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MHRNRRLAITAITAITAVATLGVAGCSPSPDNAESSTSAVAPAPPAAPSALPVPPSAPLPPPEALVDVLS RLADPNIPGDKKLDLVEGSTPDTAAALDRFTTAARDGGYLPMNFAANDLAWSATNPCDVVATVVVTTAQP ENREFTVPMEFTPIHGGWQLSQRTSEMLLAPGNSRGSQTATPEPSPGPAPNPEPAPVEPAPEESPPATGS VAPSSGPPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2338 | lppK | - | 100% (219) | lipoprotein, LppK |
| M. ulcerans Agy99 | MUL_1004 | - | 9e-08 | 28.02% (182) | hypothetical protein MUL_1004 |
| M. ulcerans Agy99 | MUL_4491 | - | 6e-07 | 41.18% (51) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2140 | lppK | 4e-58 | 58.85% (192) | lipoprotein lppK |
| M. gilvum PYR-GCK | Mflv_3067 | - | 5e-36 | 44.81% (183) | hypothetical protein Mflv_3067 |
| M. tuberculosis H37Rv | Rv2116 | lppK | 4e-58 | 58.85% (192) | lipoprotein lppK |
| M. leprae Br4923 | MLBr_01315 | - | 2e-46 | 49.21% (189) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_2160c | - | 1e-37 | 41.92% (198) | putative lipoprotein LppK precursor |
| M. marinum M | MMAR_3092 | lppK | 1e-119 | 98.12% (213) | lipoprotein, LppK |
| M. avium 104 | MAV_2399 | - | 2e-57 | 55.84% (197) | LppK protein |
| M. smegmatis MC2 155 | MSMEG_3904 | - | 8e-38 | 42.93% (191) | LppK protein |
| M. thermoresistible (build 8) | TH_0235 | - | 3e-35 | 45.93% (172) | LppK protein |
| M. vanbaalenii PYR-1 | Mvan_3460 | - | 8e-42 | 46.11% (180) | putative lipoprotein LppK |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3067|M.gilvum_PYR-GCK ---------------------------MSGCSQSEHPAATPSTPPP--AA
Mvan_3460|M.vanbaalenii_PYR-1 --------------MVRSAVTFVAALGLCGCNQNEHPAATAPSPAPPAVE
MUL_2338|M.ulcerans_Agy99 -----MHRNRRLAITAITAITAVATLGVAGCSPSPDNAESSTSAVAPAPP
MMAR_3092|M.marinum_M -----------MAITAITAITAVATLGVAGCSPSPDNAESSTSAVAPAPP
Mb2140|M.bovis_AF2122/97 --------MRRNIRVTLGAATIVAALGLSGCSHP--EFKRSSPPAPSLPP
Rv2116|M.tuberculosis_H37Rv --------MRRNIRVTLGAATIVAALGLSGCSHP--EFKRSSPPAPSLPP
MAV_2399|M.avium_104 ----------------MSAATALAAVGLAACSTS--HPRSETSAASSLPP
MLBr_01315|M.leprae_Br4923 ----MSRWTHRTFFIALSAIVTTAGFGSSGCAHG--NSSTSESAVPSTFP
MSMEG_3904|M.smegmatis_MC2_155 -------MNRNRIAVLSAATVTVAALGLSGCGGD-DRQADKPVTVPSTSA
TH_0235|M.thermoresistible__bu ----------------------VAALGLAGCGPQPESRTGDHTGAQQVRP
MAB_2160c|M.abscessus_ATCC_199 MGVTWIMVHHRLVARLVVLAAGAAVFALSACSSSSDKASPTSSSAPQSTA
..*
Mflv_3067|M.gilvum_PYR-GCK STAHPDPIPDSRGGPPLPPATALTDVMARLTDPAVPGDEKVTLIADGTAA
Mvan_3460|M.vanbaalenii_PYR-1 SSAPAAPIPDSPGGPPLPPPDALIGVMARLSDPAVPGDQKITLIENASQG
MUL_2338|M.ulcerans_Agy99 AAPSALPVPPSA---PLPPPEALVDVLSRLADPNIPGDKKLDLVEGSTPD
MMAR_3092|M.marinum_M AAPSALPVPPAA---PLPPPEALVDVLSRLADPNIPGDKKLDLVEGSTPD
Mb2140|M.bovis_AF2122/97 VTSSPLEAAPIT---PLPAPEALIDVLSRLADPAVPGTNKVQLIEGATPE
Rv2116|M.tuberculosis_H37Rv VTSSPLEAAPIT---PLPAPEALIDVLSRLADPAVPGTNKVQLIEGATPE
MAV_2399|M.avium_104 ATSTPIAPPATT---PLPPPEALTDVLGRLADPSVPGANKVSLVEGATPE
MLBr_01315|M.leprae_Br4923 GISSSITAPPAT---GLPAPEVLTNVLSRLADPNIPGIDKLPLIESATPD
MSMEG_3904|M.smegmatis_MC2_155 VVTTP-APPPAH---PLPAPEALTGVLYRLADVNVPGAEKVGLVEQATPD
TH_0235|M.thermoresistible__bu SMAAP-PPPAAA---PLPAPEALTDVLYRLADAAVPGAEKTAAVQKATPA
MAB_2160c|M.abscessus_ATCC_199 SSAAAAAAPDHP----LPDPAALTDVLNRLADPNLPGAEKVTAVQGATP-
. . . ** . .* .*: **:* :** .* : .:
Mflv_3067|M.gilvum_PYR-GCK EAGALDRFAAALRDNGSLPLTIEARDLAWSQSAPGNVIATVVIRSANPQT
Mvan_3460|M.vanbaalenii_PYR-1 EAAGLDRFAVALRDNGSLPLTFEARDLAWSQSEPGNVVATIVITPANPPG
MUL_2338|M.ulcerans_Agy99 TAAALDRFTTAARDGGYLPMNFAANDLAWSATNPCDVVATVVVTTAQPEN
MMAR_3092|M.marinum_M TAAALDRFTTAARDGGYLPMNFAANDLAWSATNPSDVVATVVVTTAQPEN
Mb2140|M.bovis_AF2122/97 NAAALDRFTTALRDGSYLPMTFAANDIAWSDNKPSDVMATVVVTTAHPDN
Rv2116|M.tuberculosis_H37Rv NAAALDRFTTALRDGSYLPMTFAANDIAWSDNKPSDVMATVVVTTAHPDN
MAV_2399|M.avium_104 SAATLDKFTNALRDNGYLPMTFTANDIAWSDQNPSNVKASIAVHTNQPNN
MLBr_01315|M.leprae_Br4923 SAVTLDKFSNALRDNGYLPMTFTANNIAWSNKNPSDVLATISVNIAQTNN
MSMEG_3904|M.smegmatis_MC2_155 DAEALDKFGRALADNGFTPLNFEATDLAWSENDSRNVIATIHVTAGEGDA
TH_0235|M.thermoresistible__bu DAEGLDRFARALRDGGYQPVTFAAADLMWSDTEADRVVATITATGPDPDT
MAB_2160c|M.abscessus_ATCC_199 --EQLDKFTKAIGDAGFSPLSFTVKDPKWSTETPGDVEAVVTINSPSPKM
**:* * * . *:.: . : ** . * * :
Mflv_3067|M.gilvum_PYR-GCK G-EFTYPMEFVSADG---VWQLTRGTADVLLTLDPA------PSPPPPGP
Mvan_3460|M.vanbaalenii_PYR-1 G-QFTYPMEFAPSDG---SWQLTRQTADLLLQLD----------------
MUL_2338|M.ulcerans_Agy99 R-EFTVPMEFTPIHG---GWQLSQRTSEMLLAPGNSRGSQTATPEPSPGP
MMAR_3092|M.marinum_M R-EFTFPMEFTPIHG---GWQLSQRTSEMLLALGNSRGSQTATPEPSPGP
Mb2140|M.bovis_AF2122/97 R-EFTFPMEFVSFKG---GWQLSRQTAEMLLAMGNS-------PDSTPSA
Rv2116|M.tuberculosis_H37Rv R-EFTFPMEFVSFKG---GWQLSRQTAEMLLAMGNS-------PDSTPSA
MAV_2399|M.avium_104 A-NFTFPMEFTPFQG---GWQLSRHTAETLLALGKS-------PQAPTSA
MLBr_01315|M.leprae_Br4923 S-VFSFPMEFTPFPPPQQSWQLSKRTADMLLEFGNS-----------SGL
MSMEG_3904|M.smegmatis_MC2_155 PGQFTFPMEFTPKGP---DWQLTRNTADMLLEMGAA---------AGGGQ
TH_0235|M.thermoresistible__bu N-TFSFPMEFTTDAHG--NWQLTRETADTLLEMG----------------
MAB_2160c|M.abscessus_ATCC_199 G-GFAVPMSFSPEGE---GWKLSKRTSDLLLKTGTSLAGTGTPKEAPPAD
*: **.* . *:*:: *:: ** .
Mflv_3067|M.gilvum_PYR-GCK PP---------------------PPAPEPPR
Mvan_3460|M.vanbaalenii_PYR-1 -----------------------DPAPSPPR
MUL_2338|M.ulcerans_Agy99 APNPEPAPVEPAPEESPPATGSVAPSSGPPG
MMAR_3092|M.marinum_M APNPEPAPVEPAPEESPPATGSVAPSSGPPG
Mb2140|M.bovis_AF2122/97 TS---------------PAP---APSPTPPG
Rv2116|M.tuberculosis_H37Rv TS---------------PAP---APSPTPPG
MAV_2399|M.avium_104 APEGPGAPAPPAEPAPPPEP---APTQTPPG
MLBr_01315|M.leprae_Br4923 TN---------------PAP-IKAPTPTPSH
MSMEG_3904|M.smegmatis_MC2_155 SE--------------------PATTPTPTP
TH_0235|M.thermoresistible__bu ----------------------PAESPTPPR
MAB_2160c|M.abscessus_ATCC_199 APSP------------------QAPAPTP--
: *