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ADRAKGHSTRYSAYTGGPDPLAPPVDLREALEQIGQDVMAGTSPRRALSELLRRGTKSMPGADRLASEAN RRRRELLRRNNLDGTLQEIKKLLDEAVLAERKELARALDDDARFSELQLEALPPSPAKAVQELSEYDWRS GEAREKYDQIKDLLGRELLDQRFAGMKQALEGATDEDRQRVNEMLDDLNNLLDKHARGQDTQQDFQDFMD KHGEFFPENPSNVEELLDSLAKRAAAAQRFRNSLSQEQRDELDALAQQAFGSPSLMQALNRLDAHLQEAR PGEDWTGQQRFSGDNPFGMGEGTQALADIAELEQLAEQLSQAYPGATMDDVDLDALARQLGDQAAIDART LAELERALVNQGFFDRGSDGQWRLSPKAMRRLGETALRDVVQQLSGRRGERDHRRAGAAGELTGATRPWQ FGDTEPWHISRTLTNAVLRQAGTAPPGGAAGPIRITVDDVEVSETETRTQAAVALLVDTSFSMVMENRWL PMKRTALALNHLVCTRFRSDALQIIAFGRYARTVTAAELTGLEGVYEQGTNLHHALALAGRHLRRHPNAQ PVVLVVTDGEPTAHLEDFSGEGAGSAVFFDYPPHPRTIAHTVRGFDDMARLDAQITIFRLGSDRGLARFI DQVARRVEGRVVEPDLDGLGAAVVGDYLRSRRRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4710 | - | - | 100% (665) | hypothetical protein MUL_4710 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0984 | - | 0.0 | 88.94% (660) | hypothetical protein Mb0984 |
| M. gilvum PYR-GCK | Mflv_1878 | - | 0.0 | 86.19% (659) | von Willebrand factor, type A |
| M. tuberculosis H37Rv | Rv0959 | - | 0.0 | 88.94% (660) | hypothetical protein Rv0959 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4540 | - | 0.0 | 98.95% (665) | hypothetical protein MMAR_4540 |
| M. avium 104 | MAV_1084 | - | 0.0 | 92.19% (640) | von Willebrand factor, type A |
| M. smegmatis MC2 155 | MSMEG_5511 | - | 0.0 | 87.01% (662) | von Willebrand factor, type A |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4853 | - | 0.0 | 86.40% (662) | von Willebrand factor, type A |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0984|M.bovis_AF2122/97 MAKSDGDDPLRPASPRLRSSRRHSLRYSAYTGGPDPLAPPVDLRDALEQI
Rv0959|M.tuberculosis_H37Rv MAKSDGDDPLRPASPRLRSSRRHSLRYSAYTGGPDPLAPPVDLRDALEQI
MUL_4710|M.ulcerans_Agy99 ---------------MADRAKGHSTRYSAYTGGPDPLAPPVDLREALEQI
MMAR_4540|M.marinum_M ---------------MADRAKGHSTRYSAYTGGPDPLAPPVDLREALEQI
MAV_1084|M.avium_104 ----------------------------------------MDLREALEQI
Mflv_1878|M.gilvum_PYR-GCK --------------------MSRTSRYSRYTGGPDPLAPPVDLRDALEAI
Mvan_4853|M.vanbaalenii_PYR-1 -----------MAK------HVRLSRYSRYTGGPDPLAPPVDLREALEAI
