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AIDVTVLRVFTDSDGKFGNPLGVVDNSTVDPADRQRIAKELGYSETIFIDLPGPDSHTAHARIFTPASEL PFAGHPTVGAAWYLRDIGRPIKTLQVPAGIVQVTYDGDLAAISARSEWAPEFAIYDLPSAEELMSADPDD YDDDVQHYLWTWSDKNEGVLRSRMFATNLGIREDEATGAAAVRITDYLSRDLTIVQGKGSVIRTRWSPEG WVQVAGRVVNDGTRQLEL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2744 | - | - | 100% (229) | thymidylate synthase |
| M. smegmatis MC2 155 | MSMEG_6780 | - | 6e-07 | 46.15% (65) | phenazine biosynthesis protein PhzF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2735 | - | 5e-97 | 71.93% (228) | hypothetical protein Mb2735 |
| M. gilvum PYR-GCK | Mflv_3953 | - | 1e-100 | 74.12% (228) | PhzF family phenazine biosynthesis protein |
| M. tuberculosis H37Rv | Rv2716 | - | 5e-97 | 71.93% (228) | hypothetical protein Rv2716 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3035 | - | 3e-77 | 59.01% (222) | hypothetical protein MAB_3035 |
| M. marinum M | MMAR_1996 | - | 9e-92 | 67.54% (228) | hypothetical protein MMAR_1996 |
| M. avium 104 | MAV_3610 | - | 1e-85 | 67.98% (228) | thymidylate synthase |
| M. thermoresistible (build 8) | TH_0183 | - | 8e-98 | 71.49% (228) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3359 | - | 9e-91 | 67.11% (228) | hypothetical protein MUL_3359 |
| M. vanbaalenii PYR-1 | Mvan_2444 | - | 6e-96 | 72.05% (229) | PhzF family phenazine biosynthesis protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3953|M.gilvum_PYR-GCK MAIDVTVLRVFTDQDGRFGNPLGVVDASTVDPGDRQRIATELGYSETVFI
Mvan_2444|M.vanbaalenii_PYR-1 MAIDVTVLRVFTDRDGRFGNPLGVVDASTVQAADRQRIATELGFSETVFI
MSMEG_2744|M.smegmatis_MC2_155 MAIDVTVLRVFTDSDGKFGNPLGVVDNSTVDPADRQRIAKELGYSETIFI
TH_0183|M.thermoresistible__bu MGLDVTVLRVFTDPDGKFGNPLGVVDDAAVDPADRQRIATELGYSETVFV
Mb2735|M.bovis_AF2122/97 MAIEVSVLRVFTDSDGNFGNPLGVINASKVEHRDRQQLAAQSGYSETIFV
Rv2716|M.tuberculosis_H37Rv MAIEVSVLRVFTDSDGNFGNPLGVINASKVEHRDRQQLAAQSGYSETIFV
MMAR_1996|M.marinum_M MGIDVTVLRVFTDPTGNFGNPLGVVDASKVEPRDRQHLASRLAYSETVFV
MUL_3359|M.ulcerans_Agy99 MGIDVTVLRVFTDPIGNFGNPLGVVDASKVEPRDRQHLASRLAYSETVFV
MAV_3610|M.avium_104 MGIDVTVLRVFADSDGNFGNPLGVVDAGRVEVAGRQRLATQLGYSETVFV
MAB_3035|M.abscessus_ATCC_1997 MSVDVAVVRVFTDETGNFGNPLGIVNGADVGAADRQQVAARLGFSETVFV
*.::*:*:***:* *.******::: . * .**::* . .:***:*:
Mflv_3953|M.gilvum_PYR-GCK TLPPEGTHSAHAHIHTPTLELPFAGHPTVGAAWWLRDRGTPIKTLQVPAG
Mvan_2444|M.vanbaalenii_PYR-1 TLPREGTHSASAHIHTPTTQLPFAGHPTVGASWWLKDRGLPIKTLQVPAG
MSMEG_2744|M.smegmatis_MC2_155 DLPGPDSHTAHARIFTPASELPFAGHPTVGAAWYLRDIGRPIKTLQVPAG
TH_0183|M.thermoresistible__bu EVPQSGTNTAQARIFTPVTEMRFAGHPTVGAAWWLREQGRPIHTLQVPAG
Mb2735|M.bovis_AF2122/97 DLPSPGSTTAHATIHTPRTEIPFAGHPTVGASWWLRERGTPINTLQVPAG
