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MTVVLIDPHYLLVPMEALEVLRQQVQYTEEIPAALTRLLPAARPVRAGSHATVLLSSDPTHPAVTARLVA GDRLISIPHPQCGERLIDAVAAVDELRTAGSWEAAQTHVSVSRYLLSQTYALLDAPRSADAGQLREELGA LLLQVLFQARIAQDAPRRPFAIDDVADTLIRKLGNRRRGVLAGNSPSFQEQVAQWEKGKKADKRAGSVMH DLFHGQPALALAQKVIERAVRAGLPMDLVPATLTSVVVSPDIDSEGELRAAVLEFMDSVRRAEDTIAARR RAPDATEEPDRTALGGITEREWRMCWPSVGAHTQSGVRVANPRDDA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3470 | - | - | 100% (326) | nucleoside triphosphate pyrophosphohydrolase |
| M. ulcerans Agy99 | MUL_4633 | - | 5e-97 | 61.27% (315) | nucleoside triphosphate pyrophosphohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1049 | - | 1e-98 | 60.25% (317) | nucleoside triphosphate pyrophosphohydrolase |
| M. gilvum PYR-GCK | Mflv_1949 | - | 3e-90 | 56.15% (317) | nucleoside triphosphate pyrophosphohydrolase |
| M. tuberculosis H37Rv | Rv1021 | - | 1e-98 | 60.25% (317) | nucleoside triphosphate pyrophosphohydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1158 | - | 7e-81 | 53.21% (312) | nucleoside triphosphate pyrophosphohydrolase |
| M. marinum M | MMAR_1560 | - | 0.0 | 98.77% (326) | hypothetical protein MMAR_1560 |
| M. avium 104 | MAV_1162 | - | 2e-91 | 58.71% (310) | nucleoside triphosphate pyrophosphohydrolase |
| M. smegmatis MC2 155 | MSMEG_5422 | - | 1e-97 | 58.54% (328) | nucleoside triphosphate pyrophosphohydrolase |
| M. thermoresistible (build 8) | TH_0915 | - | 4e-94 | 58.81% (318) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_4776 | - | 4e-89 | 56.41% (312) | nucleoside triphosphate pyrophosphohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5422|M.smegmatis_MC2_155 MIVVLVDPRRPALVPVDAVEFLTGDVQYTEEMPVKVPWSLPSARPAYDGE
TH_0915|M.thermoresistible__bu MTVVLVDPRRPSLVPVEAVGLLAGDVQYTEEMPVKVPWSLPSARPWMADS
Mflv_1949|M.gilvum_PYR-GCK MTVVLVDPRRPSLVPVEAIELLSGDVQYTEEMPIKVPWSLPAARPAHTG-
Mvan_4776|M.vanbaalenii_PYR-1 MTVVLVDPRRPSLIPIEAIELLTGDVQYTEEMPIKVPWSLPSARPCLAGS
Mb1049|M.bovis_AF2122/97 MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAARSAHAG-
Rv1021|M.tuberculosis_H37Rv MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAARSAHAG-
MAV_1162|M.avium_104 MIVILCDPRRPSLVPVEAVEHLTGEVQYTEEMPIAVPWSLPAARPVHSGD
MAB_1158|M.abscessus_ATCC_1997 MTVILVDPRHPSMVPVEAVALLAGDLQYTEELPVRLAWSLSTARPVYIG-
MUL_3470|M.ulcerans_Agy99 MTVVLIDP-HYLLVPMEALEVLRQQVQYTEEIPAALTRLLPAARPVRAG-
MMAR_1560|M.marinum_M MTVVLIDP-HYLLVPMEALEVLRQQVQYTEEIPAALTRLLPAARPVRAG-
* *:* ** : ::*::*: * ::*****:* :. *.:**. .
