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M. avium 104 MAV_1728 (-)

annotation: Rne protein
coordinates: 1703516 - 1706365
length: 949

VVDGAPTADPSEESTRSGDLPDRLRVHSLARTLGTTSKRVLDALSELDGRVRSAHSTVDREDAVRVRDLL
AAQPSAELEPAAEDAASGGPDAGITGEPESRLLLETPDATERPHYMPLFVAPQPLESSDDDGDADETADS
DDSDGDDDEQADRPSSRRRRRGRRGRGRGRGEQGGSDGPGDGDNDEPQNRGKKGGQSDGDDDSDGQDAED
ADDSDTGDDGSADGGNRRRRRRRRRKSGSGDDNEDGPSPDDPPNTVVHERPPRNGKNGGDDGNGSSSSEI
KGIDGSTRLEAKRQRRRDGRDAGRRRPPVLTEAEFLARREAVERVMVVRDRIRTEPPHQGSRYTQIAVLE
DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWEAAGLGGSDRKIEQA
LKPGDYVVVQVSKDPVGHKGARLTTQVSLAGRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAG
VIIRTASEGVKEDDIRGDVTRLQERWKQIEAKAIEIKEKAAGAAVALYEEPDVLVKVIRDLFNEDFAGLI
VSGDDAWNTINEYVNSVAPDLVSKVTKYEPATGPDGTPGPDVFAVHRIDEQLAKAMDRKVWLPSGGTLVI
DRTEAMTVIDVNTGKFTGSGGNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTSCPNCGGRGILLHADPVDSAPSNGRKSESG
GRRGRRKKSKAEEPVVAKVPVHSPGEHPMFKAMAAGSSTQAASDEDESAAEEAGDELERKKAARAEELEA
AEDTEDLEDTEDDDEDSDDSDDSDDEDLDDEDIDDEEDLGDDDEDLELDDDDLDTEDSDDSDDSDDSEDS
DDSEDQRDPAAECPGVSALGRPRRRRAAGRPAGPPIHAD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1728--100% (949)Rne protein
M. avium 104MAV_1514rho6e-0726.50% (234) transcription termination factor Rho
M. avium 104MAV_3595-1e-0631.21% (141) RNA polymerase sigma factor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2471crne0.074.92% (977) ribonuclease E
M. gilvum PYR-GCKMflv_2634-0.066.57% (1002) ribonuclease
M. tuberculosis H37RvRv2444crne0.074.92% (977) ribonuclease E
M. leprae Br4923MLBr_01468-0.074.95% (958) putative ribonuclease
M. abscessus ATCC 19977MAB_1607-0.061.16% (986) ribonuclease E
M. marinum MMMAR_3768rne0.073.19% (1022) ribonuclease E Rne
M. smegmatis MC2 155MSMEG_4626-0.065.34% (1059) ribonuclease, Rne/Rng family protein
M. thermoresistible (build 8)TH_0997rne0.070.73% (779) POSSIBLE RIBONUCLEASE E RNE
M. ulcerans Agy99MUL_3715rne0.075.35% (994) ribonuclease E Rne
M. vanbaalenii PYR-1Mvan_3947-0.069.78% (973) ribonuclease

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2634|M.gilvum_PYR-GCK          MADNENLQDSNHELGEEPQRLAE---TPSQAKSAPASEKLRVHSLARVLG
Mvan_3947|M.vanbaalenii_PYR-1       MADNENFEAATHDLTDEPQLAAD---SSGSAKDAPAPERLRVHSLARVLG
MSMEG_4626|M.smegmatis_MC2_155      MAEDAHTEDLS---TQTPQQEG-------------LPERLRVHSLARVLG
MMAR_3768|M.marinum_M               MVDGAPSSDPENEPTQRE----------------DLPDRLRVHSLARTLG
MUL_3715|M.ulcerans_Agy99           MVDGAPSSDPENEPTQRE----------------DLPDRLRVHSLARTLG
Mb2471c|M.bovis_AF2122/97           MIDGAPPSDPP-EPSQHE----------------ELPDRLRVHSLARTLG
Rv2444c|M.tuberculosis_H37Rv        MIDGAPPSDPP-EPSQHE----------------ELPDRLRVHSLARTLG
MLBr_01468|M.leprae_Br4923          MIDGAPPLEPSKEPTQHM----------------ELPDRLRVHSLARTLG
MAV_1728|M.avium_104                MVDGAPTADPSEESTRSG----------------DLPDRLRVHSLARTLG
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997      MADYELPEDLHTSAPEGEHAALTPDTPPAPAEQGELPEKLRVHSLARVLG
                                                                                      

