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TRPRPPIGPALAGAVDLSGLKQRAQQDTAAGGASGKAPADQPGVVEVTEANFEDEVIGRSDEVPVVVVLW SPRSDVCVELVDTLSGLAAADMGKWRLATVNVDVVPRVAQIFGVQAVPTVVALAAAQPISSFQGPQPAEQ LRLWVDSLLSATDGKLSGVAGSEDAEEVDPTVAQARAELEEGNFDAARGSYQAVLDANPNSVEAKAAIRQ IDFLSRATAQRPDAVLVADAAPDDVDAAFAAADVQVLSQDVTGAFERLVALVRRTSGDERTRVRTRLIEL FELFDPADPEVIAGRRSLASALY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3937 | - | - | 100% (304) | thioredoxin |
| M. ulcerans Agy99 | MUL_5067 | trxC | 5e-06 | 27.78% (90) | thioredoxin TrxC |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1359 | - | 1e-132 | 78.95% (304) | thioredoxin |
| M. gilvum PYR-GCK | Mflv_2342 | - | 1e-104 | 64.38% (306) | thioredoxin domain-containing protein |
| M. tuberculosis H37Rv | Rv1324 | - | 1e-132 | 78.95% (304) | thioredoxin |
| M. leprae Br4923 | MLBr_01159 | - | 1e-113 | 69.10% (301) | hypothetical protein MLBr_01159 |
| M. abscessus ATCC 19977 | MAB_1465 | - | 7e-91 | 58.97% (312) | hypothetical protein MAB_1465 |
| M. marinum M | MMAR_4074 | - | 1e-167 | 99.67% (304) | thioredoxin |
| M. avium 104 | MAV_1545 | - | 1e-127 | 76.39% (305) | thioredoxin domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4917 | - | 1e-115 | 69.74% (304) | TPR repeat-containing protein |
| M. thermoresistible (build 8) | TH_1534 | - | 1e-110 | 66.78% (304) | POSSIBLE THIOREDOXIN |
| M. vanbaalenii PYR-1 | Mvan_4303 | - | 1e-112 | 68.42% (304) | thioredoxin domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3937|M.ulcerans_Agy99 MTRPRPPIG--PALAGAVDLSGLKQRAQQDTAAGGASGKAPADQPG----
MMAR_4074|M.marinum_M MTRPRPPIG--PALAGAVDLSGLKQRAQQDTAAGGASGKAPADQPG----
Mb1359|M.bovis_AF2122/97 MTRPRPPLG--PAMAGAVDLSGIKQRAQQNAAASTDADRALSTPSG----
Rv1324|M.tuberculosis_H37Rv MTRPRPPLG--PAMAGAVDLSGIKQRAQQNAAASTDADRALSTPSG----
MLBr_01159|M.leprae_Br4923 -------------MAGAVDLSGLKQRARQKASTSDPASRATLGARGTGSS
MAV_1545|M.avium_104 MTRPRPSIG--PALAGAVDLSGLKQRAQAASGPAGGPAPADGGPG-----
MSMEG_4917|M.smegmatis_MC2_155 MTRPRPSIG--PALAGAVDLSALKRPAASGEAAPAPGGPNV---------
TH_1534|M.thermoresistible__bu VTRPGPSIG--PALAGAVDLSALKQRSAANQEGTGSAPPGG---------
Mflv_2342|M.gilvum_PYR-GCK MTRPGPRIS--SALAGAVDLSALKQRPASSAESASTGAPGG---------
Mvan_4303|M.vanbaalenii_PYR-1 MTRPGPRIS--PALAGAVDLSALKQR-ASAGGGAPAGNPGG---------
MAB_1465|M.abscessus_ATCC_1997 MTRPRPAVAAAAAMSGAVDLSALKQRAQEPASGEPSAGGEWT--------
::******.:*:
MUL_3937|M.ulcerans_Agy99 ----VVEVTEANFEDEVIGRSDEVPVVVVLWSPRSDVCVELVDTLSGLAA