MSMEG_5422|M.smegmatis_MC2_155 D---APVLLSSDPEHPVVKARLAAGDRLIAAPEPQPGERLVDAVALMDKL
TH_0915|M.thermoresistible__bu DDDPAPVLLSSDPDHPAVQDRLAAGEQLIRAPEPYPGERLLDAVAMMDQL
Mflv_1949|M.gilvum_PYR-GCK --DPAEVLLSSDARHPAVVARVAAGERVIAAPAAQSGERLVDAVAMMDRL
Mvan_4776|M.vanbaalenii_PYR-1 DDEPAAVLLSSDPGHPSVAARIAAGERVICAPAPQPGERLVDAVAMMDKL
Mb1049|M.bovis_AF2122/97 --NDAPVLLSSDPNHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKL
Rv1021|M.tuberculosis_H37Rv --NDAPVLLSSDPNHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKL
MAV_1162|M.avium_104 PDDPAPVLLSSDRDHPAVTARLAAGARLISAPDAPRGERLVDAVAMMDKL
MAB_1158|M.abscessus_ATCC_1997 --EDAPALLSSDPDHPEVRARVKAGAAVIAPPARQ-GEKLIDAVAVMDRL
MUL_3470|M.ulcerans_Agy99 --SHATVLLSSDPTHPAVTARLVAGDRLISIPHPQCGERLIDAVAAVDEL
MMAR_1560|M.marinum_M --SHATVLLSSDPTHPAVTARLVAGDRLISIPHPQCGERLIDAVAAVDEL
* .***** ** * *: ** :* * **:*:**** :*.*
MSMEG_5422|M.smegmatis_MC2_155 RTSGPWESEQTHDSLRRYLLEETYELFDAVRSGNADELREELGDVLLQVL
TH_0915|M.thermoresistible__bu RTSGPWESEQTHDSLRRYLLEETYELFDAVRSGNADELREELGDVLLQVL
Mflv_1949|M.gilvum_PYR-GCK RTAGPWESQQTHDSLRRYLLEETYELFDAVHGGDLTELRDELGDVLLQVL
Mvan_4776|M.vanbaalenii_PYR-1 RTAGPWESQQTHDSLRRYLLEETYELFDAVHGGDLTELRDELGDVLLQVL
Mb1049|M.bovis_AF2122/97 RTAGPWESEQTHDSLRRYLLEETYELLDAVRSGSVDQLREELGDLLLQVL
Rv1021|M.tuberculosis_H37Rv RTAGPWESEQTHDSLRRYLLEETYELLDAVRSGSVDQLREELGDLLLQVL
MAV_1162|M.avium_104 RTAGPWESEQTHESLRRFLLEETYELLDAVAGGNAEALRDELGDVLLQVL
MAB_1158|M.abscessus_ATCC_1997 RTNGPWESTQTHDSLRRYLLEETYELFDAVRTGDADELREELGDVLLQVL
MUL_3470|M.ulcerans_Agy99 RTAGSWEAAQTHVSVSRYLLSQTYALLDAPRSADAGQLREELGALLLQVL
MMAR_1560|M.marinum_M RTAGSWEAAQTHVSVSRYLLSQTYALLDALRSADAGQLREELGALLLQVL
** *.**: *** *: *:**.:** *:** .. **:*** :*****
MSMEG_5422|M.smegmatis_MC2_155 FHARIAEDAPHHPFSIDDVADALVRKLGNRVPAVLAG----ESISLDEQL
TH_0915|M.thermoresistible__bu FHARIAEDAPENPFSIDDVADALVRKLGNRVPAVLAG----EPVTLDEQL
Mflv_1949|M.gilvum_PYR-GCK FHARIAEEAPENGFGIDDVADALVRKLGNRVPAVLAG----ESISLEDQL
Mvan_4776|M.vanbaalenii_PYR-1 FHARIAEEAPHNSFDVDDVADALVRKLGNRVPAVLAG----ESISLEDQL
Mb1049|M.bovis_AF2122/97 FHARIAEDASQSPFTIDDVADTLMRKLGNRAPGVLAG----ESISLEDQL
Rv1021|M.tuberculosis_H37Rv FHARIAEDASQSPFTIDDVADTLMRKLGNRAPGVLAG----ESISLEDQL
MAV_1162|M.avium_104 FHARIAEDAPQSAFTIDDVAAALIRKLGNRVPGVLAG----QTISLEEQL
MAB_1158|M.abscessus_ATCC_1997 FHARIAEDAPEHPFNIDDVAETLLSKLGNRIPVLLGAGGDSASISLEEQL
MUL_3470|M.ulcerans_Agy99 FQARIAQDAPRRPFAIDDVADTLIRKLGNRRRGVLAG----NSPSFQEQV
MMAR_1560|M.marinum_M FQARIAQDAPRRPFTIDDVADTLIRKLGNRRRGVLAG----NSPSFQEQV
*:****::*.. * :**** :*: ***** :*.. . ::::*:
MSMEG_5422|M.smegmatis_MC2_155 AQWEERKAQEKKVKARASSMDDVPTGQPALALAQKVLARVSQAGLPAELI
TH_0915|M.thermoresistible__bu AQWEERKALERRSKRNRSCLDDVPTGQPALALAQKVIERVTQAGLPADLI
