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M. avium 104 MAV_1214 (coaA)

annotation: pantothenate kinase
coordinates: 1159962 - 1160870
length: 302

EFDRKQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEP
QQNPDRPVPFVIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELDRRNLMHRKGFPE
SYNRRALMRFVTSVKSGSDYACAPVYSHLKYDIIPGAKHVVRHPDILILEGLNVLQTGPTLMVSDLFDFG
IYVDARIEDIEQWYISRFLAMRSTAFADPESHFHHYAALNDTKAVAAAREIWRSINRPNLVENILPTRPR
ATLVLRKDADHSINRLRLRKL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1214coaA-100% (302)pantothenate kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1122ccoaA1e-16794.70% (302) pantothenate kinase
M. gilvum PYR-GCKMflv_2058-1e-15286.09% (302) pantothenate kinase
M. tuberculosis H37RvRv1092ccoaA1e-16794.70% (302) pantothenate kinase
M. leprae Br4923MLBr_01954coaA1e-16694.04% (302) pantothenate kinase
M. abscessus ATCC 19977MAB_1234c-1e-14786.42% (302) pantothenate kinase
M. marinum MMMAR_4376coaA1e-16493.05% (302) pantothenate kinase CoaA
M. smegmatis MC2 155MSMEG_5252coaA1e-15387.42% (302) pantothenate kinase
M. thermoresistible (build 8)TH_2162coaA1e-15084.77% (302) Probable pantothenate kinase coaA (Pantothenic acid kinase)
M. ulcerans Agy99MUL_0189coaA1e-16493.05% (302) pantothenate kinase
M. vanbaalenii PYR-1Mvan_4658-1e-15185.10% (302) pantothenate kinase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1122c|M.bovis_AF2122/97           MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVE
Rv1092c|M.tuberculosis_H37Rv        MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVE
MMAR_4376|M.marinum_M               MSRLSEPSPYVEFDRRQWRALRMSTPLALTEAELIGLRGLGEQIDLLEVE
MUL_0189|M.ulcerans_Agy99           MSRLSEPSPYVEFDRRQWRALRMSTPLALTEAELIGLRGLGEQIDLLEVE
MLBr_01954|M.leprae_Br4923          MPRLSEPSPYVEFDRKQWRALRMSTPLALTEEELIGLRGLGEQIDLLEVE
MAV_1214|M.avium_104                ----------MEFDRKQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVE
MAB_1234c|M.abscessus_ATCC_199      MPRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVA
Mflv_2058|M.gilvum_PYR-GCK          MARLSEPSPYVEFDRAQWRALRMSTPLKLTEDELVRLRGIGEKIDLLEVE
Mvan_4658|M.vanbaalenii_PYR-1       MARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELVRLRGLGEKIDLLEVE
MSMEG_5252|M.smegmatis_MC2_155      MPRPSEPSPYVEFDRSQWRSLRMSTPLKLSEDELVRLRGMGEKLDLLEVE
TH_2162|M.thermoresistible__bu      MARLNEPSPYVEFDRTQWRALRKSTPLKLTEEEVVKLRGLGEKLDLLEVE
                                              :**** ***:** **** *:* *:: ***:**::** ** 

Mb1122c|M.bovis_AF2122/97           EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
Rv1092c|M.tuberculosis_H37Rv        EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
MMAR_4376|M.marinum_M               EVFLPLARLLHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
MUL_0189|M.ulcerans_Agy99           EVFLPLARLLHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
MLBr_01954|M.leprae_Br4923          EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPGRPVPFIIGVAGSVA
MAV_1214|M.avium_104                EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFVIGVAGSVA
MAB_1234c|M.abscessus_ATCC_199      EVYLPLARLIHLQVAARQRLFAATATFLG--DQHPDRLVPFVIGVAGSVA
Mflv_2058|M.gilvum_PYR-GCK          EVYLPLARLIHLQVAARQALFATTADFLGEPQQNPDRPVPFVIGVAGSVA
Mvan_4658|M.vanbaalenii_PYR-1       EVYLPLARLIHLQVAARQALFATTAQFLGEPQQNPDRPVPFIIGVAGSVA
MSMEG_5252|M.smegmatis_MC2_155      EVYLPLARLIHLQVAARQRLFATTAEFLGEPQQNPDRPVPFIIGVAGSVA
TH_2162|M.thermoresistible__bu      EVYLPLARLIHLQVAARQRLFAATAEFLGEPVDSQDRPVPFIIGVAGSVA
                                    **:******:******** ***:** ***   :  .* ***:********

Mb1122c|M.bovis_AF2122/97           VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFP
Rv1092c|M.tuberculosis_H37Rv        VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFP
MMAR_4376|M.marinum_M               VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELERRNLMHRKGFP
MUL_0189|M.ulcerans_Agy99           VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELERRNLMHRKGFP
MLBr_01954|M.leprae_Br4923          VGKSTTARVLQALLARWDHHTRVDLVTTDGFLYPNAELGRRNLMHRKGFP
MAV_1214|M.avium_104                VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELDRRNLMHRKGFP
MAB_1234c|M.abscessus_ATCC_199      VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELSRRNIMHRKGFP
Mflv_2058|M.gilvum_PYR-GCK          VGKSTTARVLQALLARWEHHPRVDLVTTDGFLYSNSELSRRNLMHRKGFP
Mvan_4658|M.vanbaalenii_PYR-1       VGKSTTARVLQALLARWEHHPRVDLVTTDGFLYSNSELSRRNLMHRKGFP
MSMEG_5252|M.smegmatis_MC2_155      VGKSTTARVLQALLARWEHHPRVDLVTTDGFLYPNAELARRNLMHRKGFP
TH_2162|M.thermoresistible__bu      VGKSTTARVLQALLARWEHHPRVDLVTTDGFLYPNAELARRNIMHRKGFP
                                    *****************:**.************.*:** ***:*******

