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KKEGPLYALFLNCTLKKGPEVSNTEALCNLLIDRLKAHEPDIEAEIVRVVDYDVKPGVGNDEGDGDEWPL ILEKVKRANIIVPAMPIWMGVRSSVMQRVIERLDGTTRTVMCEKTGQFPLYGSVAGIVVTGNEDGSHDCV ANTFGNLLHFGATVPPNTDLYWVGDAGPGASYIEAGGELSPYVRRNAELTATNLLFAAKLLRENPYSVNI AQLNAQMMDRNKVKMAAMKLAIDYMRANMPD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1351 | wrbA | - | 100% (242) | multimeric flavodoxin WrbA |
| M. ulcerans Agy99 | MUL_4444 | - | 1e-37 | 39.90% (203) | hypothetical protein MUL_4444 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0948c | mntH | 7e-38 | 39.41% (203) | putative manganese transport protein MntH |
| M. gilvum PYR-GCK | Mflv_1969 | - | 1e-29 | 36.82% (201) | hypothetical protein Mflv_1969 |
| M. tuberculosis H37Rv | Rv0925c | - | 8e-38 | 39.41% (203) | hypothetical protein Rv0925c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2520c | - | 6e-28 | 45.70% (151) | hypothetical protein MAB_2520c |
| M. marinum M | MMAR_3278 | wrbA | 1e-139 | 98.35% (242) | multimeric flavodoxin WrbA |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1768 | - | 1e-28 | 36.82% (201) | hypothetical protein MSMEG_1768 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4745 | - | 3e-29 | 36.14% (202) | hypothetical protein Mvan_4745 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1351|M.ulcerans_Agy99 -----------MKKEGPLYALFLNCTLKKGPEVSNTEALCNLLIDRLKAH
MMAR_3278|M.marinum_M ---MASSIFHEMKKEGPLYALFLNCTLKKGPEVSNTEALCNLLIDRLKAH
Mflv_1969|M.gilvum_PYR-GCK ----------MEHNQQSLRAVALICSLKPSPAESSSALMAEHVFENLRAH
Mvan_4745|M.vanbaalenii_PYR-1 ----------MAENAIPVRALGLICSLKPSPAPSSSALIAEHVFETLREQ
MSMEG_1768|M.smegmatis_MC2_155 ------------MTAPTLTALALVCSLKRSPAESSSDLMARHVCDDLGAA
MAB_2520c|M.abscessus_ATCC_199 ----------MTIVQEPLRALSLVCSLKRTGEHSSTEMLTNQLAEVLGHD
Mb0948c|M.bovis_AF2122/97 MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREH
Rv0925c|M.tuberculosis_H37Rv MTTTSDQNAAAPPRFDGLRALFINATLKRSPELSHTDGLIERSSGIMREH
: *: : .:** * : : . :
MUL_1351|M.ulcerans_Agy99 EPDIEAEIVRVVDYDVKPGVGNDEGDG----DEWPLILEKVKRANIIVPA
MMAR_3278|M.marinum_M EPDIETEIVRVVDYDVKPGVGNDEGDG----DEWPLILEKVKRANIIVPA
Mflv_1969|M.gilvum_PYR-GCK G--VDCEQVRCVDYDIAPGVEADMGGG----DQWPQIREKILAADILVLS
Mvan_4745|M.vanbaalenii_PYR-1 G--AECEAVRCVDFNIAPGVEADMGDS----DQWPQIRQKVLAADILLIS
MSMEG_1768|M.smegmatis_MC2_155 G--VGTEILRCADYTIEPGVEADMGGD----DQWPRIREKILGADILVLS
MAB_2520c|M.abscessus_ATCC_199 G--VHCESIRCVDYDIHPGVGQDMGNG----DQWPQLRDKVLGADILVLG
Mb0948c|M.bovis_AF2122/97 G--VQVDTLRAVDHDIATGVWPDMTEHGWATDEWPALYRRVLDAHILVLC
Rv0925c|M.tuberculosis_H37Rv G--VQVDTLRAVDHDIATGVWPDMTEHGWATDEWPALYRRVLDAHILVLC
: :* .*. : .** * *:** : :: *.*::
MUL_1351|M.ulcerans_Agy99 MPIWMGVRSSVMQRVIERLDGTTRTVMCEKTGQFPLYGSVAGIVVTGNED
MMAR_3278|M.marinum_M MPIWMGVRSSVMQRVIERLDGTTKTVMCEKTGQFPLYGSVAGIVVTGNED
Mflv_1969|M.gilvum_PYR-GCK SPIWLGHPASVTQRVLERLD--AELSNTDEQERPVMVGKVALVAVVGNED
Mvan_4745|M.vanbaalenii_PYR-1 TPVWLGHPSSVTQRVLERLD--AELSNTDDQGRPAMAGKVAIVSVVGNED
MSMEG_1768|M.smegmatis_MC2_155 TPVWVGHPSSITQRVLERLD--AELSNTDDAGRPVLAGKVVLVAVVGNED
MAB_2520c|M.abscessus_ATCC_199 TPTWLGHMSSVAQRVLERLD--AELSETDEEGRPILSGKVAVAAVVGNED
Mb0948c|M.bovis_AF2122/97 GPIWLGDNSSVMKRVIERLY--ACSSLLNEDGQYAYYGRAGGCLITGNED
Rv0925c|M.tuberculosis_H37Rv GPIWLGDNSSVMKRVIERLY--ACSSLLNEDGQYAYYGRAGGCLITGNED
* *:* :*: :**:*** : :. : * . :.****
MUL_1351|M.ulcerans_Agy99 GSHDCVANTFGNLLHFGATVPPNTDLYWVGDAGPGASYIE--AGGELSPY
MMAR_3278|M.marinum_M GSHDCVANTFGNLLHFGATVPPNTDLYWVGDAGPGASYIE--AGGELSPY
Mflv_1969|M.gilvum_PYR-GCK GAHKVVADLFQALNDVGYSIPAQGCTYWNGPAMES--------GDYKDLD
Mvan_4745|M.vanbaalenii_PYR-1 GAHKVVADVFQGLNDVGYSIPAQGCTYWNGPAMES--------TDYKDLD
MSMEG_1768|M.smegmatis_MC2_155 GAHKTVADVFQALNDMGYSIPAQGCTYWNGEAMQG--------VDFKDLD
MAB_2520c|M.abscessus_ATCC_199 GAHKITADLFQALNDIGFSVPARAAPIGMARPCTKRIIAS--WTACRRPW
Mb0948c|M.bovis_AF2122/97 GVKHCAMNVLYSLQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPENDF
Rv0925c|M.tuberculosis_H37Rv GVKHCAMNVLYSLQHLGYTIPPQADAGWIGEAGPGPSYLDPGSGGPENDF
* :. . : : * ..* ::*.. . .
