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PASTDPLTQNRNAAETMSGSRPFTDLTTAHDLGDGAYSATTDPIWTIGPKVHGGCMMAVCAAAAHRTIGD AVDLAPVALSANYISAPNPGEVQLTTKVRRRGRQVCLVDVELSQDSRTAVTCSVTLGSVDTKPPRHSAPL PVSQMPVQPPADAIPVSAEHPLAQILHVSQGCELAMDSATTGFLVGQRGAPIGRMWVRPFASDEADPAAA TLFAIMAGDIAPRVTVNCGIFGWTPTVQLTTYLRRRPAPGWMRVMASSTVIGDSWFEQDHVILDATGQVV VQSRQLAMLPEAAGASRRTAVDG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4450 | - | - | 100% (304) | hypothetical protein MUL_4450 |
| M. ulcerans Agy99 | MUL_4569 | - | 2e-55 | 43.68% (261) | hypothetical protein MUL_4569 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0510 | - | 5e-52 | 41.20% (267) | hypothetical protein Mb0510 |
| M. gilvum PYR-GCK | Mflv_0076 | - | 3e-61 | 42.91% (275) | hypothetical protein Mflv_0076 |
| M. tuberculosis H37Rv | Rv0499 | - | 6e-52 | 41.20% (267) | hypothetical protein Rv0499 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4010c | - | 5e-59 | 41.34% (283) | hypothetical protein MAB_4010c |
| M. marinum M | MMAR_4601 | - | 1e-163 | 97.91% (287) | hypothetical protein MMAR_4601 |
| M. avium 104 | MAV_4653 | - | 4e-59 | 41.84% (282) | hypothetical protein MAV_4653 |
| M. smegmatis MC2 155 | MSMEG_0942 | - | 4e-65 | 45.94% (283) | hypothetical protein MSMEG_0942 |
| M. thermoresistible (build 8) | TH_0956 | - | 3e-25 | 51.55% (97) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_0836 | - | 7e-59 | 40.89% (291) | hypothetical protein Mvan_0836 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0510|M.bovis_AF2122/97 -------------------MNALFTTAMALRPLDSDPGNPACRVFEGELN
Rv0499|M.tuberculosis_H37Rv -------------------MNALFTTAMALRPLDSDPGNPACRVFEGELN
MAV_4653|M.avium_104 -------------------MNALFTTAMTLREAGSG-------VYDGELD
Mflv_0076|M.gilvum_PYR-GCK -----------------MTSSTLFTDAMALTPAGDG-------VYHGVLN
Mvan_0836|M.vanbaalenii_PYR-1 ----------------MMAGSTLFTDAMALTPAGDG-------VYHGVLN
MSMEG_0942|M.smegmatis_MC2_155 -----------------MSASTLFTDAMALTPAGDG-------IYDGALD
TH_0956|M.thermoresistible__bu --------------------------------------------------
MAB_4010c|M.abscessus_ATCC_199 ------------------MVDAPFAQAMSLTPAGEG-------LFDAHLN
MUL_4450|M.ulcerans_Agy99 MPASTDPLTQNRNAAETMSGSRPFTDLTTAHDLGDG-------AYSATTD
MMAR_4601|M.marinum_M -----------------MSSSRPFTDLTTAHDLGDG-------AYSATID
Mb0510|M.bovis_AF2122/97 EHWTIGPKVHGGAMVALCANAARTAYGA-----AGQQPMRQPVAVSASFL
Rv0499|M.tuberculosis_H37Rv EHWTIGPKVHGGAMVALCANAARTAYGA-----AGQQPMRQPVAVSASFL
MAV_4653|M.avium_104 KRWTIGPKVHGGAMLALCANAARTAC-A-----GGPESAQQPVAVSASFL
Mflv_0076|M.gilvum_PYR-GCK EHWTIGPKVHGGAMLALCANAARSEFGE-----DGVEP----IAVSGSFL
Mvan_0836|M.vanbaalenii_PYR-1 EHWTIGPKVHGGAMLALCANAARTEFDE-----PGVEP----IAVSGSFL
MSMEG_0942|M.smegmatis_MC2_155 EHWTIGPKVHGGAMLALCANAAQTQIG------GELQP----IAVSGNFL
