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TCGVVISGCAIASAIVLASMVARVASDPSARCLRCWLGSLLMLSALWALRAVTHWLQARLGQPGASAVIA ELSGQVLESVTARQPNELAAQRDAAAVVVTRGLDGLRPYFTGYLPTLFLAAILTPATVVMIAVYDVKSAL IAVITLPPIPVFMVLIGLATAERSAAALAAMATLQARLLDLIAGIPTLRALDRASGPEQRIAELSAAHRR SALATLRIAFLSAPVLELLATLGVAVIAVSIGLRLVFGEMTLTAGLTVLLLTPDVYWPLRRIGVEFHAAQ DGKSAADQAFTLIGETACTPPARRAVTARGATIHLQNLSVTGRDGRSPHNLTATIEPGQVTVLTGQNGAG KSTTLQLIAGLTTPSNGRLTVAGIDISELDPVDWWRQLSWLPQRSVLIPGTVRDNLVLLGEPADLDSACA ASGFDAVLAELPDGLDTVLGRDGVGLSLGQRQRLALARVLGSPSPVLLLDEPTAHLDSRTGEQVLQAIAE RARTGATVVVVGHREPVVAICDQVVEVTRDGLDTQAGYVPV*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_1602 | cydD | - | 100% (532) | component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD |
M. ulcerans Agy99 | MUL_4011 | - | 1e-35 | 24.75% (505) | transmembrane ATP-binding protein ABC transporter |
M. ulcerans Agy99 | MUL_1345 | - | 2e-32 | 27.63% (503) | drugs-transport transmembrane ATP-binding protein ABC |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1647c | cydD | 0.0 | 74.81% (524) | cytochrome' transport transmembrane ATP-binding protein ABC |
M. gilvum PYR-GCK | Mflv_3587 | - | 1e-175 | 61.17% (515) | ABC transporter, transmembrane region, type 1 |
M. tuberculosis H37Rv | Rv1621c | cydD | 0.0 | 74.81% (524) | cytochrome' transport transmembrane ATP-binding protein ABC |
M. leprae Br4923 | MLBr_01113 | - | 5e-31 | 22.11% (502) | putative ABC transporter, ATP-binding component |
M. abscessus ATCC 19977 | MAB_2632 | - | 1e-160 | 56.13% (522) | ABC transporter ATP-binding protein |
M. marinum M | MMAR_2424 | cydD | 0.0 | 98.12% (532) | cytochrome transmembrane ATP-binding protein ABC transporter |
M. avium 104 | MAV_3166 | cydD | 0.0 | 74.62% (524) | ABC transporter, CydDC cysteine exporter (CydDC-E) family |
M. smegmatis MC2 155 | MSMEG_3231 | cydD | 1e-168 | 61.67% (514) | ABC transporter, CydDC cysteine exporter (CydDC-E) family |
M. thermoresistible (build 8) | TH_2470 | - | 1e-176 | 62.98% (524) | PUTATIVE ABC transporter, transmembrane region, type 1 |
M. vanbaalenii PYR-1 | Mvan_2828 | - | 1e-172 | 62.21% (516) | ABC transporter, transmembrane region, type 1 |
CLUSTAL 2.0.9 multiple sequence alignment MUL_1602|M.ulcerans_Agy99 -----------------------------------MTCGVVISGCAIAS- MMAR_2424|M.marinum_M -----------------------------------MTCGVVISGCAIAS- Mb1647c|M.bovis_AF2122/97 -----------------------------------MACGVGISGCAIGS- Rv1621c|M.tuberculosis_H37Rv -----------------------------------MACGVGISGCAIGS- MAV_3166|M.avium_104 ---------------------------MRRYLVAAVGCGVLISGCAIGS- MSMEG_3231|M.smegmatis_MC2_155 ---------------------------------------MVIAGCTIAS- TH_2470|M.thermoresistible__bu ---------------------------MRRYLAASVAASTVIAAATIGS- Mflv_3587|M.gilvum_PYR-GCK ---------------------------MRRFLAATTAYGVLIAACTIAS- Mvan_2828|M.vanbaalenii_PYR-1 ---------------------------MRRFLIATTACGVLIAACTIAS- MAB_2632|M.abscessus_ATCC_1997 --------MTRPRGAPVDPRLWRRSAPARRYLFLTVLCELVMTGCTLVI- MLBr_01113|M.leprae_Br4923 MTMATAPATRSCDFYCTIRRLLKQLVPQRRLSLTVITLGITGTAIGIIVP :. : MUL_1602|M.ulcerans_Agy99 -------AIVLASMVARVAS--DPSARCLRCWLGS--------------- MMAR_2424|M.marinum_M -------AIVLASMVARVAS--DPSARCLRCWLGS--------------- Mb1647c|M.bovis_AF2122/97 -------AIVLASIVAGVIDPANPGMAGLRRWLGP--------------- Rv1621c|M.tuberculosis_H37Rv -------AIVLASIVAGVIDPANPGMAGLRRWLGP--------------- MAV_3166|M.avium_104 -------AVVLAGIVARVVG--DTSAGEMRSWPAP--------------- MSMEG_3231|M.smegmatis_MC2_155 -------AVVLAHIVAGIITNPATALGGETDWAPG--------------- TH_2470|M.thermoresistible__bu -------AVVLAGIVAGVITDPATRT--VAYWSDQ--------------- Mflv_3587|M.gilvum_PYR-GCK -------AVVLASLVARVVTDPVSRS--VEALAAP--------------- Mvan_2828|M.vanbaalenii_PYR-1 -------AVVLAGIVARVITDPASRS--VGELSTP--------------- MAB_2632|M.abscessus_ATCC_1997 -------AIVLAQALSQLITNPAARD--LPHMWQP--------------- MLBr_01113|M.leprae_Br4923 WVLGHTTDLLFNGVIGRQLPKGISKTQAVAAARTRGDNALADLLSGMNLV ::: :. . MUL_1602|M.ulcerans_Agy99 -------------LLMLSALWALRAVTHWLQARLGQPGASAVIAELSGQV MMAR_2424|M.marinum_M -------------LLILSALWALRAVTHWLQARLGQRGASAVIAELSGQV Mb1647c|M.bovis_AF2122/97 -------------LSILLVLWGLRASIQWLQARLAQRGASAVIADLSGQV Rv1621c|M.tuberculosis_H37Rv -------------LSILLVLWGLRASIQWLQARLAQRGASAVIADLSGQV MAV_3166|M.avium_104 -------------LSILLALWAVRAVAHWLQARLGQRGASAVIADLSGQV MSMEG_3231|M.smegmatis_MC2_155 -------------LVALAVLWSVRVVAQWFQGRLSQRGATAVIGELSRQV TH_2470|M.thermoresistible__bu -------------LALLTGLWLIRTGAHWQQGRLSQRGATAVIAELSSKV Mflv_3587|M.gilvum_PYR-GCK -------------LAILVSLWTVRVLAHWQQGRVAQHGASAVIADLTDQV Mvan_2828|M.vanbaalenii_PYR-1 -------------IAILLALWVFRALAQWRQGRLGQHGASAVIADLSDQV MAB_2632|M.abscessus_ATCC_1997 -------------IILLSALWALRALAHGVQVRFSERGATGVIADLDDQL MLBr_01113|M.leprae_Br4923 PGQGVDFVAVGRTLGLALSLYLVYTLLTWAQARLLNVTVQRIMFALRSDV : *: . . * *. : . :: * .: MUL_1602|M.ulcerans_Agy99 LESVTARQPNELAAQ-RDAAAVVVTRGLDGLRPYFTGYLPTLFLAAILTP MMAR_2424|M.marinum_M LESVTARQPNELAAQ-RDAAAVVVTRGLDGLRPYFTGYLPTLFLAAILTP Mb1647c|M.bovis_AF2122/97 LTAVTARRPSQLAAQ-RDAAAVLITRGLDGLRPYFTGYLPTLLLAAILTP Rv1621c|M.tuberculosis_H37Rv LTAVTARRPSQLAAQ-RDAAAVLITRGLDGLRPYFTGYLPTLLLAAILTP MAV_3166|M.avium_104 LAAVTARPPAELAAQ-RDEAAVVVTRGLDGLRPYFTGYLPTLMLAAILTP MSMEG_3231|M.smegmatis_MC2_155 LSSVTTSSPRRLAAD-RDSAAAVVTRGLDGLRPYFTGYLPAVVLAGILTP TH_2470|M.thermoresistible__bu LRTVTAAAPRDLAAA-RDRAAAVVTRGLDGLRPYFTGYLPTLFSAGILTP Mflv_3587|M.gilvum_PYR-GCK LRAATSLPPRELATR-RDEAAVVITRGLDGLRVYFTAYLPSLLLAVLLTP Mvan_2828|M.vanbaalenii_PYR-1 LTTATSLPPRQLAAH-RDEAAVVITRGLDGLRVYFTTYLPSLFLAAVLTP MAB_2632|M.abscessus_ATCC_1997 LSAVAQVQPRDLEQH-RDSATEVLTRGLDDLRPYFAGYLPALLSAAIVTP MLBr_01113|M.leprae_Br4923 EDKVHRLPLSYCDTRQRGELLSRVTNDIDNLQSSLSITLSQLLTSLLTVV . *. :*..:*.*: :: *. :. : : . MUL_1602|M.ulcerans_Agy99 ATVVMIAVYDVKSALIAVITLPPIPVFMVLIGLATAERSAAALAAMATLQ MMAR_2424|M.marinum_M ATVVMIAVYDVKSALIAVITLPLIPVFMVLIGLATAERSAAALAAMATLQ Mb1647c|M.bovis_AF2122/97 ATVAVIGLYDLKSMAIVVITLPLIPIFMVLIGLATTNPSAAALAAMTAVQ Rv1621c|M.tuberculosis_H37Rv ATVAVIGLYDLKSMAIVVITLPLIPIFMVLIGLATTNPSAAALAAMTAVQ MAV_3166|M.avium_104 ATVAVIAAYDVKSTVIVAITLPLIPIFMVLIGLATRDRSAAALAAMTTLQ MSMEG_3231|M.smegmatis_MC2_155 AALVVMAAYDWQAAAIVVIALPLIPIFMVLIGLLTAERSAAALTAMTTLQ TH_2470|M.thermoresistible__bu AAVFAIAWHDLQSAVTVLIVLPLIPLFMVLIGLTTRDHSAAALAAMTNLQ Mflv_3587|M.gilvum_PYR-GCK TTAAVIAWYDWRSAVIVAIALPLIPIFMILIGMATADRSEAALSAMTTLQ Mvan_2828|M.vanbaalenii_PYR-1 ATAVVIAFYDWKSALIVTIALPLIPVFMVLIGLATADRSAAALAAMATLQ MAB_2632|M.abscessus_ATCC_1997 AAAVVIALSDIRSALIVAITLPLIPVFMILIGLLTRDRAATALAASTAAT MLBr_01113|M.leprae_Br4923 AVLVVMVSVSPLLALVALLTVPMSLLATRAIAQRSQQLFVAQWTSAGRLN :. : . . :.:* : *. : : : :: MUL_1602|M.ulcerans_Agy99 ARLLDLIAGIPTLRALDRASGPEQRIAELSAAHRRSALATLRIAFLSAPV MMAR_2424|M.marinum_M ARLLDLIAGIPTLRALGRASGPEQRIAELSAAHRRSALATLRIAFLSALV