For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RSVEEQQARISAAAVAPRPIRVAIAEAQGLMCAEEVVTERPLPGFDQAAIDGYAVRSVDVMGVGQDLASG AAEFFVDDGSAISRDAVTLPVMGTIEAGARTPTRLQPKQVVRVQTGAPLPTLADAVLPLRWTDGGMNRVR VLRGAPSGAYVRHAGDDVQPGDVAVRSGTIIGAAQVGLLAAVGRERVLVHPRPRLSVMAVGGELVDISRT PGNGQVYDVNSYALAAAGRDAGAEVNRVGIVSNDPNQLGEIVEGQINRAEVVVIAGGVGGAAAEAVRSVL SELGDMEVVRIAMHPGSVQGFGQLGRDRVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRQPMRRIVQAR TLSPITSVAGRKGYLRGQLMRDQESGEYLVQALGGAPGASSHLLATLAEANCLVVVPTGAEQIRTGEIVD VAFLAQHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4692 | moeA1 | - | 100% (429) | molybdopterin biosynthesis protein MoeA1 |
| M. ulcerans Agy99 | MUL_1390 | moeA2 | 4e-62 | 36.83% (429) | molybdopterin biosynthesis protein MoeA2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1021 | moeA1 | 0.0 | 91.84% (429) | molybdopterin biosynthesis protein MoeA1 |
| M. gilvum PYR-GCK | Mflv_1898 | - | 0.0 | 83.68% (429) | molybdenum cofactor synthesis domain-containing protein |
| M. tuberculosis H37Rv | Rv0994 | moeA1 | 0.0 | 91.61% (429) | molybdopterin biosynthesis protein MoeA1 |
| M. leprae Br4923 | MLBr_00183 | moeA | 0.0 | 86.08% (431) | putative molybdopterin biosynthesis protein |
| M. abscessus ATCC 19977 | MAB_1087 | - | 0.0 | 77.52% (436) | molybdopterin biosynthesis protein MoeA1 |
| M. marinum M | MMAR_4520 | moeA1 | 0.0 | 98.60% (429) | molybdopterin biosynthesis protein MoeA1 |
| M. avium 104 | MAV_1103 | - | 0.0 | 86.01% (429) | molybdopterin biosynthesis protein moeA |
| M. smegmatis MC2 155 | MSMEG_5470 | - | 0.0 | 83.45% (429) | molybdopterin biosynthesis protein MoeA 1 |
| M. thermoresistible (build 8) | TH_0939 | moeA | 0.0 | 82.13% (414) | PROBABLE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEA1 |
| M. vanbaalenii PYR-1 | Mvan_4832 | - | 0.0 | 84.15% (429) | molybdenum cofactor synthesis domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4692|M.ulcerans_Agy99 MRSVEEQQARISAAAVAPRPIRVAIAEAQGLMCAEEVVTERPLPGFDQAA
MMAR_4520|M.marinum_M MRSVEEQQARISAAAVAPRPIRVAIAEAQGLMCAEEVVTERPLPGFDQAA
Mb1021|M.bovis_AF2122/97 MRSVEEQQARISAAAVAPRPIRVAIAEAQGLMCAEEVVTERPMPGFDQAA
Rv0994|M.tuberculosis_H37Rv MRSVEEQQARISAAAVAPRPIRVAIAEAQGLMCAEEVVTERPMPGFDQAA
MLBr_00183|M.leprae_Br4923 MRSVEEQQARILAAAVVPRPVRVAIAEAQGLMCAEEVMTERPLPGFDQAA
MAV_1103|M.avium_104 MRSVEEQQARITAAAVAPRPIRVAIAEAQGLMCAEEVVTERPMPGFDQAA
Mflv_1898|M.gilvum_PYR-GCK MRSVEEQQARVAAAAVAPRPVRVAIAEAQGLMCAEEVVTERPLPGFDQAA
Mvan_4832|M.vanbaalenii_PYR-1 MRSVEDQQARVAAAAVAPRPVRVAIAEAQGLMCAEEVVTERPMPGFDQAA
MSMEG_5470|M.smegmatis_MC2_155 MRSVEEQQARVAAAAVAPRPVRVAIAESQGLMCAEEVVTERPMPGFDQAA
TH_0939|M.thermoresistible__bu ---------------VAPRPVRVAIAEAQGLMCAEEVVTERPLPGFDQAA
MAB_1087|M.abscessus_ATCC_1997 MRSVEEQQAKVTAAAVAPRPVRVAIAEAQGLLCAEEVVTARPLPGFDQAA
