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VSDLVQVERNGPVTTVIINRPQARNAVNGPTAAALYSAFAEFDRDESASVAVLCGNGGTFCAGADLKAFG TAEANAVHRTGPGPMGRSRMMLSKPVIAAVSGYAVAGGLELALWCDLRVAEQDSVFGVFCRRWGVPLIDG GTVRLPRLIGHSRAMDMILTGRAVQADEALAIGLANRVVPNGQARQAAEELAAQLAALPQQCLRSDRLSA LQQWGLPESAALDLEFASISRVAAEALEGAGRFAAGAGRHGAQASHD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0756 | echA5 | - | 100% (257) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_1114 | echA1 | 4e-35 | 38.02% (242) | enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_4076 | echA19 | 1e-29 | 34.29% (245) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0694 | echA5 | 1e-126 | 88.58% (254) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_5084 | - | 1e-114 | 79.12% (249) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv0675 | echA5 | 1e-126 | 88.58% (254) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 3e-25 | 34.16% (202) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_3857c | - | 1e-106 | 75.81% (248) | enoyl-CoA hydratase |
| M. marinum M | MMAR_1004 | echA5 | 1e-143 | 99.22% (257) | enoyl-CoA hydratase, EchA5 |
| M. avium 104 | MAV_4497 | - | 1e-125 | 88.19% (254) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_1390 | - | 1e-116 | 81.50% (254) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_2627 | - | 1e-113 | 80.00% (250) | PUTATIVE enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_1272 | - | 1e-113 | 79.44% (248) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5084|M.gilvum_PYR-GCK -------------MTIRVEKNGAVTTVIMDRPQARNAVDGPTALALHAAF
Mvan_1272|M.vanbaalenii_PYR-1 MSGTAGRSEATRGESIRVEKSGAVTTVVMDRPQARNAVDGPTAMELHAAF
MUL_0756|M.ulcerans_Agy99 -----------MSDLVQVERNGPVTTVIINRPQARNAVNGPTAAALYSAF
MMAR_1004|M.marinum_M -----------MSDLVQVERNGPVTTVIINRPQARNAVNGPTAAALYSAF
Mb0694|M.bovis_AF2122/97 -----------MSDLVRVERKGRVTTVILNRPASRNAVNGPTAAALCAAF
Rv0675|M.tuberculosis_H37Rv -----------MSDLVRVERKGRVTTVILNRPASRNAVNGPTAAALCAAF
MAV_4497|M.avium_104 -----------MSDPVRIERNGPVTTVIINRPAARNAVNGPTAAALYAAF
MSMEG_1390|M.smegmatis_MC2_155 -----------MSEPVRIERNGPVTTVIIDRPEARNAVNGPTAAALFAAF
TH_2627|M.thermoresistible__bu -----------MTKPVRIERDGPVTTVIIDRPEARNAVNGPTAAALYAAF
MAB_3857c|M.abscessus_ATCC_199 -------MSEEMQPAVRVEKAGPVTTVILNRPHARNAVDGPTAAALLAAF
MLBr_02402|M.leprae_Br4923 ----------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAA
: :: * : ::** : **::. : *
Mflv_5084|M.gilvum_PYR-GCK DEFDKDDSASVAVLWGDHGTFCAGADLKAMGTADSNPVHRTGPGPMGPTR
Mvan_1272|M.vanbaalenii_PYR-1 DEFDKDESASVAVLWGDNGTFCAGADLKAMGTENSNPVHRTGPGPMGPSR
MUL_0756|M.ulcerans_Agy99 AEFDRDESASVAVLCGNGGTFCAGADLKAFGTAEANAVHRTGPGPMGRSR
MMAR_1004|M.marinum_M AEFDRDESASVAVLCGNGGTFCAGADLKAFGTAEANAVHRTGPGPMGPSR
Mb0694|M.bovis_AF2122/97 EQFDRDDAASVAVLWGAGGTFCAGADLKAFGTPEANSVHRTGPGPMGPSR
Rv0675|M.tuberculosis_H37Rv EQFDRDDAASVAVLWGAGGTFCAGADLKAFGTPEANSVHRTGPGPMGPSR
MAV_4497|M.avium_104 EEFDRDDSASVAVLWGEGGTFCAGADLKAFGTPEANAVHRSGPGPMGPTR
MSMEG_1390|M.smegmatis_MC2_155 EEFDADDTASVAVLTGANGTFCAGADLKAFGTPEANQVHREGPGPMGPSR
TH_2627|M.thermoresistible__bu DEFDRDEDAAVAVLWGANGTFCAGADLKAFGTPEANPVHRSGPGPMGPTR
MAB_3857c|M.abscessus_ATCC_199 TEFDADPEASVAVLWGDNGTFCAGADLKAMGTDRGNELHPHGPGPMGPSR
MLBr_02402|M.leprae_Br4923 KELDIDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFFSAWGKL
::* * ... :: * .*.****:* :.: . . . . .
