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VARSYDFAQVDVFSATPYMGNPVAVVLDAAGLDDETMQRVARWTNLSETTFVLPPEDPNAHHKLRIFTPG GELAFAGHPTLGSAHAWLEHRESPGCADHIVQECGAGLVQLRRHHGMLSFAAPPMRRTGDLDEAYRTQIV AAFGIARDQVLAHQWVDNGPGWAVVQLATAQEVLDLEPDFSQMSAAMVGAIGAYPSGSEHAFELRTFAPG VGVAEDPVCGSMNAGVAQWLTSTGTAPLSYTVSQGARLARTGEISITTDPDGVVWVSGATSTCFKGTALF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2768 | - | - | 100% (280) | hypothetical protein MUL_2768 |
| M. ulcerans Agy99 | MUL_3359 | - | 2e-07 | 25.60% (250) | hypothetical protein MUL_3359 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2735 | - | 2e-09 | 26.00% (250) | hypothetical protein Mb2735 |
| M. gilvum PYR-GCK | Mflv_3953 | - | 6e-12 | 28.64% (213) | PhzF family phenazine biosynthesis protein |
| M. tuberculosis H37Rv | Rv2716 | - | 2e-09 | 26.00% (250) | hypothetical protein Rv2716 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3035 | - | 1e-11 | 48.39% (93) | hypothetical protein MAB_3035 |
| M. marinum M | MMAR_3536 | - | 1e-160 | 97.86% (280) | hypothetical protein MMAR_3536 |
| M. avium 104 | MAV_3610 | - | 4e-09 | 28.64% (213) | thymidylate synthase |
| M. smegmatis MC2 155 | MSMEG_2744 | - | 1e-11 | 28.00% (250) | thymidylate synthase |
| M. thermoresistible (build 8) | TH_0183 | - | 7e-14 | 29.64% (253) | CONSERVED HYPOTHETICAL PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_2444 | - | 6e-09 | 25.30% (249) | PhzF family phenazine biosynthesis protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3953|M.gilvum_PYR-GCK --MAIDVTVLRVFTDQDGRFGNPLG-VVDASTVDPGDRQRIATELGYSET
Mvan_2444|M.vanbaalenii_PYR-1 --MAIDVTVLRVFTDRDGRFGNPLG-VVDASTVQAADRQRIATELGFSET
MSMEG_2744|M.smegmatis_MC2_155 --MAIDVTVLRVFTDSDGKFGNPLG-VVDNSTVDPADRQRIAKELGYSET
TH_0183|M.thermoresistible__bu --MGLDVTVLRVFTDPDGKFGNPLG-VVDDAAVDPADRQRIATELGYSET
Mb2735|M.bovis_AF2122/97 --MAIEVSVLRVFTDSDGNFGNPLG-VINASKVEHRDRQQLAAQSGYSET
Rv2716|M.tuberculosis_H37Rv --MAIEVSVLRVFTDSDGNFGNPLG-VINASKVEHRDRQQLAAQSGYSET
MAV_3610|M.avium_104 --MGIDVTVLRVFADSDGNFGNPLG-VVDAGRVEVAGRQRLATQLGYSET
MAB_3035|M.abscessus_ATCC_1997 --MSVDVAVVRVFTDETGNFGNPLG-IVNGADVGAADRQQVAARLGFSET
MUL_2768|M.ulcerans_Agy99 MARSYDFAQVDVFSATP-YMGNPVAVVLDAAGLDDETMQRVARWTNLSET
MMAR_3536|M.marinum_M MARSYDFAQVDVFSATP-YMGNPVAVVLDAAGLDDETMQRVARWTNLSET
. :.: : **: :***:. ::: . : *::* . ***
Mflv_3953|M.gilvum_PYR-GCK VFITLPPEGTHSAHAHIHTPTLELPFAGHPTVG-AAWWLRDRGTP----I
Mvan_2444|M.vanbaalenii_PYR-1 VFITLPREGTHSASAHIHTPTTQLPFAGHPTVG-ASWWLKDRGLP----I
MSMEG_2744|M.smegmatis_MC2_155 IFIDLPGPDSHTAHARIFTPASELPFAGHPTVG-AAWYLRDIGRP----I
TH_0183|M.thermoresistible__bu VFVEVPQSGTNTAQARIFTPVTEMRFAGHPTVG-AAWWLREQGRP----I
Mb2735|M.bovis_AF2122/97 IFVDLPSPGSTTAHATIHTPRTEIPFAGHPTVG-ASWWLRERGTP----I
Rv2716|M.tuberculosis_H37Rv IFVDLPSPGSTTAHATIHTPRTEIPFAGHPTVG-ASWWLRERGTP----I
MAV_3610|M.avium_104 VFVDLPAPGSSTAHATIYTPRTELPFAGHPTVG-AAWWLREQGSP----I
MAB_3035|M.abscessus_ATCC_1997 VFVDLPAEGSNTAHLRIFTPAAELPFAGHPTVG-LAWWLRERGTP----V
MUL_2768|M.ulcerans_Agy99 TFVLPPEDPNAHHKLRIFTPGGELAFAGHPTLGSAHAWLEHRESPGCADH
MMAR_3536|M.marinum_M TFVLPPEDPNAHYKLRIFTPGGELAFAGHPTLGSAHAWLEHRESPGCADR