Mb1122c|M.bovis_AF2122/97           ESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILIL
Rv1092c|M.tuberculosis_H37Rv        ESYNRRALMRFVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILIL
MMAR_4376|M.marinum_M               ESYNRRALMRFVTSVKSGSDYACAPVYSHLHYNIIPGAKQVVRHPDILIL
MUL_0189|M.ulcerans_Agy99           ESYNRRALMRFVTSVKSGSDYACAPVYSHLHYNIIPGAKQVVRHPDILIL
MLBr_01954|M.leprae_Br4923          ESYNRRALMRFVTSVKSGADYACAPVYSHLRYDTIPGAKHVVRHPDILIL
MAV_1214|M.avium_104                ESYNRRALMRFVTSVKSGSDYACAPVYSHLKYDIIPGAKHVVRHPDILIL
MAB_1234c|M.abscessus_ATCC_199      ESYNRRGLLRFVTEVKSGAREVTAPVYSHLLYDIIKNEKHVVQQPDILIL
Mflv_2058|M.gilvum_PYR-GCK          ESYDRRGLMRFVTTVKSGSDVACAPVYSHLLYDIVPGEKQIIEHPDILIL
Mvan_4658|M.vanbaalenii_PYR-1       ESYDRRGLMRFVTAIKSGADAACAPVYSHLLYDIVAGEKQIIEHPDILIL
MSMEG_5252|M.smegmatis_MC2_155      ESYNRRALMRFVTAVKSGADEAAAPVYSHLLYDIVPGEYQIVRHPDILIL
TH_2162|M.thermoresistible__bu      ESYDRRALMRFVTAVKSGAEEACVPVYSHLLYDIVPGEKQIIRRPDILIL
                                    ***:**.*:**** :***:  . .****** *: : .  :::.:******

Mb1122c|M.bovis_AF2122/97           EGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADP
Rv1092c|M.tuberculosis_H37Rv        EGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTAFADP
MMAR_4376|M.marinum_M               EGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRSTAFANP
MUL_0189|M.ulcerans_Agy99           EGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRSTAFANP
MLBr_01954|M.leprae_Br4923          EGLNVLQTGPTLMVSDLFDFSLYVDARIQDIEQWYVSRFLAMRGTAFADP
MAV_1214|M.avium_104                EGLNVLQTGPTLMVSDLFDFGIYVDARIEDIEQWYISRFLAMRSTAFADP
MAB_1234c|M.abscessus_ATCC_199      EGLNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAMRSTSFANP
Mflv_2058|M.gilvum_PYR-GCK          EGLNVLQTGPALMVSDLFDFSVYVDARIEDIENWYISRFLKMREGAFADP
Mvan_4658|M.vanbaalenii_PYR-1       EGLNVLQTGPALMVSDLFDFSVYVDARIEDIENWYISRFLSMRAGAFADP
MSMEG_5252|M.smegmatis_MC2_155      EGLNVLQTGPALMVSDLFDFSVYVDARIEDIEQWYISRFLTMRSTAFADP
TH_2162|M.thermoresistible__bu      EGLNVLQTGPALMVSDLFDFSVYVDARIDDIEQWYISRFLTMRSTAFANP
                                    **********:*********.:******:***:**:**** **  :**:*

Mb1122c|M.bovis_AF2122/97           ESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
Rv1092c|M.tuberculosis_H37Rv        ESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
MMAR_4376|M.marinum_M               ESHFHHYSALPDPEAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
MUL_0189|M.ulcerans_Agy99           ESHFHHYSALPDPEAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
MLBr_01954|M.leprae_Br4923          ESHFHHYSALTDSKAIIAAREIWRSINRPNLVENILPTRPRATLVLRKDA
MAV_1214|M.avium_104                ESHFHHYAALNDTKAVAAAREIWRSINRPNLVENILPTRPRATLVLRKDA
MAB_1234c|M.abscessus_ATCC_199      SSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVLRKDA
Mflv_2058|M.gilvum_PYR-GCK          ASHFHHYSTLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDS
Mvan_4658|M.vanbaalenii_PYR-1       ASHFHHYSTLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDS
MSMEG_5252|M.smegmatis_MC2_155      ASHFHSYSTLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDA
TH_2162|M.thermoresistible__bu      ASHFHHYATLTDEQAIFAARDIWHSINRPNLIENILPTRPRATLVLRKDS
                                     **** *: : * :*  **::**::** ***:*****************:

Mb1122c|M.bovis_AF2122/97           DHSINRLRLRKL
Rv1092c|M.tuberculosis_H37Rv        DHSINRLRLRKL
MMAR_4376|M.marinum_M               DHSIKRLRLRKL
MUL_0189|M.ulcerans_Agy99           DHSIKRLRLRKL
MLBr_01954|M.leprae_Br4923          DHSINRLRLRKL
MAV_1214|M.avium_104                DHSINRLRLRKL
MAB_1234c|M.abscessus_ATCC_199      DHSINRLRLRKL
Mflv_2058|M.gilvum_PYR-GCK          DHSINRLRLRKL
Mvan_4658|M.vanbaalenii_PYR-1       DHSINRLRLRKL
MSMEG_5252|M.smegmatis_MC2_155      DHSINRLRLRKL
TH_2162|M.thermoresistible__bu      DHSINRIRLRKL
                                    ****:*:*****