Mflv_1949|M.gilvum_PYR-GCK AQWEQRKALERSTRR--SSMDDIPTAQPALALAQKVLARAETAGVPVDLI
Mvan_4776|M.vanbaalenii_PYR-1 AQWEQRKALERSTRE--SIMDDIPTAQPALALAQKVLARAETGGVPHDLI
Mb1049|M.bovis_AF2122/97 AQWEAAKASEKARKS---VADDVHTGQPALALAQKVIQRAQKAGLPAHLI
Rv1021|M.tuberculosis_H37Rv AQWEAAKASEKARKS---VADDVHTGQPALALAQKVIQRAQKAGLPAHLI
MAV_1162|M.avium_104 AQWEERKAAEKPRKS---VMDDVHTGQPALALAQKVIGRAEKAGLPADLI
MAB_1158|M.abscessus_ATCC_1997 AQWEERKAEEKKDRD--SCLDGISSSQPALALTQKVLGRVTAAGLPAELI
MUL_3470|M.ulcerans_Agy99 AQWEKGKKADKRAGS---VMHDLFHGQPALALAQKVIERAVRAGLPMDLV
MMAR_1560|M.marinum_M AQWEKGKKADKRAGS---VMHDLFHGQPALALAQKVIERAVRAGLPMDLV
**** * :: ..: .******:***: *. .*:* .*:
MSMEG_5422|M.smegmatis_MC2_155 PASLTSVSVSADTDSENELRTAVLEFMDTVREVEAAVAAGRRGEDVPEEL
TH_0915|M.thermoresistible__bu PSTITSVAVSAGSDAEHVLRTHVLEFMDTVRRVEEAVAAVRRGEDVPEEL
Mflv_1949|M.gilvum_PYR-GCK PDAVTKVTVTADFDAENALRTAVLEFMADVRVAERAAGAARRGADVAEEL
Mvan_4776|M.vanbaalenii_PYR-1 PAAITSVAVSADIDAENALRSAVLEFMADVRDAERAATAARRGADVAEEL
Mb1049|M.bovis_AF2122/97 PDEITSVSVSADVDAENTLRTAVLDFIDRLRCAERAIAVARRGSNVAEQL
Rv1021|M.tuberculosis_H37Rv PDEITSVSVSADVDAENTLRTAVLDFIDRLRCAERAIAVARRGSNVAEQL
MAV_1162|M.avium_104 PPQVTSIAISADVDAESALRTAVLDFVATVRGVERSIAAARRGTSVPDEF
MAB_1158|M.abscessus_ATCC_1997 PAQLLSVRIDPDGDAENQLRADALEFMDTVRRAEKDILRGRRGDDVASEL
MUL_3470|M.ulcerans_Agy99 PATLTSVVVSPDIDSEGELRAAVLEFMDSVRRAEDTIAARRRAPDATEEP
MMAR_1560|M.marinum_M PATLTSVVVSPDIDAEGELRAAVLEFMDSVRRAEDTIAARRRAPDATEEP
* : .: : .. *:* **: .*:*: :* .* **. ....:
MSMEG_5422|M.smegmatis_MC2_155 DVAPLGVISEDEWRAYWP-------------------GAESSAS-----E
TH_0915|M.thermoresistible__bu DVAPLDDITEEEWRTYWPTVSAAEAGTVAEVDAETVSGAESDAEPAHSGD
Mflv_1949|M.gilvum_PYR-GCK DDAPRGGITEDEWRAAWPR------------------EIAESAS------
Mvan_4776|M.vanbaalenii_PYR-1 DDAPHGVISADEWRAHWPG------------------ADEPVAE------
Mb1049|M.bovis_AF2122/97 DVTPLGVITEQEWLAHWPT------------------AVNDSRG------
Rv1021|M.tuberculosis_H37Rv DVTPLGVITEQEWLAHWPT------------------AVNDSRG------
MAV_1162|M.avium_104 DIAPLGEISEQEWRQHWPA------------------GDTDPEP------
MAB_1158|M.abscessus_ATCC_1997 DVSDLREVSTEEWRAHWRQAP--------------ADPAAATETDLTAEE
MUL_3470|M.ulcerans_Agy99 DRTALGGITEREWRMCWPS------------------VGAHTQS------
MMAR_1560|M.marinum_M DRTALGGITEREWRMCWPS------------------VGAHTQS------
* : :: ** *
MSMEG_5422|M.smegmatis_MC2_155 AEPEE---------------
TH_0915|M.thermoresistible__bu GEPGDGEPGDGAAADEP---
Mflv_1949|M.gilvum_PYR-GCK -EPA----------------
Mvan_4776|M.vanbaalenii_PYR-1 -EPDAAEG------------
Mb1049|M.bovis_AF2122/97 -GSKKRKGMR----------
Rv1021|M.tuberculosis_H37Rv -GSKKRKGMR----------
MAV_1162|M.avium_104 -APAEQLTDDAGGDEN----
MAB_1158|M.abscessus_ATCC_1997 QQPDVHDDEEAADSGRPKSA
MUL_3470|M.ulcerans_Agy99 -GVRVANPRDDA--------
MMAR_1560|M.marinum_M -GVRVAKPRDDA--------