*: * . *.** :: ******:* :*.. *
Mflv_3953|M.gilvum_PYR-GCK KTLQVPAGIVQISYPGELAAVSAR--------------------------
Mvan_2444|M.vanbaalenii_PYR-1 KTLQVPAGIVQVTYTGDLTAVSAR--------------------------
MSMEG_2744|M.smegmatis_MC2_155 KTLQVPAGIVQVTYDGDLAAISAR--------------------------
TH_0183|M.thermoresistible__bu HTLQVPAGIVQVSYRDDLTEVSAR--------------------------
Mb2735|M.bovis_AF2122/97 NTLQVPAGIVQVSYHGDLTAISAR--------------------------
Rv2716|M.tuberculosis_H37Rv NTLQVPAGIVQVSYHGDLTAISAR--------------------------
MAV_3610|M.avium_104 NTLAVPAGIVQVGYDGPCARISAR--------------------------
MAB_3035|M.abscessus_ATCC_1997 NTLQVPAGVLQVSYD-DRTWIRAR--------------------------
MUL_2768|M.ulcerans_Agy99 IVQECGAGLVQLRRHHGMLSFAAPPMRRTGDLDEAYRTQIVAAFGIARDQ
MMAR_3536|M.marinum_M IVQECGAGLVQLRRHHGMLSFAAPPMRRTGDLDEAYLTQIVAAFGIARDQ
. **::*: . *
Mflv_3953|M.gilvum_PYR-GCK ------AEWAPTFSIYDVATLDELAAADPDDYAD---EAEHYLWTWIDQA
Mvan_2444|M.vanbaalenii_PYR-1 ------ADWAPDFSINHVASLDDLAAADPDDYADD--EAEHYLWTWLDEA
MSMEG_2744|M.smegmatis_MC2_155 ------SEWAPEFAIYDLPSAEELMSADPDDYDD---DVQHYLWTWSDKN
TH_0183|M.thermoresistible__bu ------AEWAPEFVIRELETAEELLAADPDEYPD---DIGHYLWTWTDRE
Mb2735|M.bovis_AF2122/97 ------SEWAPEFAIHDLDSLDALAAADPADFPD---DIAHYLWTWTDRS
Rv2716|M.tuberculosis_H37Rv ------SEWAPEFAIHDLDSLDALAAADPADFPD---DIAHYLWTWTDRS
MAV_3610|M.avium_104 ------SEWAPELALHEFGSAEEVLAADPTEFSD---DTAR---------
MAB_3035|M.abscessus_ATCC_1997 ------SDWAPETDFHESDSPADVEAADPADYPD---ELLHCIWAWQNRD
MUL_2768|M.ulcerans_Agy99 VLAHQWVDNGPGWAVVQLATAQEVLDLEP-DFSQMSAAMVGAIGAYPSGS
MMAR_3536|M.marinum_M VLAHQWVDNGPGWAVVQLATAQEVLDLEP-DFSQMSSAMVGAIGAYPSGS
: .* . . : : :* :: :
Mflv_3953|M.gilvum_PYR-GCK AGTIRARMFAPHMGIREDEATGAAAVRITEYLSRD------LTIVQGK--
Mvan_2444|M.vanbaalenii_PYR-1 ADTIRSRMFAPHLGIREDEATGAAAVRITEHLSRD------LTIVQGQ--
MSMEG_2744|M.smegmatis_MC2_155 EGVLRSRMFATNLGIREDEATGAAAVRITDYLSRD------LTIVQGK--
TH_0183|M.thermoresistible__bu HGQIRARMFANNLGIPEDEATGSAAVRITEFLSRD------LTIVQGK--
Mb2735|M.bovis_AF2122/97 AGSLRARMFAANLGVTEDEATGAAAIRITDYLSRD------LTITQGK--
Rv2716|M.tuberculosis_H37Rv AGSLRARMFAANLGVTEDEATGAAAIRITDYLSRD------LTITQGK--
MAV_3610|M.avium_104 --ALRSRMFAANLGVPEDEATGSAAMRITDYLSRD------LRITQGK--
MAB_3035|M.abscessus_ATCC_1997 ANLVRSRVFASDLGVDEDEATGSVAARLTDLLSRD------LIINQGK--
MUL_2768|M.ulcerans_Agy99 EHAFELRTFAPGVGVAEDPVCGSMNAGVAQWLTSTGTAPLSYTVSQGARL
MMAR_3536|M.marinum_M EHAFELRTFAPGVGVAEDPVCGSMNAGVAQWLTSTGTAPLSYTVSQGARL
.. * ** :*: ** . *: ::: *: : **
Mflv_3953|M.gilvum_PYR-GCK --GSVLQTTWSAYGWVEVAGRVVDDGQRQID-
Mvan_2444|M.vanbaalenii_PYR-1 --GSVIETKWSPEGWVQIAGRVVDDGQRQID-
MSMEG_2744|M.smegmatis_MC2_155 --GSVIRTRWSPEGWVQVAGRVVNDGTRQLEL
TH_0183|M.thermoresistible__bu --GSIIETRWNPEGWVQIAGRVARDEIRTLD-
Mb2735|M.bovis_AF2122/97 --GSLIHTTWSPEGWVRVAGRVVSDGVAQLD-
Rv2716|M.tuberculosis_H37Rv --GSLIHTTWSPEGWVRVAGRVVSDGVAQLD-
MAV_3610|M.avium_104 --GSVIETSWSAEGWVGVAGRVVNDGVRHLD-
MAB_3035|M.abscessus_ATCC_1997 --GSQIFTQWSPEGWVTIGGRVVADQPLTLD-
MUL_2768|M.ulcerans_Agy99 ARTGEISITTDPDGVVWVSGATSTCFKGTALF
MMAR_3536|M.marinum_M ARAGEISITTDADGVVWVSGATSTCFKGTALF
. : .. * * :.* .