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MTATSEDSAAVPRFDGLRALFINTTLKRSPDLSHTEGLIARSSQIMREHCVEVDSFRAIDHNIATGVWPD MTEHGWEADEWPDLYQRVLRANILVLCGPIWLGDNSSVMKLVIERLYSCSGLLNENGQYAYYGRVGGCLF TGNEDGVKHCAMNVLYNLQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPQNDFTNRNTTFMTFNLMHL AQMLQRAGGVPAYGNQRTEWDAGCRPDFANPDYR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4444 | - | - | 100% (244) | hypothetical protein MUL_4444 |
| M. ulcerans Agy99 | MUL_1351 | wrbA | 1e-37 | 39.90% (203) | multimeric flavodoxin WrbA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0948c | mntH | 1e-110 | 84.72% (216) | putative manganese transport protein MntH |
| M. gilvum PYR-GCK | Mflv_1969 | - | 6e-22 | 33.33% (201) | hypothetical protein Mflv_1969 |
| M. tuberculosis H37Rv | Rv0925c | - | 1e-128 | 85.31% (245) | hypothetical protein Rv0925c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2520c | - | 3e-20 | 36.81% (163) | hypothetical protein MAB_2520c |
| M. marinum M | MMAR_4583 | - | 1e-146 | 98.77% (244) | hypothetical protein MMAR_4583 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1768 | - | 1e-18 | 31.88% (207) | hypothetical protein MSMEG_1768 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4745 | - | 2e-23 | 34.33% (201) | hypothetical protein Mvan_4745 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4444|M.ulcerans_Agy99 MTATSE-DSAAVPRFDGLRALFINTTLKRSPDLSHTEGLIARSSQIMREH
MMAR_4583|M.marinum_M MTATSD-DSAAVPRFDGLRALFINTTLKRSPDLSHTEGLIARSSQIMREH
Mb0948c|M.bovis_AF2122/97 MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREH
Rv0925c|M.tuberculosis_H37Rv MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREH
Mflv_1969|M.gilvum_PYR-GCK ----------MEHNQQSLRAVALICSLKPSPAESSSALMAEHVFENLRAH
Mvan_4745|M.vanbaalenii_PYR-1 ----------MAENAIPVRALGLICSLKPSPAPSSSALIAEHVFETLREQ
MSMEG_1768|M.smegmatis_MC2_155 ------------MTAPTLTALALVCSLKRSPAESSSDLMARHVCDDLGAA
MAB_2520c|M.abscessus_ATCC_199 ----------MTIVQEPLRALSLVCSLKRTGEHSSTEMLTNQLAEVLGHD
: *: : :** : * : : : :
MUL_4444|M.ulcerans_Agy99 CVEVDSFRAIDHNIATGVWPDMTEHGWEADEWPDLYQRVLRANILVLCGP
MMAR_4583|M.marinum_M GVEVDSFRAIDHNIATGVWPDMTEHGWEADEWPDLYQRVLRANILVLCGP
Mb0948c|M.bovis_AF2122/97 GVQVDTLRAVDHDIATGVWPDMTEHGWATDEWPALYRRVLDAHILVLCGP
Rv0925c|M.tuberculosis_H37Rv GVQVDTLRAVDHDIATGVWPDMTEHGWATDEWPALYRRVLDAHILVLCGP
Mflv_1969|M.gilvum_PYR-GCK GVDCEQVRCVDYDIAPGVEADMGGG----DQWPQIREKILAADILVLSSP
Mvan_4745|M.vanbaalenii_PYR-1 GAECEAVRCVDFNIAPGVEADMGDS----DQWPQIRQKVLAADILLISTP
MSMEG_1768|M.smegmatis_MC2_155 GVGTEILRCADYTIEPGVEADMGGD----DQWPRIREKILGADILVLSTP
MAB_2520c|M.abscessus_ATCC_199 GVHCESIRCVDYDIHPGVGQDMGNG----DQWPQLRDKVLGADILVLGTP
. : .*. *. * .** ** *:** : ::* *.**:: *
MUL_4444|M.ulcerans_Agy99 IWLGDNSSVMKLVIERLYSCSGLLNENGQYAYYGRVGGCLFTGNEDGVKH
MMAR_4583|M.marinum_M IWLGDNSSVMKLVIERLYSCSGLLNENGQYAYYGRVGGCLFTGNEDGVKH
Mb0948c|M.bovis_AF2122/97 IWLGDNSSVMKRVIERLYACSSLLNEDGQYAYYGRAGGCLITGNEDGVKH
Rv0925c|M.tuberculosis_H37Rv IWLGDNSSVMKRVIERLYACSSLLNEDGQYAYYGRAGGCLITGNEDGVKH
Mflv_1969|M.gilvum_PYR-GCK IWLGHPASVTQRVLERLDAELSNTDEQERPVMVGKVALVAVVGNEDGAHK
Mvan_4745|M.vanbaalenii_PYR-1 VWLGHPSSVTQRVLERLDAELSNTDDQGRPAMAGKVAIVSVVGNEDGAHK
MSMEG_1768|M.smegmatis_MC2_155 VWVGHPSSITQRVLERLDAELSNTDDAGRPVLAGKVVLVAVVGNEDGAHK
MAB_2520c|M.abscessus_ATCC_199 TWLGHMSSVAQRVLERLDAELSETDEEGRPILSGKVAVAAVVGNEDGAHK
*:*. :*: : *:*** : . :: : *:. ..*****.::
MUL_4444|M.ulcerans_Agy99 CAMNVLYNLQHLGYTIPPQADAGWIGEAGPG------PSYLDPGSGGPQN
MMAR_4583|M.marinum_M CAMNVLYSLQHLGYTIPPQADAGWIGEAGPG------PSYLDPGSGGPQN
Mb0948c|M.bovis_AF2122/97 CAMNVLYSLQHLGYTIPPQADAGWIGEAGPG------PSYLDPGSGGPEN
Rv0925c|M.tuberculosis_H37Rv CAMNVLYSLQHLGYTIPPQADAGWIGEAGPG------PSYLDPGSGGPEN
