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FNRCELVGGPPGSGSWVGMTCSTTSLGHGSKPFQRLPTWLGMVSDFLMATDKTALVLLHGGAGSGRAWQD VVPVVSRYHQVHAPTAPGHRGGPPVQRRPATAADERYLDEQGLQRPHLVGHSMGGYLAIELARRGRAATV CVFAPGGFWASGDGLRERTLSRALGGAGIARLMRPIMPLVLKSPRVRRLMFQDGACHGDRISAHRGIEIF DDFLGCTVANEVFSTDEEQIAPLDPLPCPVTVAWSEKDEIVPVTSYGPNARARLPQATFVTLPDVGHDPM VDDPELVARTILSVTTANAPQV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4213 | - | - | 100% (303) | hydrolase |
| M. ulcerans Agy99 | MUL_1440 | - | 2e-15 | 30.53% (190) | hypothetical protein MUL_1440 |
| M. ulcerans Agy99 | MUL_3358 | - | 8e-08 | 22.38% (286) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3370 | - | 6e-22 | 30.62% (258) | hypothetical protein Mb3370 |
| M. gilvum PYR-GCK | Mflv_4874 | - | 8e-19 | 28.74% (247) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3338 | - | 6e-17 | 29.85% (201) | hypothetical protein Rv3338 |
| M. leprae Br4923 | MLBr_00685 | - | 3e-22 | 29.96% (247) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_3685 | - | 6e-20 | 29.53% (254) | hypothetical protein MAB_3685 |
| M. marinum M | MMAR_1187 | - | 2e-19 | 31.05% (248) | hypothetical protein MMAR_1187 |
| M. avium 104 | MAV_4312 | - | 1e-23 | 32.39% (247) | hydrolase, alpha/beta fold family protein, putative |
| M. smegmatis MC2 155 | MSMEG_1655 | - | 6e-21 | 30.77% (247) | hydrolase, alpha/beta fold family protein, putative |
| M. thermoresistible (build 8) | TH_1972 | - | 7e-23 | 32.00% (250) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_1555 | - | 5e-19 | 29.07% (258) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
TH_1972|M.thermoresistible__bu ------------------------MSERAPIHLGSG--------------
Mvan_1555|M.vanbaalenii_PYR-1 ------------------------MNLREPIHLGSG--------------
MSMEG_1655|M.smegmatis_MC2_155 ------------------------MVERAPIHLGSRDG------------
Mflv_4874|M.gilvum_PYR-GCK ------------------------MAPREPIHRGTG--------------
Mb3370|M.bovis_AF2122/97 --MPSPSTTGHHAACGTGGTGFSVGSMRSPIRVGSG--------------
Rv3338|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1187|M.marinum_M --------------------------------------------------
MAV_4312|M.avium_104 --------------------------------------------------
MLBr_00685|M.leprae_Br4923 MPACQHQRHRPVVACGTRGTTFRVGSMRQPIHLGSG--------------
MAB_3685|M.abscessus_ATCC_1997 ---------------MLEAILSKPSNRRAPIEMGEG--------------
MUL_4213|M.ulcerans_Agy99 ------MFNRCELVGGPPGSGSWVGMTCSTTSLGHGSKPFQRLPTWLGMV
TH_1972|M.thermoresistible__bu ---------EPVLLLHPFMMSQSVWKDVAPRIAG----------TGRYEV
Mvan_1555|M.vanbaalenii_PYR-1 ---------EPVLLLHPFMMSQNVWKDVAPQLAGVDVANPSAPATGRYEV
MSMEG_1655|M.smegmatis_MC2_155 -------NTEPILLLHPFLLSQSVWKYVAPQLAD----------TGRYEV
Mflv_4874|M.gilvum_PYR-GCK ---------EPIVLLHPFLCSQNVWRTVADQLAD----------TERFEV
Mb3370|M.bovis_AF2122/97 ---------EPVLLLHPFLMSQTVWEKVAQQLAD----------TGRFEV
Rv3338|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1187|M.marinum_M -----------MLLLHPFLLSQAVWEQVAQRLAD----------TGRYEV