Mflv_2634|M.gilvum_PYR-GCK          TTSRRIIDALAELDGRARSAHSTVGPDEADRVREVLAAPEPETTP-----
Mvan_3947|M.vanbaalenii_PYR-1       TTSRRIIDALVELDGRTRSAHSTVGREEADRVREVLAEP-----------
MSMEG_4626|M.smegmatis_MC2_155      TTSRRVLDALAEFDGRQRSAHSTVDKADAERVRAALTESPAAETPPEEAP
MMAR_3768|M.marinum_M               TSSRRVLDALSALDGRIRSAHSSVDRVDAVRVRDLLAEQP----------
MUL_3715|M.ulcerans_Agy99           TSSRRVLDALSALDGRIRSAHSSVDRVDAVRVRDLLAEQP----------
Mb2471c|M.bovis_AF2122/97           TTSRRVLDALTALDGRVRSAHSTVDRVDAVRVRDLLATHL----------
Rv2444c|M.tuberculosis_H37Rv        TTSRRVLDALTALDGRVRSAHSTVDRVDAVRVRDLLATHL----------
MLBr_01468|M.leprae_Br4923          TTSRRVLDVLSALDGRIRSAHSSVDRVDAVRVRDLLASQP----------
MAV_1728|M.avium_104                TTSKRVLDALSELDGRVRSAHSTVDREDAVRVRDLLAAQP----------
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997      TSTRRVLDALSNLDGRARSPHSNVDKQDAAKVREVLANEA----------
                                                                                      

Mflv_2634|M.gilvum_PYR-GCK          -------------EQVTEVATDAVEAQAEPQPEAQ-----AQSEAQAQPQ
Mvan_3947|M.vanbaalenii_PYR-1       -----------------EVAT--------PEPDPE-----ASTPEPAAPE
MSMEG_4626|M.smegmatis_MC2_155      AAETPVADLVVVQAEQVEVVTVSEAGPAEPAEPAEPEAPAAEAEAEAETE
MMAR_3768|M.marinum_M               ----------------------------AEEGQAEEGQQAPDAVAAEVPD
MUL_3715|M.ulcerans_Agy99           ----------------------------AEEGQAEEDQQAPDAVAAEVPD
Mb2471c|M.bovis_AF2122/97           ----------------------------ETAG-----------VLAASVH
Rv2444c|M.tuberculosis_H37Rv        ----------------------------ETAG-----------VLAASVH
MLBr_01468|M.leprae_Br4923          ----------------------------NSPH-----------ELTAVPD
MAV_1728|M.avium_104                ----------------------------SAELEP--------AAEDAASG
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997      ---------------------------EAAPVVAETPAPVAAEEAPAVVT
                                                                                      

Mflv_2634|M.gilvum_PYR-GCK          PGPEAPAPEAPAE------EEPESRLILETPSAPS----TAEPADYLPLF
Mvan_3947|M.vanbaalenii_PYR-1       LQAPDVDAETVTE------DEPESRLILETPVAP-----VSEPADYLPLF
MSMEG_4626|M.smegmatis_MC2_155      VADEAETPEPTFRGAVLVGDEPESRLILEHANIPPARETQTERPDYLPLF
MMAR_3768|M.marinum_M               APGE--PAEPDEP---------ESRLMLETQETVQVVETWVERPHYMPLF
MUL_3715|M.ulcerans_Agy99           APGE--PAEP------------ESRLMLETQETVQVVETWVERPHYMPLF
Mb2471c|M.bovis_AF2122/97           APEA--SEEP------------ESRLMLETQE---TRNADVERPHYMPLF
Rv2444c|M.tuberculosis_H37Rv        APEA--SEEP------------ESRLMLETQE---TRNADVERPHYMPLF
MLBr_01468|M.leprae_Br4923          NPVA--LEER------------DSRLVLET---------TVERPHYMPLF
MAV_1728|M.avium_104                GPDAGITGEP------------ESRLLLETPD-------ATERPHYMPLF
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997      GDSADSAEDPDNP--PTTPILIAEATVIEAAAVPVPAAAAPTAYDYGPLF
                                                                                      

Mflv_2634|M.gilvum_PYR-GCK          VAPQPVRFEDRYEDSDDDDEDASDSDD---SDDSDSDSDDDQSGRPAAKR
Mvan_3947|M.vanbaalenii_PYR-1       VAPQPVRFDEHDHD-DDDGDDVDDDGD---DVDSESDSDEDQPGRPAAKR
MSMEG_4626|M.smegmatis_MC2_155      VAPQPVSFEPAVVDDEDEDDDTETGAESDFDSGADSDSDDDQADRP--RR
MMAR_3768|M.marinum_M               VAPQPISEPVAGDDADDESGDEGDD-------------DEEQADRPANRR
MUL_3715|M.ulcerans_Agy99           VAPQPISEPVAGDDADDESGDEGDD-------------DEEQADRPGNRR
Mb2471c|M.bovis_AF2122/97           VAPQPIPEPLADDEDVDDGPDYVADDS--------DADDEGQLDRPANRR
Rv2444c|M.tuberculosis_H37Rv        VAPQPIPEPLADDEDVDDGPDYVADDS--------DADDEGQLDRPANRR
MLBr_01468|M.leprae_Br4923          VAPQPI--EVDDDSCADDDVESGDDSD--------VGDDEEQPDRPANRR
MAV_1728|M.avium_104                VAPQPLE-SSDDDGDADETADSDDSD----------GDDDEQADRPSSRR
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997      VAPQAPEPQERPAPVRTEKAEDVDEDAG---ETDDSDADGEGDGDRPARR
                                                                                      