Mb1647c|M.bovis_AF2122/97 ARLLDLIAGIPTLRALGRASGPEQRIAELSADHRRSAMATLRIAFLSALV Rv1621c|M.tuberculosis_H37Rv ARLLDLIAGIPTLRALGRASGPEQRIAELSADHRRSAMATLRIAFLSALV MAV_3166|M.avium_104 ARLLDLIAGIPTLRALGRSSGPDRSIAELAAAHRRSAMATLRIAFLSALV MSMEG_3231|M.smegmatis_MC2_155 GRMLDLIAGIPTLRAVGRAGGSVQRIAELSASHRRSTMATLRISFLSALV TH_2470|M.thermoresistible__bu NRTLDLIAGIPTLRALNRIDGSARRIAELVAAHRRSTMATLRIAFLSAFV Mflv_3587|M.gilvum_PYR-GCK SRLLDLVAGLPTLRALDRTRGAATRIAELSAAHRRSAMATMRIAFLSALV Mvan_2828|M.vanbaalenii_PYR-1 SRLLDLVAGLPTLRALGRTGGAAARIAELGAAHRRSAMATMRIAFLSALV MAB_2632|M.abscessus_ATCC_1997 GQIVDLIAGIPTLRALGRTATPLRRIAELGTAQRRSVMATLRVAFLSAMV MLBr_01113|M.leprae_Br4923 AHIEETYSGLTVVKTFGHQTAAREQFRNVNNDVYQASFSAQFFSGLVSPA : : :*:..:::..: . : :: :: ::: .: * : . MUL_1602|M.ulcerans_Agy99 LELLATLGVAVIAVSIGLRLVFGEMTLTAGLTVLLLTPDVYWPLRRIGVE MMAR_2424|M.marinum_M LELLATLGVAVIAVSIGLRLVFGEMTLTAGLTVLLLAPDVYWPLRRIGVE Mb1647c|M.bovis_AF2122/97 LELLATLGVALVAVGIGLRLVFGEMSLTAGLTVLLLAPEVYWPLRRVGVQ Rv1621c|M.tuberculosis_H37Rv LELLATLGVALVAVGIGLRLVFGEMSLTAGLTVLLLAPEVYWPLRRVGVQ MAV_3166|M.avium_104 LELLATLGVALIAVGIGLRLVFGEMTLTAGLTVLLLAPDVYWPLRRIGVE MSMEG_3231|M.smegmatis_MC2_155 LELLATLGVALVAVSVGLRLVFGDMTLAAGLTALLLAPEVFWPLRRVGAA TH_2470|M.thermoresistible__bu LELLATLSVALVAVGIGLRLVYGEMTLTAGLTALLLAPEVFWPLRRIGVE Mflv_3587|M.gilvum_PYR-GCK LELLATLGVALVAVGVGMRLVFGDMTLTAGLTALLLAPEAFWPLRRVGAA Mvan_2828|M.vanbaalenii_PYR-1 LELLATLGVALVAVGVGMRLVYGEMTLSAGLTALLLAPEVFWPLRRVGAA MAB_2632|M.abscessus_ATCC_1997 LEMIATLSVALIAVSIGMRLVFGHLDLTTALTVLILAPEVYWPLRRVGIQ MLBr_01113|M.leprae_Br4923 TMFISNLGYVVVAALGGLQVATGHITLGNIQAFIQYVRQFNMPLSQVAGI :::.*. .::*. *:::. *.: * : : . : ** ::. MUL_1602|M.ulcerans_Agy99 FHAAQDGKSAADQAFTLIGETACTPPAR-------RAVTARGATIHLQNL MMAR_2424|M.marinum_M FHAAQDGKSAADQAFTLIGETACTPPAR-------RAVTARGATIHLQNL Mb1647c|M.bovis_AF2122/97 FHAAADGRTAADKAFALLGESPSPTPGR-------RTVTARGGVIRLERL Rv1621c|M.tuberculosis_H37Rv FHAAADGRTAADKAFALLGESPSPTPGR-------RTVTARGGVIRLERL MAV_3166|M.avium_104 FHAAQDGRTAAGAAFALIGEPGGPSAAKVRT----RTVTARGAPIRLEHL MSMEG_3231|M.smegmatis_MC2_155 FHAAQDGKTAAEQALRLC-AEPHPPTGH-------EVVPAGAPVIEVP-- TH_2470|M.thermoresistible__bu FHAAQDGKAAADKAFELLDAAPRPAGGT-------RVVEAAGATIEVD-- Mflv_3587|M.gilvum_PYR-GCK FHSAQDGKTAVEAAFRFLDDAPASPAGT-------RAIPDHPLTVEVD-- Mvan_2828|M.vanbaalenii_PYR-1 FHSAQDGKTALQAAFRFIDTAEPPGAGT-------LGVPGDSVTVEVD-- MAB_2632|M.abscessus_ATCC_1997 FHSAADGTAAADRAFELLDTLTPSMPGPVAAP---VQAPPRRPTIGLEAI MLBr_01113|M.leprae_Br4923 YNTLQSGLASAERVFDLLDEPEELPDPMLALPPPHGQVPRINGRVEFQQV ::: .