MSMEG_5511|M.smegmatis_MC2_155 -----------MADNASGRGHGHTSRYSRYTGGPDPLAPPIDLREALEQI
:***:*** *
Mb0984|M.bovis_AF2122/97 GQDVMAGASPRRALSELLRRGTRNLTGADRLAAEVNRRRRELLRRNNLDG
Rv0959|M.tuberculosis_H37Rv GQDVMAGASPRRALSELLRRGTRNLTGADRLAAEVNRRRRELLRRNNLDG
MUL_4710|M.ulcerans_Agy99 GQDVMAGTSPRRALSELLRRGTKSMPGADRLASEANRRRRELLRRNNLDG
MMAR_4540|M.marinum_M GQDVMAGTSPRRALSELLRRGTKSMPGADRLASEANRRRRELLRRNNLDG
MAV_1084|M.avium_104 GQDVMAGTSPRRALSELLRRGTKNMPGADRLAAEANRRRRELLRRNNLDG
Mflv_1878|M.gilvum_PYR-GCK GQDVMEGTSPRRALSELLRRGTKNMPGADKLAAEANRRRRELLQRNNLDG
Mvan_4853|M.vanbaalenii_PYR-1 GQDVMEGTSPRRALSEMLRRGTQNMPGADKLAAEANRRRRELLQRNNLDG
MSMEG_5511|M.smegmatis_MC2_155 GQNVMEGSSPRRALSELMRRGTQNMRGADRLAAEANRRRRELLQRNNLDG
**:** *:********::****:.: ***:**:*.********:******
Mb0984|M.bovis_AF2122/97 TLQEIKKLLDEAVLAERKELARALDDDARFAELQLDALPASPAKAVQELA
Rv0959|M.tuberculosis_H37Rv TLQEIKKLLDEAVLAERKELARALDDDARFAELQLDALPASPAKAVQELA
MUL_4710|M.ulcerans_Agy99 TLQEIKKLLDEAVLAERKELARALDDDARFSELQLEALPPSPAKAVQELS
MMAR_4540|M.marinum_M TLQEIKKLLDEAVLAERKELARALDDDARFSELQLEALPPSPAKAVQELS
MAV_1084|M.avium_104 TLQEIKKLLDEAVLAERKELARALDDDARFGELQLDALPASPAKAVQELS
Mflv_1878|M.gilvum_PYR-GCK TLTEIKKLLDEAVLAERKELARALDDDARFGELQLESLSPSPAKAVQELA
Mvan_4853|M.vanbaalenii_PYR-1 TLADIKKLLDEAVLAERKELARALDDDARFGELQLNSLSPSPAKAVQELS
MSMEG_5511|M.smegmatis_MC2_155 TLQEIKKLLDEAVLAERKELARALDDDARFGELQLDALSPSPAKAVQELA
** :**************************.****::*..*********:
Mb0984|M.bovis_AF2122/97 EYRWRSGQAREKYEQIKDLLGRELLDQRFAGMKQALAGATDDDRRRVTEM
Rv0959|M.tuberculosis_H37Rv EYRWRSGQAREKYEQIKDLLGRELLDQRFAGMKQALAGATDDDRRRVTEM
MUL_4710|M.ulcerans_Agy99 EYDWRSGEAREKYDQIKDLLGRELLDQRFAGMKQALEGATDEDRQRVNEM
MMAR_4540|M.marinum_M EYDWRSGEAREKYDQIKDLLGRELLDQRFAGMKQALEGATDEDRERVNEM
MAV_1084|M.avium_104 EYNWRSSEAREKYDQIKDLLGREMLDQRFAGMKQALQGATDEDRQRVSDM
Mflv_1878|M.gilvum_PYR-GCK EYDWRSAEAREKYDQIKDLMGREMLDQRFAGMKEALENATDEDRQRVNDM
Mvan_4853|M.vanbaalenii_PYR-1 DYDWRSPEAREKYDQIKDLLGREMLDQRFAGMKEALENATDEDRQRVNDM
MSMEG_5511|M.smegmatis_MC2_155 EYDWRSQEAREKYEQIKDLMGREMLDQRFAGMKQALENATDEDRQRVNDM
:* *** :*****:*****:***:*********:** .***:**.**.:*
Mb0984|M.bovis_AF2122/97 LDDLNDLLDKHARGEDTQRDFDEFMTKHGEFFPENPRNVEELLDSLAKRA