*.***:******:***:*****:* **:*******
MUL_4692|M.ulcerans_Agy99 IDGYAVRSVDVMGVGQDL------ASGAAEFFVDDGSAISRD-AVTLPVM
MMAR_4520|M.marinum_M IDGYAVRSVDVVGVGQDL------ASGAAEFFVDDGSATSRD-AVTLPVM
Mb1021|M.bovis_AF2122/97 IDGYAVRSVDVAGVG---------DTGGVQVFADHGDLDGRD-VLTLPVM
Rv0994|M.tuberculosis_H37Rv IDGYAVRSVDVAGVG---------DTGGVQVFADHGDLDGRD-VLTLPVM
MLBr_00183|M.leprae_Br4923 IDGYAVRSVDVSGIGES--------DGGESGSSD---EDGRY-VLTLPVM
MAV_1103|M.avium_104 IDGYAVRSVDVLGVGEVG------AEGLPAPLDDS-VDDARD-GLVLPVM
Mflv_1898|M.gilvum_PYR-GCK IDGYAVRSVDVLGIGGP-------ADGQDDAYGDRDESRPR--EISLPVM
Mvan_4832|M.vanbaalenii_PYR-1 IDGYAVRSVDVLGIGGSD------EDAGLDGESDRDESRPR--EISLPVM
MSMEG_5470|M.smegmatis_MC2_155 IDGYAVRSVDVLGVGSDS------EDGG---------------EISLPVM
TH_0939|M.thermoresistible__bu IDGYAVRSVDVLGVGGG-------PDGEEG---------PDR-QVSLPVM
MAB_1087|M.abscessus_ATCC_1997 IDGYAVRSVDVQAAGGVVRVISPGEGGSPDDEDDIEESAGEIGTVELPVV
*********** . * . : ***:
MUL_4692|M.ulcerans_Agy99 GTIEAGARTPTRLQPKQVVRVQTGAPLPTLADAVLPLRWTDGGMNRVRVL
MMAR_4520|M.marinum_M GTIEAGARTPTRLQPKQAVRVQTGAPLPTLADAVLPLRWTDGGMNRVRVL
Mb1021|M.bovis_AF2122/97 GTIEAGARTLSRLQPRQAVRVQTGAPLPTLADAVLPLRWTDGGMSRVRVL
Rv0994|M.tuberculosis_H37Rv GTIEAGARTLSRLQPRQAVRVQTGAPLPTLADAVLPLRWTDGGMSRVRVL
MLBr_00183|M.leprae_Br4923 GTIEAGARTPSRLLPHQAVRVQTGAPLPVLADAVLPVRWTDGGMSRVRIL
MAV_1103|M.avium_104 GTVEAGSRTPSRLQPRQAVRVQTGAPLPTLADAVLPLGWTDGGTQRVRIY
Mflv_1898|M.gilvum_PYR-GCK GLIEAGARTPSRLQPRQAARVQTGAPMPTLADAVLPLRWTDGGDARVRVL
Mvan_4832|M.vanbaalenii_PYR-1 GLIEAGARTPSRLQPRQAARVQTGAPMPTLADAVLPLRWTDGGDSRVTVL
MSMEG_5470|M.smegmatis_MC2_155 GVIEAGARTPSRLQPRQAARVQTGAPMPTLADAVLPLRWTDGGENRVRVL
TH_0939|M.thermoresistible__bu ATIEAGSRTPTRLQPKQAARIQTGAPMPTLADAVLPLRWTDGGEKRVRVL
MAB_1087|M.abscessus_ATCC_1997 GTVRVGERTPTRLQPRQAVRVQTGAPMPTLADAVLPLRWSEGGESRVKVL
. :..* ** :** *:*..*:*****:*.*******: *::** ** :
MUL_4692|M.ulcerans_Agy99 RGAPSGAYVRHAGDDVQPGDVAVRSGTIIGAAQVGLLAAVGRERVLVHPR
MMAR_4520|M.marinum_M RGAPSGAYVRHAGDDVQPGDVAVRSGTIIGAAQVGLLAAVGRERVLVHPR
Mb1021|M.bovis_AF2122/97 RGAPSGAYVRRAGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPR
Rv0994|M.tuberculosis_H37Rv RGAPSGAYVRRAGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPR
MLBr_00183|M.leprae_Br4923 RGAPSGAYVRRVGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPR
MAV_1103|M.avium_104 RGAPSGAYVRRAGDDVQPGDVAVRAGAVIGAAQVGLLAAVGRERVLVHPR
Mflv_1898|M.gilvum_PYR-GCK RGVRSGAYVRRTGDDVQPGDVAVRAGAIIGPAQVGLLAAVGRERVLVHPR
Mvan_4832|M.vanbaalenii_PYR-1 RGVRSGAYVRRTGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRERVLVHPR
MSMEG_5470|M.smegmatis_MC2_155 RGVRSGAYVRRTGDDVQPGDVAVRAGTIIGPAQVGLLAAVGRDKVLVHPR
TH_0939|M.thermoresistible__bu RGVRSGAYVRRTGDDVQPGDVAVRAGTIIGPAQVGLLAAVGRERVLVHPR
MAB_1087|M.abscessus_ATCC_1997 RAVRSGDYVRRTGDDVQPGDVAVRAGTIIGAAQVGLLAAVGRDRVLVHPR