Mflv_1969|M.gilvum_PYR-GCK VVADLFQALNDVGYSIPAQGCTYWNGPAMES------GDYKDLDEVPEQV
Mvan_4745|M.vanbaalenii_PYR-1 VVADVFQGLNDVGYSIPAQGCTYWNGPAMES------TDYKDLDEVPEQV
MSMEG_1768|M.smegmatis_MC2_155 TVADVFQALNDMGYSIPAQGCTYWNGEAMQG------VDFKDLDTVPDPV
MAB_2520c|M.abscessus_ATCC_199 ITADLFQALNDIGFSVPARAAPIGMARPCTKRIIASWTACRRPWRRRRPP
. ::: *:.:*:::*.:. . . .
MUL_4444|M.ulcerans_Agy99 DFTNRNTTFMTFNLMHLAQMLQRAG-----------GVPAYG--------
MMAR_4583|M.marinum_M DFTNRNTTFMTFNLMHLAQMLQRAG-----------GVPAYG--------
Mb0948c|M.bovis_AF2122/97 DFTNRNTTFMTFNLMHIAQMLRAPAASRPTAINAPSGTPAAGRTSPTPTT
Rv0925c|M.tuberculosis_H37Rv DFTNRNTTFMTFNLMHIAQMLRVAG-----------GIPAYG--------
Mflv_1969|M.gilvum_PYR-GCK ASTTAAAARN---AAHLARALKQAQ------------YPSYQ--------
Mvan_4745|M.vanbaalenii_PYR-1 ASTTAAAARN---AVRLARVLKQAQ------------YPPY---------
MSMEG_1768|M.smegmatis_MC2_155 AGATAAAARN---AAHLAGLLSTGP------------YPRYE--------
MAB_2520c|M.abscessus_ATCC_199 RHTTPHILRNYCVNTAIPQLNRRNH------------ARRWNRPR-----
:. :.
MUL_4444|M.ulcerans_Agy99 -NQR----TEWDAG----------------------CRPDFANPDYR---
MMAR_4583|M.marinum_M -NQR----TEWDAG----------------------CRPDFANPDYR---
Mb0948c|M.bovis_AF2122/97 DSQRRSRVARWLVAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGP
Rv0925c|M.tuberculosis_H37Rv -NQR----TKWDAG----------------------CRPDFANPDYR---
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4444|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4583|M.marinum_M --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 AFVAAIAYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLG
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4444|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4583|M.marinum_M --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 LVTGRSLPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMF
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4444|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4583|M.marinum_M --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 NLPLPIGGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFF
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4444|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4583|M.marinum_M --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 VVTPPPNAVLGGLAPRFQGTESVLLAAAIMGATVMPHAVYLHSGLARDRH
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4444|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4583|M.marinum_M --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 GHPDPGPQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGRGDTAS
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4444|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4583|M.marinum_M --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 IEGAYHAVHDTLGATIAVLFAVGLLASGLASSSVGAYAGAMIMQGLLHWS
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4444|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4583|M.marinum_M --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 VPMLVRRLITLGPALAILTLGFDPTRTLVLSQVVLSFGIPFAVLPLVKLT
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_4444|M.ulcerans_Agy99 ----------------------------------------
MMAR_4583|M.marinum_M ----------------------------------------
Mb0948c|M.bovis_AF2122/97 GSPAVMGGDTNHRATTWVGWVVAVMVSLLNVMLIYLTVTG
Rv0925c|M.tuberculosis_H37Rv ----------------------------------------
Mflv_1969|M.gilvum_PYR-GCK ----------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 ----------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 ----------------------------------------
MAB_2520c|M.abscessus_ATCC_199 ----------------------------------------