For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRRNIRVTLGAATIVAALGLSGCSHPEFKRSSPPAPSLPPVTSSPLEAAPITPLPAPEALIDVLSRLADP AVPGTNKVQLIEGATPENAAALDRFTTALRDGSYLPMTFAANDIAWSDNKPSDVMATVVVTTAHPDNREF TFPMEFVSFKGGWQLSRQTAEMLLAMGNSPDSTPSATSPAPAPSPTPPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2116 | lppK | - | 100% (189) | Probable conserved lipoprotein lppK |
| M. tuberculosis H37Rv | Rv2376c | cfp2 | 3e-08 | 29.63% (162) | low molecular weight antigen CFP2 (low molecular weight |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2140 | lppK | 1e-107 | 100.00% (189) | lipoprotein lppK |
| M. gilvum PYR-GCK | Mflv_3067 | - | 1e-39 | 48.26% (172) | hypothetical protein Mflv_3067 |
| M. leprae Br4923 | MLBr_01315 | - | 3e-48 | 50.80% (187) | putative lipoprotein |
| M. abscessus ATCC 19977 | MAB_2160c | - | 2e-32 | 43.09% (181) | putative lipoprotein LppK precursor |
| M. marinum M | MMAR_3092 | lppK | 2e-59 | 62.01% (179) | lipoprotein, LppK |
| M. avium 104 | MAV_2399 | - | 1e-59 | 60.00% (185) | LppK protein |
| M. smegmatis MC2 155 | MSMEG_3904 | - | 7e-39 | 48.42% (190) | LppK protein |
| M. thermoresistible (build 8) | TH_0235 | - | 1e-37 | 48.88% (178) | LppK protein |
| M. ulcerans Agy99 | MUL_2338 | lppK | 3e-58 | 58.85% (192) | lipoprotein, LppK |
| M. vanbaalenii PYR-1 | Mvan_3460 | - | 2e-43 | 50.59% (170) | putative lipoprotein LppK |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3067|M.gilvum_PYR-GCK ---------------------------MSGCSQSEHPAATPSTPPP--AA
Mvan_3460|M.vanbaalenii_PYR-1 --------------MVRSAVTFVAALGLCGCNQNEHPAATAPSPAPPAVE
Rv2116|M.tuberculosis_H37Rv --------MRRNIRVTLGAATIVAALGLSGCSHP--EFKRSSPPAPSLPP
Mb2140|M.bovis_AF2122/97 --------MRRNIRVTLGAATIVAALGLSGCSHP--EFKRSSPPAPSLPP
MAV_2399|M.avium_104 ----------------MSAATALAAVGLAACSTS--HPRSETSAASSLPP
MMAR_3092|M.marinum_M -----------MAITAITAITAVATLGVAGCSPSPDNAESSTSAVAPAPP
MUL_2338|M.ulcerans_Agy99 -----MHRNRRLAITAITAITAVATLGVAGCSPSPDNAESSTSAVAPAPP
MLBr_01315|M.leprae_Br4923 ----MSRWTHRTFFIALSAIVTTAGFGSSGCAHG--NSSTSESAVPSTFP
MSMEG_3904|M.smegmatis_MC2_155 -------MNRNRIAVLSAATVTVAALGLSGCGGD-DRQADKPVTVPSTSA
TH_0235|M.thermoresistible__bu ----------------------VAALGLAGCGPQPESRTGDHTGAQQVRP
MAB_2160c|M.abscessus_ATCC_199 MGVTWIMVHHRLVARLVVLAAGAAVFALSACSSSSDKASPTSSSAPQSTA
..*
Mflv_3067|M.gilvum_PYR-GCK STAHPDPIPDSRGGPPLPPATALTDVMARLTDPAVPGDEKVTLIADGTAA
Mvan_3460|M.vanbaalenii_PYR-1 SSAPAAPIPDSPGGPPLPPPDALIGVMARLSDPAVPGDQKITLIENASQG
Rv2116|M.tuberculosis_H37Rv VTSSPLEAAPIT---PLPAPEALIDVLSRLADPAVPGTNKVQLIEGATPE
Mb2140|M.bovis_AF2122/97 VTSSPLEAAPIT---PLPAPEALIDVLSRLADPAVPGTNKVQLIEGATPE
MAV_2399|M.avium_104 ATSTPIAPPATT---PLPPPEALTDVLGRLADPSVPGANKVSLVEGATPE
MMAR_3092|M.marinum_M AAPSALPVPPAA---PLPPPEALVDVLSRLADPNIPGDKKLDLVEGSTPD
MUL_2338|M.ulcerans_Agy99 AAPSALPVPPSA---PLPPPEALVDVLSRLADPNIPGDKKLDLVEGSTPD