*.. ** ***:.************:*::**.***********::******
MUL_4692|M.ulcerans_Agy99 PRLSVMAVGGELVDISRTPGNGQVYDVNSYALAAAGRDAGAEVNRVGIVS
MMAR_4520|M.marinum_M PRLSVMAVGGELVDISRTPGNGQVYDVNSYALAAAGRDAGAEVNRVGIVS
Mb1021|M.bovis_AF2122/97 PRLSVMAVGGELVDISRTPGNGQVYDVNSYALAAAGRDAGAEVNRVGIVS
Rv0994|M.tuberculosis_H37Rv PRLSVMAVGGELVDISRTPGNGQVYDVNSYALAAAGRDACAEVNRVGIVS
MLBr_00183|M.leprae_Br4923 PRLSIMAVGGELVDISRTPGNGQVYDVNSYALTAAGRDAGAEVNRIGIVS
MAV_1103|M.avium_104 PRVTIMALGGELVDISRTPGNGQVYDVNSYALAAAARDAGAEVNRIGIVG
Mflv_1898|M.gilvum_PYR-GCK PRLSVMCVGGELVDISRTPGNGQVYDVNSYALAAAGRDAGAEVNRVGIVP
Mvan_4832|M.vanbaalenii_PYR-1 PRLSVMCVGGELVDISRTPGNGQVYDVNSYALAAAGRDAGAEVNRVGIVS
MSMEG_5470|M.smegmatis_MC2_155 PRLSVMCVGGELVDVSRTPGTGQVYDVNSYALAAAGRDAGAEVNRVGIIS
TH_0939|M.thermoresistible__bu PRLSVMSVGGELVDISRTPGNGQVYDVNSYALAAAGRDAGAEVNRVGILD
MAB_1087|M.abscessus_ATCC_1997 PRLSVISVGGELVDVDRTPGNGQVYDVNSYALAAAARDAGADVNRVGIVS
**::::.:******:.****.***********:**.*** *:***:**:
MUL_4692|M.ulcerans_Agy99 NDPNQLGEIVEGQINRAEVVVIAGGVGGAAAEAVRSVLSELGDMEVVRIA
MMAR_4520|M.marinum_M SDPKQLGEIVEGQINRAELVVIAGGVGGAAAEAVRSVLSELGDMEVVRIA
Mb1021|M.bovis_AF2122/97 NDPTELGEIVEGQLNRAEVVVIAGGVGGAAAEAVRSVLSELGEMEVVRVA
Rv0994|M.tuberculosis_H37Rv NDPTELGEIVEGQLNRAEVVVIAGGVGGAAAEAVRSVLSELGEMEVVRVA
MLBr_00183|M.leprae_Br4923 NNLKEFGEVVEGQISRAEVVVIAGGVGGAAAEAVRAVLSEIGEMEVVRVA
MAV_1103|M.avium_104 GGPRELRDIVEGQINRAEVIVIAGAVGGAAAEAVRQVLSELGEIEVVRVA
Mflv_1898|M.gilvum_PYR-GCK TDPAQLREVVEGQLSRAEIVVISGAVGGAAAEGVRTVLSQLGDMEVARIA
Mvan_4832|M.vanbaalenii_PYR-1 TDPKQLREVVEGQLSRAEVVVIAGAVGGAAAEAVRSVLAGLGDMEVARIA
MSMEG_5470|M.smegmatis_MC2_155 TDPRELRETVEGQVNRNEIVVIAGAVGGAAAESVRTVLSELGDMEVARIA
TH_0939|M.thermoresistible__bu PDPKELREVIEGQVNRSEVVVIAGGVGGAATEPVRRVLSELGEMEVTRIA
MAB_1087|M.abscessus_ATCC_1997 AEPAAFREVVEGQLNRAEVVVISGAVGGAAAEGIREALSALGDMEVGRIA
: : :***:.* *::**:*.*****:* :* .*: :*::** *:*
MUL_4692|M.ulcerans_Agy99 MHPGSVQGFGQLGRDRVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRQP
MMAR_4520|M.marinum_M MHPGSVQGFGQLGRDRVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRQP
Mb1021|M.bovis_AF2122/97 MHPGSVQGFGQLGRDGVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRHP
Rv0994|M.tuberculosis_H37Rv MHPGSVQGFGQLGRDGVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRHP
MLBr_00183|M.leprae_Br4923 MHPGSVQGFGQLGREGVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRQP
MAV_1103|M.avium_104 MHPGSIQGFGQLGREGVPTFLLPANPVSALVVFEVMVRPLIRLSLGKRQP
Mflv_1898|M.gilvum_PYR-GCK MHPGSVQGFGQLGPEGVPVFLLPANPVSALVVFEVMVRPLIRLSLGKRQA
Mvan_4832|M.vanbaalenii_PYR-1 MHPGSVQGFGQLGPDGVPVFLLPANPVSALVVFEVMVRPLIRLSLGKRQA
MSMEG_5470|M.smegmatis_MC2_155 MHPGSVQGFGQLGRDRVPVFLLPANPVSALVVFEIMVRPLIRLSLGKRQP
TH_0939|M.thermoresistible__bu MHPGSVQGFGQLGRDGVPVFLLPANPVSALVVFEVMVRPLIRMALGRRHP