MAV_4312|M.avium_104 ------------MLLHGFLMSQTVWDPVAPRLAD----------TGRYEV
MLBr_00685|M.leprae_Br4923 ---------EPVLLLHPFMMSQTVWEIVAPQLAN----------TERYEV
MAB_3685|M.abscessus_ATCC_1997 ---------EPVLLLHPFMLSQSVWETVAEQLAD-----------AGYEV
MUL_4213|M.ulcerans_Agy99 SDFLMATDKTALVLLHGGAGSGRAWQDVVPVVSR------------YHQV
TH_1972|M.thermoresistible__bu YAPTMPGHNGG----VKGR-FFLDTAELADDMERRLDELGWDTAHIVGNS
Mvan_1555|M.vanbaalenii_PYR-1 LAPTMPGHNGG----VKGR-FFLDTAELADDMERRMDALGWDTAHVVGNS
MSMEG_1655|M.smegmatis_MC2_155 FAPTMADHNGG----PRGP-FLLDVAHLADDIERRMDEVGWTTAHIVGNS
Mflv_4874|M.gilvum_PYR-GCK FAPTMVGHHGG----PKSPTWLLHTEVLVDDIEHRMDQLGWDTAHIVGNS
Mb3370|M.bovis_AF2122/97 FAPTMAGHNGG----PASGTRFLSSAVLADHVERQLDELGWETSHIVGNS
Rv3338|M.tuberculosis_H37Rv ----------------------MSSAVLADHVERQLDELGWETSHIVGNS
MMAR_1187|M.marinum_M FAPTMASHNGG----PRAGTWFLSSAVLADHVERQMDELGWDSAHIVGNS
MAV_4312|M.avium_104 FAPTMAGHNGG----PYAGTWLLSSSVLADHVERQLDRLGWDSAHLVGNS
MLBr_00685|M.leprae_Br4923 FAPTMAAHHGG----PSASSWMMSVSTLADHVEQQLDELGWDTAHLVGNS
MAB_3685|M.abscessus_ATCC_1997 FAPTYPGHNGGGPMPKLPPFSQRSVDVYLDQIEQIMDQKGWETAHLVGNS
MUL_4213|M.ulcerans_Agy99 HAPTAPGHRGG---------PPVQRRPATAADERYLDEQGLQRPHLVGHS
*: :* * .*:**:*
TH_1972|M.thermoresistible__bu LGGWVAFELERRGRARTLTGIAPAGGWHRWSPAKYEIVGKFVLGFPVWAV
Mvan_1555|M.vanbaalenii_PYR-1 LGGWVAFELERRGRVRSLTAIAPAGGWHRWSLPKYEIVFKFVMGFPVWLT
MSMEG_1655|M.smegmatis_MC2_155 LGGWVAFELERRGRARTLTGIAPAGGWTRFTPAKYEIVAKFVGGLPIVLA
Mflv_4874|M.gilvum_PYR-GCK LGGWVAFELERRGRARTLTAIAPAGGWPHHSLSKYETVLKFIMGGPALIA
Mb3370|M.bovis_AF2122/97 LGGWVAFELERRGRARSVTGIAPAGGWTRWSPVKFEVIAKFIAGAPILAV
Rv3338|M.tuberculosis_H37Rv LGGWVAFELERRGRARSVTGIAPAGGWTRWSPVKFEVIAKFIAGAPILAV
MMAR_1187|M.marinum_M LGGWVAFELERRGRARSVTGIAPAGGWTRWSPAKFEVIIKFVMGIPLLAL
MAV_4312|M.avium_104 LGGWVAFELERRGRARSVTGIGAAGGWTRWSPVKFEVIGKFIGGMPLLLL
MLBr_00685|M.leprae_Br4923 LGGWVVFELERRGRARSVTGIAPAGGWTRWSLAKFEVIAKFVAGMPLVAV
MAB_3685|M.abscessus_ATCC_1997 LGGWIALGLALRGRARSVTAIAPAGGWTKYSPLKAEIVVKFAAMLPWLAF
MUL_4213|M.ulcerans_Agy99 MGGYLAIELARRGRAATVCVFAPGGFWASGDGLRERTLSRALGGAGIARL
:**::.: * ***. :: :...* * : . : :
TH_1972|M.thermoresistible__bu AKLLGRRAARLPIARQLAFVAVSAYPDGISDDDLVQIIDDVTHCAAYYQL
Mvan_1555|M.vanbaalenii_PYR-1 AKALGPRAARLPGARAAASVPVSATPDGISDADMLDIIDDVTHCAAYYQL
MSMEG_1655|M.smegmatis_MC2_155 TKLLGQRVHRLPFTRHISYVAVAATADSLTDDDRRDLIDDLAHCPAYHKL
Mflv_4874|M.gilvum_PYR-GCK ARLLGPRILNVPGARRLATLPVSGPADGPSQSDLAALVEDATHCSAYLQL
Mb3370|M.bovis_AF2122/97 AHILGQRALRLPFSRLLATLPISATPDGVSERELSGIIDDAAHCPAYFQL
Rv3338|M.tuberculosis_H37Rv AHILGQRALRLPFSRLLATLPISATPDGVSERELSGIIDDAAHCPAYFQL
MMAR_1187|M.marinum_M AWLLGPRVMRLPFSRRLATYAISASPDGVSDAELLGCIDDVAHCPAYLQL
MAV_4312|M.avium_104 ARLLGQRILQLPLSRRLATLPLSATPSGVSERQLSGVVEDAAHCPAYFQL
MLBr_00685|M.leprae_Br4923 ARGLGSRALSLPFSHRLASLPLTGSPAGLSEHQLRNIVEDAGHCPAYFLL
MAB_3685|M.abscessus_ATCC_1997 SRLLGRRAAGLPFAKFATARMLCGETEALSLPDFHSIFEDITHCPAYFAS
MUL_4213|M.ulcerans_Agy99 MRPIMPLVLKSPRVRRLMFQDGACHGDRISAHRGIEIFDDFLGCTVANEV
: * : : .:* *..