Mflv_2634|M.gilvum_PYR-GCK          RRRGRRGRGRGRGEQNGDEPSDADGDS--------DGDAETEKARSDDSE
Mvan_3947|M.vanbaalenii_PYR-1       RRRGRRGRGRGRGEQNGDESS-ADSD---------EGDVDTEKAQSGESA
MSMEG_4626|M.smegmatis_MC2_155      RRRGRRGRGRGRGEQNDDATSDADTDS--------TEDQTDGDEQ--ESG
MMAR_3768|M.marinum_M               RRRGRRGRGRGRGEQGANDGQDQPGDDGDEAPQKTGGNSTSSDDTEAQDG
MUL_3715|M.ulcerans_Agy99           RRRGRRGRGRGRGEQGANDGQDQPGDDGDEAPQKAGGNSTSSDDSEAQDG
Mb2471c|M.bovis_AF2122/97           RRRGRRGRGRGRGEQGGSDGDPVDQQSEPRAQQFTSADAAETDDGDDRDS
Rv2444c|M.tuberculosis_H37Rv        RRRGRRGRGRGRGEQGGSDGDPVDQQSEPRAQQFTSADAAETDDGDDRDS
MLBr_01468|M.leprae_Br4923          RRRGRRGRGRGRGEQGGSDVQSDDVDG--------AVDSTESEDFDGQDF
MAV_1728|M.avium_104                RRRGRRGRGRGRGEQGGSDGPGDGDNDEPQNRGKKGGQSDGDDDSDGQDA
TH_0997|M.thermoresistible__bu      --------------------------------------------------
MAB_1607|M.abscessus_ATCC_1997      RRRGRRGRGRGRGEQGGGEGSDDSGDD-AAAEGGEAAEGDDAADGTGDDS
                                                                                      

Mflv_2634|M.gilvum_PYR-GCK          DDNGEDDNGDDDGAGGDAGTRRRRRRRRRKSGSDDDN---GSGGSPDDPP
Mvan_3947|M.vanbaalenii_PYR-1       DDS-DDDSGEDDGTGADGATRRRRRRRRRKSGSDDD----GENGSPDDPP
MSMEG_4626|M.smegmatis_MC2_155      EDS--DDSGDEDSTTTEGGTRRRRRRRRRKSGSGDS----DDAVSPDDPP
MMAR_3768|M.marinum_M               ADSEESDNGDDDNGSADGANRRRRRRRRRKSGAGDDGD---EGPAPDDPP
MUL_3715|M.ulcerans_Agy99           ADSEESDNGDDDNGSADGASRRRRRRRRRKSGAGDDGD---EGPAPDDPP
Mb2471c|M.bovis_AF2122/97           EDTEAGDNGEDENGSLEAGNRRRRRRRRRKSASGDDNDAALEGPLPDDPP
Rv2444c|M.tuberculosis_H37Rv        EDTEAGDNGEDENGSLEAGNRRRRRRRRRKSASGDDNDAALEGPLPDDPP
MLBr_01468|M.leprae_Br4923          DESEDTEIGYDESGSSEAGNRRRRRRRRRKSGVGED-----EGCAPDDPP
MAV_1728|M.avium_104                EDADDSDTGDD--GSADGGNRRRRRRRRRKSGSGDDNE---DGPSPDDPP
TH_0997|M.thermoresistible__bu      -------------------------------------------VSPDDPP
MAB_1607|M.abscessus_ATCC_1997      PAPDGDESNAEDGDTPEGASRRRRRRRRRKAGSGDDG----DGPSDDDPP
                                                                                  ****