MLBr_01315|M.leprae_Br4923 GISSSITAPPAT---GLPAPEVLTNVLSRLADPNIPGIDKLPLIESATPD
MSMEG_3904|M.smegmatis_MC2_155 VVTTP-APPPAH---PLPAPEALTGVLYRLADVNVPGAEKVGLVEQATPD
TH_0235|M.thermoresistible__bu SMAAP-PPPAAA---PLPAPEALTDVLYRLADAAVPGAEKTAAVQKATPA
MAB_2160c|M.abscessus_ATCC_199 SSAAAAAAPDHP----LPDPAALTDVLNRLADPNLPGAEKVTAVQGATP-
. . . ** . .* .*: **:* :** .* : .:
Mflv_3067|M.gilvum_PYR-GCK EAGALDRFAAALRDNGSLPLTIEARDLAWSQSAPGNVIATVVIRSANPQT
Mvan_3460|M.vanbaalenii_PYR-1 EAAGLDRFAVALRDNGSLPLTFEARDLAWSQSEPGNVVATIVITPANPPG
Rv2116|M.tuberculosis_H37Rv NAAALDRFTTALRDGSYLPMTFAANDIAWSDNKPSDVMATVVVTTAHPDN
Mb2140|M.bovis_AF2122/97 NAAALDRFTTALRDGSYLPMTFAANDIAWSDNKPSDVMATVVVTTAHPDN
MAV_2399|M.avium_104 SAATLDKFTNALRDNGYLPMTFTANDIAWSDQNPSNVKASIAVHTNQPNN
MMAR_3092|M.marinum_M TAAALDRFTTAARDGGYLPMNFAANDLAWSATNPSDVVATVVVTTAQPEN
MUL_2338|M.ulcerans_Agy99 TAAALDRFTTAARDGGYLPMNFAANDLAWSATNPCDVVATVVVTTAQPEN
MLBr_01315|M.leprae_Br4923 SAVTLDKFSNALRDNGYLPMTFTANNIAWSNKNPSDVLATISVNIAQTNN
MSMEG_3904|M.smegmatis_MC2_155 DAEALDKFGRALADNGFTPLNFEATDLAWSENDSRNVIATIHVTAGEGDA
TH_0235|M.thermoresistible__bu DAEGLDRFARALRDGGYQPVTFAAADLMWSDTEADRVVATITATGPDPDT
MAB_2160c|M.abscessus_ATCC_199 --EQLDKFTKAIGDAGFSPLSFTVKDPKWSTETPGDVEAVVTINSPSPKM
**:* * * . *:.: . : ** . * * :
Mflv_3067|M.gilvum_PYR-GCK G-EFTYPMEFVSADG---VWQLTRGTADVLLTLDPA------PSPPPPGP
Mvan_3460|M.vanbaalenii_PYR-1 G-QFTYPMEFAPSDG---SWQLTRQTADLLLQLD----------------
Rv2116|M.tuberculosis_H37Rv R-EFTFPMEFVSFKG---GWQLSRQTAEMLLAMGNS-------PDSTPSA
Mb2140|M.bovis_AF2122/97 R-EFTFPMEFVSFKG---GWQLSRQTAEMLLAMGNS-------PDSTPSA
MAV_2399|M.avium_104 A-NFTFPMEFTPFQG---GWQLSRHTAETLLALGKS-------PQAPTSA
MMAR_3092|M.marinum_M R-EFTFPMEFTPIHG---GWQLSQRTSEMLLALGNSRGSQTATPEPSPGP
MUL_2338|M.ulcerans_Agy99 R-EFTVPMEFTPIHG---GWQLSQRTSEMLLAPGNSRGSQTATPEPSPGP
MLBr_01315|M.leprae_Br4923 S-VFSFPMEFTPFPPPQQSWQLSKRTADMLLEFGNS-----------SGL
MSMEG_3904|M.smegmatis_MC2_155 PGQFTFPMEFTPKGP---DWQLTRNTADMLLEMGAA---------AGGGQ
TH_0235|M.thermoresistible__bu N-TFSFPMEFTTDAHG--NWQLTRETADTLLEMG----------------
MAB_2160c|M.abscessus_ATCC_199 G-GFAVPMSFSPEGE---GWKLSKRTSDLLLKTGTSLAGTGTPKEAPPAD
*: **.* . *:*:: *:: ** .
Mflv_3067|M.gilvum_PYR-GCK PP---------------------PPAPEPPR
Mvan_3460|M.vanbaalenii_PYR-1 -----------------------DPAPSPPR
Rv2116|M.tuberculosis_H37Rv TS---------------PAP---APSPTPPG
Mb2140|M.bovis_AF2122/97 TS---------------PAP---APSPTPPG
MAV_2399|M.avium_104 APEGPGAPAPPAEPAPPPEP---APTQTPPG
MMAR_3092|M.marinum_M APNPEPAPVEPAPEESPPATGSVAPSSGPPG
MUL_2338|M.ulcerans_Agy99 APNPEPAPVEPAPEESPPATGSVAPSSGPPG
MLBr_01315|M.leprae_Br4923 TN---------------PAP-IKAPTPTPSH
MSMEG_3904|M.smegmatis_MC2_155 SE--------------------PATTPTPTP
TH_0235|M.thermoresistible__bu ----------------------PAESPTPPR
MAB_2160c|M.abscessus_ATCC_199 APSP------------------QAPAPTP--
: *