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MSRLSEPSPYVEFDRRQWRALRMSTPLALTEAELIGLRGLGEQIDLLEVEEVFLPLARLLHLQVAARQRL FAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELER RNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHLHYNIIPGAKQVVRHPDILILEGLNVLQTGP TLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRSTAFANPESHFHHYSALPDPEAVVAAREIWRTINRPN LVENILPTRPRATLVLRKDADHSIKRLRLRKL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0189 | coaA | - | 100% (312) | pantothenate kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1122c | coaA | 1e-173 | 95.19% (312) | pantothenate kinase |
| M. gilvum PYR-GCK | Mflv_2058 | - | 1e-155 | 84.29% (312) | pantothenate kinase |
| M. tuberculosis H37Rv | Rv1092c | coaA | 1e-173 | 95.19% (312) | pantothenate kinase |
| M. leprae Br4923 | MLBr_01954 | coaA | 1e-167 | 92.63% (312) | pantothenate kinase |
| M. abscessus ATCC 19977 | MAB_1234c | - | 1e-149 | 83.65% (312) | pantothenate kinase |
| M. marinum M | MMAR_4376 | coaA | 1e-180 | 100.00% (312) | pantothenate kinase CoaA |
| M. avium 104 | MAV_1214 | coaA | 1e-164 | 93.05% (302) | pantothenate kinase |
| M. smegmatis MC2 155 | MSMEG_5252 | coaA | 1e-156 | 85.90% (312) | pantothenate kinase |
| M. thermoresistible (build 8) | TH_2162 | coaA | 1e-154 | 83.01% (312) | Probable pantothenate kinase coaA (Pantothenic acid kinase) |
| M. vanbaalenii PYR-1 | Mvan_4658 | - | 1e-154 | 83.97% (312) | pantothenate kinase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0189|M.ulcerans_Agy99 MSRLSEPSPYVEFDRRQWRALRMSTPLALTEAELIGLRGLGEQIDLLEVE
MMAR_4376|M.marinum_M MSRLSEPSPYVEFDRRQWRALRMSTPLALTEAELIGLRGLGEQIDLLEVE
Mb1122c|M.bovis_AF2122/97 MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVE
Rv1092c|M.tuberculosis_H37Rv MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVE
MLBr_01954|M.leprae_Br4923 MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVE
MAV_1214|M.avium_104 ----------MEFDRKQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVE
MAB_1234c|M.abscessus_ATCC_199 MPRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVA
Mflv_2058|M.gilvum_PYR-GCK MARLSEPSPYVEFDRAQWRALRMSTPLKLTEDELVRLRGIGEKIDLLEVE
Mvan_4658|M.vanbaalenii_PYR-1 MARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELVRLRGLGEKIDLLEVE
MSMEG_5252|M.smegmatis_MC2_155 MPRPSEPSPYVEFDRSQWRSLRMSTPLKLSEDELVRLRGMGEKLDLLEVE
TH_2162|M.thermoresistible__bu MARLNEPSPYVEFDRTQWRALRKSTPLKLTEEEVVKLRGLGEKLDLLEVE
:**** ***:** **** *:* *:: ***:**::** **
MUL_0189|M.ulcerans_Agy99 EVFLPLARLLHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
MMAR_4376|M.marinum_M EVFLPLARLLHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
Mb1122c|M.bovis_AF2122/97 EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
Rv1092c|M.tuberculosis_H37Rv EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
MLBr_01954|M.leprae_Br4923 EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPGRPVPFIIGVAGSVA
MAV_1214|M.avium_104 EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFVIGVAGSVA
MAB_1234c|M.abscessus_ATCC_199 EVYLPLARLIHLQVAARQRLFAATATFLG--DQHPDRLVPFVIGVAGSVA
Mflv_2058|M.gilvum_PYR-GCK EVYLPLARLIHLQVAARQALFATTADFLGEPQQNPDRPVPFVIGVAGSVA
Mvan_4658|M.vanbaalenii_PYR-1 EVYLPLARLIHLQVAARQALFATTAQFLGEPQQNPDRPVPFIIGVAGSVA
MSMEG_5252|M.smegmatis_MC2_155 EVYLPLARLIHLQVAARQRLFATTAEFLGEPQQNPDRPVPFIIGVAGSVA
TH_2162|M.thermoresistible__bu EVYLPLARLIHLQVAARQRLFAATAEFLGEPVDSQDRPVPFIIGVAGSVA
**:******:******** ***:** *** : .* ***:********
MUL_0189|M.ulcerans_Agy99 VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELERRNLMHRKGFP
MMAR_4376|M.marinum_M VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELERRNLMHRKGFP
Mb1122c|M.bovis_AF2122/97 VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFP
Rv1092c|M.tuberculosis_H37Rv VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFP
MLBr_01954|M.leprae_Br4923 VGKSTTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFP
MAV_1214|M.avium_104 VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELDRRNLMHRKGFP
MAB_1234c|M.abscessus_ATCC_199 VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELSRRNIMHRKGFP
Mflv_2058|M.gilvum_PYR-GCK VGKSTTARVLQALLARWEHHPRVDLVTTDGFLYSNSELSRRNLMHRKGFP
Mvan_4658|M.vanbaalenii_PYR-1 VGKSTTARVLQALLARWEHHPRVDLVTTDGFLYSNSELSRRNLMHRKGFP
MSMEG_5252|M.smegmatis_MC2_155 VGKSTTARVLQALLARWEHHPRVDLVTTDGFLYPNAELARRNLMHRKGFP
TH_2162|M.thermoresistible__bu VGKSTTARVLQALLARWEHHPRVDLVTTDGFLYPNAELARRNIMHRKGFP
*****************:**.************.*:** ***:*******
MUL_0189|M.ulcerans_Agy99 ESYNRRALMRFVTSVKSGSDYACAPVYSHLHYNIIPGAKQVVRHPDILIL
MMAR_4376|M.marinum_M ESYNRRALMRFVTSVKSGSDYACAPVYSHLHYNIIPGAKQVVRHPDILIL
Mb1122c|M.bovis_AF2122/97 ESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILIL
Rv1092c|M.tuberculosis_H37Rv ESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILIL
MLBr_01954|M.leprae_Br4923 ESYNRRALMRFVTSVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILIL
MAV_1214|M.avium_104 ESYNRRALMRFVTSVKSGSDYACAPVYSHLKYDIIPGAKHVVRHPDILIL
MAB_1234c|M.abscessus_ATCC_199 ESYNRRGLLRFVTEVKSGAREVTAPVYSHLLYDIIKNEKHVVQQPDILIL
Mflv_2058|M.gilvum_PYR-GCK ESYDRRGLMRFVTTVKSGSDVACAPVYSHLLYDIVPGEKQIIEHPDILIL
Mvan_4658|M.vanbaalenii_PYR-1 ESYDRRGLMRFVTAIKSGADAACAPVYSHLLYDIVAGEKQIIEHPDILIL
MSMEG_5252|M.smegmatis_MC2_155 ESYNRRALMRFVTAVKSGADEAAAPVYSHLLYDIVPGEYQIVRHPDILIL
TH_2162|M.thermoresistible__bu ESYDRRALMRFVTAVKSGAEEACVPVYSHLLYDIVPGEKQIIRRPDILIL
***:**.*:**** :***: . .****** *: : . :::.:******
MUL_0189|M.ulcerans_Agy99 EGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRSTAFANP
MMAR_4376|M.marinum_M EGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRSTAFANP
Mb1122c|M.bovis_AF2122/97 EGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADP
Rv1092c|M.tuberculosis_H37Rv EGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADP
MLBr_01954|M.leprae_Br4923 EGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFLAMRGTAFADP
MAV_1214|M.avium_104 EGLNVLQTGPTLMVSDLFDFGIYVDARIEDIEQWYISRFLAMRSTAFADP
MAB_1234c|M.abscessus_ATCC_199 EGLNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAMRSTSFANP
Mflv_2058|M.gilvum_PYR-GCK EGLNVLQTGPALMVSDLFDFSVYVDARIEDIENWYISRFLKMREGAFADP
Mvan_4658|M.vanbaalenii_PYR-1 EGLNVLQTGPALMVSDLFDFSVYVDARIEDIENWYISRFLSMRAGAFADP
MSMEG_5252|M.smegmatis_MC2_155 EGLNVLQTGPALMVSDLFDFSVYVDARIEDIEQWYISRFLTMRSTAFADP
TH_2162|M.thermoresistible__bu EGLNVLQTGPALMVSDLFDFSVYVDARIDDIEQWYISRFLTMRSTAFANP
**********:*********.:******:***:**:**** ** :**:*
MUL_0189|M.ulcerans_Agy99 ESHFHHYSALPDPEAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
MMAR_4376|M.marinum_M ESHFHHYSALPDPEAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
Mb1122c|M.bovis_AF2122/97 ESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
Rv1092c|M.tuberculosis_H37Rv ESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
MLBr_01954|M.leprae_Br4923 ESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDA
MAV_1214|M.avium_104 ESHFHHYAALNDTKAVAAAREIWRSINRPNLVENILPTRPRATLVLRKDA
MAB_1234c|M.abscessus_ATCC_199 SSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVLRKDA
Mflv_2058|M.gilvum_PYR-GCK ASHFHHYSTLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDS
Mvan_4658|M.vanbaalenii_PYR-1 ASHFHHYSTLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDS
MSMEG_5252|M.smegmatis_MC2_155 ASHFHSYSTLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDA
TH_2162|M.thermoresistible__bu ASHFHHYATLTDEQAIFAARDIWHSINRPNLIENILPTRPRATLVLRKDS
**** *: : * :* **::**::** ***:*****************:
MUL_0189|M.ulcerans_Agy99 DHSIKRLRLRKL
MMAR_4376|M.marinum_M DHSIKRLRLRKL
Mb1122c|M.bovis_AF2122/97 DHSINRLRLRKL
Rv1092c|M.tuberculosis_H37Rv DHSINRLRLRKL
MLBr_01954|M.leprae_Br4923 DHSINRLRLRKL
MAV_1214|M.avium_104 DHSINRLRLRKL
MAB_1234c|M.abscessus_ATCC_199 DHSINRLRLRKL
Mflv_2058|M.gilvum_PYR-GCK DHSINRLRLRKL
Mvan_4658|M.vanbaalenii_PYR-1 DHSINRLRLRKL
MSMEG_5252|M.smegmatis_MC2_155 DHSINRLRLRKL
TH_2162|M.thermoresistible__bu DHSINRIRLRKL
****:*:*****