487php0.099.08% (326) phosphotriesterase PHP
M. avium 104MAV_4940-1e-16390.49% (305) phosphotriesterase-like protein
M. smegmatis MC2 155MSMEG_0320-1e-15279.19% (322) putative phosphotriesterase
M. thermoresistible (build 8)TH_1316-1e-15078.57% (322) PROBABLE PHOSPHOTRIESTERASE PHP (PARATHION HYDROLASE) (PTE)
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1150|M.ulcerans_Agy99           --MSALNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEEKRVA
MMAR_0487|M.marinum_M               --MSALNTARGPIDTADLGVTLMHEHVFIMTTEVAQNYPEAWGDEEKRVA
Mb0235c|M.bovis_AF2122/97           --MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEDKRVA
Rv0230c|M.tuberculosis_H37Rv        --MPELNTARGPIDTADLGVTLMHEHVFIMTTEIAQNYPEAWGDEDKRVA
MAV_4940|M.avium_104                ----------------------MHEHVFIMTTEIAQNYPEAWGDEEQRVA
MSMEG_0320|M.smegmatis_MC2_155      --MPTVNTAAGAIDTADLGVTLMHEHVFIMTTEVMLNHPESWGDEHRREA
TH_1316|M.thermoresistible__bu      MGRRTVNTAGGSIDTADLGVTLMHEHVFVLTTEIAVNYPERWGDGARREA
                                                          ******::***:  *:** ***  :* *

MUL_1150|M.ulcerans_Agy99           DAITRLNELKSRGVDTIVDLTVIGLGRYIPRIARIAAATDLNIVVATGLY
MMAR_0487|M.marinum_M               DAITRLNELKSRGVDTIVDLTVIGLGRYIPRIARIAAATDLNIVVATGLY
Mb0235c|M.bovis_AF2122/97           GAIARLGELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLY
Rv0230c|M.tuberculosis_H37Rv        GAIARLGELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLY
MAV_4940|M.avium_104                DAIDRLNELKARGVDTIVDLTVIGLGRYIPRIARVAAATELNIVVATGLY
MSMEG_0320|M.smegmatis_MC2_155      DAIVRLGELKARGVDTIVDLTVIGLGRYIPRIARIAEATELNIVVATGLY
TH_1316|M.thermoresistible__bu      DAVARLDELKSRGVDTIVDLTVIGLGRDLPRIVRIAEQTDLNIVVATGLY
                                    .*: **.***:**************** :***.*:*  *:**********

MUL_1150|M.ulcerans_Agy99           TYNDVPYRFHYQGPGGMLDGPEIMTDMFVRDIEQGIADTGVKAGILKCAT
MMAR_0487|M.marinum_M               TYNDVPYRFHYQGPGGMLDGPEIMTDMFVRDIEQGIADTGVKAGILKCAT
Mb0235c|M.bovis_AF2122/97           TYNDVPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIKAGILKCAT
Rv0230c|M.tuberculosis_H37Rv        TYNDVPFYFHYLGPGAQLDGPEIMTDMFVRDIEHGIADTGIKAGILKCAT
MAV_4940|M.avium_104                TYNDVPFYFHYLGPGAELGGPEIMTDMFVRDIEQGIADTGIKAGILKCAT
MSMEG_0320|M.smegmatis_MC2_155      TYNDIPMTFHFRGPGTALDGDEPMAEMFVRDIEKGIADTGIKAAILKCAT
TH_1316|M.thermoresistible__bu      TYNDVPFCFSLQGPGTELDGPESMTDMFVRDIEHGIADTGVKAAVLKCAT
                                    ****:*  *   ***  *.* * *::*******:******:**.:*****