MMAR_4074|M.marinum_M ----VVEVTEANFEDEVIGRSDEVPVVVVLWSPRSDVCVELVDTLSGLAA
Mb1359|M.bovis_AF2122/97 ----VTEITEANFEDEVIVRSDEVPVVVLLWSPRSEVCVDLLDTLSGLAA
Rv1324|M.tuberculosis_H37Rv ----VTEITEANFEDEVIVRSDEVPVVVLLWSPRSEVCVDLLDTLSGLAA
MLBr_01159|M.leprae_Br4923 ENTSVIEITEANFEDEVLVRSHEVPILVLVWSPRSDACVKLLETLSGLAV
MAV_1545|M.avium_104 ----ISAVTEANFEAEVLIRSEEVPVVVLLWSPRSDACVQLLDTLSGLAA
MSMEG_4917|M.smegmatis_MC2_155 -----TEVTEANFEAEVLVRSGQVPVVVVLWSPRSDASAQLTETFADLAS
TH_1534|M.thermoresistible__bu -----VEVTETNLEAEVLVRSTQVPVVVLLWTPRSDASVQLGNTLGTLAS
Mflv_2342|M.gilvum_PYR-GCK -----IEVTETNLEADVLVRSTEVPVVVLLWSPRSDASVQLGEALGALSA
Mvan_4303|M.vanbaalenii_PYR-1 -----VEVTEANLEAEVLVRSTEVPVVVLLWSPRSDSSVQLGDALAALSA
MAB_1465|M.abscessus_ATCC_1997 -----VEVTEANLESEVLAQSNRVPVIVLLGSPRSEASAALAATLGDLVA
:**:*:* :*: :* .**::*:: :***: .. * ::. *
MUL_3937|M.ulcerans_Agy99 ADMGKWRLATVNVDVVPRVAQIFGVQAVPTVVALAAAQPISSFQGPQPAE
MMAR_4074|M.marinum_M ADMGKWRLATVNVDVVPRVAQIFGVQAVPTVVALAAAQPISSFQGPQPAE
Mb1359|M.bovis_AF2122/97 AAKGKWSLASVNVDVAPRVAQIFGVQAVPTVVALAAGQPISSFQGLQPAD
Rv1324|M.tuberculosis_H37Rv AAKGKWSLASVNVDVAPRVAQIFGVQAVPTVVALAAGQPISSFQGLQPAD
MLBr_01159|M.leprae_Br4923 ADSGTWLLATVNVDAVPRVAQIFGVDAVPTVVALAAGQPLSSFQGMQSVD
MAV_1545|M.avium_104 QDNGKWSLATVNVDVAPRVAQIFGVDAVPTVVALAAGQPISSFQGMQPAD
MSMEG_4917|M.smegmatis_MC2_155 ADGGKWSLAAVNVDTTPRIAQMFGIQAVPTVVALAGGQPIASFQGPQPPE
TH_1534|M.thermoresistible__bu EDGGKWAFATVNVDTTPRVAQMFGVQAVPTVVALAGGQPISSFQGVQPAD
Mflv_2342|M.gilvum_PYR-GCK TDGAKWVFATVNVDTTPRVAQMFGVQAVPTVVALAAGRPLSSFEGMQPPD
Mvan_4303|M.vanbaalenii_PYR-1 ADGAKWTFATVNVDTTPRVAQMFGVQAVPTVVALAAGRPLSSFEGIQPPE
MAB_1465|M.abscessus_ATCC_1997 EDRGTWALARVNVDTNPQIAQVFGVQAVPTVVAVAAGRPLTSFTGPQPAD
..* :* ****. *::**:**::*******:*..:*::** * *. :
MUL_3937|M.ulcerans_Agy99 QLRLWVDSLLSATDGKLSGVAGSED---AEEVDPTVAQARAELEEGNFDA
MMAR_4074|M.marinum_M QLRLWVDSLLSATDGKLSGVAGSED---AEEVDPTVAQARAELEEGDFDA
Mb1359|M.bovis_AF2122/97 QLSRWVDSLLSATAGKLKGAASSEE---STEVDPAVAQARQQLEDGDFVA
Rv1324|M.tuberculosis_H37Rv QLSRWVDSLLSATAGKLKGAASSEE---STEVDPAVAQARQQLEDGDFVA
MLBr_01159|M.leprae_Br4923 QLRRWLDSLLSVTAGKLRGPTRSED---SAEIDPAIAQARQQLEAGDFLT
MAV_1545|M.avium_104 QLRGWLDQILSATAGKLKGATGSAE---SEAVDPELAAARQQLEAGDFEA
MSMEG_4917|M.smegmatis_MC2_155 QLRRWVDSLLEATAGKLSGS-GEE----AEQVDPALAQARAHLDQGNFDE
TH_1534|M.thermoresistible__bu QLRRWIDSLLNATAGKLSGPPGEEQ---AEQVDPEVAQARAQLDAGDFDG
Mflv_2342|M.gilvum_PYR-GCK QLRRWIDSLLNAVAGKLSGAGDEGQ---PEEVDPQLEQARALLDEGDFDA
Mvan_4303|M.vanbaalenii_PYR-1 QLRRWIDSLLNAVAGKLGGTGEDEQ---AEAVDPEVEQARAHLDAGDFEA