MUL_1351|M.ulcerans_Agy99 VRRNAELTATNLLFAAKLLRENPYSVNIAQLNAQMMDRNKVKMAAMKLAI
MMAR_3278|M.marinum_M VRRNAELTATNLLFAAKLLRENPYAVNIAQLNAQMMERNKVKMAAMKLAI
Mflv_1969|M.gilvum_PYR-GCK EVPEQVASTT-----AAAARN---AAHLARALKQAQYPS-----------
Mvan_4745|M.vanbaalenii_PYR-1 EVPEQVASTT-----AAAARN---AVRLARVLKQAQYPP-----------
MSMEG_1768|M.smegmatis_MC2_155 TVPDPVAGAT-----AAAARN---AAHLAGLLSTGPYPR-----------
MAB_2520c|M.abscessus_ATCC_199 RRRRPPRHTT-----PHILRNYCVNTAIPQLNRRNHARR-----------
Mb0948c|M.bovis_AF2122/97 TNRNTTFMTFNLMHIAQMLRAPAASRPTAINAPSGTPAAGRTSPTPTTDS
Rv0925c|M.tuberculosis_H37Rv TNRNTTFMTFNLMHIAQMLRVAG-----------GIPAYG---------N
: . *
MUL_1351|M.ulcerans_Agy99 DYMRANMPD-----------------------------------------
MMAR_3278|M.marinum_M DYMRANMPD-----------------------------------------
Mflv_1969|M.gilvum_PYR-GCK -YQ-----------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 -Y------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 -YE-----------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 -WNRPR--------------------------------------------
Mb0948c|M.bovis_AF2122/97 QRRSRVARWLVAGEFRLLSHLCSRGSKVGELAQDTRTSLKTSWYLLGPAF
Rv0925c|M.tuberculosis_H37Rv QR----TKWDAG----------------------CRPDFANPDYR-----
MUL_1351|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3278|M.marinum_M --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 VAAIAYVDPGNVAANVSSGAQFGYLLLWVIVAANVMAALVQYLSAKLGLV
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1351|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3278|M.marinum_M --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 TGRSLPEAIGKRMGRPARLAYWAQAEIVAMATDVAEVIGGAIALRIMFNL
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1351|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3278|M.marinum_M --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 PLPIGGIITGVVSLLLLTIQDRRGQRLFERVITALLLVIAIGFTASFFVV
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1351|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3278|M.marinum_M --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 TPPPNAVLGGLAPRFQGTESVLLAAAIMGATVMPHAVYLHSGLARDRHGH
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1351|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3278|M.marinum_M --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 PDPGPQRRRLLRVTRWDVGLAMLIAGGVNAAMLLVAALNMRGRGDTASIE
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1351|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3278|M.marinum_M --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 GAYHAVHDTLGATIAVLFAVGLLASGLASSSVGAYAGAMIMQGLLHWSVP
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1351|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3278|M.marinum_M --------------------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0948c|M.bovis_AF2122/97 MLVRRLITLGPALAILTLGFDPTRTLVLSQVVLSFGIPFAVLPLVKLTGS
Rv0925c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1351|M.ulcerans_Agy99 --------------------------------------
MMAR_3278|M.marinum_M --------------------------------------
Mflv_1969|M.gilvum_PYR-GCK --------------------------------------
Mvan_4745|M.vanbaalenii_PYR-1 --------------------------------------
MSMEG_1768|M.smegmatis_MC2_155 --------------------------------------
MAB_2520c|M.abscessus_ATCC_199 --------------------------------------
Mb0948c|M.bovis_AF2122/97 PAVMGGDTNHRATTWVGWVVAVMVSLLNVMLIYLTVTG
Rv0925c|M.tuberculosis_H37Rv --------------------------------------