Rv0959|M.tuberculosis_H37Rv LDDLNDLLDKHARGEDTQRDFDEFMTKHGEFFPENPRNVEELLDSLAKRA
MUL_4710|M.ulcerans_Agy99 LDDLNNLLDKHARGQDTQQDFQDFMDKHGEFFPENPSNVEELLDSLAKRA
MMAR_4540|M.marinum_M LDDLNNLLDKHARGQDTQQDFQDFMDKHGEFFPENPSNVEELLDSLAKRA
MAV_1084|M.avium_104 LNDLNDLLDKHAKGQDSQQDFDDFMAKHGEFFPESPRNVEELLDSLAKRA
Mflv_1878|M.gilvum_PYR-GCK LDDLNELLDKHARGEDTDQGFRDFMAKHGEFFPENPQNIDELLDSLAQRA
Mvan_4853|M.vanbaalenii_PYR-1 LDDLNDLLDKHAKGQDSPQDFQDFMAKHGQFFPENPKNIDELLDSLAKRA
MSMEG_5511|M.smegmatis_MC2_155 LDDLNNLLDKHAAGQDTQQDFQDFMDKHGEFFPENPQNIDELLDSLAKRA
*:***:****** *:*: :.* :** ***:****.* *::*******:**
Mb0984|M.bovis_AF2122/97 AAAQRFRNSLSQEQRDELDALAQQAFGSPALMRALDRLDAHLQAARPGED
Rv0959|M.tuberculosis_H37Rv AAAQRFRNSLSQEQRDELDALAQQAFGSPALMRALDRLDAHLQAARPGED
MUL_4710|M.ulcerans_Agy99 AAAQRFRNSLSQEQRDELDALAQQAFGSPSLMQALNRLDAHLQEARPGED
MMAR_4540|M.marinum_M AAAQRFRNSLSQEQRDELDALAQQAFGSPSLMQALNRLDAHLQEARPGED
MAV_1084|M.avium_104 AAAQRFRNSLSAEQRAELDALAQQAFGSPDLMQALNRLDAHLQAARPGED
Mflv_1878|M.gilvum_PYR-GCK AAAQRFRNSLTEQQRAELDSLAQQAFGSPSLMNALNRLDSHLQAARPGED
Mvan_4853|M.vanbaalenii_PYR-1 AAAQRFRNSLSEQQRAELDALAQQAFGSPSLMNALDRLDAHLQSARPGED
MSMEG_5511|M.smegmatis_MC2_155 AAAQRFRNSLSPDQRAELDALAQQAFGSPSLMNALNRLDAHLQSARPGED
**********: :** ***:********* **.**:***:*** ******
Mb0984|M.bovis_AF2122/97 WTGSQQFSGDNPFGMGEGTQALADIAELEQLAEQLSQSYPGASMDDVDLD
Rv0959|M.tuberculosis_H37Rv WTGSQQFSGDNPFGMGEGTQALADIAELEQLAEQLSQSYPGASMDDVDLD
MUL_4710|M.ulcerans_Agy99 WTGQQRFSGDNPFGMGEGTQALADIAELEQLAEQLSQAYPGATMDDVDLD
MMAR_4540|M.marinum_M WTGQQQFSGDNPFGMGEGTQALADIAELEQLAEQLSQAYPGATMDDVDLD
MAV_1084|M.avium_104 WGGSEQFSGDNPFGMGEGTQALADIAELEQLAEQLSQSYPGATMDDVDLD
Mflv_1878|M.gilvum_PYR-GCK WSGSQRFSGDDPLGMGEGAQALADIAELEQLAEQLSQSYSGASMDDVDLD
Mvan_4853|M.vanbaalenii_PYR-1 WTGSQRFSGDDPLGMGEGAQALADIAELEQLAEQLSQSYSGATMDDVDLD
MSMEG_5511|M.smegmatis_MC2_155 WNGAQRFSGDDPLGMGEGAQALADIAELEQLADALSQSYAGATMDDVDLE
* * ::****:*:*****:*************: ***:*.**:******:
Mb0984|M.bovis_AF2122/97 ALARQLGDQAAVDARTLAELERALVNQGFLDRGSDGQWRLSPKAMRRLGE
Rv0959|M.tuberculosis_H37Rv ALARQLGDQAAVDARTLAELERALVNQGFLDRGSDGQWRLSPKAMRRLGE
MUL_4710|M.ulcerans_Agy99 ALARQLGDQAAIDARTLAELERALVNQGFFDRGSDGQWRLSPKAMRRLGE
