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M. avium 104 MAV_1545 (-)

annotation: thioredoxin domain-containing protein
coordinates: 1502757 - 1503668
length: 303

VTRPRPSIGPALAGAVDLSGLKQRAQAASGPAGGPAPADGGPGISAVTEANFEAEVLIRSEEVPVVVLLW
SPRSDACVQLLDTLSGLAAQDNGKWSLATVNVDVAPRVAQIFGVDAVPTVVALAAGQPISSFQGMQPADQ
LRGWLDQILSATAGKLKGATGSAESEAVDPELAAARQQLEAGDFEAARTSYQAILDANPASAEAKGAIRQ
IDFLTRATAQRPDAVAVADAAPGDIDAAFAAADVQILNQDVGAAFDRLIALVRNTSGDDRARVRTRLVEL
FDLFDPADPEVVAGRRNLANALY
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1545--100% (303)thioredoxin domain-containing protein
M. avium 104MAV_5302trx4e-0729.55% (88) thioredoxin

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1359-1e-12776.64% (304) thioredoxin
M. gilvum PYR-GCKMflv_2342-1e-10766.67% (303) thioredoxin domain-containing protein
M. tuberculosis H37RvRv1324-1e-12776.64% (304) thioredoxin
M. leprae Br4923MLBr_01159-1e-11772.76% (301) hypothetical protein MLBr_01159
M. abscessus ATCC 19977MAB_1465-6e-9762.06% (311) hypothetical protein MAB_1465
M. marinum MMMAR_4074-1e-12776.72% (305) thioredoxin
M. smegmatis MC2 155MSMEG_4917-1e-11570.30% (303) TPR repeat-containing protein
M. thermoresistible (build 8)TH_1534-1e-11369.64% (303) POSSIBLE THIOREDOXIN
M. ulcerans Agy99MUL_3937-1e-12776.39% (305) thioredoxin
M. vanbaalenii PYR-1Mvan_4303-1e-11571.29% (303) thioredoxin domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1359|M.bovis_AF2122/97            MTRPRPPLG--PAMAGAVDLSGIKQRAQQNAAASTDADRALSTPSG----
Rv1324|M.tuberculosis_H37Rv         MTRPRPPLG--PAMAGAVDLSGIKQRAQQNAAASTDADRALSTPSG----
MMAR_4074|M.marinum_M               MTRPRPPIG--PALAGAVDLSGLKQRAQQDTAAGGASGKAPADQPG----
MUL_3937|M.ulcerans_Agy99           MTRPRPPIG--PALAGAVDLSGLKQRAQQDTAAGGASGKAPADQPG----
MLBr_01159|M.leprae_Br4923          -------------MAGAVDLSGLKQRARQKASTSDPASRATLGARGTGSS
MAV_1545|M.avium_104                MTRPRPSIG--PALAGAVDLSGLKQRAQAASGPAGGPAPADGGPG-----
MSMEG_4917|M.smegmatis_MC2_155      MTRPRPSIG--PALAGAVDLSALKRPAASGEAAPAPGGPNV---------
TH_1534|M.thermoresistible__bu      VTRPGPSIG--PALAGAVDLSALKQRSAANQEGTGSAPPGG---------
Mflv_2342|M.gilvum_PYR-GCK          MTRPGPRIS--SALAGAVDLSALKQRPASSAESASTGAPGG---------
Mvan_4303|M.vanbaalenii_PYR-1       MTRPGPRIS--PALAGAVDLSALKQR-ASAGGGAPAGNPGG---------
MAB_1465|M.abscessus_ATCC_1997      MTRPRPAVAAAAAMSGAVDLSALKQRAQEPASGEPSAGGEWT--------
                                                 ::******.:*:                         

Mb1359|M.bovis_AF2122/97            ----VTEITEANFEDEVIVRSDEVPVVVLLWSPRSEVCVDLLDTLSGLAA
Rv1324|M.tuberculosis_H37Rv         ----VTEITEANFEDEVIVRSDEVPVVVLLWSPRSEVCVDLLDTLSGLAA
MMAR_4074|M.marinum_M               ----VVEVTEANFEDEVIGRSDEVPVVVVLWSPRSDVCVELVDTLSGLAA
MUL_3937|M.ulcerans_Agy99           ----VVEVTEANFEDEVIGRSDEVPVVVVLWSPRSDVCVELVDTLSGLAA
MLBr_01159|M.leprae_Br4923          ENTSVIEITEANFEDEVLVRSHEVPILVLVWSPRSDACVKLLETLSGLAV
MAV_1545|M.avium_104                ----ISAVTEANFEAEVLIRSEEVPVVVLLWSPRSDACVQLLDTLSGLAA
MSMEG_4917|M.smegmatis_MC2_155      -----TEVTEANFEAEVLVRSGQVPVVVVLWSPRSDASAQLTETFADLAS
TH_1534|M.thermoresistible__bu      -----VEVTETNLEAEVLVRSTQVPVVVLLWTPRSDASVQLGNTLGTLAS
Mflv_2342|M.gilvum_PYR-GCK          -----IEVTETNLEADVLVRSTEVPVVVLLWSPRSDASVQLGEALGALSA
Mvan_4303|M.vanbaalenii_PYR-1       -----VEVTEANLEAEVLVRSTEVPVVVLLWSPRSDSSVQLGDALAALSA
MAB_1465|M.abscessus_ATCC_1997      -----VEVTEANLESEVLAQSNRVPVIVLLGSPRSEASAALAATLGDLVA
                                           :**:*:* :*: :* .**::*:: :***: .. *  ::. *  

