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PVSRCCIRGKCRWVGRVQSGCNARFRSGRRSLIGAWCFVDHYGPVSAHMDVAPHPHTGLQTVSWLFSGEV EHRDSAGVHARIRPGELNMMTAGAGICHSEVSVGSGVLHGAQLWVALPDSVRDTGRDFAHYAPAPAVLPG ARARVFIGELAGVRSPVHTFTPLLGAQLDLDAHAELDIEVDPTFEHGVLCDVGDLELAGTALAAGDLGYQ GPDNTAVHVRNVGAQPARLLLLGGTPFAEELVMWWNFVGRNHDEIVSYRQLWQDDDARFGEVVGYQGSVT RLPAPPLPTTRLLPRPLPNREDHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0039 | - | - | 100% (305) | hypothetical protein MUL_0039 |
| M. ulcerans Agy99 | MUL_4766 | - | 3e-17 | 30.29% (241) | hypothetical protein MUL_4766 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0187c | - | 2e-11 | 36.27% (102) | hypothetical protein Mb0187c |
| M. gilvum PYR-GCK | Mflv_0788 | - | 1e-107 | 67.88% (274) | pirin domain-containing protein |
| M. tuberculosis H37Rv | Rv0181c | - | 2e-11 | 36.27% (102) | hypothetical protein Rv0181c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3941c | - | 3e-95 | 60.66% (272) | hypothetical protein MAB_3941c |
| M. marinum M | MMAR_0040 | - | 1e-160 | 96.01% (276) | hypothetical protein MMAR_0040 |
| M. avium 104 | MAV_0038 | - | 1e-121 | 71.69% (272) | hypothetical protein MAV_0038 |
| M. smegmatis MC2 155 | MSMEG_0049 | - | 1e-110 | 68.25% (274) | pirin domain-containing protein |
| M. thermoresistible (build 8) | TH_1360 | - | 3e-69 | 68.16% (179) | pirin domain protein |
| M. vanbaalenii PYR-1 | Mvan_0062 | - | 1e-110 | 68.98% (274) | pirin domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0039|M.ulcerans_Agy99 --------MPVSRCCIRG----------KCRWVGRVQSGCNARFRSGR--
MMAR_0040|M.marinum_M MSNLETAPAEVACCAAQGA-------GIEVLHPREVPLGGPRAIRVQRTL
MAV_0038|M.avium_104 MSNLEVAPAEVACAASRDRDASP---AVQILRPREVPLGGPRALRVQRTL
Mflv_0788|M.gilvum_PYR-GCK MSNTDTAPDEVDCVASGFAG---------VLHPREVPLGGPRAIRVRRTL
Mvan_0062|M.vanbaalenii_PYR-1 MSNTDPAPAEVDCVASPFAG---------VLHPREVPLGGPRAIRVRRTL
MSMEG_0049|M.smegmatis_MC2_155 MSNTDVAPSEVTCGPSRFTG---------VLHAREVPLGGPRAIAVRRTL
MAB_3941c|M.abscessus_ATCC_199 MSNTETTPTETRCEGGPCPLDDAGRPVVEILTPREVPLGGPRAMTVLRTL
TH_1360|M.thermoresistible__bu MSNTETAPVEVTCGVEPFTG--------AVLRPREVPLGGPRAMPVRRTL
Mb0187c|M.bovis_AF2122/97 ----MTATVEIRRAADRAVT--------------TTSWLKSRHSFSFGDH
Rv0181c|M.tuberculosis_H37Rv ----MTATVEIRRAADRAVT--------------TTSWLKSRHSFSFGDH
.
