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M. thermoresistible (build 8) TH_0915 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1831012 - 1832103
length: 364

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0915-100% (364)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1049-1e-12070.16% (315) nucleoside triphosphate pyrophosphohydrolase
M. gilvum PYR-GCKMflv_1949-1e-12470.46% (325) nucleoside triphosphate pyrophosphohydrolase
M. tuberculosis H37RvRv1021-1e-12070.16% (315) nucleoside triphosphate pyrophosphohydrolase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1158-1e-11359.50% (358) nucleoside triphosphate pyrophosphohydrolase
M. marinum MMMAR_4464-1e-12466.20% (355) hypothetical protein MMAR_4464
M. avium 104MAV_1162-1e-12467.16% (335) nucleoside triphosphate pyrophosphohydrolase
M. smegmatis MC2 155MSMEG_5422-1e-14279.57% (323) nucleoside triphosphate pyrophosphohydrolase
M. ulcerans Agy99MUL_4633-1e-12466.20% (355) nucleoside triphosphate pyrophosphohydrolase
M. vanbaalenii PYR-1Mvan_4776-1e-12870.21% (329) nucleoside triphosphate pyrophosphohydrolase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0915|M.thermoresistible__bu      MTVVLVDPRRPSLVPVEAVGLLAGDVQYTEEMPVKVPWSLPSARPWMADS
MSMEG_5422|M.smegmatis_MC2_155      MIVVLVDPRRPALVPVDAVEFLTGDVQYTEEMPVKVPWSLPSARPAYDGE
Mb1049|M.bovis_AF2122/97            MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAARSAHAG-
Rv1021|M.tuberculosis_H37Rv         MIVVLVDPRRPTLVPVEAIEFLRGEVQYTEEMPVAVPWSLPAARSAHAG-
MMAR_4464|M.marinum_M               MIVVLVDPRRPSLVPVEAIELLGGTVQYTEEMPIAVPWSLPDAHPVHVG-
MUL_4633|M.ulcerans_Agy99           MIVVLVDPRRPSLVPVEAIELLGGTVQYTEEMPIAVPWSLPDAYPVHVG-
MAV_1162|M.avium_104                MIVILCDPRRPSLVPVEAVEHLTGEVQYTEEMPIAVPWSLPAARPVHSGD
Mflv_1949|M.gilvum_PYR-GCK          MTVVLVDPRRPSLVPVEAIELLSGDVQYTEEMPIKVPWSLPAARPAHTG-
Mvan_4776|M.vanbaalenii_PYR-1       MTVVLVDPRRPSLIPIEAIELLTGDVQYTEEMPIKVPWSLPSARPCLAGS
MAB_1158|M.abscessus_ATCC_1997      MTVILVDPRHPSMVPVEAVALLAGDLQYTEELPVRLAWSLSTARPVYIG-
                                    * *:* ***:*:::*::*:  * * :*****:*: :.***. * .   . 

TH_0915|M.thermoresistible__bu      DDDPAPVLLSSDPDHPAVQDRLAAGEQLIRAPEPYPGERLLDAVAMMDQL
MSMEG_5422|M.smegmatis_MC2_155      D---APVLLSSDPEHPVVKARLAAGDRLIAAPEPQPGERLVDAVALMDKL
Mb1049|M.bovis_AF2122/97            --NDAPVLLSSDPNHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKL
Rv1021|M.tuberculosis_H37Rv         --NDAPVLLSSDPNHPAVITRLAAGARLISAPDSQRGERLVDAVAMMDKL
MMAR_4464|M.marinum_M               --EEAPVLLSSDPNHPAVVARLAAGARLIAAPDRRRGERLLDAVAMMDKL
MUL_4633|M.ulcerans_Agy99           --EEAPVLLSSDPNHPAVVARLAAGVRLIAAPDRRRGERLLDAVAMMDKL
MAV_1162|M.avium_104                PDDPAPVLLSSDRDHPAVTARLAAGARLISAPDAPRGERLVDAVAMMDKL
Mflv_1949|M.gilvum_PYR-GCK          --DPAEVLLSSDARHPAVVARVAAGERVIAAPAAQSGERLVDAVAMMDRL
Mvan_4776|M.vanbaalenii_PYR-1       DDEPAAVLLSSDPGHPSVAARIAAGERVICAPAPQPGERLVDAVAMMDKL
MAB_1158|M.abscessus_ATCC_1997      --EDAPALLSSDPDHPEVRARVKAGAAVIAPPARQ-GEKLIDAVAVMDRL
                                        * .*****  ** *  *: **  :* .*    **:*:****:**:*