Mflv_2634|M.gilvum_PYR-GCK          NTVVHEREPRKSG-RADKGDK-----SDEIQGISGSTRLEAKRQRRRDGR
Mvan_3947|M.vanbaalenii_PYR-1       NTVVHEREPRKSANRGDKTSS-----DSEIQGISGSTRLEAKRQRRRDGR
MSMEG_4626|M.smegmatis_MC2_155      NTVVHERAPRTER--SDKSD------DSEIQGISGSTRLEAKRQRRRDGR
MMAR_3768|M.marinum_M               NTVVHERAPRSGGKSGNSDSG-DDSGGNEIKGIDGSTRLEAKRQRRRDGR
MUL_3715|M.ulcerans_Agy99           NTVVHERAPRSGDKSGNSDSG-DDSGGNEIKGIDGSTRLEAKRQRRRDGR
Mb2471c|M.bovis_AF2122/97           NTVVHERVPRAGDKAGNSQD--GGSGSTEIKGIDGSTRLEAKRQRRRDGR
Rv2444c|M.tuberculosis_H37Rv        NTVVHERVPRAGDKAGNSQD--GGSGSTEIKGIDGSTRLEAKRQRRRDGR
MLBr_01468|M.leprae_Br4923          NTVVHERTPRAAGRSASFDNGVNGTGSADIKGIDGSTRLEAKRQRRRDGR
MAV_1728|M.avium_104                NTVVHERPPRNGKNGG--DDG-NGSSSSEIKGIDGSTRLEAKRQRRRDGR
TH_0997|M.thermoresistible__bu      NTVVHERVPRTEKEER-------DQAHSEIQGITGSTRLEAKRQRRRDGR
MAB_1607|M.abscessus_ATCC_1997      NTVVHERKPRAER-------------GDEIQGISGSTRLEAKRQRRRDGR
                                    ******* **                  :*:** ****************

Mflv_2634|M.gilvum_PYR-GCK          DAGRRRPPILSEAEFLARREAVERTMVVRDKVRTEPPHEGARYTQIAVLE
Mvan_3947|M.vanbaalenii_PYR-1       DAGRRRPPILSEAEFLARREAVERMMVIRDKVRTEPPHEGARYTQIAVLE
MSMEG_4626|M.smegmatis_MC2_155      DAGRRRPPILSEAEFLARREAVERTMIVRDKVRTEPPHEGARYTQIAVLE
MMAR_3768|M.marinum_M               DAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPHPGSRYTQIAVLE
MUL_3715|M.ulcerans_Agy99           DAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPHPGSRYTQIAVLE
Mb2471c|M.bovis_AF2122/97           DAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPLPGTRYTQIAVLE
Rv2444c|M.tuberculosis_H37Rv        DAGRRRPPVLSEAEFLARREAVERVMVVRDRVRTEPPLPGTRYTQIAVLE
MLBr_01468|M.leprae_Br4923          DAGRRRSSVLSEAEFLARRESVERVMVVRDRIRTEPPHPGARYTQIAVLE
MAV_1728|M.avium_104                DAGRRRPPVLTEAEFLARREAVERVMVVRDRIRTEPPHQGSRYTQIAVLE
TH_0997|M.thermoresistible__bu      DAGRRRPPILSEAEFLARREAVERVMVVRDKVRTEPPHQGARYTQIAVLE
MAB_1607|M.abscessus_ATCC_1997      DAGRRRPPILTEAEFLARREAVDRVMVVRDKTRSEPPHEGARYTQIAVLE
                                    ******..:*:*********:*:* *::**: *:***  *:*********

Mflv_2634|M.gilvum_PYR-GCK          DGVVVEHFVTSAAQVSLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
Mvan_3947|M.vanbaalenii_PYR-1       DGVVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MSMEG_4626|M.smegmatis_MC2_155      DGVVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MMAR_3768|M.marinum_M               DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MUL_3715|M.ulcerans_Agy99           DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
Mb2471c|M.bovis_AF2122/97           DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
Rv2444c|M.tuberculosis_H37Rv        DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MLBr_01468|M.leprae_Br4923          DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MAV_1728|M.avium_104                DGIVVEHFVTSAASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
TH_0997|M.thermoresistible__bu      DGVVVEHFVTSSASASLVGNIYLGIVQNVLPSMEAAFVDIGRGRNGVLYA
MAB_1607|M.abscessus_ATCC_1997      DGVLVEHFVTSAASASLVGNIYLGVVQNVLPSMEAAFVDIGRGRNGVLYA
                                    **::*******:*..*********:*************************

Mflv_2634|M.gilvum_PYR-GCK          GEVNWEAAGLGGAQRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
Mvan_3947|M.vanbaalenii_PYR-1       GEVNWEAAGLGGAQRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
MSMEG_4626|M.smegmatis_MC2_155      GEVNWEAAGLGGQNRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
MMAR_3768|M.marinum_M               GEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDPVGHKGARLTTQVSLA
MUL_3715|M.ulcerans_Agy99           GEVNWDAAGLGGADRKIEQALKPGDYIVVQVSKDPVGHKGARLTTQVSLA
Mb2471c|M.bovis_AF2122/97           GEVNWDAAGLGGADRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
Rv2444c|M.tuberculosis_H37Rv        GEVNWDAAGLGGADRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
MLBr_01468|M.leprae_Br4923          GEVNWEAAGLGGADRKIEQALKPGDYIVVQVNKDPVGHKGARLTTQVSLA
MAV_1728|M.avium_104                GEVNWEAAGLGGSDRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQVSLA
TH_0997|M.thermoresistible__bu      GEVNWEAAGLGGQNRKIEQALKPGDYVVVQVSKDPVGHKGARLTTQLSLA
MAB_1607|M.abscessus_ATCC_1997      GEVNWDAAGLGGSNRKIEQALKSGDYVLVQVSKDPVGHKGARLTTQISLA
                                    *****:****** :********.***::***.**************:***