Mflv_5084|M.gilvum_PYR-GCK MVLSKPVIAAISGYAVAGGLELALWCDLRIVEQDAVLGVFCRRWGVPLID
Mvan_1272|M.vanbaalenii_PYR-1 MVLSKPVIAAVSGYAVAGGLELALWCDLRIVEQDAVMGVFCRRWGVPLID
MUL_0756|M.ulcerans_Agy99 MMLSKPVIAAVSGYAVAGGLELALWCDLRVAEQDSVFGVFCRRWGVPLID
MMAR_1004|M.marinum_M MMLSKPVIAAVSGYAVAGGLELALWCDLRVAEQDAVFGVFCRRWGVPLID
Mb0694|M.bovis_AF2122/97 MMLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLID
Rv0675|M.tuberculosis_H37Rv MMLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLID
MAV_4497|M.avium_104 MVLSKPVIAAVSGYAVAGGLELAIWCDLRVVEQDAVFGVFCRRWGVPLID
MSMEG_1390|M.smegmatis_MC2_155 MDLSKPVIAAISGYAVAGGLELALWCDLRVVDEDATMGVFCRRWGVPLID
TH_2627|M.thermoresistible__bu MVLSKPVIAAVSGYAVAGGLELALWTDLRIVEQDAIMGVFCRRWGVPLID
MAB_3857c|M.abscessus_ATCC_199 LRLSKPVIAAISGHAVAGGIELALWCDLRVVEEDAVLGVFCRRWGVPLID
MLBr_02402|M.leprae_Br4923 AAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGM
: .*:***::*:*:.** ***: ** :. : : :* : **
Mflv_5084|M.gilvum_PYR-GCK GGTVRLPRLIGHGRAMDLILTGRAVDADEAKSIGLANRVVPSGAARQEAE
Mvan_1272|M.vanbaalenii_PYR-1 GGTVRLPRLIGHSRAMDLILTGRAVDADEAYAIGLANRVVPKGEARQRAE
MUL_0756|M.ulcerans_Agy99 GGTVRLPRLIGHSRAMDMILTGRAVQADEALAIGLANRVVPNGQARQAAE
MMAR_1004|M.marinum_M GGTVRLPRLIGHSRAMDMILTGRAVQADEALAIGLANRVVPNGQARQAAE
Mb0694|M.bovis_AF2122/97 GGTVRLPRLIGHSRAMDMILTGRGVPADEALAMGLANRVVPKGQARQAAE
Rv0675|M.tuberculosis_H37Rv GGTVRLPRLIGHSRAMDMILTGRGVPADEALAMGLANRVVPKGQARQAAE
MAV_4497|M.avium_104 GGTVRLPRLIGHSRAMDMILTGRAVAADEAQAIGLANRVVPKGQSRRAAE
MSMEG_1390|M.smegmatis_MC2_155 GGTVRLPRLIGHSRAMDLILTGRAVDAAEAYAIGLANRVVPTGQARQAAE
TH_2627|M.thermoresistible__bu GGTVRLPRLIGESRAMDLILTGRPVDADEALAIGLANRVVPTGEARARAE
MAB_3857c|M.abscessus_ATCC_199 GGTIRLPRLIGHSRAMDLILTGRPVHANEALDIGLVNRVVARGQAREAAE
MLBr_02402|M.leprae_Br4923 GGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAK
**: **.* **..:***:***** : * ** **..*** . *:
Mflv_5084|M.gilvum_PYR-GCK DLAAELAALPQQCLRSDRMSALNQWG--KSESDAMDVEFGSLSRVAAESL
Mvan_1272|M.vanbaalenii_PYR-1 ELAAELAALPQQCMRSDRMSLLNQWG--MSEAEAMDVEFGSLSRVAAESL
MUL_0756|M.ulcerans_Agy99 ELAAQLAALPQQCLRSDRLSALQQWG--LPESAALDLEFASISRVAAEAL
MMAR_1004|M.marinum_M ELAAQLAALPQQCLRSDRLSALQQWG--LPESAALDLEFASISRVAAEAL
Mb0694|M.bovis_AF2122/97 ELAAQLAALPQQCLRSDRLSALHQWG--LPESAALDLEFASIARVAGEAL
Rv0675|M.tuberculosis_H37Rv ELAAQLAALPQQCLRSDRLSALHQWG--LPESAALDLEFASIARVAGEAL
MAV_4497|M.avium_104 ELAAQLAALPQQCLRSDRLSALHQWG--ATESEALDFEFASISRVAAEAN
MSMEG_1390|M.smegmatis_MC2_155 ELAADLARLPQQCMRADRLSALHQWG--ESENAAMDFEFASISRVKDEAM
TH_2627|M.thermoresistible__bu ELAAELARLPQQCLRADRMSVLQQWG--KREAEAMDFEFASISKVSHEAA
MAB_3857c|M.abscessus_ATCC_199 TLAAEIAAFPQQCVRADRDSAIAQWG--MAEEAALDNEFGSIERVATEAL
MLBr_02402|M.leprae_Br4923 AVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQS
:*: :: :.:.. * : : .: * : .: * :
Mflv_5084|M.gilvum_PYR-GCK EGAARFSAGTGRHGAKT---------
Mvan_1272|M.vanbaalenii_PYR-1 EGAVRFAEGAGRHGAPG---------
MUL_0756|M.ulcerans_Agy99 EGAGRFAAGAGRHGAQASHD------
MMAR_1004|M.marinum_M EGAGRFAAGAGRHGAQASHD------
Mb0694|M.bovis_AF2122/97 EGARRFAAGAGRHGAPAPRAEQGDTL
Rv0675|M.tuberculosis_H37Rv EGARRFAAGAGRHGAPAPRAEQGDTL
MAV_4497|M.avium_104 EGAGRFAAGAGRHGASAV--------
MSMEG_1390|M.smegmatis_MC2_155 HGAGRFAAGAGRHGANA---------
TH_2627|M.thermoresistible__bu AGASRFAAGAGRHGAPA---------
MAB_3857c|M.abscessus_ATCC_199 EGAGRFAAGEGRHGAGV---------
MLBr_02402|M.leprae_Br4923 EGMAAFIEKRAPQFTHR---------
* * . : :