MUL_1150|M.ulcerans_Agy99           DEPGITPGVERVLRAVAQTHKRTGVPISTHTHAGLRRGLEQQRIFEEEGV
MMAR_0487|M.marinum_M               DEPGITPGVERVLRAVAQTHKRTGVPISTHTHAGLRRGLEQQRIFEEEGV
Mb0235c|M.bovis_AF2122/97           DEPGLTPGVERVLRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGV
Rv0230c|M.tuberculosis_H37Rv        DEPGLTPGVERVLRAVAQAHKRTGAPISTHTHAGLRRGLDQQRIFAEEGV
MAV_4940|M.avium_104                DAPGVTPGVERVLRAVAQAHKRTGVPISTHTHAGLRRGLDQQRIFEEEGV
MSMEG_0320|M.smegmatis_MC2_155      DEPGVTPGVERVLRAVAAAHRQTGVPISTHTHAATRRGLEQQRVFAEEGV
TH_1316|M.thermoresistible__bu      DKPGVTAGVDRVLRAVAQAHRRTGVPISTHTHAASRRGLDQQRVFAEEGV
                                    * **:*.**:******* :*::**.********. ****:***:* ****

MUL_1150|M.ulcerans_Agy99           DLSRVIIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDLILPFEDRVNIVA
MMAR_0487|M.marinum_M               DLSRVIIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDLILPFEDRVSIVA
Mb0235c|M.bovis_AF2122/97           ELSRVVIGHCGDSTDVGYLEELIAAGSYLGMDRFGVDVISPFQDRVNIVA
Rv0230c|M.tuberculosis_H37Rv        DLSRVVIGHCGDSTDVGYLEELIAAGSYLGMDRFGVDVISPFQDRVNIVA
MAV_4940|M.avium_104                DLSRVVIGHSGDSTDVGYLEELIAAGSYLGMDRFGIDAISPFEDRVNIVA
MSMEG_0320|M.smegmatis_MC2_155      DLTRVIIGHCGDTTDIGYLEELIANGSYIGMDRFGVDVFLPFEQRVATVA
TH_1316|M.thermoresistible__bu      DLSRVVIGHCGDTTDIGYLEQLIANGSYIGMDRFGVDTFLSFEDRVNTVA
                                    :*:**:***.**:**:****:*** ***:******:* : .*::**  **

MUL_1150|M.ulcerans_Agy99           TMCERGHADKMVLSHDANCYFDALPEELTAVATPNWHYLHIHNDVIPALK
MMAR_0487|M.marinum_M               TMCERGHADKMVLSHDANCYFDALPEELTAVATPNWHYLHIHNDVIPALK
Mb0235c|M.bovis_AF2122/97           RMCERGHADKMVLSHDACCYFDALPEELVPVAMPNWHYLHIHNDVIPALK
Rv0230c|M.tuberculosis_H37Rv        RMCERGHADKMVLSHDACCYFDALPEELVPVAMPNWHYLHIHNDVIPALK
MAV_4940|M.avium_104                QMCERGHADKMVLSHDANCYFDALPEELVPQVMPNWHYLHIHNDVIPALK
MSMEG_0320|M.smegmatis_MC2_155      TMCERGHAERMVLSHDTWCYFDALPDELTTAALPNSHYLHIHNDVIPALR
TH_1316|M.thermoresistible__bu      KMCELGYADRMVLSHDAHCYFDWLPEQLVAAGLPNWHYLHIHDDVIPALK
                                     *** *:*::******: **** **::*..   ** ******:******:

MUL_1150|M.ulcerans_Agy99           ERGVTHEQVHTMLVDNPRRIFERQGGYQ
MMAR_0487|M.marinum_M               ERGVTDEQVHTMLVDNPRRIFERQGGYQ
Mb0235c|M.bovis_AF2122/97           QHGVTDEQLHTMLVDNPRRIFERQGGYQ
Rv0230c|M.tuberculosis_H37Rv        QHGVTDEQLHTMLVDNPRRIFERQGGYQ
MAV_4940|M.avium_104                QRGVTDEQLHTMLVDNPRRIFERQGPYG
MSMEG_0320|M.smegmatis_MC2_155      QRGVTDEQITTMLVDNPRRIFEHKGGY-
TH_1316|M.thermoresistible__bu      QRGVTDEQLTTMLVDNPRRIFETQGGY-
                                    ::***.**: ************ :* *