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MAGPVGLPVIDTMIGFPHEGSAQYDFIRKQTKDRESKENFEFPVEYMFKDVPKGLPTDDPVSLVLQQMDR FNIEKAMIGVREDSAQLALKTFPDRFIPSGAIADPNDVMGSVAAIRREYEQFGIRATSVFPAGTFPQVPI DDPKMYPIYATCVELGIPIFVCAGIPGPRLPFRLQEVSRIDIVMFDFPDLVFVTRHGCEPWEELAVKLML KWPNLYYSTSAFAPKYYPNAIIDYANSRGADKVLYAGYFPMGLSLERIFSELPKVGLKDEVWPKFLYGNA ARILGLTG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4957 | - | - | 100% (288) | hypothetical protein MUL_4957 |
| M. ulcerans Agy99 | MUL_3876 | - | 4e-25 | 28.91% (256) | metal-dependent hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3540c | - | 8e-21 | 28.93% (242) | hypothetical protein Mb3540c |
| M. gilvum PYR-GCK | Mflv_4348 | - | 4e-26 | 28.69% (237) | amidohydrolase 2 |
| M. tuberculosis H37Rv | Rv3510c | - | 8e-21 | 28.93% (242) | hypothetical protein Rv3510c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0140 | - | 1e-169 | 99.31% (288) | hypothetical protein MMAR_0140 |
| M. avium 104 | MAV_1593 | - | 5e-27 | 38.89% (144) | amidohydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_2232 | - | 1e-28 | 30.90% (233) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_1218 | - | 6e-29 | 31.90% (232) | amidohydrolase family protein |
| M. vanbaalenii PYR-1 | Mvan_1996 | - | 6e-25 | 27.85% (237) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1593|M.avium_104 --M----KAIDCLVNVHFG-------------ETEKQPTWMLKVRDDYFK
TH_1218|M.thermoresistible__bu MTR----KVLDCLVNVHFG-------------EAEMQPAWMEKVRDDYFK
Mflv_4348|M.gilvum_PYR-GCK MSD----RVIDCLVNVHFG-------------ETANQPEFMLKVRDDYFK
Mvan_1996|M.vanbaalenii_PYR-1 MTH----KVIDCLVNVHFG-------------ETAKQPEFMLKVRDDYFK
MSMEG_2232|M.smegmatis_MC2_155 MTESPAGRAIDCLANVHFG-------------ETQNQPAFMTKVRDDYFK
Mb3540c|M.bovis_AF2122/97 -------MTIDVWMQHPTQ-------------RFLHGDMFASLRR---WT
Rv3510c|M.tuberculosis_H37Rv -------MTIDVWMQHPTQ-------------RFLHGDMFASLRR---WT
MUL_4957|M.ulcerans_Agy99 MAGPVGLPVIDTMIGFPHEGSAQYDFIRKQTKDRESKENFEFPVEYMFKD
MMAR_0140|M.marinum_M MAGPVGLPVIDTMIGFPHEGSAQYDFIRKQTKDRESKENFEFPVEYMFKD
.:* : .
MAV_1593|M.avium_104 GPASMFAPVELSELIDEMDAQGVRKAILMDNLAK------PSVTARKFVE
TH_1218|M.thermoresistible__bu GPEAMFAPVDLAELLDEMDEQGVQKAILMDNLSK------PSVTARKFVE
Mflv_4348|M.gilvum_PYR-GCK GPQSLYDQVELPALLDEMAEHGVEKAILMDNLVK------PSVTARKFAE
Mvan_1996|M.vanbaalenii_PYR-1 GPQSLYEQVELPALLDEMAEHGVEKAILMDNLVK------PSVTARKFVE
MSMEG_2232|M.smegmatis_MC2_155 GPKSMYDPIDLGALLEEMDANGVERAILMDNLTK------PSVTARKFVE
Mb3540c|M.bovis_AF2122/97 GGSIPETDIPIEATVSSMDAGGVTLGLLSAWRGPNGQDLISNDAVAEWVR
Rv3510c|M.tuberculosis_H37Rv GGSIPETDIPIEATVSSMDAGGVTLGLLSAWRGPNGQDLISNDAVAEWVR
MUL_4957|M.ulcerans_Agy99 VPKGLPTDDPVSLVLQQMDRFNIEKAMIGVREDS----------AQLALK
MMAR_0140|M.marinum_M VPKGLPTDDPVSLVLQQMDRFNIEKAMIGVREDS----------AQLALK
: :..* .: .:: . .