TH_0915|M.thermoresistible__bu      RTSGPWESEQTHDSLRRYLLEETYELFDAVRSGNADELREELGDVLLQVL
MSMEG_5422|M.smegmatis_MC2_155      RTSGPWESEQTHDSLRRYLLEETYELFDAVRSGNADELREELGDVLLQVL
Mb1049|M.bovis_AF2122/97            RTAGPWESEQTHDSLRRYLLEETYELLDAVRSGSVDQLREELGDLLLQVL
Rv1021|M.tuberculosis_H37Rv         RTAGPWESEQTHDSLRRYLLEETYELLDAVRSGSVDQLREELGDLLLQVL
MMAR_4464|M.marinum_M               RTDGPWESEQTHDSLRRYLLEETYELLDAVHSGSVDQLREELGDLLLQVL
MUL_4633|M.ulcerans_Agy99           RTDGPWESEQTHDSLRRYLLEETYELLDAVHSGSVDQLREELGDLLLQVL
MAV_1162|M.avium_104                RTAGPWESEQTHESLRRFLLEETYELLDAVAGGNAEALRDELGDVLLQVL
Mflv_1949|M.gilvum_PYR-GCK          RTAGPWESQQTHDSLRRYLLEETYELFDAVHGGDLTELRDELGDVLLQVL
Mvan_4776|M.vanbaalenii_PYR-1       RTAGPWESQQTHDSLRRYLLEETYELFDAVHGGDLTELRDELGDVLLQVL
MAB_1158|M.abscessus_ATCC_1997      RTNGPWESTQTHDSLRRYLLEETYELFDAVRTGDADELREELGDVLLQVL
                                    ** ***** ***:****:********:***  *.   **:****:*****

TH_0915|M.thermoresistible__bu      FHARIAEDAPENPFSIDDVADALVRKLGNRVPAVLAG----EPVTLDEQL
MSMEG_5422|M.smegmatis_MC2_155      FHARIAEDAPHHPFSIDDVADALVRKLGNRVPAVLAG----ESISLDEQL
Mb1049|M.bovis_AF2122/97            FHARIAEDASQSPFTIDDVADTLMRKLGNRAPGVLAG----ESISLEDQL
Rv1021|M.tuberculosis_H37Rv         FHARIAEDASQSPFTIDDVADTLMRKLGNRAPGVLAG----ESISLEDQL
MMAR_4464|M.marinum_M               FHARIAEDAALLPFTIDDVADTLMRKLGNRAPGVLAG----ESISLQEQM
MUL_4633|M.ulcerans_Agy99           FHARIAEDAALLPFTIDDVADTLMRKLGNRAPGVLAG----ESISLQEQI
MAV_1162|M.avium_104                FHARIAEDAPQSAFTIDDVAAALIRKLGNRVPGVLAG----QTISLEEQL
Mflv_1949|M.gilvum_PYR-GCK          FHARIAEEAPENGFGIDDVADALVRKLGNRVPAVLAG----ESISLEDQL
Mvan_4776|M.vanbaalenii_PYR-1       FHARIAEEAPHNSFDVDDVADALVRKLGNRVPAVLAG----ESISLEDQL
MAB_1158|M.abscessus_ATCC_1997      FHARIAEDAPEHPFNIDDVAETLLSKLGNRIPVLLGAGGDSASISLEEQL
                                    *******:*.   * :**** :*: ***** * :*..     .::*::*:

TH_0915|M.thermoresistible__bu      AQWEERKALERRSKRNRSCLDDVPTGQPALALAQKVIERVTQAGLPADLI
MSMEG_5422|M.smegmatis_MC2_155      AQWEERKAQEKKVKARASSMDDVPTGQPALALAQKVLARVSQAGLPAELI
Mb1049|M.bovis_AF2122/97            AQWEAAKASEKAR---KSVADDVHTGQPALALAQKVIQRAQKAGLPAHLI
Rv1021|M.tuberculosis_H37Rv         AQWEAAKASEKAR---KSVADDVHTGQPALALAQKVIQRAQKAGLPAHLI
MMAR_4464|M.marinum_M               AQWEEGKAAEKARNPRESVLDDVPTGQPALALAQKVIARVCNAGLPVQLI
MUL_4633|M.ulcerans_Agy99           AQWEEGKAAEKARNPRESVLDDVPTGQPALALAQKVIARVCNAGLPVQLI
MAV_1162|M.avium_104                AQWEERKAAEKPR---KSVMDDVHTGQPALALAQKVIGRAEKAGLPADLI
Mflv_1949|M.gilvum_PYR-GCK          AQWEQRKALERSTR--RSSMDDIPTAQPALALAQKVLARAETAGVPVDLI
Mvan_4776|M.vanbaalenii_PYR-1       AQWEQRKALERSTR--ESIMDDIPTAQPALALAQKVLARAETGGVPHDLI
MAB_1158|M.abscessus_ATCC_1997      AQWEERKAEEKKDR--DSCLDGISSSQPALALTQKVLGRVTAAGLPAELI
                                    ****  ** *:      *  *.: :.******:***: *.  .*:* .**