TH_0956|M.thermoresistible__bu --------------------------------------------------
MAB_4010c|M.abscessus_ATCC_199 DTWTIGPKLHGGVMLALLAGAARESLTEGLRTSGSSAGQREPIAVSASYL
MUL_4450|M.ulcerans_Agy99 PIWTIGPKVHGGCMMAVCAAAAHRTIGD--------AVDLAPVALSANYI
MMAR_4601|M.marinum_M PIWTIGPKVHSGCMMTVCAAAAHRTIGD--------AVDLAPVALSANYI
Mb0510|M.bovis_AF2122/97 WAPDPGTMRLVTSIRKRGRRISVADVELTQGG-----------RTAVHAV
Rv0499|M.tuberculosis_H37Rv WAPDPGTMRLVTSIRKRGRRISVADVELTQGG-----------RTAVHAV
MAV_4653|M.avium_104 WAPDPGPMRLVTSIRKRGRRISVVDVELTQGE-----------RTAVHAV
Mflv_0076|M.gilvum_PYR-GCK WAPDPGAMQVVTTVRKRGRRVSLLDVELQQGD-----------RVALRAA
Mvan_0836|M.vanbaalenii_PYR-1 WAPDPGPMEVVTTVRKRGRRVSLIDVELRQGVRTRDERSRVEQRVALRAA
MSMEG_0942|M.smegmatis_MC2_155 WAPDPGPMRLVTTVCKRGRRISVVDVELNQGA-----------RTAVRAS
TH_0956|M.thermoresistible__bu --------------------------------------------------
MAB_4010c|M.abscessus_ATCC_199 FAPSPGDMQVRTSVRKHGKQISLVDAELIQGD-----------RTAVHAV
MUL_4450|M.ulcerans_Agy99 SAPNPGEVQLTTKVRRRGRQVCLVDVELSQDS-----------RTAVTCS
MMAR_4601|M.marinum_M SAPNPGEVQLTTKVRRRGRQVCLVDVELSQDS-----------RTAVTCS
Mb0510|M.bovis_AF2122/97 VTLGEPEHFLPGVDGSGGASGTAPLLSAN-PVVELMAPEPPEGVVPIGPG
Rv0499|M.tuberculosis_H37Rv VTLGEPEHFLPGVDGSGGASGTAPLLSAN-PVVELMAPEPPEGVVPIGPG
MAV_4653|M.avium_104 VNLGEPEHFP--ADGS--AASAKPLLSAN-PVPALMPPEPPDDIEPIGPG
Mflv_0076|M.gilvum_PYR-GCK ITMGTPEHHVP------------PLLSVN-PVVPLMTPEPPPGLEPIGPG
Mvan_0836|M.vanbaalenii_PYR-1 ITMGTPEHHVP------------PLLSVN-PVIPLMTPEPPPGLEPIGPG
MSMEG_0942|M.smegmatis_MC2_155 VTLGEPEHHVA------------PLLSFN-PVSPLMAPEPPPEIAPIGPG
TH_0956|M.thermoresistible__bu --------------------------------------------------
MAB_4010c|M.abscessus_ATCC_199 VTLGTPEQHVG------------PLLTALPPALTQLPAEPPPGVAPIAEG
MUL_4450|M.ulcerans_Agy99 VTLGSVDTKP-------------PRHSAP-LPVSQMPVQPPADAIPVSAE
MMAR_4601|M.marinum_M VTLGSVDTKP-------------PRHSEP-LPVSQMPVQPPADAIPVSAE
Mb0510|M.bovis_AF2122/97 HQLAGLVHLGEGCDVRPVLSTLRSAT-DGRPPVIQLWARP-----RGVAP
Rv0499|M.tuberculosis_H37Rv HQLAGLVHLGEGCDVRPVLSTLRSAT-DGRPPVIQLWARP-----RGVAP
MAV_4653|M.avium_104 HPLAGLVHLGEGCDVRPVLSTMQPSA-DGRPPVIQMWARP-----RGVAP
Mflv_0076|M.gilvum_PYR-GCK HSMADIVHLAHGCDIRPSLTTFDPRQ-DGGMPVIEYWVRP-----KGVAP
Mvan_0836|M.vanbaalenii_PYR-1 HSMADIVHLAHGCDIRPSLTSFSRRA-DGGMPVIEYWVRP-----KGVAP
MSMEG_0942|M.smegmatis_MC2_155 HPMEHIVHLAHGCDIRPALHTLGARE-GGGPPVFEYWVRP-----KGVAP
TH_0956|M.thermoresistible__bu --------------------------------VVEMWVRP-----RDAAP
MAB_4010c|M.abscessus_ATCC_199 HPMGEIFHLFGGLDVRPSLRSMSDLS-ERGKPEIVLWARP-----RDMAP
MUL_4450|M.ulcerans_Agy99 HPLAQILHVSQGCELAMDSATTGFLVGQRGAPIGRMWVRPFASDEADPAA
MMAR_4601|M.marinum_M HPLAQILHVSQGCELAMDSATTGFLVGQRGAPISRMWVRPFASDEADPAA
*.** . *.