MAB_1465|M.abscessus_ATCC_1997 QLRRWLDSILDAVAGKLPDAPVSDDEDTEEAVDPALAAARDALDSGDFEA
** *:*.:*... *** . . :** : ** *: *:*
MUL_3937|M.ulcerans_Agy99 ARGSYQAVLDANPN---SVEAKAAIRQIDFLSRATAQRPDAVLVADAAPD
MMAR_4074|M.marinum_M ARGSYQAVLDANPN---SVEAKAAIRQIDFLSRATAQRPDAVLVADAAPD
Mb1359|M.bovis_AF2122/97 ARKSYQAILDANPG---SVEAKAAIRQIEFLIRATAQRPDAVSVADSLSD
Rv1324|M.tuberculosis_H37Rv ARKSYQAILDANPG---SVEAKAAIRQIEFLIRATAQRPDAVSVADSLSD
MLBr_01159|M.leprae_Br4923 AKQSYHAILDADPA---SVEAKAAIRQIDFLTRATAQHPDAVAVADAAPG
MAV_1545|M.avium_104 ARTSYQAILDANPA---SAEAKGAIRQIDFLTRATAQRPDAVAVADAAPG
MSMEG_4917|M.smegmatis_MC2_155 ALKAYEAILEAQPN---HPEAKGAVRQIGFLQRATAQRPDAVEVADAAPD
TH_1534|M.thermoresistible__bu ALKSYKAILETRPN---HPEAKGAVRQIEFLQRATKHSPDAIATADAAPD
Mflv_2342|M.gilvum_PYR-GCK ARNAYQAILDADPN---HAEAKGAVRQIGFLQRATTHPQDAVAIADAAPD
Mvan_4303|M.vanbaalenii_PYR-1 AQSAYQAILDANPN---HDEAKGAVRQIGFLQRATAHPRDAIAVADASPN
MAB_1465|M.abscessus_ATCC_1997 ARTAYQGLLDGGATGAVAAEATASVRQIAFLIRATGQPQDAVLTANAAPG
* :*..:*: . **..::*** ** *** : **: *:: ..
MUL_3937|M.ulcerans_Agy99 DVDAAFAAADVQVLSQDVTGAFERLVALVRRTSGDERTRVRTRLIELFEL
MMAR_4074|M.marinum_M DVDAAFAAADVQVLSQDVTGAFERLVALVRRTSGDERTRVRTRLIELFEL
Mb1359|M.bovis_AF2122/97 DIDAAFAAADVQVLNQDVSAAFERLIALVRRTSGEERTRVRTRLIELFEL
Rv1324|M.tuberculosis_H37Rv DIDAAFAAADVQVLNQDVSAAFERLIALVRRTSGEERTRVRTRLIELFEL
MLBr_01159|M.leprae_Br4923 DIAAAFAAADVQILNQDVTAAFERLIVLVRSTSGDERSSVRTRLIELFEL
MAV_1545|M.avium_104 DIDAAFAAADVQILNQDVGAAFDRLIALVRNTSGDDRARVRTRLVELFDL
MSMEG_4917|M.smegmatis_MC2_155 DIEAAFAAADVEILAQQVSAAFDRLIALIKRTAGDDRTKVRTRLIELFEL
TH_1534|M.thermoresistible__bu DIDAAFAAADVEILQQQVTAAFDRLIDLVKRTSGDDRAKVRSRLVELFEL
Mflv_2342|M.gilvum_PYR-GCK DIAAALAAADVEILQQQIEPAFARLTALVRRTAGDDRTTVRTRLIELFDL
Mvan_4303|M.vanbaalenii_PYR-1 DIDAAFAAADVEILQQDVQAAFTRLTALVKRTAGDDRTKVRTRLIELFDL
MAB_1465|M.abscessus_ATCC_1997 DIDAGLAAADVEVLSQQPDSAFDRLVALVRGTSDDDRAKVRARLLELFEL
*: *.:*****::* *: ** ** *:: *:.::*: **:**:***:*
MUL_3937|M.ulcerans_Agy99 FDPADPEVIAGRRSLASALY
MMAR_4074|M.marinum_M FDPADPEVIAGRRSLASALY
Mb1359|M.bovis_AF2122/97 FDPADPEVVAGRRNLANALY
Rv1324|M.tuberculosis_H37Rv FDPADPEVVAGRRNLANALY
MLBr_01159|M.leprae_Br4923 FDPDDPNVIVGRRNLANALY
MAV_1545|M.avium_104 FDPADPEVVAGRRNLANALY
MSMEG_4917|M.smegmatis_MC2_155 FDPADPEVIAGRRNLANALY
TH_1534|M.thermoresistible__bu FDPSDPQVLTARRNLASALY
Mflv_2342|M.gilvum_PYR-GCK FDPADPAVIAGRRNLANALY
Mvan_4303|M.vanbaalenii_PYR-1 FDPADPEVVAGRRNLANALY
MAB_1465|M.abscessus_ATCC_1997 FDPADPAVIAGRRKLANALF
*** ** *:..**.**.**: