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IPTRDVELRWRASPLTLAVATCAGVALAAALIAGRWQLIAFAAPLLGVLCSIYWQRPVPTVHVHAEPDLQ RCFEDERVGVKVWATVDSTAGEGSEAVLVTVRAPAGMQLDIDASTSRQAKSVEVVTQRWGRYPIEARVDV VARGGLLIGDGTVEAAQVVVFPLTPPQPTAIPQTELLDRLGAHLTRYIGPGVEYADIRPYVPGDQLRAVN WAVSARRGRLHVTQRLTDRAADVIVLIDTYRQPPGPASEATERVARGAAQVVQTALRNGDRAGIIALGGN RPRWMGADIGQRQFYRVLDTVLGSGDRFEKTTGTLAPRAAVPTGAIVIAFSTLLDTEFALALIDLRKRGH VVVAVDVLDGAPFEGEQDPLVVRMWALQRAGMYRDMATVGVDVLDWPGNRALEQSMGALPDRRRRIRGRL RGSV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2476 | - | - | 100% (425) | hypothetical protein MUL_2476 |
| M. ulcerans Agy99 | MUL_1489 | - | 1e-06 | 25.41% (181) | hypothetical protein MUL_1489 |
| M. ulcerans Agy99 | MUL_4276 | - | 3e-06 | 33.33% (78) | hypothetical protein MUL_4276 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3188c | - | 0.0 | 78.33% (420) | hypothetical protein Mb3188c |
| M. gilvum PYR-GCK | Mflv_0475 | - | 1e-161 | 68.37% (411) | hypothetical protein Mflv_0475 |
| M. tuberculosis H37Rv | Rv3163c | - | 0.0 | 78.57% (420) | hypothetical protein Rv3163c |
| M. leprae Br4923 | MLBr_01809 | - | 3e-10 | 28.73% (181) | hypothetical protein MLBr_01809 |
| M. abscessus ATCC 19977 | MAB_1908c | - | 1e-112 | 51.68% (416) | hypothetical protein MAB_1908c |
| M. marinum M | MMAR_1400 | - | 0.0 | 98.12% (425) | hypothetical protein MMAR_1400 |
| M. avium 104 | MAV_4050 | - | 1e-161 | 75.20% (375) | hypothetical protein MAV_4050 |
| M. smegmatis MC2 155 | MSMEG_3867 | - | 1e-142 | 61.41% (412) | ATPase family protein associated with various cellular |
| M. thermoresistible (build 8) | TH_0583 | - | 1e-136 | 59.81% (423) | POSSIBLE CONSERVED SECRETED PROTEIN |
| M. vanbaalenii PYR-1 | Mvan_0181 | - | 1e-154 | 67.07% (410) | hypothetical protein Mvan_0181 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2476|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1400|M.marinum_M --------------------------------------------------
Mb3188c|M.bovis_AF2122/97 --------------------------------------------------
Rv3163c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4050|M.avium_104 --------------------------------------------------
Mflv_0475|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0181|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0583|M.thermoresistible__bu --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155 MTSQANVDVATAAAARSVLDEIEKAVVGKRDALTLILTTLLARGHVLIED
MAB_1908c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01809|M.leprae_Br4923 --------------------------------------------------
MUL_2476|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1400|M.marinum_M --------------------------------------------------
Mb3188c|M.bovis_AF2122/97 --------------------------------------------------
Rv3163c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4050|M.avium_104 --------------------------------------------------
Mflv_0475|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0181|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0583|M.thermoresistible__bu --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155 LPGLGKTLIARSFAAALGLKFTRVQFTPDLLPADLLGSTVYDMQSGRFEF
MAB_1908c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01809|M.leprae_Br4923 --------------------------------------------------
MUL_2476|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1400|M.marinum_M --------------------------------------------------
Mb3188c|M.bovis_AF2122/97 --------------------------------------------------
Rv3163c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4050|M.avium_104 --------------------------------------------------
Mflv_0475|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0181|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0583|M.thermoresistible__bu --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155 RPGPIFTNLLLADEINRTPPKTQAALLEAMAEGQVSIDGQTHRLPAPFIV
MAB_1908c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01809|M.leprae_Br4923 --------------------------------------------------
MUL_2476|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1400|M.marinum_M --------------------------------------------------
Mb3188c|M.bovis_AF2122/97 --------------------------------------------------
Rv3163c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4050|M.avium_104 --------------------------------------------------
Mflv_0475|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0181|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0583|M.thermoresistible__bu --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155 LATDNPIEYEGTYPLPEAQLDRFSVRLELKYLSEQDETAMLRRRLDRGSA
MAB_1908c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01809|M.leprae_Br4923 --------------------------------------------------
MUL_2476|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1400|M.marinum_M --------------------------------------------------
Mb3188c|M.bovis_AF2122/97 --------------------------------------------------
Rv3163c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4050|M.avium_104 --------------------------------------------------
Mflv_0475|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0181|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0583|M.thermoresistible__bu --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155 EAGVAEVVDGPRFLAMREAVEQVSVHDDVLRYVVALRGRDAPPPAGCGRR
MAB_1908c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01809|M.leprae_Br4923 --------------------------------------------------
MUL_2476|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1400|M.marinum_M --------------------------------------------------
Mb3188c|M.bovis_AF2122/97 --------------------------------------------------
Rv3163c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4050|M.avium_104 --------------------------------------------------
Mflv_0475|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0181|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0583|M.thermoresistible__bu --------------------------------------------------
MSMEG_3867|M.smegmatis_MC2_155 QPPRRTRPRATREGQGLAARAGLRHPRGRQDTRGRGDGAPHQPAPGDVGA
MAB_1908c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01809|M.leprae_Br4923 --------------------------------------------------
MUL_2476|M.ulcerans_Agy99 ------------------------MIPTRDVELRWRASPLTLAVATCAGV
MMAR_1400|M.marinum_M ------------------------MIQTRDVELRWRASPLTLAVATCAAV
Mb3188c|M.bovis_AF2122/97 ------------------------MIQTCEVELRWRASQLTLAIATCAGV
Rv3163c|M.tuberculosis_H37Rv ------------------------MIQTCEVELRWRASQLTLAIATCAGV
MAV_4050|M.avium_104 --------------------------------------------------
Mflv_0475|M.gilvum_PYR-GCK ---------------------------MVAVELRWRASALTQSIATCVAA
Mvan_0181|M.vanbaalenii_PYR-1 ---------------------------MTAVELRWRPSPLTRSIATCAAA
TH_0583|M.thermoresistible__bu ---------------VTITPPGPSNMSGIAVEPRWRASPLTLALCSCAAV
MSMEG_3867|M.smegmatis_MC2_155 QHPRCRRHERTAAPAPRAPCGQPAMTVGVHVPLRWGASPLTKSVATAAAG
MAB_1908c|M.abscessus_ATCC_199 -------------------------------MITWRASALISALAACTGA
MLBr_01809|M.leprae_Br4923 --------------------------------------------------
MUL_2476|M.ulcerans_Agy99 ALAAALIAGRWQLIAFAAPLLGVLCSIYWQRPVPTVHVHAEPDLQRCFED
MMAR_1400|M.marinum_M ALAAALIAGRWQLIAFAAPLLGVLCSIYWQRPVPTVHVHAEPDLQRCFED
Mb3188c|M.bovis_AF2122/97 ALAAAVVAGRWQLIAFAAPLLGVLCSISWQRPVPVIQVHGDPDSQRCFEN
Rv3163c|M.tuberculosis_H37Rv ALAAAVVAGRWQLIAFAAPLLGVLCSISWQRPVPVIQVHGDPDSQRCFEN
MAV_4050|M.avium_104 ----------------------MLGTISWQPRVPAVAVHAEPDTQRCFEG
Mflv_0475|M.gilvum_PYR-GCK AITVALVAGRWELVAFAAPLAGALCSIGWQRRLPTVTVTGSPPFQRCFED
Mvan_0181|M.vanbaalenii_PYR-1 AIVAALLAGRWELAAFAAPLLGVLCSIGWQRGKPSVTVQAEPVFQRCFEG
TH_0583|M.thermoresistible__bu TLAAAVIGQRWQLVIFAAPLIGVLASVVRQPPPPRVWLRGHPDPGRCFEG
MSMEG_3867|M.smegmatis_MC2_155 AMLIAVLGFRWQLVIFASPLLGVLCSAYWQRPRVSVEVGAEPATVRCFEN
MAB_1908c|M.abscessus_ATCC_199 ALALAVMTGRWQLVVFAAPFVGALAGASRRPPAARAWVTDEPEPLRCLES
MLBr_01809|M.leprae_Br4923 -MIDPNPAAKPGVFHPPSMQRGQIDDPKLSAALRTLELTVKRKLDGVLHG
: : :..
MUL_2476|M.ulcerans_Agy99 ERVGVKVWATVDSTAGEGSEAVLVTVRAPAGMQLDIDASTSRQAKSVEVV
MMAR_1400|M.marinum_M ERVGVKVWATVDSAAGEGSEAVLVTVRAPAGMQLDIDASSSRQAKSVEVV
Mb3188c|M.bovis_AF2122/97 EHVRVTVWVTTESVD----AAVELTVSALAGMQFEALESVSRRTTTVSAV
Rv3163c|M.tuberculosis_H37Rv EHVRVTVWVTTESVD----AAVELTVSALAGMQFEALESVSRRTTTVSAV
MAV_4050|M.avium_104 EPAHVTVWGIEEQGP----CAVRLTVPPVEGMELQFGESGSRRGKTVRAT
Mflv_0475|M.gilvum_PYR-GCK EQVSVGMTAVADDGA-----AVTLDCTAPAPMVLTHRPAG-----ELTVQ
Mvan_0181|M.vanbaalenii_PYR-1 ESVLVTVSAGAEDGS-----AVTLDCSVVTGMELVGPTSLP----TLSVR
TH_0583|M.thermoresistible__bu EEVRVTVTVSADPPG----TALHLRVDDVSGAQVRMLEQRPER-VVAAVS
MSMEG_3867|M.smegmatis_MC2_155 ESAELSVRVSSSAGA-----DARLRVDSVEGLRLEPGDRAGPE-QRVRAN
MAB_1908c|M.abscessus_ATCC_199 ETITVAVSVESTGPA----VVCGLRPALVEGLRIDADRPAAPNQLTMRTS
MLBr_01809|M.leprae_Br4923 DHLGLISGPGSEPGE---------SRVYQPGDDVRRMDWAVTARTTHPHV
: : .
MUL_2476|M.ulcerans_Agy99 TQRWGRYPIEARVDVVARGGLLIGDG-TVEAAQVVVFPLTPPQPTAIPQT
MMAR_1400|M.marinum_M TQRWGRYPIKARVDVVARGGLLMGDG-TVEAAQVVVFPLTPPQPTAIPQT
Mb3188c|M.bovis_AF2122/97 AQRWGRYPIRARVAVVARGGLLMGAG-TVDAAEIVVFPLTPPQSTPLPQT
Rv3163c|M.tuberculosis_H37Rv AQRWGRYPIRARVAVVARGGLLMGAG-TVDAAEIVVFPLTPPQSTPLPQT
MAV_4050|M.avium_104 AQRWGRYHVAARVDVLARGGLLSGTA-LVDAAEVIVFPLTPPQPTPIPRT
Mflv_0475|M.gilvum_PYR-GCK SSRWGRYPVRAGVRVCGRGGLVTGTG-TVDAAEVCVFPLAPAQSTAIPRT
Mvan_0181|M.vanbaalenii_PYR-1 ASRWGRYPLLATVRVGGRGGLLEGTG-TADAAEVCVFPVAPPQSTAIPRT
TH_0583|M.thermoresistible__bu AHRWGRYPVRARVDVPAAGGLLTGTG-AVDVAEIVVFPLAPPESTVLPHG
MSMEG_3867|M.smegmatis_MC2_155 ASRWGRYPLRAHVTVTAPGGLVTGTG-TVEAAELYVFPLAAPHLTPMPRA
MAB_1908c|M.abscessus_ATCC_199 AQRWGRYRVPVEVRSVSASGLWAGTALTLPASELRVYPLADPQDVALPPA
MLBr_01809|M.leprae_Br4923 RQMIADRELETWMVIDMSASLDFGTT----ICEKRDLAVAAAAAITFLNS
. : . : ..* * .: .:: . :
MUL_2476|M.ulcerans_Agy99 ELLDRLGAHLTRYIGPGVEYADIRPYVPGDQLRAVNWAVSARRGRLHVTQ
MMAR_1400|M.marinum_M ELLDRLGAHLTRYIGPGVEYADIRPYVPGDQLRAVNWAVSARRGRLHVTQ
Mb3188c|M.bovis_AF2122/97 ELLDRLGAHLTRHVGPGVEYADIRPYVPGDQLRAVNWVVSARRGRLHVTR
Rv3163c|M.tuberculosis_H37Rv ELLDRLGAHLTRHVGPGVEYADIRPYVPGDQLRAVNWVVSARRGRLHVTR
MAV_4050|M.avium_104 ELLDRLGAHLTRHVGPGVEYADIRPYVPGDQLRAVNWAVSARRRQLHVTQ
Mflv_0475|M.gilvum_PYR-GCK DLLDRLGTHLTRHTGPGVEFADIRPYVPGDQLRIVNWPVSARRGTLHITE
Mvan_0181|M.vanbaalenii_PYR-1 DLLDRLGTHLTRHVGPGVEFADIRPYVPGDQLRTVNWPVSARRGALHVTE
TH_0583|M.thermoresistible__bu EMRDRLGTHLTANSGSGVEYADIRPYVPGDQLRTVNWPVSARRGRLHVTQ
MSMEG_3867|M.smegmatis_MC2_155 ELPDRLGTHLTRHTGPGVEYADVRPYVPGDHLRTVNWPVSARRGRLHVTE
MAB_1908c|M.abscessus_ATCC_199 DLPDRIGTRLTRHHGPGVEYADIREYVPGDSLRTVNWRVSAQRGRLHVTD
MLBr_01809|M.leprae_Br4923 GGGNRLGALICN--------------------GARMTRVPARSGRQHEQT
:*:*: : *.*: *
MUL_2476|M.ulcerans_Agy99 RLTDRAADVIVLIDTYRQPPGPASEATERVARGAAQVVQTALRNGDRAGI
MMAR_1400|M.marinum_M RLTDRAADVIVLIDTYRQPPGPASEATERVARGAAQVVQTALRNGDRAGI
Mb3188c|M.bovis_AF2122/97 RLTDRAADVVVLIDMYRQPAGPATEATERVVRGAAQVVQTALRNGDRAGI
Rv3163c|M.tuberculosis_H37Rv RLTDRAADVVVLIDMYRQPAGPATEATERVVRGAAQVVQTALRNGDRAGI
MAV_4050|M.avium_104 RLTDRAADVVVLIDGYRQPAGPATQATERIVRGAAQVVQTALRHGDRAGI
Mflv_0475|M.gilvum_PYR-GCK RLTDRAADVVVLVDTYPQPPGPATAATERTARGAAQVVQSALRYGDRAGL
Mvan_0181|M.vanbaalenii_PYR-1 RLTDRAADVVALVDTYPQPPGPATAATERIARGAAQVVQSALRYGDRAGL
TH_0583|M.thermoresistible__bu RLSERAADVVVLVDAYPQPPGPATEVTERIARGAVQVVQSALRGGDRAGI
MSMEG_3867|M.smegmatis_MC2_155 RLTDRGGDVVVLIDTHDQAPGPATQATERTARGAAQVVQSALRSGDRAGI
MAB_1908c|M.abscessus_ATCC_199 RLTDRAADVVVLIDTYPQPSGPATTATERSARGAAQLVQSVLQRGDRAGV
MLBr_01809|M.leprae_Br4923 LLR-------TIATTPKAPVG---------VRGDLTVAIDALRRPERR--
* .: . * .** :. .*: :*
MUL_2476|M.ulcerans_Agy99 IALGGNRPRWMGADIGQRQFYRVLDTVLGSGDRFEKTT--------GTLA
MMAR_1400|M.marinum_M IALGGNRPRWMGADIGQRQFYRVLDTVLGSGDRFEKTT--------GTLA
Mb3188c|M.bovis_AF2122/97 VALGGNRPRWLGADIGQRQFYRVLDTVLGAGEGFENTT--------GTLA
Rv3163c|M.tuberculosis_H37Rv VALGGNRPRWLGADIGQRQFYRVLDTVLGAGEGFENTT--------GTLA
MAV_4050|M.avium_104 VALGGNRPRWLGADIGQRQFYRVLDTVLAAGGGFEHTT--------GTLA
Mflv_0475|M.gilvum_PYR-GCK VALGGRSTRWLGADIGRRQFYRILDTVLGADDTFEKAT--------GTLA
Mvan_0181|M.vanbaalenii_PYR-1 VALGSRNVRWLGADIGQRQFYRVLDTMLGASDTFQNAT--------GTLA
TH_0583|M.thermoresistible__bu ATLGGRGPRWLGVDLGRRQFYRVVDTMLGAAPGSGPTTPTGPGSGRGTLV
MSMEG_3867|M.smegmatis_MC2_155 VALGGRQPRWLGLDIGRRQFYRVLDAILGAGGGFETTT--------GTLA
MAB_1908c|M.abscessus_ATCC_199 VVLG-SSARWLAPNIGRHQFYRLLDATLDAGEWHSHSA--------SALA
MLBr_01809|M.leprae_Br4923 -----------------RGMAVIISDFLGPINWMRPLR---------AIA
: : ::. * . ::.