Mflv_2634|M.gilvum_PYR-GCK          GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSNAGVIIRTASEGV
Mvan_3947|M.vanbaalenii_PYR-1       GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
MSMEG_4626|M.smegmatis_MC2_155      GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
MMAR_3768|M.marinum_M               GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
MUL_3715|M.ulcerans_Agy99           GRYLVYVAGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
Mb2471c|M.bovis_AF2122/97           GRFLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
Rv2444c|M.tuberculosis_H37Rv        GRFLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
MLBr_01468|M.leprae_Br4923          GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPPDAGVIIRTASEGV
MAV_1728|M.avium_104                GRYLVYVPGASSTGISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGV
TH_0997|M.thermoresistible__bu      GRYLVYVPGATSTGISRKLPDTERQRLKEILREVVPPDAGVIIRTASEGV
MAB_1607|M.abscessus_ATCC_1997      GRYLVYVPGASSTGISRKLPDTERQRLKEILRDIVPADAGVIIRTASEGV
                                    **:****.**:*********************::**.:************

Mflv_2634|M.gilvum_PYR-GCK          KEDDIRTDVERLQKRWTDIEAKAAEVTAKKAGAAVALYEEPDVLVKVIRD
Mvan_3947|M.vanbaalenii_PYR-1       KEEDIRSDVERLQKRWTEIEAKAAEITEKKAGAAVALYEEPDVLVKVIRD
MSMEG_4626|M.smegmatis_MC2_155      KEEDIRSDVERLQKRWSEIEAKAAEVTEKKAGAAVALYEEPDVLVKVIRD
MMAR_3768|M.marinum_M               KEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALYEEPDVLVKVIRD
MUL_3715|M.ulcerans_Agy99           KEDDIRADVTRLQERWNQIEAKAVEIKQKAAGAAVALYEEPDVLVKVIRD
Mb2471c|M.bovis_AF2122/97           KEDDIRADVARLRERWEQIEAKAQETKEKAAGAAVALYEEPDVLVKVIRD
Rv2444c|M.tuberculosis_H37Rv        KEDDIRADVARLRERWEQIEAKAQETKEKAAGAAVALYEEPDVLVKVIRD
MLBr_01468|M.leprae_Br4923          KEEDIRKDVTRLQEHWEQIEAKTIQTKEKAAGAAVALYEEPDVLVKVIRD
MAV_1728|M.avium_104                KEDDIRGDVTRLQERWKQIEAKAIEIKEKAAGAAVALYEEPDVLVKVIRD
TH_0997|M.thermoresistible__bu      KEEDIRADVNRLQERWTQIEAKAAELTEKKAGQAVALYEEPDVLVKVIRD
MAB_1607|M.abscessus_ATCC_1997      REEDIRADVQRLQEQWQGIEQSATDLTSKASGAAVALYEEPDVLVKVVRD
                                    :*:*** ** **:::*  ** .: : . * :* **************:**

Mflv_2634|M.gilvum_PYR-GCK          LFNEDFSNLIVSGDQAWKTIDDYVTAVAPELLPRITRYEPAGSPEAGTAP
Mvan_3947|M.vanbaalenii_PYR-1       LFNEDFTGLTVSGDHAWKTINDYVTAVAPELLPRMTQYEPASP----DAP
MSMEG_4626|M.smegmatis_MC2_155      LFNEDFSSLIVSGDEAWNTINSYVEAVAPDLMPRLTKYEPAGP----DAP
MMAR_3768|M.marinum_M               LFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKYEPAVGSEGQVGP
MUL_3715|M.ulcerans_Agy99           LFNEDFAGLVVSGDDAWDTINEYVSSVAPDLVSKLSKYEPAVGSEGQVGP
Mb2471c|M.bovis_AF2122/97           LFNEDFVGLIVSGDEAWNTINEYVNSVAPELVSKLTKYESADGPDGQSAP
Rv2444c|M.tuberculosis_H37Rv        LFNEDFVGLIVSGDEAWNTINEYVNSVAPELVSKLTKYESADGPDGQSAP
MLBr_01468|M.leprae_Br4923          LFNDDFSGLVVSGDEAWNTINEYVNSVAPELVSKLTKYDPPIGPDGQHGP
MAV_1728|M.avium_104                LFNEDFAGLIVSGDDAWNTINEYVNSVAPDLVSKVTKYEPATGPDGTPGP
TH_0997|M.thermoresistible__bu      LFNEDFSRLIVSGDHAWNTINEYVSTVAPDLMPRLTKYEPAS----EDGP
MAB_1607|M.abscessus_ATCC_1997      LFNEDFSKLIIEGDAAWDTIDDYVKTVAPDLLSRIERYESGE------GP
                                    ***:**  * :.** **.**:.** :***:*:.:: :*:.        .*