MUL_0039|M.ulcerans_Agy99 ----RSLIGAWCFVDHYGPVSAH----MDVAPHPHTGLQTVSWLFSGEVE
MMAR_0040|M.marinum_M PQRQRSLIGAWCFVDHYGPVSAH----MDVAPHPHTGLQTVSWLFGGEVE
MAV_0038|M.avium_104 PQRERSLIGAWCFIDHYGPAHTR----MDVPPHPHTGLQTVSWLFSGEVE
Mflv_0788|M.gilvum_PYR-GCK PQRERSLIGAWCFADHYGPHDVRGGTGMDVPPHPHTGLQTVSWLFSGEVE
Mvan_0062|M.vanbaalenii_PYR-1 PQRERSLIGAWCFADHYGPHDVRGGTGMDVPPHPHTGLQTVSWLFSGEVE
MSMEG_0049|M.smegmatis_MC2_155 PQRDRTLIGAWCFADHYGPHDVRSGPGMDVPPHPHTGLQTVSWLFAGEIE
MAB_3941c|M.abscessus_ATCC_199 PQAQRSLIGAWCFADHYGPDDIGQTGGMDVAPHPHTGLQTVSWLFTGEIE
TH_1360|M.thermoresistible__bu PQRKRSLIGAWCFIDHYGPQDVRTGPGMDVAPHPHTGLQTVSWLFAGEIE
Mb0187c|M.bovis_AF2122/97 YDPDNTHHGLLLVNNDDQMEPAS-----GFDPHPHRDMEIVTWVLRGALR
Rv0181c|M.tuberculosis_H37Rv YDPDNTHHGLLLVNNDDQMEPAS-----GFDPHPHRDMEIVTWVLRGALR
.: * . :. .. **** .:: *:*:: * :.
MUL_0039|M.ulcerans_Agy99 HRDSAGVHARIRPGELNMMTAGAGICHSEVSVGSG-VLHGAQLWVALPDS
MMAR_0040|M.marinum_M HRDSAGVHARIRPGELNLMTAGAGICHSEVSVGSG-VLHGAQLWVALPDS
MAV_0038|M.avium_104 HRDSAGVHAAVRPGELNLMTAGAGICHSEVSVGSG-ALHGVQLWVVLPDS
Mflv_0788|M.gilvum_PYR-GCK HRDSAGVHAMVRPGELNLMTAGAGICHSEVSTASTTVLHGAQLWVALPES
Mvan_0062|M.vanbaalenii_PYR-1 HRDSAGVHAMVRPGELNLMTAGAGICHSEVSTGATEILHGAQLWVALPES
MSMEG_0049|M.smegmatis_MC2_155 HRDSGGVHAMVRPGELNLMTAGAGICHSEVSTKAASVLHGVQLWVALPAA
MAB_3941c|M.abscessus_ATCC_199 HRDSSGVHAMVRPGELNLMTGGRGICHSEVSTAQTTTLHGVQLWVALPDE
TH_1360|M.thermoresistible__bu HRDSGGVHAMVRPGELNLMTAGRGICHSEVSTAATEVLHGVQLWVALPDS
Mb0187c|M.bovis_AF2122/97 HQDSAGNSGVIYPGLAQRMSAGTGILHSEMNDSATEPVHFVQMWVIPDAT
Rv0181c|M.tuberculosis_H37Rv HQDSAGNSGVIYPGLAQRMSAGTGILHSEMNDSATEPVHFVQMWVIPDAT
*:**.* . : ** : *:.* ** ***:. :* .*:**
MUL_0039|M.ulcerans_Agy99 VRDTGRDFAHYAPAPAVLPGARARVFIGELAGVRSPVHTFTPLLGAQLDL
MMAR_0040|M.marinum_M ARDTGRDFAHYAPAPAVLPGARARVFIGELAGLRSPVHTFTPLLGAQLDL
MAV_0038|M.avium_104 DRDTARDFAHYAPAPISLPGAQARVFLGELHGSRSPVRTFTPLVGAQIDL
Mflv_0788|M.gilvum_PYR-GCK DRNTERDFAHYVPPARTTGGVTTRVFLGELDGQRSPVHTFTPLLGAQLDL
Mvan_0062|M.vanbaalenii_PYR-1 DRDTDRDFAHYAPTPRQVGAVTTRVFLGELEGQRSPVHTFTPLLGAQLDL
MSMEG_0049|M.smegmatis_MC2_155 ARDTDRDFAHYAPTPRVIGSSTLRVFLGELGDSRSPVHTFTPLLGAQIDL
MAB_3941c|M.abscessus_ATCC_199 SRDAARDFQHYAPDAVVAGGVSLRVFLGTLAGQVSPVRTATPLLGAELLL
TH_1360|M.thermoresistible__bu DRDTARDFIHFVPRPHELDDARLLVFLGDLAGARSPVPTFTPLLGAQIDL
Mb0187c|M.bovis_AF2122/97 GITASYQQQEIDDELLRAGLVTIASGIPGQDAALTLHNSSASLHGAR--L