* :: .: : : . MUL_1602|M.ulcerans_Agy99 SVTGRDGR-SPHNLTATIEPGQVTVLTGQNGAGKSTTLQLIAGLTTPSNG MMAR_2424|M.marinum_M SVTGRDGR-SPHNLTATIEPGQVTVLTGQNGAGKSTTLQLIAGLTTPSNG Mb1647c|M.bovis_AF2122/97 SVRGRDGR-APYDLTADIEPGRVTVLTGRNGAGKSTTLQAIAGLTAPSSG Rv1621c|M.tuberculosis_H37Rv SVRGRDGR-APYDLTADIEPGRVTVLTGRNGAGKSTTLQAIAGLTAPSSG MAV_3166|M.avium_104 SVAGRDGQ-APCDLSAVIEPGAVTVLTGRNGAGKSTTLQAIAGITAPSSG MSMEG_3231|M.smegmatis_MC2_155 ------------ALKAVMEPGRVTVLTGPNGVGKSTLLQAILGLQESPCG TH_2470|M.thermoresistible__bu ------------ALTADLGPGCVTVLTGPNGVGKSSVLHTVLGLAPPLSG Mflv_3587|M.gilvum_PYR-GCK ------------DPALTAEPGRVTVLTGPNGAGKSTLLQAILGLGPPPTG Mvan_2828|M.vanbaalenii_PYR-1 ------------DPELTAGPGRVTVLTGPNGIGKSTLLQAILGLDRPTGG MAB_2632|M.abscessus_ATCC_1997 SVLDRGGY-APWELTATIRPGAVTVLTGHNGAGKSTALHAITGLAVPATG MLBr_01113|M.leprae_Br4923 SFAYRTGTPVIDDLSMVVEPGSTVAIVGPTGAGKTTLVNLLMRFYDVDSG ** ...:.* .* **:: :: : : * MUL_1602|M.ulcerans_Agy99 RLTVAGIDISELDPVDWWRQLSWLPQRSVLIPGTVRDNLVLLGEPA---D MMAR_2424|M.marinum_M RLTIAGIDISELDPVDWWRQLSWLPQRSVLIPGTVRDNLVLLGEPA---D Mb1647c|M.bovis_AF2122/97 RITVAGVDVTNLAPAAWWRQLSWLPQRPVLVPGTVRHNLVLLGPVD---D Rv1621c|M.tuberculosis_H37Rv RITVAGVDVTNLAPAAWWRQLSWLPQRPVLVPGTVRHNLVLLGPVD---D MAV_3166|M.avium_104 RVTVGGVDVADLAPRGWWAQLSWLPQRPVLVPGTVDENLRLFGELD---D MSMEG_3231|M.smegmatis_MC2_155 PILVAGVEVGALDRSAWWGRLAWMPHRPVLVPGTVRENLELLGPVP---G TH_2470|M.thermoresistible__bu SVRVGGVDIGELDLPAWWRQIAWLPHRPVLIPGTVRDNLSLFGPLE---D Mflv_3587|M.gilvum_PYR-GCK RIRVDGVEVAELDLRQWWTRVAWLAQRPVLIPGTVRDNLELFGPLP---D Mvan_2828|M.vanbaalenii_PYR-1 GIRINGVEVAELDPQQWWPKVAWLAQRPVLIPGTVQENLELFGPLP---D MAB_2632|M.abscessus_ATCC_1997 RVLLDGMTLEQIERDTWWSMIGWLPQRPVLIPGTVRENLEIFGQLE---D MLBr_01113|M.leprae_Br4923 QILIDGVDITTVSRHALRSRIGMVLQDAWLFDGTIAENIAYGRPQASEDE : : *: : : :. : : . *. **: .