Mflv_2634|M.gilvum_PYR-GCK          DVFAVHRIDEQLAKAMDRKVYLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
Mvan_3947|M.vanbaalenii_PYR-1       DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
MSMEG_4626|M.smegmatis_MC2_155      DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
MMAR_3768|M.marinum_M               DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
MUL_3715|M.ulcerans_Agy99           DVFAVHRIDEHLAKAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSG
Mb2471c|M.bovis_AF2122/97           DVFTVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGAG
Rv2444c|M.tuberculosis_H37Rv        DVFTVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGAG
MLBr_01468|M.leprae_Br4923          DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSG
MAV_1728|M.avium_104                DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSG
TH_0997|M.thermoresistible__bu      DVFAVHRIDEQLAKAMDRKVWLPSGGTLVIDRTEAMTVIDVNTGKFTGSG
MAB_1607|M.abscessus_ATCC_1997      DVFAVHRIDEQLAKALDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGAG
                                    ***:******:****:****:*****************:*********:*

Mflv_2634|M.gilvum_PYR-GCK          GNLEQTVTRNNLEAAEETVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
Mvan_3947|M.vanbaalenii_PYR-1       GNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MSMEG_4626|M.smegmatis_MC2_155      GNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MMAR_3768|M.marinum_M               GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MUL_3715|M.ulcerans_Agy99           GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
Mb2471c|M.bovis_AF2122/97           GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
Rv2444c|M.tuberculosis_H37Rv        GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MLBr_01468|M.leprae_Br4923          GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MAV_1728|M.avium_104                GNLEQTVTKNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
TH_0997|M.thermoresistible__bu      GNLEQTVTRNNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRR
MAB_1607|M.abscessus_ATCC_1997      GNLEETVTRNNLEAAEEIVRQLRLRDVGGIVVIDFIDMVLESNRDLVLRR
                                    ****:***:******** ********:***********************

Mflv_2634|M.gilvum_PYR-GCK          LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTTCTHCSGRGI
Mvan_3947|M.vanbaalenii_PYR-1       LTEALARDRTRHQVSEVTSLGLVQLTRKKLGTGLIEAFSTTCSHCAGRGI
MSMEG_4626|M.smegmatis_MC2_155      LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTACTHCGGRGI
MMAR_3768|M.marinum_M               LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTSCPHCSGRGI
MUL_3715|M.ulcerans_Agy99           LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPHCSGRGI
Mb2471c|M.bovis_AF2122/97           LTESLARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPNCSGRGI
Rv2444c|M.tuberculosis_H37Rv        LTESLARDRTRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPNCSGRGI
MLBr_01468|M.leprae_Br4923          LTEVLARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTSCPNCTGRGI
MAV_1728|M.avium_104                LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLVEAFSTSCPNCGGRGI
TH_0997|M.thermoresistible__bu      LTEALARDRTRHQVSEVTSLGLVQLTRKRLGTGLLEAFSTTCTHCNGRGI
MAB_1607|M.abscessus_ATCC_1997      LTEALGRDRTRHQVSEVTSLGLVQLTRKKLGTGLIEAFSSTCTHCAGRGI
                                    *** *.**********************:*****:****::*.:* ****

Mflv_2634|M.gilvum_PYR-GCK          MLHGDPVDSS--SGSNGRKADSGGGGNGGGGGGGGRRSRRGKRGAKPEP-
Mvan_3947|M.vanbaalenii_PYR-1       MLHGDPVDSM--APANGRKSEPG----------TGRRSKRGKRGARAEQ-
MSMEG_4626|M.smegmatis_MC2_155      VLHGDPIDSA--SSNGGRKSDSSG----GGGSGGGRRGKRGKKGAARTE-
MMAR_3768|M.marinum_M               LLHADPVDS---APTTGRKADSG-----------GRRNRRSKKNRAEEPS
MUL_3715|M.ulcerans_Agy99           LLHADPVDS---APTTGRKADSG-----------GRRNRRSKKNRAEEPS
Mb2471c|M.bovis_AF2122/97           LLHADPVDS---AAATGRKSEPG-----------ARRGKRSKKSRSEESS
Rv2444c|M.tuberculosis_H37Rv        LLHADPVDS---AAATGRKSEPG-----------ARRGKRSKKSRSEESS
MLBr_01468|M.leprae_Br4923          LLHTDPANS---TPMVGRKSESG-----------GRRSKRSKKNRSDE--
MAV_1728|M.avium_104                LLHADPVDS---APSNGRKSESG-----------GRRGRR-KKSKAEEP-
TH_0997|M.thermoresistible__bu      VLHTDPVDS---AQPS-RRSDSG-----------SRRSKRSKRSRSDD--
MAB_1607|M.abscessus_ATCC_1997      VLHVDPVDNASNASSPAKKAETG------------RRAKRSRKGKTDD--
                                    :** ** :.   :    ::::..            ** :* ::.      

Mflv_2634|M.gilvum_PYR-GCK          -EVQVTKVPAHLPGEHPMFKAMAAANGKDE------DGEDGQDGEERDDV
Mvan_3947|M.vanbaalenii_PYR-1       -EVPVVKVPSHSPGEHPMFKAMAAANGKHE------DDDS---EHEDDGT
MSMEG_4626|M.smegmatis_MC2_155      -EVHVAKVPDHTPGEHPMFKAMAAANGKHEGDEDHEDHEDHETAEDTTAA
MMAR_3768|M.marinum_M               EKEAVAKVPTHAPGEHPMFKAMAASSS-----SEAEHGDGE---VEESGE
MUL_3715|M.ulcerans_Agy99           EKEAVAKVPTYAPGEHPMFKAMAASSS-----SEAEHGDGE---VEESGE
Mb2471c|M.bovis_AF2122/97           DRSMVAKVPVHAPGEHPMFKAMAAGLS-----SLAGRGDEE---SGEPAA
Rv2444c|M.tuberculosis_H37Rv        DRSMVAKVPVHAPGEHPMFKAMAAGLS-----SLAGRGDEE---SGEPAA
MLBr_01468|M.leprae_Br4923          --TAVVKVPVHAPGEHPMFKAMAAGSS-----SVVVGGEDE---SNESGT
MAV_1728|M.avium_104                ---VVAKVPVHSPGEHPMFKAMAAGSS-----TQAASDEDESA-AEEAGD
TH_0997|M.thermoresistible__bu      --VQVVKVPPHPPGEHPLFKAMAAASERAD--SEAKDDTEETGDGGKDAA
MAB_1607|M.abscessus_ATCC_1997      --VVVARTPSHPQGEHPMFKAMAAANG-------HHEDDED---ADVNED
                                        *.:.* :  ****:******.                         

Mflv_2634|M.gilvum_PYR-GCK          SLAPEEVAEIDADATPTVADTDD---------------------------
Mvan_3947|M.vanbaalenii_PYR-1       AVPPEEVAELDADATRAVTDSD----------------------------
MSMEG_4626|M.smegmatis_MC2_155      EVRDDTRDEHDADERAHVVTAAVG--------------------------
MMAR_3768|M.marinum_M               ELTAAVDDQTAVQVALDLGQTD----------------------------
MUL_3715|M.ulcerans_Agy99           ELTAAVDDQTAVQVALDLG-------------------------------
Mb2471c|M.bovis_AF2122/97           ELA----EQAGDQPPTDLD-------------------------------
Rv2444c|M.tuberculosis_H37Rv        ELA----EQAGDQPPTDLD-------------------------------
MLBr_01468|M.leprae_Br4923          ELTGKIDEPLEEQAVAGLD-------------------------------
MAV_1728|M.avium_104                ELERKKAARAEELEAAEDT-------------------------------
TH_0997|M.thermoresistible__bu      KVAAKVKEKVAAEDRAKVGAQDGVEEATPDGVETEAAAATRAERVRTAVS
MAB_1607|M.abscessus_ATCC_1997      ALDDDALEEVEEVEEIVET-------------------------------
                                     :                                                

Mflv_2634|M.gilvum_PYR-GCK          -------------EFGDDSEDDDSEDDDSEDDDSEDDDSDVDEIDLDDDD
Mvan_3947|M.vanbaalenii_PYR-1       ----------------DDDLDDDFDDEDADDEDTDDED----EIDLDDDD
MSMEG_4626|M.smegmatis_MC2_155      -------------AAGDEDLDDSDEDSDLDSDEESDDESDEDEIELDDDE
MMAR_3768|M.marinum_M               ---ETEETDETDETDETDDFDDDSDDSDDSDEDDDSDETNDTDVDAGEDE
MUL_3715|M.ulcerans_Agy99           ---ETEESEETDGTDETDDFDDDSDDSDDSDEDDDTDETNDTDVDADEDE
Mb2471c|M.bovis_AF2122/97           -------------DTAQADFEDTEDTDEDEDE-----------LDADEDL
Rv2444c|M.tuberculosis_H37Rv        -------------DTAQADFEDTEDTDEDEDE-----------LDADEDL
MLBr_01468|M.leprae_Br4923          -------------DVDQEDFDTDEEDDLDDDEE----------LDDEEDL
MAV_1728|M.avium_104                --------------EDLEDTEDDDEDSDDSDD------------SDDEDL
TH_0997|M.thermoresistible__bu      GDAQASAGDLDDEDLANGDLEDEYLDDEDEDEDLEDGDLENGDLDDEDDD
MAB_1607|M.abscessus_ATCC_1997      --------------IQSAETPDNVPDQD----------------EPEHEP
                                                      .       .                 .  .: 