Rv2716|M.tuberculosis_H37Rv DLPSPGSTTAHATIHTPRTEIPFAGHPTVGASWWLRERGTPINTLQVPAG
MMAR_1996|M.marinum_M DLPATGSHTAHATIYTPRTDIAFAGHPTVGASWWLREQGTPVNTLQVPAG
MUL_3359|M.ulcerans_Agy99 DLPATGSHTAHATTYTPRTDIAFAGHPTVGASWWLREQGTPVNTLQVPAG
MAV_3610|M.avium_104 DLPAPGSSTAHATIYTPRTELPFAGHPTVGAAWWLREQGSPINTLAVPAG
MAB_3035|M.abscessus_ATCC_1997 DLPAEGSNTAHLRIFTPAAELPFAGHPTVGLAWWLRERGTPVNTLQVPAG
:* .: :* .** :: ******** :*:*:: * *::** ****
Mflv_3953|M.gilvum_PYR-GCK IVQISYPGELAAVSARAEWAPTFSIYDVATLDELAAADPDDYAD-EAEHY
Mvan_2444|M.vanbaalenii_PYR-1 IVQVTYTGDLTAVSARADWAPDFSINHVASLDDLAAADPDDYADDEAEHY
MSMEG_2744|M.smegmatis_MC2_155 IVQVTYDGDLAAISARSEWAPEFAIYDLPSAEELMSADPDDYDD-DVQHY
TH_0183|M.thermoresistible__bu IVQVSYRDDLTEVSARAEWAPEFVIRELETAEELLAADPDEYPD-DIGHY
Mb2735|M.bovis_AF2122/97 IVQVSYHGDLTAISARSEWAPEFAIHDLDSLDALAAADPADFPD-DIAHY
Rv2716|M.tuberculosis_H37Rv IVQVSYHGDLTAISARSEWAPEFAIHDLDSLDALAAADPADFPD-DIAHY
MMAR_1996|M.marinum_M LVQVHHDRDLTTISARAEWAPEFAIHDLDSPDALAAADPSDFAD-DTAHY
MUL_3359|M.ulcerans_Agy99 LVQVHHDRDLTTISARAEWAPEFAIHDLDSPDALAAADPSDFAD-DTAHY
MAV_3610|M.avium_104 IVQVGYDGPCARISARSEWAPELALHEFGSAEEVLAADPTEFSD-DTAR-
MAB_3035|M.abscessus_ATCC_1997 VLQVSYD-DRTWIRARSDWAPETDFHESDSPADVEAADPADYPD-ELLHC
::*: : : : **::*** : . : : :*** :: * : :
Mflv_3953|M.gilvum_PYR-GCK LWTWIDQAAGTIRARMFAPHMGIREDEATGAAAVRITEYLSRDLTIVQGK
Mvan_2444|M.vanbaalenii_PYR-1 LWTWLDEAADTIRSRMFAPHLGIREDEATGAAAVRITEHLSRDLTIVQGQ
MSMEG_2744|M.smegmatis_MC2_155 LWTWSDKNEGVLRSRMFATNLGIREDEATGAAAVRITDYLSRDLTIVQGK
TH_0183|M.thermoresistible__bu LWTWTDREHGQIRARMFANNLGIPEDEATGSAAVRITEFLSRDLTIVQGK
Mb2735|M.bovis_AF2122/97 LWTWTDRSAGSLRARMFAANLGVTEDEATGAAAIRITDYLSRDLTITQGK
Rv2716|M.tuberculosis_H37Rv LWTWTDRSAGSLRARMFAANLGVTEDEATGAAAIRITDYLSRDLTITQGK
MMAR_1996|M.marinum_M LWTWTDEAAGELRSRMFASNLGVEEDEATGSAAMRLTDYLSRDLTITQGK
MUL_3359|M.ulcerans_Agy99 LWTWTDDAAGDLRSRMFASNLGVEEDEATGSAAMRLTDYLSRDLTITQGK
MAV_3610|M.avium_104 ----------ALRSRMFAANLGVPEDEATGSAAMRITDYLSRDLRITQGK
MAB_3035|M.abscessus_ATCC_1997 IWAWQNRDANLVRSRVFASDLGVDEDEATGSVAARLTDLLSRDLIINQGK
:*:*:** .:*: ******:.* *:*: ***** * **:
Mflv_3953|M.gilvum_PYR-GCK GSVLQTTWSAYGWVEVAGRVVDDGQRQID-
Mvan_2444|M.vanbaalenii_PYR-1 GSVIETKWSPEGWVQIAGRVVDDGQRQID-
MSMEG_2744|M.smegmatis_MC2_155 GSVIRTRWSPEGWVQVAGRVVNDGTRQLEL
TH_0183|M.thermoresistible__bu GSIIETRWNPEGWVQIAGRVARDEIRTLD-
Mb2735|M.bovis_AF2122/97 GSLIHTTWSPEGWVRVAGRVVSDGVAQLD-
Rv2716|M.tuberculosis_H37Rv GSLIHTTWSPEGWVRVAGRVVSDGVAQLD-
MMAR_1996|M.marinum_M GSIINTTWSAEGWVAVAGRVVSDGVTHVD-
MUL_3359|M.ulcerans_Agy99 GSIINTTWSAEGWVAVAGRVVSDGVTHVD-
MAV_3610|M.avium_104 GSVIETSWSAEGWVGVAGRVVNDGVRHLD-
MAB_3035|M.abscessus_ATCC_1997 GSQIFTQWSPEGWVTIGGRVVADQPLTLD-
** : * *.. *** :.***. * ::