TH_0915|M.thermoresistible__bu      PSTITSVAVSAGSDAEHVLRTHVLEFMDTVRRVEEAVAAVRRGEDVPEEL
MSMEG_5422|M.smegmatis_MC2_155      PASLTSVSVSADTDSENELRTAVLEFMDTVREVEAAVAAGRRGEDVPEEL
Mb1049|M.bovis_AF2122/97            PDEITSVSVSADVDAENTLRTAVLDFIDRLRCAERAIAVARRGSNVAEQL
Rv1021|M.tuberculosis_H37Rv         PDEITSVSVSADVDAENTLRTAVLDFIDRLRCAERAIAVARRGSNVAEQL
MMAR_4464|M.marinum_M               PAEITSIAVSADTDAENCLRAAVLDFSDNVRRAERAIVAARRGDAVAEEL
MUL_4633|M.ulcerans_Agy99           PAEITSIAVSADIDAENCLRAAVLDFSDNVRRAERAIVAARRGDAVAEEL
MAV_1162|M.avium_104                PPQVTSIAISADVDAESALRTAVLDFVATVRGVERSIAAARRGTSVPDEF
Mflv_1949|M.gilvum_PYR-GCK          PDAVTKVTVTADFDAENALRTAVLEFMADVRVAERAAGAARRGADVAEEL
Mvan_4776|M.vanbaalenii_PYR-1       PAAITSVAVSADIDAENALRSAVLEFMADVRDAERAATAARRGADVAEEL
MAB_1158|M.abscessus_ATCC_1997      PAQLLSVRIDPDGDAENQLRADALEFMDTVRRAEKDILRGRRGDDVASEL
                                    *  : .: : .. *:*  **: .*:*   :* .*      ***  *..::

TH_0915|M.thermoresistible__bu      DVAPLDDITEEEWRTYWPTVSAAEAGTVAEVDAE----------------
MSMEG_5422|M.smegmatis_MC2_155      DVAPLGVISEDEWRAYWP--------------------------------
Mb1049|M.bovis_AF2122/97            DVTPLGVITEQEWLAHWPTAVN----------------------------
Rv1021|M.tuberculosis_H37Rv         DVTPLGVITEQEWLAHWPTAVN----------------------------
MMAR_4464|M.marinum_M               DMAPVGTITEQEWLVHWPSGSAGADVAPEPVVDEEPPQEPAEPEEQVEAP
MUL_4633|M.ulcerans_Agy99           DMAPVGTITEQEWLVHWPSGSAGADVAPEPVVDEEPPQEPAEPEEQVEAP
MAV_1162|M.avium_104                DIAPLGEISEQEWRQHWPAGDTDPEPAP----------------------
Mflv_1949|M.gilvum_PYR-GCK          DDAPRGGITEDEWRAAWPREIA----------------------------
Mvan_4776|M.vanbaalenii_PYR-1       DDAPHGVISADEWRAHWPGADE----------------------------
MAB_1158|M.abscessus_ATCC_1997      DVSDLREVSTEEWRAHWRQAPADPAAATETDLTAE---------------
                                    * :    :: :**   *                                 

TH_0915|M.thermoresistible__bu      -----TVSGAESDAEPAHSGDGEPGDGEPGDGAAADEP
MSMEG_5422|M.smegmatis_MC2_155      --------GAESSAS-----EAEPEE------------
Mb1049|M.bovis_AF2122/97            ----------DSRGG------SKKRKGMR---------
Rv1021|M.tuberculosis_H37Rv         ----------DSRGG------SKKRKGMR---------
MMAR_4464|M.marinum_M               AEGETPKESRESRGG------SKKRKGRR---------
MUL_4633|M.ulcerans_Agy99           AEGETPKESRESRGG------SKKRKGRR---------
MAV_1162|M.avium_104                -----AEQLTDDAGG------DEN--------------
Mflv_1949|M.gilvum_PYR-GCK          ----------ESASE------PA---------------
Mvan_4776|M.vanbaalenii_PYR-1       ----------PVAEE------PDAAEG-----------
MAB_1158|M.abscessus_ATCC_1997      ------EQQPDVHDD------EEAADSGRPKSA-----