*: MUL_1602|M.ulcerans_Agy99 LDSACAASGFDAVLAELPDGLDTVLGRDGVGLSLGQRQRLALARVLGSPS MMAR_2424|M.marinum_M LDSACTASGFDAVLAELPDGLDTVLGRDGVGLSLGQRQRLALARVLGSPS Mb1647c|M.bovis_AF2122/97 LERACAAAGFDAVLDELPRGLDTVLGRGGVGLSLGQRQRLGLARALGSPA Rv1621c|M.tuberculosis_H37Rv LERACAAAGFDAVLDELPRGLDTVLGRGGVGLSLGQRQRLGLARALGSPA MAV_3166|M.avium_104 IETACAIAGFDTVLAELPDAGATLLGRGGVGLSLGQRQRLGLARALGSRA MSMEG_3231|M.smegmatis_MC2_155 LDEVCRSVGFDEVLGELPDGSETPLGRGGVGLSLGQRQRLGLVRALGAPA TH_2470|M.thermoresistible__bu PENAFRRSGFDEVLAALPDGMDTPLGRDGVGLSLGQRQRLGLARALGSPA Mflv_3587|M.gilvum_PYR-GCK LESACRAACFDEVLATLPDGADTVIGRGGVGLSLGQRQRLGLARVLGSPA Mvan_2828|M.vanbaalenii_PYR-1 LRSACRAACFDEVLATLPDGLQTVIGRGGVGLSLGQRQRLGLVRVLGSAA MAB_2632|M.abscessus_ATCC_1997 LESALADSQFDTVVAALPHGLDTRLGTGGAGLSLGERQRLSLARVLGTNR MLBr_01113|M.leprae_Br4923 VMEAAKAAYVDRFVHTLSAGYQTRVSGDGDNISAGEKQLITIARAFLARP . .* .: *. . * :. .* .:* *::* : :.*.: : MUL_1602|M.ulcerans_Agy99 PVLLLDEPTAHLDSRTGEQVLQAIAERARTGATVVVVGHREPVVAICDQV MMAR_2424|M.marinum_M PVLLLDEPTAHLDSRTEEQVLQAIAERARTGATVVVVGHREPVVAIGDQV Mb1647c|M.bovis_AF2122/97 AVLLLDEPTAHLDARTEQHVLGAIVERARAGATVLVVAHRQQVAAAGDRV Rv1621c|M.tuberculosis_H37Rv AVLLLDEPTAHLDARTEQHVLGAIVERARAGATVLVVAHRQQVAAAGDRV MAV_3166|M.avium_104 AVLLLDEPTAHLDAGTEERVLRAVVERARAGATVVVVGHREPVLAIGDRV MSMEG_3231|M.smegmatis_MC2_155 DVLLLDEPTAHLDGALEDRVLAAIVARARAGATVVMVGHRAPVLAAADHV TH_2470|M.thermoresistible__bu PVLLLDEPTAHLDAAMEARVLAAITDRARAGATVVVVGHREPVLSIADRV Mflv_3587|M.gilvum_PYR-GCK AVLLFDEPTAHLDGPTEARVLAAIARRAADGATVIVVGHRDPVLAIGDVV Mvan_2828|M.vanbaalenii_PYR-1 PLLLFDEPTAHLDGPTEARVLDAITRRAADGATVVVVGHRDPILEIGDAV MAB_2632|M.abscessus_ATCC_1997 PILLLDEPTAHLDADTEAAVLAALVSRARQGATVVLVGHRAPVLAAADEI MLBr_01113|M.leprae_Br4923 QLLILDEATSSIDTRTEALIARATHDLLQD-RTSFIIAHHLPTIRDADHI :*::**.*: :* : * * .::.*: * : MUL_1602|M.ulcerans_Agy99 VEVTRDGLDTQAGYVPV------------- MMAR_2424|M.marinum_M VEVTRDGLDTQAGYVPV------------- Mb1647c|M.bovis_AF2122/97 VEVNSDGFRR-------------------- Rv1621c|M.tuberculosis_H37Rv VEVNSDGFRR-------------------- MAV_3166|M.avium_104 VAVSADRGARCAAA---------------- MSMEG_3231|M.smegmatis_MC2_155 VTMESSLVAP-------------------- TH_2470|M.thermoresistible__bu VYLKEAAADAALAHR--------------- Mflv_3587|M.gilvum_PYR-GCK VDMGGARVPS-------------------- Mvan_2828|M.vanbaalenii_PYR-1 VRMGGARVAP-------------------- MAB_2632|M.abscessus_ATCC_1997 FTVQARHAANL------------------- MLBr_01113|M.leprae_Br4923 LVVAAGKIVEQGSHAKLLARRGAYYRMTQA . :