Mb0510|M.bovis_AF2122/97 DALFALLCGDLSAPVTFAVDRTGWAPTVALTAYLRALPADGWLRVLCTCV
Rv0499|M.tuberculosis_H37Rv DALFALLCGDLSAPVTFAVDRTGWAPTVALTAYLRALPADGWLRVLCTCV
MAV_4653|M.avium_104 DALFALMCGDLSAPVTFAVDRTGWAPTIQLTAFLRGLPADGWLRIIATCT
Mflv_0076|M.gilvum_PYR-GCK DLLFALLCGDVSAPVTFGVNRFGWAPTVQLTAYLRALPADGWLRVMCTAT
Mvan_0836|M.vanbaalenii_PYR-1 DVLFALLCGDVSAPVTFGVNRFGWAPTVQLTAFLRALPADGWLRVMCTAT
MSMEG_0942|M.smegmatis_MC2_155 DVLFALLCGDVSAPVTFAVERTGWAPTVQLTAYLRGLPADGWLRVMCTTV
TH_0956|M.thermoresistible__bu DVLFALMCGDVSAPVTYAVQRFGWAPTVQLTAYLRGLPADGWLRVICTTM
MAB_4010c|M.abscessus_ATCC_199 DGLFALVCGDISVPVTFPLGRFGWAPTVQLTTYLRTLPADGWLRVLCSTN
MUL_4450|M.ulcerans_Agy99 ATLFAIMAGDIAPRVTVNCGIFGWTPTVQLTTYLRRRPAPGWMRVMASST
MMAR_4601|M.marinum_M ATLFAIMAGDIAPRVTVNCGIFGWTPTVQLTTYLRRRPAPGWMRVMASST
***::.**:: ** **:**: **::** ** **:*::.:
Mb0510|M.bovis_AF2122/97 EIGQDWFDEDHIVVDRLGRIVVQTRQLAMVPAQ-----------
Rv0499|M.tuberculosis_H37Rv EIGQDWFDEDHIVVDRLGRIVVQTRQLAMVPAQ-----------
MAV_4653|M.avium_104 EIGHDWFDEDHTVVDSLGRLVVQARQLALVPAAP----------
Mflv_0076|M.gilvum_PYR-GCK QIGEDWFDEDHIVVDCEGRIIVQTRQLAMVPSR-----------
Mvan_0836|M.vanbaalenii_PYR-1 QIGQDWFDEDHIVVDCEGRIIVQTRQLALVPTG-----------
MSMEG_0942|M.smegmatis_MC2_155 QIGEDWFDEDHTVVDCEGRIIVQSRQLAMVPTAQG---------
TH_0956|M.thermoresistible__bu QIGQDWFDEDHVVVDHAGRIIVQTRQLAMVPQR-----------
MAB_4010c|M.abscessus_ATCC_199 QIGQHWFDSEHTVIDSEGALVVQSRQLAMVPVN-----------
MUL_4450|M.ulcerans_Agy99 VIGDSWFEQDHVILDATGQVVVQSRQLAMLPEAAGASRRTAVDG
MMAR_4601|M.marinum_M VIGDSWFEQDHVILDATGQVVVQSRQLAMLPEAAGASRRTAVDG
**. **:.:* ::* * ::**:****::*