MMAR_4540|M.marinum_M ALARQLGDQAAIDARTLAELERALVNQGFFDRGSDGQWRLSPKAMRRLGE
MAV_1084|M.avium_104 ALARQLGDQAAVDARTLAELERALVNQGFLDRGSDGQWRLSPKAMRRLGE
Mflv_1878|M.gilvum_PYR-GCK MLARQLGDEAAVDARTLSELERALMNQGFLDRGSDGQWRLSPKAMRQLGQ
Mvan_4853|M.vanbaalenii_PYR-1 MLARQLGDEAAVNARTLAELERALMNQGFLDRGSDGQWRLSPKAMRQLGQ
MSMEG_5511|M.smegmatis_MC2_155 ALARQLGDEAAVDARTLAELERALVNQGFLDRGSDGQWRLSPKAMRQLGQ
*******:**::****:******:****:****************:**:
Mb0984|M.bovis_AF2122/97 TALRDVAQQLSGRHGERDHRRAGAAGELTGATRPWQFGDTEPWHVARTLT
Rv0959|M.tuberculosis_H37Rv TALRDVAQQLSGRHGERDHRRAGAAGELTGATRPWQFGDTEPWHVARTLT
MUL_4710|M.ulcerans_Agy99 TALRDVVQQLSGRRGERDHRRAGAAGELTGATRPWQFGDTEPWHISRTLT
MMAR_4540|M.marinum_M TALRDVVQQLSGRRGERDHRRAGAAGELTGATRPWQFGDTEPWHISRTLT
MAV_1084|M.avium_104 TALRDVAQQLSGRRGERDHRRAGAAGELTGATRPWQFGDTEPWNISRTLT
Mflv_1878|M.gilvum_PYR-GCK AALRDVAQQLSGRHGERDTRRAGAAGELTGATRPWQFGDTEPWNVTRTLT
Mvan_4853|M.vanbaalenii_PYR-1 AALRDVAQQLSGRHGERDTRRAGAAGELTGATRPWQFGDTEPWNVTRTVT
MSMEG_5511|M.smegmatis_MC2_155 TALRDVAQQLSGRHGERDTRRAGAAGELTGATRPWQFGDTEPWNVTRTVT
:*****.******:**** ************************:::**:*
Mb0984|M.bovis_AF2122/97 NAVLRQAAAVH-----------DRIRITVEDVEVAETETRTQAAVALLVD
Rv0959|M.tuberculosis_H37Rv NAVLRQAAAVH-----------DRIRITVEDVEVAETETRTQAAVALLVD
MUL_4710|M.ulcerans_Agy99 NAVLRQAGTAPP------GGAAGPIRITVDDVEVSETETRTQAAVALLVD
MMAR_4540|M.marinum_M NAVLRQAGTAPS------GGGAGPIRITVDDVEVSETETRTQAAVALLVD
MAV_1084|M.avium_104 NAVLRQAGTATL------DGPDGRLKITVDDVEVSETETRTQAAVALLVD
Mflv_1878|M.gilvum_PYR-GCK NAVLREAGT-------AKDRPGGRLRITVDDVEISETETRTQAAVALLVD
Mvan_4853|M.vanbaalenii_PYR-1 NAVLRTAGTNAVLREAGTGETAGPIRITVDDVEISETETRTQAAVALLVD
MSMEG_5511|M.smegmatis_MC2_155 NAVLRQAGT---------GLVERPIRFAVDDVEISETETRTQACVALLVD
***** *.: ::::*:***::********.******
Mb0984|M.bovis_AF2122/97 TSFSMVMENRWLPMKRTALALHHLVCTRFRSDALQIIAFGRYARTVTAAE
Rv0959|M.tuberculosis_H37Rv TSFSMVMENRWLPMKRTALALHHLVCTRFRSDALQIIAFGRYARTVTAAE
MUL_4710|M.ulcerans_Agy99 TSFSMVMENRWLPMKRTALALNHLVCTRFRSDALQIIAFGRYARTVTAAE
MMAR_4540|M.marinum_M TSFSMVMENRWLPMKRTALALNHLVCTRFRSDALQIIAFGRYARTVTAAE
MAV_1084|M.avium_104 TSFSMVMENRWLPMKQTALALNHLVCTRFRSDALQIIAFGRYARTVTAAE