Mb1359|M.bovis_AF2122/97            AAKGKWSLASVNVDVAPRVAQIFGVQAVPTVVALAAGQPISSFQGLQPAD
Rv1324|M.tuberculosis_H37Rv         AAKGKWSLASVNVDVAPRVAQIFGVQAVPTVVALAAGQPISSFQGLQPAD
MMAR_4074|M.marinum_M               ADMGKWRLATVNVDVVPRVAQIFGVQAVPTVVALAAAQPISSFQGPQPAE
MUL_3937|M.ulcerans_Agy99           ADMGKWRLATVNVDVVPRVAQIFGVQAVPTVVALAAAQPISSFQGPQPAE
MLBr_01159|M.leprae_Br4923          ADSGTWLLATVNVDAVPRVAQIFGVDAVPTVVALAAGQPLSSFQGMQSVD
MAV_1545|M.avium_104                QDNGKWSLATVNVDVAPRVAQIFGVDAVPTVVALAAGQPISSFQGMQPAD
MSMEG_4917|M.smegmatis_MC2_155      ADGGKWSLAAVNVDTTPRIAQMFGIQAVPTVVALAGGQPIASFQGPQPPE
TH_1534|M.thermoresistible__bu      EDGGKWAFATVNVDTTPRVAQMFGVQAVPTVVALAGGQPISSFQGVQPAD
Mflv_2342|M.gilvum_PYR-GCK          TDGAKWVFATVNVDTTPRVAQMFGVQAVPTVVALAAGRPLSSFEGMQPPD
Mvan_4303|M.vanbaalenii_PYR-1       ADGAKWTFATVNVDTTPRVAQMFGVQAVPTVVALAAGRPLSSFEGIQPPE
MAB_1465|M.abscessus_ATCC_1997      EDRGTWALARVNVDTNPQIAQVFGVQAVPTVVAVAAGRPLTSFTGPQPAD
                                       ..* :* ****. *::**:**::*******:*..:*::** * *. :

Mb1359|M.bovis_AF2122/97            QLSRWVDSLLSATAGKLKGAASSEE---STEVDPAVAQARQQLEDGDFVA
Rv1324|M.tuberculosis_H37Rv         QLSRWVDSLLSATAGKLKGAASSEE---STEVDPAVAQARQQLEDGDFVA
MMAR_4074|M.marinum_M               QLRLWVDSLLSATDGKLSGVAGSED---AEEVDPTVAQARAELEEGDFDA
MUL_3937|M.ulcerans_Agy99           QLRLWVDSLLSATDGKLSGVAGSED---AEEVDPTVAQARAELEEGNFDA
MLBr_01159|M.leprae_Br4923          QLRRWLDSLLSVTAGKLRGPTRSED---SAEIDPAIAQARQQLEAGDFLT
MAV_1545|M.avium_104                QLRGWLDQILSATAGKLKGATGSAE---SEAVDPELAAARQQLEAGDFEA
MSMEG_4917|M.smegmatis_MC2_155      QLRRWVDSLLEATAGKLSGS-GEE----AEQVDPALAQARAHLDQGNFDE
TH_1534|M.thermoresistible__bu      QLRRWIDSLLNATAGKLSGPPGEEQ---AEQVDPEVAQARAQLDAGDFDG
Mflv_2342|M.gilvum_PYR-GCK          QLRRWIDSLLNAVAGKLSGAGDEGQ---PEEVDPQLEQARALLDEGDFDA
Mvan_4303|M.vanbaalenii_PYR-1       QLRRWIDSLLNAVAGKLGGTGEDEQ---AEAVDPEVEQARAHLDAGDFEA
MAB_1465|M.abscessus_ATCC_1997      QLRRWLDSILDAVAGKLPDAPVSDDEDTEEAVDPALAAARDALDSGDFEA
                                    **  *:*.:*... *** .   .        :** :  **  *: *:*  

Mb1359|M.bovis_AF2122/97            ARKSYQAILDANPG---SVEAKAAIRQIEFLIRATAQRPDAVSVADSLSD
Rv1324|M.tuberculosis_H37Rv         ARKSYQAILDANPG---SVEAKAAIRQIEFLIRATAQRPDAVSVADSLSD
MMAR_4074|M.marinum_M               ARGSYQAVLDANPN---SVEAKAAIRQIDFLSRATAQRPDAVLVADAAPD
MUL_3937|M.ulcerans_Agy99           ARGSYQAVLDANPN---SVEAKAAIRQIDFLSRATAQRPDAVLVADAAPD
MLBr_01159|M.leprae_Br4923          AKQSYHAILDADPA---SVEAKAAIRQIDFLTRATAQHPDAVAVADAAPG
MAV_1545|M.avium_104                ARTSYQAILDANPA---SAEAKGAIRQIDFLTRATAQRPDAVAVADAAPG
MSMEG_4917|M.smegmatis_MC2_155      ALKAYEAILEAQPN---HPEAKGAVRQIGFLQRATAQRPDAVEVADAAPD
TH_1534|M.thermoresistible__bu      ALKSYKAILETRPN---HPEAKGAVRQIEFLQRATKHSPDAIATADAAPD
Mflv_2342|M.gilvum_PYR-GCK          ARNAYQAILDADPN---HAEAKGAVRQIGFLQRATTHPQDAVAIADAAPD
Mvan_4303|M.vanbaalenii_PYR-1       AQSAYQAILDANPN---HDEAKGAVRQIGFLQRATAHPRDAIAVADASPN
MAB_1465|M.abscessus_ATCC_1997      ARTAYQGLLDGGATGAVAAEATASVRQIAFLIRATGQPQDAVLTANAAPG
                                    *  :*..:*:  .      **..::*** ** *** :  **:  *:: ..

Mb1359|M.bovis_AF2122/97            DIDAAFAAADVQVLNQDVSAAFERLIALVRRTSGEERTRVRTRLIELFEL
Rv1324|M.tuberculosis_H37Rv         DIDAAFAAADVQVLNQDVSAAFERLIALVRRTSGEERTRVRTRLIELFEL
MMAR_4074|M.marinum_M               DVDAAFAAADVQVLSQDVTGAFERLVALVRRTSGDERTRVRTRLIELFEL
MUL_3937|M.ulcerans_Agy99           DVDAAFAAADVQVLSQDVTGAFERLVALVRRTSGDERTRVRTRLIELFEL
MLBr_01159|M.leprae_Br4923          DIAAAFAAADVQILNQDVTAAFERLIVLVRSTSGDERSSVRTRLIELFEL
MAV_1545|M.avium_104                DIDAAFAAADVQILNQDVGAAFDRLIALVRNTSGDDRARVRTRLVELFDL
MSMEG_4917|M.smegmatis_MC2_155      DIEAAFAAADVEILAQQVSAAFDRLIALIKRTAGDDRTKVRTRLIELFEL
TH_1534|M.thermoresistible__bu      DIDAAFAAADVEILQQQVTAAFDRLIDLVKRTSGDDRAKVRSRLVELFEL
Mflv_2342|M.gilvum_PYR-GCK          DIAAALAAADVEILQQQIEPAFARLTALVRRTAGDDRTTVRTRLIELFDL
Mvan_4303|M.vanbaalenii_PYR-1       DIDAAFAAADVEILQQDVQAAFTRLTALVKRTAGDDRTKVRTRLIELFDL
MAB_1465|M.abscessus_ATCC_1997      DIDAGLAAADVEVLSQQPDSAFDRLVALVRGTSDDDRAKVRARLLELFEL
                                    *: *.:*****::* *:   ** **  *:: *:.::*: **:**:***:*

Mb1359|M.bovis_AF2122/97            FDPADPEVVAGRRNLANALY
Rv1324|M.tuberculosis_H37Rv         FDPADPEVVAGRRNLANALY
MMAR_4074|M.marinum_M               FDPADPEVIAGRRSLASALY
MUL_3937|M.ulcerans_Agy99           FDPADPEVIAGRRSLASALY
MLBr_01159|M.leprae_Br4923          FDPDDPNVIVGRRNLANALY
MAV_1545|M.avium_104                FDPADPEVVAGRRNLANALY
MSMEG_4917|M.smegmatis_MC2_155      FDPADPEVIAGRRNLANALY
TH_1534|M.thermoresistible__bu      FDPSDPQVLTARRNLASALY
Mflv_2342|M.gilvum_PYR-GCK          FDPADPAVIAGRRNLANALY
Mvan_4303|M.vanbaalenii_PYR-1       FDPADPEVVAGRRNLANALY
MAB_1465|M.abscessus_ATCC_1997      FDPADPAVIAGRRKLANALF
                                    *** ** *:..**.**.**: