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M. tuberculosis H37Rv Rv0499 (-)

annotation: hypothetical protein Rv0499
coordinates: 589183 - 590058
length: 291

MNALFTTAMALRPLDSDPGNPACRVFEGELNEHWTIGPKVHGGAMVALCANAARTAYGAAGQQPMRQPVA
VSASFLWAPDPGTMRLVTSIRKRGRRISVADVELTQGGRTAVHAVVTLGEPEHFLPGVDGSGGASGTAPL
LSANPVVELMAPEPPEGVVPIGPGHQLAGLVHLGEGCDVRPVLSTLRSATDGRPPVIQLWARPRGVAPDA
LFALLCGDLSAPVTFAVDRTGWAPTVALTAYLRALPADGWLRVLCTCVEIGQDWFDEDHIVVDRLGRIVV
QTRQLAMVPAQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0499--100% (291)hypothetical protein Rv0499

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0510-1e-171100.00% (291) hypothetical protein Mb0510
M. gilvum PYR-GCKMflv_0076-1e-10663.79% (290) hypothetical protein Mflv_0076
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4010c-2e-7952.35% (298) hypothetical protein MAB_4010c
M. marinum MMMAR_0825-1e-11972.45% (294) hypothetical protein MMAR_0825
M. avium 104MAV_4653-1e-12575.52% (290) hypothetical protein MAV_4653
M. smegmatis MC2 155MSMEG_0942-1e-10565.28% (288) hypothetical protein MSMEG_0942
M. thermoresistible (build 8)TH_0956-8e-4276.60% (94) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_4569-1e-12073.13% (294) hypothetical protein MUL_4569
M. vanbaalenii PYR-1Mvan_0836-1e-10261.20% (299) hypothetical protein Mvan_0836

CLUSTAL 2.0.9 multiple sequence alignment


Rv0499|M.tuberculosis_H37Rv         ---MNALFTTAMALRPLDSDPGNPACRVFEGELNEHWTIGPKVHGGAMVA
Mb0510|M.bovis_AF2122/97            ---MNALFTTAMALRPLDSDPGNPACRVFEGELNEHWTIGPKVHGGAMVA
MMAR_0825|M.marinum_M               ---MNALFTTAMALREVEAPAGG-QCRIFDGELDENWTIGPKVHGGVMLA
MUL_4569|M.ulcerans_Agy99           ---MNALFTTAMALREVEAPAGG-QCRIFDGELDENWTIGPKVHGGVMLA
MAV_4653|M.avium_104                ---MNALFTTAMTLREAGS--G-----VYDGELDKRWTIGPKVHGGAMLA
Mflv_0076|M.gilvum_PYR-GCK          -MTSSTLFTDAMALTPAGDG-------VYHGVLNEHWTIGPKVHGGAMLA
Mvan_0836|M.vanbaalenii_PYR-1       MMAGSTLFTDAMALTPAGDG-------VYHGVLNEHWTIGPKVHGGAMLA
MSMEG_0942|M.smegmatis_MC2_155      -MSASTLFTDAMALTPAGDG-------IYDGALDEHWTIGPKVHGGAMLA
TH_0956|M.thermoresistible__bu      --------------------------------------------------
MAB_4010c|M.abscessus_ATCC_199      --MVDAPFAQAMSLTPAGEG-------LFDAHLNDTWTIGPKLHGGVMLA
                                                                                      

Rv0499|M.tuberculosis_H37Rv         LCANAARTAYGAAG-----QQPMRQPVAVSASFLWAPDPGTMRLVTSIRK
Mb0510|M.bovis_AF2122/97            LCANAARTAYGAAG-----QQPMRQPVAVSASFLWAPDPGTMRLVTSIRK
MMAR_0825|M.marinum_M               LCAKAARAAHGG---------DALQPVAVSTNFLWAPDPGPMRLVTSIRK
MUL_4569|M.ulcerans_Agy99           LCAKAARGAHGG---------DALQPVAVSTNFLWAPDPGPMRLVTSIRK
MAV_4653|M.avium_104                LCANAARTACAGG------PESAQQPVAVSASFLWAPDPGPMRLVTSIRK
Mflv_0076|M.gilvum_PYR-GCK          LCANAARSEFGE---------DGVEPIAVSGSFLWAPDPGAMQVVTTVRK
Mvan_0836|M.vanbaalenii_PYR-1       LCANAARTEFDE---------PGVEPIAVSGSFLWAPDPGPMEVVTTVRK
MSMEG_0942|M.smegmatis_MC2_155      LCANAAQTQIG----------GELQPIAVSGNFLWAPDPGPMRLVTTVCK
TH_0956|M.thermoresistible__bu      --------------------------------------------------
MAB_4010c|M.abscessus_ATCC_199      LLAGAARESLTEGLRTSGSSAGQREPIAVSASYLFAPSPGDMQVRTSVRK
                                                                                      

Rv0499|M.tuberculosis_H37Rv         RGRRISVADVELTQGG-----------RTAVHAVVTLGEPEHFLPGVDGS
Mb0510|M.bovis_AF2122/97            RGRRISVADVELTQGG-----------RTAVHAVVTLGEPEHFLPGVDGS
MMAR_0825|M.marinum_M               RGRRISVVDVELMQGE-----------RTAVHAVVTLGEPEHYESG----
MUL_4569|M.ulcerans_Agy99           RGRRISVVDVELMQGK-----------RTAVHAVVTLGEPEHYESG----
MAV_4653|M.avium_104                RGRRISVVDVELTQGE-----------RTAVHAVVNLGEPEHFPADGS--
Mflv_0076|M.gilvum_PYR-GCK          RGRRVSLLDVELQQGD-----------RVALRAAITMGTPEH--------
Mvan_0836|M.vanbaalenii_PYR-1       RGRRVSLIDVELRQGVRTRDERSRVEQRVALRAAITMGTPEH--------
MSMEG_0942|M.smegmatis_MC2_155      RGRRISVVDVELNQGA-----------RTAVRASVTLGEPEH--------
TH_0956|M.thermoresistible__bu      --------------------------------------------------
MAB_4010c|M.abscessus_ATCC_199      HGKQISLVDAELIQGD-----------RTAVHAVVTLGTPEQ--------
                                                                                      

Rv0499|M.tuberculosis_H37Rv         GGASGTAPLLSAN-PVVELMAPEPPEGVVPIGPGHQLAGLVHLGEGCDVR
Mb0510|M.bovis_AF2122/97            GGASGTAPLLSAN-PVVELMAPEPPEGVVPIGPGHQLAGLVHLGEGCDVR
MMAR_0825|M.marinum_M               ----PATPLLSAN-PVLEMMAPEPPDDVTPIGPSHALAGLAHLGAGCDVR
MUL_4569|M.ulcerans_Agy99           ----PAAPLLSAN-PVLEMMAPEPPDDVTPIGPGHALAGLAHLGAGCDVR
MAV_4653|M.avium_104                --AASAKPLLSAN-PVPALMPPEPPDDIEPIGPGHPLAGLVHLGEGCDVR
Mflv_0076|M.gilvum_PYR-GCK          ----HVPPLLSVN-PVVPLMTPEPPPGLEPIGPGHSMADIVHLAHGCDIR
Mvan_0836|M.vanbaalenii_PYR-1       ----HVPPLLSVN-PVIPLMTPEPPPGLEPIGPGHSMADIVHLAHGCDIR
MSMEG_0942|M.smegmatis_MC2_155      ----HVAPLLSFN-PVSPLMAPEPPPEIAPIGPGHPMEHIVHLAHGCDIR
TH_0956|M.thermoresistible__bu      --------------------------------------------------
MAB_4010c|M.abscessus_ATCC_199      ----HVGPLLTALPPALTQLPAEPPPGVAPIAEGHPMGEIFHLFGGLDVR
                                                                                      

Rv0499|M.tuberculosis_H37Rv         PVLSTLRSATD---GRPPVIQLWARPRGVAPDALFALLCGDLSAPVTFAV
Mb0510|M.bovis_AF2122/97            PVLSTLRSATD---GRPPVIQLWARPRGVAPDALFALLCGDLSAPVTFAV
MMAR_0825|M.marinum_M               PLASTLQTPASGWGGRAPTFQMWARPRGVAPDALFALMCGDLSVPVTFAV
MUL_4569|M.ulcerans_Agy99           PLASTLQTPASGWGGRAPTFQMWARPRGVAPDALFALMCGDLSVPVTFAV
MAV_4653|M.avium_104                PVLSTMQPSAD---GRPPVIQMWARPRGVAPDALFALMCGDLSAPVTFAV
Mflv_0076|M.gilvum_PYR-GCK          PSLTTFDPRQD---GGMPVIEYWVRPKGVAPDLLFALLCGDVSAPVTFGV
Mvan_0836|M.vanbaalenii_PYR-1       PSLTSFSRRAD---GGMPVIEYWVRPKGVAPDVLFALLCGDVSAPVTFGV
MSMEG_0942|M.smegmatis_MC2_155      PALHTLGAREG---GGPPVFEYWVRPKGVAPDVLFALLCGDVSAPVTFAV
TH_0956|M.thermoresistible__bu      ------------------VVEMWVRPRDAAPDVLFALMCGDVSAPVTYAV
MAB_4010c|M.abscessus_ATCC_199      PSLRSMSDLSE---RGKPEIVLWARPRDMAPDGLFALVCGDISVPVTFPL
                                                       .  *.**:. *** ****:***:*.***: :

Rv0499|M.tuberculosis_H37Rv         DRTGWAPTVALTAYLRALPADGWLRVLCTCVEIGQDWFDEDHIVVDRLGR
Mb0510|M.bovis_AF2122/97            DRTGWAPTVALTAYLRALPADGWLRVLCTCVEIGQDWFDEDHIVVDRLGR
MMAR_0825|M.marinum_M               GRTGWAPTVQLTAILRALPTDGWLRIVATCVEIGQGWFDEDHIVVDQAGR
MUL_4569|M.ulcerans_Agy99           GRTGWAPTVQLTAILRALPTDGWLRIVATCVEIGQGWFDEDHIVVDQAGR
MAV_4653|M.avium_104                DRTGWAPTIQLTAFLRGLPADGWLRIIATCTEIGHDWFDEDHTVVDSLGR
Mflv_0076|M.gilvum_PYR-GCK          NRFGWAPTVQLTAYLRALPADGWLRVMCTATQIGEDWFDEDHIVVDCEGR
Mvan_0836|M.vanbaalenii_PYR-1       NRFGWAPTVQLTAFLRALPADGWLRVMCTATQIGQDWFDEDHIVVDCEGR
MSMEG_0942|M.smegmatis_MC2_155      ERTGWAPTVQLTAYLRGLPADGWLRVMCTTVQIGEDWFDEDHTVVDCEGR
TH_0956|M.thermoresistible__bu      QRFGWAPTVQLTAYLRGLPADGWLRVICTTMQIGQDWFDEDHVVVDHAGR
MAB_4010c|M.abscessus_ATCC_199      GRFGWAPTVQLTTYLRTLPADGWLRVLCSTNQIGQHWFDSEHTVIDSEGA
                                     * *****: **: ** **:*****::.:  :**. ***.:* *:*  * 

Rv0499|M.tuberculosis_H37Rv         IVVQTRQLAMVPAQ--
Mb0510|M.bovis_AF2122/97            IVVQTRQLAMVPAQ--
MMAR_0825|M.marinum_M               IVVQTRQLAMVPAR--
MUL_4569|M.ulcerans_Agy99           IVVQTRQLAMVPAR--
MAV_4653|M.avium_104                LVVQARQLALVPAAP-
Mflv_0076|M.gilvum_PYR-GCK          IIVQTRQLAMVPSR--
Mvan_0836|M.vanbaalenii_PYR-1       IIVQTRQLALVPTG--
MSMEG_0942|M.smegmatis_MC2_155      IIVQSRQLAMVPTAQG
TH_0956|M.thermoresistible__bu      IIVQTRQLAMVPQR--
MAB_4010c|M.abscessus_ATCC_199      LVVQSRQLAMVPVN--
                                    ::**:****:**