TH_1972|M.thermoresistible__bu LVKALLLPGLMELAETSVPTHLVVCEKDRVLPNPRFVDHFHKNLREITRY
Mvan_1555|M.vanbaalenii_PYR-1 LVKALLLPGLMELADTRIPTHMVICEKDRVLPHPRFVNHFRKHLPESTRF
MSMEG_1655|M.smegmatis_MC2_155 LLKSLTTAGLMELPNSCTPTHLVICEKDRVLPHPRFTRHFTRHLPANAEV
Mflv_4874|M.gilvum_PYR-GCK LVKTLRMPGLLELASLGAPTQLVLCEKDRVFPTPRGNRYFLTHLPDEARV
Mb3370|M.bovis_AF2122/97 LVKALVLPGLQELEHTAVPSHVVLCEQDRVVPPSRFSRHFTDSLPAGHRL
Rv3338|M.tuberculosis_H37Rv LVKALVLPGLQELEHTAVPSHVVLCEQDRVVPPSRFSRHFTDSLPAGHRL
MMAR_1187|M.marinum_M LVKALLLHGLRELAENAVPAHLVICGKDRIIPAPRYSRHFTTHLPDDHRV
MAV_4312|M.avium_104 LVKSLLQPGLLELAQTAVPVQLVLCEKDRVVPPSRFSRHFTDHLPPETRI
MLBr_00685|M.leprae_Br4923 LIKTLLQPGLRELADITVPVLLVLCEKDRVLPPPKYSRHFTDHLPERTQV
MAB_3685|M.abscessus_ATCC_1997 LTSILPAPGLENLDTISVPAQLVLCEKDEIVPPGRFGKLIGEGLPGNARR
MUL_4213|M.ulcerans_Agy99 FSTDEEQ--IAPLDPLPCPVTVAWSEKDEIVPVTSYGPNARARLPQAT-F
: . : * * :. . :*.:.* *
TH_1972|M.thermoresistible__bu TELDGVGHIPMFEAPQRVADLIVDFLDDHTG-KRRQASPGAVG
Mvan_1555|M.vanbaalenii_PYR-1 TALDGVGHIPMFEAPGRIADLIRDFLDEQID-GQRTTG-----
MSMEG_1655|M.smegmatis_MC2_155 THLDGVGHVPMFEAPGRVTELITEFVDRHTE-RGRAAG-----
Mflv_4874|M.gilvum_PYR-GCK VRLDGVGHIPMLEAPGAITELIADFVDDHSTPSGKAIG-----
Mb3370|M.bovis_AF2122/97 TVLDGVGHVPMFEAPGRITELITSFIEECCPHVRAS-------
Rv3338|M.tuberculosis_H37Rv TVLDGVGHVPMFEAPGRITELITSFIEECCPHVRAS-------
MMAR_1187|M.marinum_M TVLDNVGHVPMFEAPARVTALISGFIEECCPHLRSAEPPAS--
MAV_4312|M.avium_104 TRLDGVGHVPMFEAPERVTTVLTDFIDDCVARSQRQQPPAS--
MLBr_00685|M.leprae_Br4923 TKFDGMGHVPMFEAPEVITKLITNFINQCSKPAEAASPAS---
MAB_3685|M.abscessus_ATCC_1997 ITLAGMGHVPMLEAPGQVTEVITDLIDPLVSAKRSAASDAG--
MUL_4213|M.ulcerans_Agy99 VTLPDVGHDPMVDDPELVARTILSVTTANAPQV----------
: .:** **.: * :: : .