MUL_2476|M.ulcerans_Agy99 PRAAVPTGAIVIAFSTLLDTEFALALIDLRKRGHVVVAVDVLDGAPFEGE
MMAR_1400|M.marinum_M PRAAVPAGAIVIAFSTLLDTEFALALIDLRKRGHVVVAVDVLDSAPFEGE
Mb3188c|M.bovis_AF2122/97 PRAAVPAGAVVIAFSTLLDTEFALALIELRKRGHVVVAVDVLDSCPLQDQ
Rv3163c|M.tuberculosis_H37Rv PRAAVPAGAVVIAFSTLLDTEFALALIDLRKRGHVVVAVDVLDSCPLQDQ
MAV_4050|M.avium_104 PRAAVPAGAIVIAFSTLLDTEFALALIDLRRRGHVVLAVDILEGSPSEDE
Mflv_0475|M.gilvum_PYR-GCK PRAAVPTGAIVVAFSTMLDTEFALALIDLRKRGHPVVVVDVLEGSPVEGE
Mvan_0181|M.vanbaalenii_PYR-1 PRPAVPTRAIVIAFSTMLDTEFALALIDLRKRGHPVVAIDVLDGSPLEGD
TH_0583|M.thermoresistible__bu PRPAVPPEAIVVAFSTLLDTDFALALIDLARRGHPVVAVDVLDREPFDG-
MSMEG_3867|M.smegmatis_MC2_155 PRAAVPPGAIVVAFSTMLNTEFAFALIELAKHGHAVVAVDILEGAPFDNP
MAB_1908c|M.abscessus_ATCC_199 PRAAVPPNAIVVAFSTLLNADFGLALTDLRRRGHPVVVVDVLDRLPFREE
MLBr_01809|M.leprae_Br4923 ARHEVLGIEVLDPRDVALPDIGEVVLQDAETG----VTREFTIDAALRDD
.* * :: . .. * ..* : :. :. .
MUL_2476|M.ulcerans_Agy99 --QDPLVVRMWALQRAGMYRDMATVGVDVLDWPGNRALEQSMGALPDRRR
MMAR_1400|M.marinum_M --QDPLVVRMWALQRAGMYRDMATVGVDVLDWPGNRALEQSMGALPDRRR
Mb3188c|M.bovis_AF2122/97 --LDPLVVRMWALQRSAMYRDMATIGVDVLSWPADHSLQQSMGALPNRRR
Rv3163c|M.tuberculosis_H37Rv --LDPLVVRMWALQRSAMYRDMATIGVDVLSWPADHSLQQSMGALPNRRR
MAV_4050|M.avium_104 --QDPLVDRMWALQRSAMYRDMATVGVDIVWWPGDRGLEQSMGVLPDRRR
Mflv_0475|M.gilvum_PYR-GCK --HDPLVHRMWAMQRSFMYRDMATVGVDIVAWPGDATLDQAMALVPARRR
Mvan_0181|M.vanbaalenii_PYR-1 --HDPLVHRMWSMQRSFMYRDMATVGVDVVGWPAAVTLDQAMALVPVHRA
TH_0583|M.thermoresistible__bu --VDPLVGRMWSLQRSFMYRDMRTIGVDVVAWGAGQALDQVLHVVADHRR
MSMEG_3867|M.smegmatis_MC2_155 DGLDPLIPRLWALQRSAMYRDMSTIGIDVVHWRGDIPLQDVMRLIPDRHR
MAB_1908c|M.abscessus_ATCC_199 --PDPIVARWWRLERSRMYRNIAVTGVDVVGWSHDSGLNHAMHLMPRRPR
MLBr_01809|M.leprae_Br4923 ------FARAAAAHCADVSRSLRNCGAPLMSLRTDRDWIADIVRFVESRR
. * . : : *.: * :: : .
MUL_2476|M.ulcerans_Agy99 RIRGRLRGSV--
MMAR_1400|M.marinum_M RIRGRLRGSV--
Mb3188c|M.bovis_AF2122/97 RGRGRASRARLP
Rv3163c|M.tuberculosis_H37Rv RGRGRASRARLP
MAV_4050|M.avium_104 RVRGRLRG----
Mflv_0475|M.gilvum_PYR-GCK RL----------
Mvan_0181|M.vanbaalenii_PYR-1 RR----------
TH_0583|M.thermoresistible__bu RTLRRVSR----
MSMEG_3867|M.smegmatis_MC2_155 RRTR--------
MAB_1908c|M.abscessus_ATCC_199 RGRRR-------
MLBr_01809|M.leprae_Br4923 RGALAGRQ----
*