MAB_1087|M.abscessus_ATCC_1997 MHPGSVQGFGQLGRDAVPTFLLPANPVGALVVFEVMVRPLIRLALGRRQS
*****:******* : **.********.******:*******::**:*:.
MUL_4692|M.ulcerans_Agy99 MRRIVQARTLSPITSVAGRKGYLRGQLMRDQESGEYLVQALGGAPGASSH
MMAR_4520|M.marinum_M MRRIVQARTLSPITSVAGRKGYLRGQLMRDQESGEYLVQALGGAPGASSH
Mb1021|M.bovis_AF2122/97 MRRIVSARTLSPITSVAGRKGYLRGQLMRDQDSGEYLVQALGGAPGASSH
Rv0994|M.tuberculosis_H37Rv MRRIVSARTLSPITSVAGRKGYLRGQLMRDQDSGEYLVQALGGAPGASSH
MLBr_00183|M.leprae_Br4923 MRRIVQARTLSPITSVAGRKGYLRGQLMRDQDTGEYLVQALGGALGASSH
MAV_1103|M.avium_104 MRRIVQARTLSPITSVAGRKGYLRGQLMRDQDSGEYLVQALGGAPGASSH
Mflv_1898|M.gilvum_PYR-GCK MRRIVPARALSPISSVAGRKGYLRGQLMRDQDTGEYLVQALGGAPGASSH
Mvan_4832|M.vanbaalenii_PYR-1 TRRIVPARALSPISSVAGRKGYLRGQLMRDQDTGEYLVQALGGAPGASSH
MSMEG_5470|M.smegmatis_MC2_155 MRRIVQARTLSPITSMPGRKGYLRGQLMRDQDTGEYLVQALGGAPGASTH
TH_0939|M.thermoresistible__bu MRRIVKARTLSPIVSVPGRKGFLRGQLMRDHETGEYLVQTLGGASGASSH
MAB_1087|M.abscessus_ATCC_1997 QRRIIQARTVSPITSIAGRKGFLRGQLMRDQDNGEYLVQILG-APGASSH
***: **::*** *:.****:********::.****** ** * ***:*
MUL_4692|M.ulcerans_Agy99 LLATLAEANCLVVVPTGAEQIRTGEIVDVAFLAQHG
MMAR_4520|M.marinum_M LLATLAEANCLVVVPTGAEQIRTGEIVDVAFLAQHG
Mb1021|M.bovis_AF2122/97 LLATLAEANCLVVVPTGAEQIRTGEIVDVAFLAQHG
Rv0994|M.tuberculosis_H37Rv LLATLAEANCLVVVPTGAEQIRTGEIVDVAFLAQHG
MLBr_00183|M.leprae_Br4923 LLATLAEANCLVVIPSGAEQIRTGEVVDVAFLAQRG
MAV_1103|M.avium_104 LLATLAEANCLVVVPSGAEQIRTGEIVDVAFLAQRG
Mflv_1898|M.gilvum_PYR-GCK LLATLAEANCLVIVPSEAEQIRTGEVVDVAFLAQRG
Mvan_4832|M.vanbaalenii_PYR-1 LLATLAEANCLVIVPSEAEQIRTGEIVDVAFLAQRG
MSMEG_5470|M.smegmatis_MC2_155 LLATLAEANCLVIVPADVEEVRTGETVDVAFLAQRG
TH_0939|M.thermoresistible__bu LLATLAEANCLVIVPAETEEVRTGEIVDVAFLAQRG
MAB_1087|M.abscessus_ATCC_1997 LLATLAEANCLVIVPAEVEQVRTGEIVEVAFLAQRG
************::*: .*::**** *:******:*