Mflv_1878|M.gilvum_PYR-GCK TSFSMVMENRWLPMKRTALALNHLVSTRFRSDALQIVAFGRYARTVTAAE
Mvan_4853|M.vanbaalenii_PYR-1 TSFSMVMENRWLPMKRTALALNHLVSTRFRSDALQIVAFGRYARTVTAAE
MSMEG_5511|M.smegmatis_MC2_155 TSFSMVMENRWLPMKRTALALNHLVSTRFRSDALQIIAFGRYARTVSAAE
***************:*****:***.**********:*********:***
Mb0984|M.bovis_AF2122/97 LTGLAGVYEQGTNLHHALALAGRHLRRHAGAQPVVLVVTDGEPTAHLEDF
Rv0959|M.tuberculosis_H37Rv LTGLAGVYEQGTNLHHALALAGRHLRRHAGAQPVVLVVTDGEPTAHLEDF
MUL_4710|M.ulcerans_Agy99 LTGLEGVYEQGTNLHHALALAGRHLRRHPNAQPVVLVVTDGEPTAHLEDF
MMAR_4540|M.marinum_M LTGLEGVYEQGTNLHHALALAGRHLRRHPNAQPVVLVVTDGEPTAHLEDF
MAV_1084|M.avium_104 LTGLEGVYEQGTNLHHALALAGRHLRRHPNAQPVVLVVTDGEPTAHLEDF
Mflv_1878|M.gilvum_PYR-GCK LTGLEGVYEQGTNLHHALALATRHLRRHPNAQPVILVVTDGEPTAHLEDF
Mvan_4853|M.vanbaalenii_PYR-1 LTGLEGVYEQGTNLHHALALATRHLRRHPNAQPVVLVVTDGEPTAHLEDF
MSMEG_5511|M.smegmatis_MC2_155 LTALEGVYEQGTNLHHALALASRHLRRHPNAQPVVLVVTDGEPTAHLENF
**.* **************** ******..****:*************:*
Mb0984|M.bovis_AF2122/97 -DGD--GTSVFFDYPPHPRTIAHTVRGFDDMARLGAQVTIFRLGSDPGLA
Rv0959|M.tuberculosis_H37Rv -DGD--GTSVFFDYPPHPRTIAHTVRGFDDMARLGAQVTIFRLGSDPGLA
MUL_4710|M.ulcerans_Agy99 -SGEGAGSAVFFDYPPHPRTIAHTVRGFDDMARLDAQITIFRLGSDRGLA
MMAR_4540|M.marinum_M -AGEGAGSTVFFDYPPHPRTIAHTVRGFDDMARLGAQITIFRLGSDRGLA
MAV_1084|M.avium_104 -EGE--GTTVFFDYPPHPRTIAHTVRGFDEMARLGAQITIFRLGSDPGLA
Mflv_1878|M.gilvum_PYR-GCK --DGDGRSSVFFDYPPHPRTIAHTVRGFDEVARLGAQVTIFRLGSDPGLA
Mvan_4853|M.vanbaalenii_PYR-1 --DGDGRSAVFFDYPPHPRTIAHTVKGFDEVARMGAQVTIFRLGSDPGLA
MSMEG_5511|M.smegmatis_MC2_155 RISEDEGAQVFFDYPPHPRTIAHTVRGFDEVARLGAQVTIFRLGSDPGLA
. : ****************:***::**:.**:******** ***
Mb0984|M.bovis_AF2122/97 RFIDQVARRVQGRVVVPDLDGLGAAVVGDYLRFRRR-
Rv0959|M.tuberculosis_H37Rv RFIDQVARRVQGRVVVPDLDGLGAAVVGDYLRFRRR-
MUL_4710|M.ulcerans_Agy99 RFIDQVARRVEGRVVEPDLDGLGAAVVGDYLRSRRRR
MMAR_4540|M.marinum_M RFIDQVARRVEGRVVEPDLDGLGAAVVGDYLRSRRRR
MAV_1084|M.avium_104 RFIDQVARRVEGRVVVPDLDGLGAAVVGDYLRSRRRR
Mflv_1878|M.gilvum_PYR-GCK RFIDQVARRVGGRVVVPDLDGLGAAVVGDYLSAKRRR
Mvan_4853|M.vanbaalenii_PYR-1 RFIDQVARRVGGRVVVPDLDGLGAAVVGDYLSAKRRR
MSMEG_5511|M.smegmatis_MC2_155 RFIDQVARRVQGRVVVPDLDGLGAAVVGDYLRSRRR-
********** **** *************** :**