Mflv_2634|M.gilvum_PYR-GCK          EDEDDD----IDELDDDEDSDDED--------------------EDDDED
Mvan_3947|M.vanbaalenii_PYR-1       DEADDD----IEELDD-EDSDDEE--------------------TDEDSD
MSMEG_4626|M.smegmatis_MC2_155      DELDED----IEVIGDSDDSDDSDD-----------------SDEDDDSD
MMAR_3768|M.marinum_M               DTDDDSDEDSDDDSDEDEDTEDDELDDDLDEDDLDDDLDEDDDDLDDELD
MUL_3715|M.ulcerans_Agy99           DTDDDS--------DEDEDTEDD---------------DELDDDLDDELD
Mb2471c|M.bovis_AF2122/97           EDLDDE------DLDEDLDVEDS-----------------DSDDEDSDED
Rv2444c|M.tuberculosis_H37Rv        EDLDDE------DLDEDLDVEDS-----------------DSDDEDSDED
MLBr_01468|M.leprae_Br4923          GDDDEEL-----DLDDDLDVDE--------------------DESDSEAD
MAV_1728|M.avium_104                DDEDIDDEEDLGDDDEDLELDD--------------------DDLDTEDS
TH_0997|M.thermoresistible__bu      EDLEDGE----IDVDLDEDLDDDIEVLN-----------GDPDDEEADED
MAB_1607|M.abscessus_ATCC_1997      ASAGSN--------AASEPWAEG--------------------APEAAAT
                                                         :                       :    

Mflv_2634|M.gilvum_PYR-GCK          DD---------SDFDDDDEDEDSDEDDEEE-----PVAAAPVGRHRRRAA
Mvan_3947|M.vanbaalenii_PYR-1       D--------------EDTDGEDSDEEEEPV-----AVAVRP-GRQRRRAA
MSMEG_4626|M.smegmatis_MC2_155      DS---------DDDSDEDEDSDSDEDEEPVREVYEPPVTAPRARVRRRAA
MMAR_3768|M.marinum_M               DD--------DSDSD-DEDGESELTEPAAGRPAALEVTTIAERPRRRRAA
MUL_3715|M.ulcerans_Agy99           DD--------DSDSD-DEDSESELTEPAAGRPAALEVTTIAERPRRRRAA
Mb2471c|M.bovis_AF2122/97           AA--------DADVD-EED--AAGLDGSPGEVDVPGVTELAPTRPRRRVA
Rv2444c|M.tuberculosis_H37Rv        AA--------DADVD-EED--AAGLDGSPGEVDVPGVTELAPTRPRRRVA
MLBr_01468|M.leprae_Br4923          LD--------SADVL-DRS--TLLIRNRSG---------FARPR-RRRAA
MAV_1728|M.avium_104                DD--------SDDSD-DSEDSDDSEDQRDPAAECPGVSALGRPR-RRRAA
TH_0997|M.thermoresistible__bu      VDSYEDPYDADADADSDSDADADDEDSGDDRAAGRYAAPTVTRRPRRRAA
MAB_1607|M.abscessus_ATCC_1997      EP--------------------GTAEPEAPAATPEPAAAAPTRPRRRRSA
                                                                                 *** *

Mflv_2634|M.gilvum_PYR-GCK          ARPAGPPIRD-
Mvan_3947|M.vanbaalenii_PYR-1       ARPAGPPSQD-
MSMEG_4626|M.smegmatis_MC2_155      ARPAGPPSHD-
MMAR_3768|M.marinum_M               GRPAGPPIHLG
MUL_3715|M.ulcerans_Agy99           GRPAGPPIHLG
Mb2471c|M.bovis_AF2122/97           GRPAGPPIRLD
Rv2444c|M.tuberculosis_H37Rv        GRPAGPPIRLD
MLBr_01468|M.leprae_Br4923          GRPAGPPIHVD
MAV_1728|M.avium_104                GRPAGPPIHAD
TH_0997|M.thermoresistible__bu      VRPAGPPVQS-
MAB_1607|M.abscessus_ATCC_1997      ARAAGPPVEH-
                                     *.**** .