MAV_1593|M.avium_104 DKPERFALAMGGVNLLRPIPSLRELGAVVADLPVAYAAVGPSFWGDGQYP
TH_1218|M.thermoresistible__bu ARPDRFALAMGGVNLLRPIPSLRELAAVAADLPVVYAVVGPSFWGDGQYP
Mflv_4348|M.gilvum_PYR-GCK ERPDKFALAIGGVNLLRPMPSLRELSSVVADLPVAYAAVGPSFWGDGMYP
Mvan_1996|M.vanbaalenii_PYR-1 ERPDKFALAVGGVNLLRPMPSLRELAAVVADLPVAYAAVGPSFWGDGMYP
MSMEG_2232|M.smegmatis_MC2_155 AHPERFALAMGGVNLLRPIPSLRELAAAVRDLPVAYAVVGPSFWGDGQYP
Mb3540c|M.bovis_AF2122/97 LYPNRFAG-LAAVDLDRPMAAVRELRRRVGEGFVGLRVV-PWLWG---AP
Rv3510c|M.tuberculosis_H37Rv LYPNRFAG-LAAVDLDRPMAAVRELRRRVGEGFVGLRVV-PWLWG---AP
MUL_4957|M.ulcerans_Agy99 TFPDRFIPSGAIADPNDVMGSVAAIRREYEQFGIRATSVFPAGTFP-QVP
MMAR_0140|M.marinum_M TFPDRFIPSGAIADPNDVMGSVAAIRREYEQFGIRATSVFPAGTFP-QVP
*::* . .: : :: : : : * * *
MAV_1593|M.avium_104 PSDAVYYPLYTKCAELELPLCVNTGIPGPPIPGEVQNPI-HLDRVCVRFP
TH_1218|M.thermoresistible__bu PSDAVYYPLYTKCAELELPLCVNTGIPGPPIPGEVQNPI-HLDRVCVRFP
Mflv_4348|M.gilvum_PYR-GCK PSDAVYYPLYTKCAELGLPLCINTGLPGPPIPGEVQNPI-HLDRVCVRFP
Mvan_1996|M.vanbaalenii_PYR-1 PSDAVYYPLYTKCAELELPLCINTGLPGPPIPGEVQNPI-HLDRVCVRFP
MSMEG_2232|M.smegmatis_MC2_155 PSDAVYYPLYTKCAELDLPLCVNTGLPGPPIPGEVQNPI-HLDRVCVRFP
Mb3540c|M.bovis_AF2122/97 PTDRRYYPLFAECVQSAVPFCTQVGHTGPLRPSETGRPIPYIDQVALDFP
Rv3510c|M.tuberculosis_H37Rv PTDRRYYPLFAECVQSAVPFCTQVGHTGPLRPSETGRPIPYIDQVALDFP
MUL_4957|M.ulcerans_Agy99 IDDPKMYPIYATCVELGIPIFVCAGIPGPRLPFRLQEVS-RIDIVMFDFP
MMAR_0140|M.marinum_M IDDPKMYPIYATCVELGIPIFVCAGIPGPRLPFRPQEVS-RIDIVMFDFP
* **::: *.: :*: .* .** * . . :* * . **
MAV_1593|M.avium_104 ELKLCMIHGADPWWDVAIRLLLKYANLRLMTSAWSPKRLPESLLHYMRTR
TH_1218|M.thermoresistible__bu ELRLCMIHGADPWWDIAIRLLIKYQNLRLMTSAWSPKRLPNSLLHYMRTR
Mflv_4348|M.gilvum_PYR-GCK ELKLCMIHGADPWWDVAIRLLIKYANLRIMTSAWSPKRLPDSLLHYMRTR
Mvan_1996|M.vanbaalenii_PYR-1 ELKLCMIHGADPWWDVAIRLLIKYANLRIMTSAWSPKRLPDSLLHFMRTR
MSMEG_2232|M.smegmatis_MC2_155 ELRLCMIHGADPWWDIAIRMLIKYKNLRLMTSAWSPKRLPESLLHYMRTR
Mb3540c|M.bovis_AF2122/97 ELVIVCGHVGYPWTEEMVAVARKHENVYIDTSAYTIKRLPGKLVRFMKTD
Rv3510c|M.tuberculosis_H37Rv ELVIVCGHVGYPWTEEMVAVARKHENVYIDTSAYTIKRLPGKLVRFMKTD
MUL_4957|M.ulcerans_Agy99 DLVFVTRHGCEPWEELAVKLMLKWPNLYYSTSAFAPKYYPNAIIDYANSR
MMAR_0140|M.marinum_M DLVFVTRHGCEPWEELAVKLMLKWPNLYYSTSAFAPKYYPKAIIDYANSR
:* : * ** : : : * *: ***:: * * :: : .:
MAV_1593|M.avium_104 -GQDKVIFASDWPV-LKMHRVVPEAAGLDLPADVLENYLYNNAHEFFFGG
TH_1218|M.thermoresistible__bu -GPNKVIFGSDWPV-LTMRRVVPEAYALDLPSEVLDNYLYNNAAEFFFGG
Mflv_4348|M.gilvum_PYR-GCK -GKNKVIFASDWPV-LRQSRVVPEALALDLPPDVLDNYLYNNANDFFFGT
Mvan_1996|M.vanbaalenii_PYR-1 -GKNKVIFASDWPV-LRQSRVVPEAVALDLPPDVLDNYLYNNANDFFFGA
MSMEG_2232|M.smegmatis_MC2_155 -GPDKIIFASDFPV-LRMNRVVPEARALDLPPDVLDNYLYHNAAEFFFGG
Mb3540c|M.bovis_AF2122/97 TGQRKVLFGTNYPM-IAHTHALTGLDELGLSDEARRDFLHGNAVRVFKLD
Rv3510c|M.tuberculosis_H37Rv TGQRKVLFGTNYPM-IAHTHALTGLDELGLSDEARRDFLHGNAVRVFKLD
MUL_4957|M.ulcerans_Agy99 -GADKVLYAGYFPMGLSLERIFSELPKVGLKDEVWPKFLYGNAARILGLT
MMAR_0140|M.marinum_M -GADKVLYAGYFPMGLSLERIFSELPKVGLKDEVWPKFLYGNAARILGLT
* *:::. :*: : : .. :.* :. .:*: ** .:
MAV_1593|M.avium_104 HKEG---
TH_1218|M.thermoresistible__bu PEQER--
Mflv_4348|M.gilvum_PYR-GCK DEQEI--
Mvan_1996|M.vanbaalenii_PYR-1 AEQEI--
MSMEG_2232|M.smegmatis_MC2_155 RQPQEF-
Mb3540c|M.bovis_AF2122/97 PRGKVQT
Rv3510c|M.tuberculosis_H37Rv PRGKVQT
MUL_4957|M.ulcerans_Agy99 G------
MMAR_0140|M.marinum_M G------