Rv0181c|M.tuberculosis_H37Rv GITASYQQQEIDDELLRAGLVTIASGIPGQDAALTLHNSSASLHGAR--L
: : . : : : :.* **. *
MUL_0039|M.ulcerans_Agy99 DAHAELDIEVDPTFEHGVLCDVGDLELAGTALAAGDLGYQGPDNTAVHVR
MMAR_0040|M.marinum_M DAHAELDIEVDPTFEHGVLCDAGDLELAGTALAAGDLGYQGPGNTTLHVR
MAV_0038|M.avium_104 GAGAQLDLDLDPDFEHGLLCDAGAVHVDEKPLSVAELAYLGPGRAAVQLR
Mflv_0788|M.gilvum_PYR-GCK DPGVDVTLDVDAGFEHGVLVDRGDVQACGSALQVADLAFQGSGHDRLSLA
Mvan_0062|M.vanbaalenii_PYR-1 DPGAEVSLDVDDRFEHGVLVDRGDVEACGSALAVADLAFQGTGHHRLHLL
MSMEG_0049|M.smegmatis_MC2_155 APGAELTLDVDATFEHGVLLDRGAVEVAGTPLAVADLAYQRPGCHELHLA
MAB_3941c|M.abscessus_ATCC_199 EPHSTARFDVDAGFEHGLLVDTEAIEFSGSRLTRGELGYVGTGVEQLTVT
TH_1360|M.thermoresistible__bu YPNGRLTLDIDPGFEHGVLLDTGEVTVAGAALRX----------XARRAA
Mb0187c|M.bovis_AF2122/97 RPGATVSLPCAPFLHLFVAYGRLTLEGGGELADGDAVRFTDADARGLTAN
Rv0181c|M.tuberculosis_H37Rv RPGATVSLPCAPFLHLFVAYGRLTLEGGGELADGDAVRFTDADARGLTAN
. : :. : . :
MUL_0039|M.ulcerans_Agy99 NVGAQPARLLLLGGTPFAEELVMWWNFVGRNHDEIVSYRQLWQDDDARFG
MMAR_0040|M.marinum_M NIGAQPARLLLLGGTPFAEELVMWWNFVGRNHDEIVSYRQLWQDADARFG
MAV_0038|M.avium_104 NAGDTPGRVLLLGGTPFSEQLVMWWNFVGRSHEDIVGYRRLWEDGDERFG
Mflv_0788|M.gilvum_PYR-GCK NRGDGPARVLLLGGAPFTEELVMWWNFVGRSHDEIVAYREQWQQHDERFG
Mvan_0062|M.vanbaalenii_PYR-1 NRGDIPARVLLLGGTPFTEDLVMWWNFVGRSHEDIARFREQWQNHDARFG
MSMEG_0049|M.smegmatis_MC2_155 NTGTGPARVILLGGLPFGEELVMWWNFVGRSHDDIAAYRELWQDHDARFG
MAB_3941c|M.abscessus_ATCC_199 NPTETTARAILLGGKPFGEQIVMWWNFVGRDHDEIAAFREEWQAESERFG
TH_1360|M.thermoresistible__bu DPGPGTAR---------------------TAGSRCAPNRRRRAPGSRRRG
Mb0187c|M.bovis_AF2122/97 EPSE-----------------VLIWEMHAKLGDSAT--------------
Rv0181c|M.tuberculosis_H37Rv EPSE-----------------VLIWEMHAKLGDSAT--------------
: . .
MUL_0039|M.ulcerans_Agy99 EVVGYQGSVTRLPAPPLPTTRLLPRPLPNRE----DHR
MMAR_0040|M.marinum_M EVVGYQGSVTRLPAPPLPTTRLLPRPLPNRE----DHR
MAV_0038|M.avium_104 AVRGYRGALSRLPAPPLPTARLRPRPIPERKGSTNDNR
Mflv_0788|M.gilvum_PYR-GCK SVDGYTGTVTHLPAPPLPNATLRPRPAPGV--------
Mvan_0062|M.vanbaalenii_PYR-1 AVEGYRGAVTRLPAPPLPNATLRPRRHPGV--------
MSMEG_0049|M.smegmatis_MC2_155 AVSGYTGTLSRLPAPPLPNGRLKPRPNPAG--------
MAB_3941c|M.abscessus_ATCC_199 RVEGYQGAVPRLPAPPLPRVRMVPRRNAPTANPGYATP
TH_1360|M.thermoresistible__bu APPRPSGRPVRAPGSPRAG-------------------
Mb0187c|M.bovis_AF2122/97 --------------------------------------
Rv0181c|M.tuberculosis_H37Rv --------------------------------------